scholarly journals MODERN SUBMISSION OF FORMATION, COMPOSITION AND ROLE OF ORAL (DENTAL) BIOFILM IN DEVELOPMENT OF PERIODONTAL DISEASES

2020 ◽  
Vol 73 (8) ◽  
pp. 1761-1764
Author(s):  
Maria O. Stetsyk ◽  
Andriy O. Stetsyk ◽  
Natalia I. Zhero ◽  
Eugene Y. Kostenko ◽  
Svetlana B. Kostenko ◽  
...  
Keyword(s):  
Detailed Analysis ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Oral Biofilm ◽  
Dental Biofilm ◽  
Periodontal Tissues ◽  
Current Trends ◽  
Oral Biofilms ◽  
Depth Study

The aim: To investigate current trends in the study of oral biofilm and its control. Materials and methods: A research of 32 literature sources has been made and it has been taken into account that some terminological differences in determining objects of study. Conclusions: Detailed analysis of modern domestic and foreign literature argues the necessity of further in-depth study of oral biofilms. Understanding the ethiological factors and mechanisms of the pathogenesis periodontal tissues inflammatory diseases gives the opportunity to treat targetly by destroying complicated sections of the vital activities and oral biofilm microorganisms relationships.

scholarly journals DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE OF MICROBIAL FLORA IMBALANCE IN GINGIVAL BIOFILM

2020 ◽  
Vol 5 (2) ◽  
pp. 76-82
Author(s):  
G. A. Loban ◽  
T. O. Petrushanko ◽  
V. V. Chereda ◽  
M. O. Faustova ◽  
M. M. Ananieva ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Prognostic Significance ◽  
Fluid Composition ◽  
Dental Tissues ◽  
Periodontal Tissues ◽  
Dmf Index ◽  
Increased Risk ◽  
Hard Dental Tissues

Background. Periodontal tissues inflammatory diseases are widespread among young people. Objective. This study was aimed at elaborating the method to assess risks of periodontal inflammatory diseases and determining its efficacy depending on the state of dental tissues, gum tissues and sex.          Methods. The study included 182 students (93 men, 89 women) aged 19-29: 22 individuals had no lesions of hard dental tissues and no signs of periodontal disease; 51 individuals were found to have DMF index <6; 52 individuals – DMF index ≥6; 57 individuals were diagnosed with chronic catarrhal gingivitis. Primary groups were formed in autumn; re-examination was carried in spring. The research participants were assessed for detection of risks of periodontal inflammatory disease by the method developes by the authors (Patent UA 54041). Results. The study revealed that the risk of development of preiodontitis increases in individuals with high caries and gingivitis intensity. In spring, more individuals suffer from microbial imbalance in in the composition of gingival sulcus fluid and decrease in the mean stability coefficient value that indicates an increased risk of inflammatory periodontal disease development. Women were less likely to experience seasonal dysbiotic changes in the gingival sulcus fluid composition compared with men. Conclusions. The method suggested for assessment of the risk of periodontal inflammatory diseases is of high informativeness. It allows clinicians detecting early pre-nosological signs of oral microbiocenosis imbalance that enhances the effectiveness of early diagnosis of inflammatory periodontal diseases.

Application of Plant-Based Preparations in a Comprehensive Treatment of Inflammatory Periodontal Diseases

2021 ◽  
Vol 6 (5) ◽  
pp. 38-44
Author(s):  
O. D. Saliuk ◽  
◽  
P. H. Gerasimchuk ◽  
L. O. Zaitsev ◽  
I. I. Samoilenko ◽  
...  
Keyword(s):  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
The Body ◽  
Comprehensive Treatment ◽  
Complex Treatment ◽  
Medicinal Products ◽  
Actual Problem ◽  
Periodontal Tissues ◽  
Wide Range ◽  
Anti Inflammatory

