scholarly journals The role of homeostatic disorders in development of periodontal generalized inflammatory diseases in patients with β-thalassemya major

2019 ◽  
pp. 115-120
Author(s):  
R. V. Shadlinskaya
Keyword(s):  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Thalassemia Major ◽  
Systemic Diseases ◽  
Acting Out ◽  
The Common ◽  
Direct Acting ◽  
The Way

Periodontitis as a manifestation of the systemic diseases was placed in separated part in the contemporary periodontal diseases classification. It has its own specific traits caused by features of the common pathology. The way as ß-thalassemia major is impacting to periodontium could be recognized as the indirect acting out of the side of dental and occlusal anomalies or direct acting of ß-thalassemia major to the periodontium. The range of the influence on periodontium depends on the degree of intensity of the systemic diseases.

scholarly journals MODERN SUBMISSION OF FORMATION, COMPOSITION AND ROLE OF ORAL (DENTAL) BIOFILM IN DEVELOPMENT OF PERIODONTAL DISEASES

2020 ◽  
Vol 73 (8) ◽  
pp. 1761-1764
Author(s):  
Maria O. Stetsyk ◽  
Andriy O. Stetsyk ◽  
Natalia I. Zhero ◽  
Eugene Y. Kostenko ◽  
Svetlana B. Kostenko ◽  
...  
Keyword(s):  
Detailed Analysis ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Oral Biofilm ◽  
Dental Biofilm ◽  
Periodontal Tissues ◽  
Current Trends ◽  
Oral Biofilms ◽  
Depth Study

The aim: To investigate current trends in the study of oral biofilm and its control. Materials and methods: A research of 32 literature sources has been made and it has been taken into account that some terminological differences in determining objects of study. Conclusions: Detailed analysis of modern domestic and foreign literature argues the necessity of further in-depth study of oral biofilms. Understanding the ethiological factors and mechanisms of the pathogenesis periodontal tissues inflammatory diseases gives the opportunity to treat targetly by destroying complicated sections of the vital activities and oral biofilm microorganisms relationships.

Personality

2016 ◽  
pp. 98-101
Author(s):  
Jonathan Leicester
Keyword(s):  
Personality Traits ◽  
Direct Effect ◽  
Need For Closure ◽  
Common Assumption ◽  
The Real ◽  
Occupational Roles ◽  
The Common ◽  
The Way

The chapter opens by questioning the role of personality traits in causing behaviour, and decides to work with the common assumption that they have an important role. There is an account of the search for the real units or traits of personality. Some of the traits and dispositions, selected for their particularly direct effect on belief, for example, strong need for closure, are briefly described. There is a comment on the way long-standing occupational roles can sometimes modify personality.

scholarly journals Conversations with the Common Law: Exposure, Privacy and Societal Change

2021 ◽  
Vol 52 (3) ◽  
pp. 563-579
Author(s):  
Nicole Moreham
Keyword(s):  
Common Law ◽  
Societal Change ◽  
Growing Up ◽  
Societal Values ◽  
The Common ◽  
The Way

This is an edited version of an inaugural professorial lecture delivered at the Faculty of Law, Te Herenga Waka – Victoria University of Wellington on 16 March 2021 (the promotion to professor having taken place on 1 January 2019). In the address, Professor Moreham asked what the development of new torts of privacy over the last two decades has told us about the way in which common law both shapes and responds to changing societal values. Reflecting on her own experience ''growing up with'' the privacy torts, Professor Moreham considered the role of the legal academic in common law development and showed how conversations between the common law and the society it serves enrich both parties to it.

scholarly journals Late-onset rheumatoid arthritis in a patient with successfully treated IgA nephropathy

2017 ◽  
Vol 89 (8) ◽  
pp. 77-79
Author(s):  
N V Chebotareva ◽  
I N Bobkova ◽  
S V Gulyaev
Keyword(s):  
Rheumatoid Arthritis ◽  
Renal Function ◽  
Iga Nephropathy ◽  
Clinical Case ◽  
Late Onset ◽  
Systemic Diseases ◽  
Radiological Patterns ◽  
The Common ◽  
Reduced Renal Function

The paper describes a rare clinical case of rheumatoid arthritis (RA) that developed in a patient 9 years after diagnosing IgA nephropathy. Kidney disease was characterized by a stable course with moderate urinary syndrome, hypertension, and reduced renal function. Immunosuppressive therapy using glucocorticosteroids and then mycophenolic acid led to remission of nephritis and recovery of renal function. However, the absence of nephritis activity and discontinuation of immunosuppressants was responsible for articular syndrome. The diagnosis of RA is based on its characteristic radiological patterns and immunological characteristics after ruling out a number of systemic diseases and infections. The common pathogenetic components of IgA nephropathy and RA, including the role of rheumatoid factor IgA, are discussed.

scholarly journals Clinical and immunological studies of periodontal inflammatory complications at orthodontic treatment using fixed appliances

2014 ◽  
Vol 95 (1) ◽  
pp. 80-82
Author(s):  
G R Khaliullina ◽  
S L Blashkova
Keyword(s):  
Immune Response ◽  
Orthodontic Treatment ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Orthodontic Appliances ◽  
Periodontal Inflammation ◽  
Fixed Orthodontic Appliances ◽  
Fixed Appliances ◽  
Orthodontic Devices

