scholarly journals Short-term adverse effects of the apolipoprotein E ϵ4 allele over language function and executive function in healthy older adults

2019 ◽  
Vol Volume 15 ◽  
pp. 1855-1861
Author(s):  
Wei Li ◽  
Qi Qiu ◽  
Lin Sun ◽  
Xia Li ◽  
Shifu Xiao
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Adverse Effects ◽  
Apolipoprotein E ◽  
Language Function ◽  
Short Term ◽  
Healthy Older Adults

Short-term Effects of Whole-Body Vibration on Functional Mobility and Flexibility in Healthy, Older Adults

2014 ◽  
Vol 37 (2) ◽  
pp. 58-64 ◽  
Author(s):  
Taishi Tsuji ◽  
Naruki Kitano ◽  
Kenji Tsunoda ◽  
Erika Himori ◽  
Tomohiro Okura ◽  
...  
Keyword(s):  
Older Adults ◽  
Whole Body Vibration ◽  
Functional Mobility ◽  
Whole Body ◽  
Short Term ◽  
Healthy Older Adults ◽  
Body Vibration ◽  
Short Term Effects

Specific impairments in visuospatial working and short-term memory following low-dose scopolamine challenge in healthy older adults

2008 ◽  
Vol 46 (10) ◽  
pp. 2476-2484 ◽  
Author(s):  
Elizabeth Thomas ◽  
Peter J. Snyder ◽  
Robert H. Pietrzak ◽  
Colleen E. Jackson ◽  
Martin Bednar ◽  
...  
Keyword(s):  
Older Adults ◽  
Low Dose ◽  
Short Term Memory ◽  
Short Term ◽  
Term Memory ◽  
Healthy Older Adults

scholarly journals Effects of White Potato Preparation on Subjective Appetite, Food Intake and Glycemic Response in Healthy Older Adults (P08-083-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Jennifer Lee ◽  
Robena Amalraj ◽  
Neil Brett ◽  
Sarah Proteau ◽  
Alexander Schwartz ◽  
...  
Keyword(s):  
Older Adults ◽  
Food Intake ◽  
Glycemic Response ◽  
Short Term ◽  
White Potato ◽  
Healthy Older Adults ◽  
Meal Skipping ◽  
Treatment Conditions ◽  
Ad Libitum ◽  
All Treatment

Abstract Objectives Although some epidemiological studies have linked potato consumption to obesity, diabetes, and mortality, there are limited studies on the effects of potatoes on appetite, food intake, and glycemic regulation in older adults. Therefore, the objective was to compare the effects of white potato preparation on subjective appetite, short-term food intake, and glycemic response in healthy older adults (>65 y). Methods Using a within-subject, repeated-measures design, 20 participants (age: 70.5 ± 0.7 y; BMI: 24.2 ± 0.6 kg/m2) completed five treatment conditions. Following an overnight fast, participants completed five treatment conditions (∼283 kcal) of baked potatoes, mashed potatoes, fried French fries, white bread, or continued to fast. Treatment meals were matched for available carbohydrates (33.1 g) and total fat (13.7 g). Subjective appetite and glycemic response were measured at baseline and over 120 min post-meal consumption using visual analogue scales and capillary blood samples, respectively. An ad libitum pizza lunch was provided to measure food intake at 120 min. Results Change from baseline subjective appetite and subjective appetite incremental area under the curve (iAUC) were lower after all treatment meals compared with meal skipping (P < 0.01). Ad libitum pizza lunch food intake was lower after all treatment meals compared with meal skipping by 175–215 kcal (P < 0.02). However, cumulative food intake (treatment meal + ad libitum food intake) did not differ among test conditions (P = 0.26). Change from baseline blood glucose and blood glucose iAUC were higher after all treatment meals compared with meal skipping (P < 0.001), but did not differ from each other. Conclusions White potatoes suppressed subjective appetite and short-term food intake compared with meal skipping, suggesting that white potatoes do not bypass regulatory control mechanisms of energy intake in healthy older adults. Funding Sources Alliance for Potato Research & Education.

scholarly journals Naturalistic assessment of executive function and everyday multitasking in healthy older adults

2013 ◽  
Vol 20 (6) ◽  
pp. 735-756 ◽  
Author(s):  
Courtney McAlister ◽  
Maureen Schmitter-Edgecombe
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Healthy Older Adults

scholarly journals Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults

2013 ◽  
Vol 305 (3) ◽  
pp. R216-R223 ◽  
Author(s):  
Micah J. Drummond ◽  
Kyle L. Timmerman ◽  
Melissa M. Markofski ◽  
Dillon K. Walker ◽  
Jared M. Dickinson ◽  
...  
Keyword(s):  
Older Adults ◽  
Skeletal Muscle ◽  
Inflammatory Cytokines ◽  
Muscle Biopsy ◽  
Lean Mass ◽  
Bed Rest ◽  
Short Term ◽  
Tlr4 Signaling ◽  
Adult Skeletal Muscle ◽  
Healthy Older Adults

