scholarly journals Factors Associated with Medication Adherence Among Patients with Severe Mental Disorders in China: A Propensity Score Matching Study

2020 ◽  
Vol Volume 14 ◽  
pp. 1329-1339
Author(s):  
Lei Dou ◽  
Lili Hu ◽  
Nan Zhang ◽  
Henry Cutler ◽  
Yan Wang ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Mental Disorders ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Severe Mental Disorders ◽  
Factors Associated

Factors Related to Self-Care Ability in Patients With Severe Mental Disorders： Based on Community Patients Investigation in Beijing, China (Preprint)

2021 ◽  
Author(s):  
Chen Chen ◽  
Yun Chen ◽  
Qingzhi Huang ◽  
Shengming Yan ◽  
Junli Zhu
Keyword(s):  
Medication Adherence ◽  
Mental Disorders ◽  
Influencing Factors ◽  
Self Care ◽  
The Self ◽  
Severe Mental Disorders ◽  
Course Of Disease ◽  
Physical Disease ◽  
Targeted Interventions ◽  
Care Course

UNSTRUCTURED Background: Severe Mental Disorders (SMD) have become a topic of increasing interest in research due to their serious consequences for the quality of life and functioning. In the pages that follow, it will be argued that the self-care ability and its influencing factors among SMD patients in Beijing, according to the questionnaire survey in 2019. Methods: The present study aimed to explore the factors influencing the self-care ability of SMD patients. Multi-stage sampling and proportioning sampling were used to take samples. The demographic characteristics of patients were obtained by questionnaires, and the self-care ability was measured by self-made scales. Multiple linear regression was used to analyze the influencing factors. Results: We surveyed 662 people and found that the deficiency of self-care ability is common in SMD patients. Significant relations were found between self-care ability and age, educated levels, guardian care, course of disease and physical disease (P<0.05). From a dimensional perspective, the daily basic activity was associated with educated levels and physical disease (P<0.05); the housework ability was associated with gender, educated levels, source of income, physical disease and medication adherence (P＜0.05); the social function was associated with age, educated levels, source of income, guardian care course of disease, physical disease and medication adherence (P＜0.05). Conclusion: The self-care ability of SMD patients is affected by many factors, including patient characteristics and social factors. Therefore, targeted interventions are needed to help patients restore their self-care ability, which requires the joint efforts of the government and the whole society.

scholarly journals Factors influencing medication adherence among patients with severe mental disorders from the perspective of mental health professionals

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Mengjie Deng ◽  
Shuyi Zhai ◽  
Xuan Ouyang ◽  
Zhening Liu ◽  
Brendan Ross
Keyword(s):  
Mental Health ◽  
Medication Adherence ◽  
Mental Disorders ◽  
Qualitative Study ◽  
Mental Health Professionals ◽  
Health Professionals ◽  
Hunan Province ◽  
Severe Mental Disorders ◽  
Qualitative Approaches ◽  
Factors Influencing

Abstract Background Medication adherence is a common issue influenced by various factors among patients with severe mental disorders worldwide. However, most literature to date has been primarily quantitative and has focused on medication adherence issue from the perspective of patients or their caregivers. Moreover, research focused on medication adherence issue in China is scarce. Present study aims to explore the influential factors of medication adherence among patients with severe mental disorders form the perspective of mental health professionals in Hunan Province, China. Methods A qualitative study was performed in Hunan Province, China with 31 mental health professionals recruited from October to November 2017. And semi-structured interviews or focus group interviews were conducted along with audio recordings of all interviews. Interview transcripts were then coded and analyzed in Nvivo software with standard qualitative approaches. Results Three major themes influencing medication adherence among patients with severe mental disorders were identified as: (1) attitudes towards mental disorder/treatment; (2) inadequate aftercare; (3) resource shortages. Conclusions This qualitative study identified the factors influencing medication adherence among patients with severe mental disorders in China. As a locally driven research study, it provides practical advice on medication adherence promotion for mental health workers and suggests culturally tailored models that improve the management of patients with severe mental disorders in order to reduce economic burden on individual and societal level.

scholarly journals Alternating Lenvatinib and Trans-Arterial Therapy Prolongs Overall Survival in Patients with Inter-Mediate Stage HepatoCellular Carcinoma: A Propensity Score Matching Study

Cancers ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 160
Author(s):  
Shigeo Shimose ◽  
Hideki Iwamoto ◽  
Masatoshi Tanaka ◽  
Takashi Niizeki ◽  
Tomotake Shirono ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Overall Survival ◽  
Propensity Score ◽  
Decision Tree ◽  
Propensity Score Matching ◽  
Intermediate Stage ◽  
Decision Tree Analysis ◽  
Tree Analysis ◽  
Factors Associated ◽  
The Impact

We aimed to evaluate the impact of alternating lenvatinib (LEN) and trans-arterial therapy (AT) in patients with intermediate-stage hepatocellular carcinoma (HCC) after propensity score matching (PSM). This retrospective study enrolled 113 patients with intermediate-stage HCC treated LEN. Patients were classified into the AT (n = 41) or non-AT group (n = 72) according to the post LEN treatment. Overall survival (OS) was calculated using the Kaplan–Meier method and analyzed using a log-rank test after PSM. Factors associated with AT were evaluated using a decision tree analysis. After PSM, there were no significant differences in age, sex, etiology, or albumin-bilirubin (ALBI) score/grade between groups. The survival rate of the AT group was significantly higher than that of the non-AT group (median survival time; not reached vs. 16.3 months, P = 0.01). Independent factors associated with OS were AT and ALBI grade 1 in the Cox regression analysis. In the decision tree analysis, age and ALBI were the first and second splitting variables for AT. In this study, we show that AT may improve prognosis in patients with intermediate-stage HCC. Moreover, alternating LEN and trans-arterial therapy may be recommended for patients below 70 years of age with ALBI grade 1.