The review of clinical and immunologic studies of periodontal inflammatory diseases is presented. At present, the most effective tools for treatment of malocclusions are fixed orthodontic appliances (dental braces), but the use of fixed appliances complicates the oral hygiene, predisposes to periodontal and gum inflammation. The rate of complications diagnosed during orthodontic treatment stays high. The principles of periodontal inflammatory diseases (gingivitis, periodontitis) treatment are closely related with the causes and mechanisms of periodontal inflammation. Patients who receive orthodontic treatment using braces should be treated as a group with a high risk for inflammatory periodontal diseases. The orthodontic devices stimulate the directed reorganization of periodontal structures achieving optimal aesthetic and functional standards. Physiology of periodontium restructuring is largely determined by the local and general health before, during and after the orthodontic treatment. This article surveys the mechanisms of periodontal damage, highlighting the important role of immune response. So far, only anecdotal descriptions of immune response on the stages of orthodontic treatment are published.

scholarly journals The Role of gp130 Cytokines in Tuberculosis

Cells ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 2695
Author(s):  
Kristina Ritter ◽  
Jasmin Rousseau ◽  
Christoph Hölscher
Keyword(s):  
Inflammatory Diseases ◽  
Therapeutic Approaches ◽  
Duration Of Treatment ◽  
Common Receptor ◽  
Promising Target ◽  
Increased Risk ◽  
The Common ◽  
Combine Administration ◽  
Cytokine Networks

Protective immune responses to Mycobacterium tuberculosis (Mtb) infection substantially depend on a delicate balance within cytokine networks. Thus, immunosuppressive therapy by cytokine blockers, as successfully used in the management of various chronic inflammatory diseases, is often connected with an increased risk for tuberculosis (TB) reactivation. Hence, identification of alternative therapeutics which allow the treatment of inflammatory diseases without compromising anti-mycobacterial immunity remains an important issue. On the other hand, in the context of novel therapeutic approaches for the management of TB, host-directed adjunct therapies, which combine administration of antibiotics with immunomodulatory drugs, play an increasingly important role, particularly to reduce the duration of treatment. In both respects, cytokines/cytokine receptors related to the common receptor subunit gp130 may serve as promising target candidates. Within the gp130 cytokine family, interleukin (IL)-6, IL-11 and IL-27 are most explored in the context of TB. This review summarizes the differential roles of these cytokines in protection and immunopathology during Mtb infection and discusses potential therapeutic implementations with respect to the aforementioned approaches.

THE USE OF PLATELET AUTOPLASMA IN THE COMPLEX TREATMENT OF PERIODONTAL DISEASES

2021 ◽  
Vol 2 (2) ◽  
pp. 5-8
Author(s):  
M.T. Safarov ◽  
◽  
F.A. Khusanbaeva ◽  
K.M. Tashpulatova ◽  
A.M. Khodjiberganov
Keyword(s):  
Quality Of Life ◽  
Chronic Infection ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Pathological Process ◽  
Systemic Diseases ◽  
General State ◽  
Complex Treatment ◽  
Periodontal Tissues

The search for new ways of early detection and improving the effectiveness of treatinginflammatory periodontal diseases is one of the urgent tasks in modern dentistry. Inflammatory diseases in the periodontal tissues lead to the loss of teeth, the appearance offoci of chronic infection in the oral cavity, a decrease in the body's reactivity, microbial sensitization, and the development of allergic conditions. This pathological process is not a strictly limited pathology but, as a rule, is just one of the manifestations of more serious systemic diseases. The general state of human health, the quality of life, his socio-mental status and even his role in society suffer.Keywords:periodontium, inflammation, platelet autoplasm

scholarly journals The Role of Epigenetics in Periodontal and Systemic Diseases and Smoking: A Systematic Review

2021 ◽  
Vol 11 (11) ◽  
pp. 5269
Author(s):  
Ismael Khouly ◽  
Rosalie Salus Braun ◽  
Michelle Ordway ◽  
Iya Ghassib ◽  
Lena Larsson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dna Methylation ◽  
Web Of Science ◽  
Periodontal Diseases ◽  
Smoking Habit ◽  
Patient Characteristics ◽  
Systemic Diseases ◽  
Inclusion Criteria ◽  
Search Terms

The aims of this systematic review were to identify and synthesize the evidence for an association in DNA methylation/histone modifications between periodontal diseases and systemic diseases/smoking. Electronic database searches using relevant search terms in PubMed, Embase, MEDLINE, CINAHL, Web of Science, Scopus, and SciELO, and manual searches, were independently conducted to identify articles meeting the inclusion criteria. Nine studies of 1482 participants were included. Periodontitis was compared to metabolic disorders, rheumatoid arthritis (RA), cancer, and smokers, as well as healthy controls. Substantial variation regarding the reporting of sample sizes and patient characteristics, statistical analyses, and methodology was found. IL6 and TNF were modified similarly in RA and periodontitis. While TIMP-3 and GSTP-1 were significantly lower in periodontitis patients and controls than in cancer, SOCS-1, RMI2, CDH1, and COX2 were modified similarly in both cancer and periodontitis. While TLR4 in and CXCL8 were affected in periodontitis independent of smoking habit, smoking might change the transcription and methylation states of ECM organization-related genes, which exacerbated the periodontal condition. There was some evidence, albeit inconsistent, for an association between DNA methylation and periodontal diseases and systemic diseases or smokers compared to healthy patients or non-smokers.

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