Bed rest induces significant loss of leg lean mass in older adults. Systemic and tissue inflammation also accelerates skeletal muscle loss, but it is unknown whether inflammation is associated to inactivity-induced muscle atrophy in healthy older adults. We determined if short-term bed rest increases toll-like receptor 4 (TLR4) signaling and pro-inflammatory markers in older adult skeletal muscle biopsy samples. Six healthy, older adults underwent seven consecutive days of bed rest. Muscle biopsies (vastus lateralis) were taken after an overnight fast before and at the end of bed rest. Serum cytokine expression was measured before and during bed rest. TLR4 signaling and cytokine mRNAs associated with pro- and anti-inflammation and anabolism were measured in muscle biopsy samples using Western blot analysis and qPCR. Participants lost ∼4% leg lean mass with bed rest. We found that after bed rest, muscle levels of TLR4 protein expression and interleukin-6 (IL-6), nuclear factor-κB1, interleukin-10, and 15 mRNA expression were increased after bed rest ( P < 0.05). Additionally, the cytokines interferon-γ, and macrophage inflammatory protein-1β, were elevated in serum samples following bed rest ( P < 0.05). We conclude that short-term bed rest in older adults modestly increased some pro- and anti-inflammatory cytokines in muscle samples while systemic changes in pro-inflammatory cytokines were mostly absent. Upregulation of TLR4 protein content suggests that bed rest in older adults increases the capacity to mount an exaggerated, and perhaps unnecessary, inflammatory response in the presence of specific TLR4 ligands, e.g., during acute illness.

The Immediate and Delayed Effects of an Acute Bout of Exercise on Cognitive Performance of Healthy Older Adults

2010 ◽  
Vol 18 (1) ◽  
pp. 87-98 ◽  
Author(s):  
Lisa A. Barella ◽  
Jennifer L. Etnier ◽  
Yu-Kai Chang
Keyword(s):  
Older Adults ◽  
Cognitive Performance ◽  
Stroop Task ◽  
Test Performance ◽  
Acute Exercise ◽  
Short Term ◽  
Color Test ◽  
Acute Bout ◽  
Healthy Older Adults ◽  
Delayed Effects

Research on the acute effects of exercise on cognitive performance by older adults is limited by a focus on nonhealthy populations. Furthermore, the duration of cognitive improvements after exercise has not been examined. Thus, this study was designed to test the immediate and delayed effects of acute exercise on cognitive performance of healthy older adults. Cognitive performance was assessed using the Stroop task. Participants were randomly assigned to an exercise (20 min of walking) or control (sitting quietly) condition. The Stroop task was administered at baseline and at 12 time points after treatment. Acute exercise resulted in better Stroop test performance immediately postexercise; however, the effects were limited to the color test. No effects of exercise on performance were observed for the Stroop interference or inhibition tests. Findings suggest that acute exercise performed by healthy older adults has short-term benefits for speed of processing but does not affect other types of cognitive functioning.

scholarly journals Executive function subcomponents and their relations to everyday functioning in healthy older adults

2016 ◽  
Vol 38 (8) ◽  
pp. 925-940 ◽  
Author(s):  
Courtney McAlister ◽  
Maureen Schmitter-Edgecombe
Keyword(s):  
Older Adults ◽  
Executive Function ◽  
Everyday Functioning ◽  
Healthy Older Adults

scholarly journals Improvement of Cognitive Function after Physical Movement Training in Institutionalized Very Frail Older Adults with Dementia

GeroPsych ◽  
2011 ◽  
Vol 24 (4) ◽  
pp. 197-208 ◽  
Author(s):  
Franka Thurm ◽  
Andrea Scharpf ◽  
Nadine Liebermann ◽  
Stephan Kolassa ◽  
Thomas Elbert ◽  
...  
Keyword(s):  
Older Adults ◽  
Nursing Home Residents ◽  
Control Group ◽  
Cognitive Deterioration ◽  
Physical Frailty ◽  
Short Term ◽  
Healthy Older Adults ◽  
Positive Effects ◽  
Movement Training ◽  
Sum Score

Physical exercise has positive effects on cognitive functioning in both healthy older adults and ambulatory older adults with dementia. The present study investigated whether a 10-week multimodal movement intervention conducted in the seated position can slow cognitive deterioration in demented and physically very frail nursing-home residents. Our analysis revealed that training participants showed no further overall cognitive deterioration throughout the study and a significant improvement in the ADAS-Cog orientation/praxis subscore (p = .04). In contrast, the control group demonstrated a significant decline in the ADAS-Cog sum score (p = .02). These results might be of relevance for geriatric practice since they indicate that a short-term physical intervention – even in the seated position – can decelerate cognitive decline and dementia despite physical frailty.

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