In this article the review of foreign and domestic literary sources, which are devoted to the actual problem of modern dentistry – the treatment of inflammatory diseases of periodontal tissues: gingivitis and periodontitis are presented. The complex approach to their treatment involves the appointment of a significant amount of pharmacotherapeutic drugs. Therapeutic failures and iatrogenic complications have led to the fact that today the interests of doctors and population to medicinal products significantly increased. The purpose of the study is to analyze the data of scientific literature on the use of plant-based medicinal products for the treatment of periodontal inflammatory diseases over the past 10 years. Materials and methods. Comprehensive and systematic analysis of literature. Review and discussion. The analysis of information sources on the use of plant-based medicinal products in dentistry both independently and in the composition of medical and prophylactic means has established that the modern assortment of plant-based preparations in the pharmaceutical market of Ukraine to a certain extent is limited. The emergence of new plant-based species that have been tested in conditions of experimental pathology and require an evidence-based clinical base is noted. The composition of plant-based preparations used for the treatment of inflammatory periodontal diseases include vitamins, biologically active substances, glycosides, alkaloids, in connection with a wide range of action: antiseptic, anti-inflammatory, regenerating, hemostatic, antioxidative. The data on plant-based preparations that are most often used such as chamomile extracts, calendula, hypericum, plantain, kalanchoe, aloe, eucalyptus, milfoil, nettle, calamus and plant-based species are summarized. The medicinal agents considered are mainly recommended for local treatment of periodontal diseases in the form of dental care means, mouth rinse, gel, chewing gum, herbal liquer. It is known that the complex treatment of periodontal diseases includes a general influence on the body. The properties of green tea with its wide range of actions are investigated. With antioxidant properties, it can be a healthy alternative for controlling destructive changes in periodontal diseases. Attention is drawn to the proposed unique natural complex “Resverazin” due to a wide range of pharmacological action, low toxicity and relative safety. The drug produces antioxidant, anti-inflammatory, immune stimulating, vasodilative, neuroprotective action. Conclusion. Based on the literature analysis, it can be concluded that the accumulated experimental and clinical data on the therapeutic properties of plants prove perspective of their use in the complex treatment of inflammatory periodontal diseases. Future studies are mandatory for further confirmation of the effectiveness of these medicinal plants

scholarly journals Role of Calprotectin as a Biomarker in Periodontal Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Lili Wei ◽  
Mingwen Liu ◽  
Haofei Xiong
Keyword(s):  
Periodontal Disease ◽  
Calcium Binding ◽  
Alveolar Bone ◽  
Inflammatory Diseases ◽  
Periodontal Tissues ◽  
Adaptive Immune ◽  
S 100 ◽  
And Function ◽  
Plaque Biofilm

Periodontal disease (PD) is a common infectious and inflammatory disease characterised by inflammation of tissues surrounding and supporting the teeth and destruction of the associated alveolar bone, eventually resulting in tooth loss. This disease is caused by periodontopathic bacteria in plaque biofilm and resultant innate and adaptive immune responses in periodontal tissues. Calprotectin (CLP) is a calcium-binding protein of the S-100 protein family and is found to be induced by activated granulocytes, monocytes, and epithelial cells. CLP has been shown to play an important role in numerous inflammatory diseases and disorders. Increasing evidence indicates that CLP is involved in the progression of PD, and its levels may be associated with disease severity and outcome of periodontal treatments. This review will summarise recent studies regarding the presence, regulation, and function of CLP in PD. The findings indicate that CLP may be an effective biomarker for diagnosis and treatment for the PD.

scholarly journals Psychosocial Stress and its Effect on Periodontal Tissues using Malondialdehyde as Oxidative Stress Biomarker

2018 ◽  
Vol 2 (2) ◽  
pp. 34-39
Author(s):  
Anuradha Mokashi ◽  
Keshava Abbayya ◽  
Siddhartha Varma ◽  
Sameer Zope ◽  
Girish Sugarimath ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Psychosocial Stress ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Stress Index ◽  
Pocket Depth ◽  
Cross Sectional ◽  
Periodontal Tissues ◽  
Stress Biomarker ◽  
Oxidative Stress Biomarker