scholarly journals Optimal Treatment and Management of Proximal Fifth Metatarsal Fractures

2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0006
Author(s):  
Reinout Heijboer ◽  
Sofie Breuking ◽  
Noortje Hagemeijer ◽  
Daniel Guss ◽  
Christopher DiGiovanni
Keyword(s):  
Risk Factors ◽  
Surgical Treatment ◽  
Propensity Score ◽  
Conservative Treatment ◽  
Propensity Score Matching ◽  
Avulsion Fracture ◽  
Diaphyseal Fracture ◽  
Factors Associated ◽  
Metatarsal Fractures ◽  
Diaphyseal Fractures

Category: Midfoot/Forefoot Introduction/Purpose: Proximal fifth metatarsal fractures (PFMF) are among the most common fractures of the foot, and may be subdivided into tuberosity avulsion fracture, Jones fracture, and proximal diaphyseal fracture. However, for Jones fractures and proximal diaphyseal fractures optimal treatment is still debated in literature. The Torg criteria are used in deciding to treat surgically or conservative, whereby Torg type I and II indicates conservative treatment, and type III indicates surgical treatment. Yet failure rates of both management options vary and derive from small study groups. The aim of this study was to compare failure rates after surgical- and conservative treatment of Jones fractures and proximal diaphyseal fractures, to evaluate the incidence of treatment failure, and to assess factors associated with healing difficulties of PFMF. Methods: A total of 1,133 adult patients that were diagnosed and treated for PFMF between 2005 and 2015 in a tertiary care foot and ankle referral center were included. Retrospective chart review recorded patient demographics, suspected risk factors for impaired healing of PFMF (rheumatoid arthritis, diabetes mellitus, osteoporosis, nutritional and hormonal disorders, foot deformities, (neuropathic) arthropathy of the foot and/or ankle and peripheral neuropathy of the lower extremity), and treatment indication. Multivariable logistic regression analysis was used to determine factors associated with healing difficulties. Propensity score matching was used to minimize selection bias between treatments in Jones fractures and proximal diaphyseal fractures. Results: In total, 489(43.2%) patients were diagnosed with a tuberosity avulsion fracture, 391(34.5%) patients with a Jones fracture and 253(22.3%) patients with a proximal diaphyseal fracture. In the tuberosity fracture group, a nonunion was found in 5.3%(25/473) of the patients treated conservatively and in 0%(0/16) treated operatively. For the Jones fractures and proximal diaphyseal fractures the non-union rate for conservative treatment was 10%(35/337) and 5.9%(14/238), and for surgical treatment 11%(6/54) and 0%(0/15), respectively. No independent risk factors for complicating the healing process of PFMF were identified. With propensity score matching, 37 patients treated operatively were matched to 37 patients undergoing conservative treatment. The risk for a nonunion was lower in the operative group compared to the conservative treatment group (relative risk 0.8, P=0.006). Conclusion: In this propensity-matched cohort, surgical treatment for Jones fractures and proximal diaphyseal fractures were associated with better fracture healing compared to conservative treatment. In addition, no factors were found to be associated with healing difficulties of proximal fifth metatarsal fractures.

scholarly journals The factors associated with natural disease progression from HIV to AIDS in the absence of ART, a propensity score matching analysis

2020 ◽  
Vol 148 ◽  
Author(s):  
X. C. Jia ◽  
Z. H. Xia ◽  
N. Shi ◽  
Y. P. Wang ◽  
Z. X. Luo ◽  
...  
Keyword(s):  
Propensity Score ◽  
Disease Progression ◽  
Propensity Score Matching ◽  
Conditional Logistic Regression ◽  
Sexual Transmission ◽  
Risk Area ◽  
High Risk Area ◽  
Factors Associated ◽  
Propensity Score Matching Analysis ◽  
Cell Counts

Abstract This study aimed at comparing the factors associated with the natural progression between typical progressors (TPs) and rapid progressors (RPs) in HIV-infected individuals. A retrospective study was conducted on 2095 eligible HIV-infected individuals from 1995 to 2016 in a high-risk area of Henan Province, China. Propensity score matching was used to balance covariates, and the conditional logistic regression analyses were performed to explore the factors of natural disease progression among HIV infectors. A total of 379 pairs of RPs and TPs were matched. The standardised difference values of all covariates were less than 10%. HIV-infected individuals transmitted through sexual transmission (odds ratio (OR) 0.56, 95% confidence interval (CI) 0.36–0.85) were more likely to progress to AIDS compared with those infected through contaminated blood. Older age at diagnosis of HIV-infected individuals (OR 0.72, 95% CI 0.58–0.89) exhibited a faster progression to AIDS. HIV-infected individuals identified through a unique survey (OR 7.01, 95% CI 2.99–16.44) were less likely to progress to AIDS compared with those identified through medical institutions. HIV-infected individuals who had higher baseline CD4+T cell counts (OR 3.37, 95% CI 2.59–4.38) had a slower progression to AIDS. These findings provide evidence for natural disease progression from HIV to AIDS between TPs and RPs.

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