Background: Stress is playing a major role as an aetiologic factor in the initiation of many systemic diseases. Similarly, it is also thought to be an aetiologic factor in the progression of periodontal diseases. Aim: The production of free radical species is associated with various inflammatory diseases and also during stressful conditions. Hence, an effort in the present study is done to correlate psychosocial stress and periodontitis using serum MDA as an oxidative stress biomarker. Materials and Methods: A current cross-sectional study included 201 individuals between 20 to 60 years of age. A periodontal examination included Probing Pocket Depth, CAL, Plaque Index, and Gingival Index. According to CAL individuals were divided into four groups i.e. healthy, slight (CAL = 1-2 mm), moderate (CAL = 3-4 mm) and severe (CAL = ≥5 mm) periodontitis. Psychosocial stress of the individuals was evaluated using occupational stress index. Serum MDA level was evaluated using spectrochromatometer. Results: Patients with stress demonstrated increased levels of MDA along with a higher loss of attachment. Conclusion: The results revealed statistically significant association between psychosocial stress and periodontitis indicating psychosocial stress as a risk factor for developing periodontitis.

scholarly journals SOME ASPECTS OF THE EATIOLOGY OF PARODONTUS DISEASES. (LITERATURE REVIEW)

2018 ◽  
pp. 54-59
Author(s):  
N.N. Saveleva ◽  
I.I. Sokolova ◽  
S.I. German ◽  
T.V. Tomilina
Keyword(s):  
Gastrointestinal Tract ◽  
Periodontal Disease ◽  
Structural Damage ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Pathological Process ◽  
Chronic Obstructive ◽  
Internal Organs ◽  
Periodontal Tissues

The review of the scientific literature is devoted to the topical issues of studying the etiology of periodontal diseases, which are one of the most common and complex pathologies of the maxillofacial region. Analysis of recent studies proves a stable relationship between the development of periodontal diseases and disorders in the immune system, the neurohumoral system, metabolic disorders, genetic predisposition, and so on. The article presents the data obtained in the course of studying the literature on the role of disorders in the functioning of individual organs (gastrointestinal tract, liver, lungs, heart, and urinary system) in the development of chronic periodontal diseases. The article notes that the anatomical and physiological proximity of the periodontal and digestive tract tissues, the generality of innervation and humoral regulation create prerequisites for the involvement of periodontal disease in the pathological process in diseases of the gastrointestinal tract. One of the main etiological factors in the development of inflammatory diseases of the gastrointestinal tract and periodontium is Helicobacter pylori, which is found in the loci of the oral cavity: in the oral and gingival fluid, on the mucous membrane of the tongue and cheeks, and in the periodontal pockets. It is pointed out that the liver also occupies a special place in the development of periodontal diseases, which is explained by the performance of its significant functions for the human body: regulatory, metabolic, antitoxic and other. There is evidence that the pathology of periodontal disease plays a leading role in the structure of dental diseases in patients with chronic obstructive pulmonary diseases, which is clinically manifested by symptoms of generalized periodontitis of the І-ІІ degrees of development and its complications - partial or complete secondary adentia, and with tooth preservation - defects in dental series and violations of occlusion, function, aesthetics. Scientists suggest a general biological mechanism for the development of generalized periodontitis and cardiovascular diseases, linking the development of periodontal diseases in patients with cardiovascular pathology with microcirculatory disorders. The dependence of the severity of inflammatory changes in the periodontal tissues on the disturbances of salt metabolism in urolithiasis is proved. The data obtained indicate that diseases of the internal organs contribute to the structural damage of periodontal tissues and they are a risk factor for periodontal diseases, which necessitate the presence of not only theoretical knowledge and practical skills in dentistry, but also their awareness of the features and clinical manifestations of somatic pathology. An urgent and justified step in the treatment of periodontal diseases is also the involvement in the process of rendering complex dental care to internist doctors capable of quickly and qualitatively assessment the condition of the internal organs and the basic systems of the patient's body.

scholarly journals ORAL CARE AND CHOICE OF MEDICINES FOR TREATING GINGIVITIS AND PERIODONTITIS IN CHILDREN WITH TYPE 1 DIABETES MELLITUS

2020 ◽  
Vol 20 (1) ◽  
pp. 199-204
Author(s):  
I.O. Kuz ◽  
O.V. Sheshukova
Keyword(s):  
Diabetes Mellitus ◽  
Inflammatory Diseases ◽  
Type I Diabetes ◽  
Periodontal Diseases ◽  
Oral Care ◽  
Time Interval ◽  
Type I ◽  
Periodontal Tissues ◽  
Prophylactic Measures ◽  
Dental Appointment

The anatomical and physiological characteristics of a growing organism require a specific approach to the prevention and treatment of periodontal diseases. Not enough attention is paid toward improving the oral health of children suffering from diabetes mellitus, as well as therapeutic and prophylactic measures aimed at preserving teeth and preventing exacerbations of the inflammatory process in periodontal tissues. The results of clinical studies indicate a high prevalence of dental diseases in patients with type I diabetes mellitus; there are not enough reliable results of such indicators depending on the age and duration of this endocrine pathology, diabetic complications, hypoglycemic therapy taking into account metabolic control. Diagnosis of periodontal diseases is complicated by the peculiarities of the child’s psychological perception, caused by age-specific characteristics and the influence of common manifestations of inflammatory diseases. Children of primary school age often demonstrate increased motor activity, a hyperergic reaction even to minor negative feelings, the difficulty of adequate behaviour in an unfamiliar environment and a correct assessment of what is happening, being stressed due to the presence of many phobias associated with doctors and medical manipulations, communicative difficulties caused by staying in the spotlight, meeting new people, talking with adults. Teaching children must necessarily be accompanied by educating parents, since within limited time interval of dental appointment a doctor does not have the opportunity to fully monitor and consolidate the knowledge and skills the child has received, and this responsibility falls on parents. In this case, some attention should be paid to issues of skills, motivation as well as on the importance dental care aspects for the development of the dentofacial system, since in the vast majority of cases, parents are not enough aware on these issues. In addition to educating and fostering the motivation, it is necessary to control the level of knowledge, the frequency and quality of tooth brushing. For young children, it is necessary to do complete cleaning up the chewing group of teeth due to the low level of children’s manual skills.

scholarly journals CHARACTERISTICS OF THE COMPOSITION OF GINGIVAL POCKETS MICRFLORA ISOLATED FROM PATIENTS WITH PURULENT INFLAMMATORY DISEASES IN THE PERIODONTAL TISSUES

2021 ◽  
pp. 20-26
Author(s):  
I. A. Voronkina ◽  
V. F. Dyachenko ◽  
A. M. Maryuschenko ◽  
E. S. Serdechna ◽  
V. G. Rusanova
Keyword(s):  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Disease Incidence ◽  
Specific Weight ◽  
Biochemical Properties ◽  
World Health ◽  
Candida Spp ◽  
Isolation And Identification ◽  
Periodontal Tissues ◽  
Staphylococcus Spp

The problem of the purulent inflammatory disorders of periodontal tissues (PIDPT) at the present time is extremely prevalent. According to the World Health Organization (WHO), around 80% of people suffer from periodontal diseases, and the disease incidence among young people increases significantly and reaches up to 80-95 %. The aim of the present research was to study the composition of microflora of gingival pockets in patients with purulent inflammatory periodontal diseases (PIDPT) in order to establish the specific weight of the determined microbial associations. Materials and methods. Microbiological researches included isolation and identification of bacteria that were present in the gingival pockets of patients with different types of PIDPT. Identification of anaerobic microorganisms and associated microflora was carried out with the help of commonly used classical bacteriological methods, with determination of biochemical properties of the microorganisms cultures using APІ and ANAEROtest 23. Results. There were 192 patients studied in total, all aged older than 20 with diagnoses acute and chronical periodontitis, aggressive periodontitis, hypertrophic pulpitis, granulating periodontitis, parodontopathy, and local periodontitis with a presence of fistula. During the analysis of composition of the microflora isolated from periodontal tissue in patients with PIDPT, the following pathogens were isolated most frequently during the bacteriological research: Streptococcus spp., Staphylococcus spp., Neisseria spp., Stomatococcus spp., and Enterococcus spp. (58%). The quantity of periodontally pathogenic microorganisms was constituted 19,3% from the total quantity of isolated streains (81 isolates). The most numerous group was determined to be the “orange” complex (59,3%) – isolates of Prevotella melaninogenica, Fusobacterium nucleatum, Parvimonas micra. The least numerous was the group of “green” complex - (2,5 %) – Streptococcus mitis. Periodontally pathogenic representatives of microbiota in all cases were isolated as a part of associations with other bacteria. The presented materials signified that the periodontally pathogenic agents of the “red” and “orange” complexes were isolated together with representatives of Streptococcus spp - 33 (56,0 %) associations; Staphylococcus spp - 11(18,6%) – associations. Also in 13 cases (22,1 %) of associations the associated flora was represented by Candida spp. fungi. Conclusions. In course of the research, 4 species of “red” and “orange” complexes were identified, and the quantity of different associations there were present in was significant. There were 22 associations determined. The obtained date concerning microbial associates in the content of gingival pockets in PIDPT show the necessity of individual approach during treatent of this patient group, with taking into account the microbial diversity.

scholarly journals Clinical and immunological studies of periodontal inflammatory complications at orthodontic treatment using fixed appliances

2014 ◽  
Vol 95 (1) ◽  
pp. 80-82
Author(s):  
G R Khaliullina ◽  
S L Blashkova
Keyword(s):  
Immune Response ◽  
Orthodontic Treatment ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Orthodontic Appliances ◽  
Periodontal Inflammation ◽  
Fixed Orthodontic Appliances ◽  
Fixed Appliances ◽  
Orthodontic Devices

The review of clinical and immunologic studies of periodontal inflammatory diseases is presented. At present, the most effective tools for treatment of malocclusions are fixed orthodontic appliances (dental braces), but the use of fixed appliances complicates the oral hygiene, predisposes to periodontal and gum inflammation. The rate of complications diagnosed during orthodontic treatment stays high. The principles of periodontal inflammatory diseases (gingivitis, periodontitis) treatment are closely related with the causes and mechanisms of periodontal inflammation. Patients who receive orthodontic treatment using braces should be treated as a group with a high risk for inflammatory periodontal diseases. The orthodontic devices stimulate the directed reorganization of periodontal structures achieving optimal aesthetic and functional standards. Physiology of periodontium restructuring is largely determined by the local and general health before, during and after the orthodontic treatment. This article surveys the mechanisms of periodontal damage, highlighting the important role of immune response. So far, only anecdotal descriptions of immune response on the stages of orthodontic treatment are published.

scholarly journals PECULIARITIES OF INTERROGATION IN THE INVESTIGATION OF CRIMINAL OFFENSES IN THE FIELD OF REAL ESTATE

2020 ◽  
Vol 1 (4(106)) ◽  
pp. 207-214
Author(s):  
О. В. Коршун
Keyword(s):  
Real Estate ◽  
Objective Assessment ◽  
Criminal Activity ◽  
Criminal Proceedings ◽  
Current Trends ◽  
Criminal Offenses ◽  
Number Of Factors ◽  
Scientific World ◽  
Depth Study

The article considers the concepts, procedural and tactical features of interrogation of different categories of persons during the investigation of criminal offenses in the field of real estate. It is emphasized that interrogation is the most common investigative (search) action in absolute percentage with other procedural actions. During its holding it is possible to establish information about the event of the crime, its circumstances, participants, the role of each, etc. The information received from the subjects of criminal proceedings may cover a significant number of factors that will allow an objective assessment of the situation and used in the evidentiary process, in order to bring the perpetrators to justice. It is established that the issues of interrogation are constantly in the center of close attention of scientists, which is due to the constant improvement of ways of committing crimes and changing the mechanism of criminal activity in general. Practice is forced to respond to various innovations, and representatives of the scientific world are constantly trying to find new ways to solve problems related to the effective conduct of investigative (search) actions. This presupposes the adoption of effective measures in line with current trends and changes in forms of criminal activity, including in the field of employment. It is emphasized that due to the specifics of criminal offenses in the field of real estate, the question of the need for in-depth study of organizational, tactical and procedural aspects of the interrogation of various persons in proceedings of this category is urgent. It is emphasized that the peculiarities of establishing psychological contact and tactics of direct interrogation differ significantly, depending on the procedural status of the interrogated person. If the victim or witness is mostly in contact and prone to communication, a large arsenal of tactics should be used against the suspects, including: presenting evidence; announcement of testimony of other persons; the use of contradictions in the testimony of the same person; creating the impression of awareness of the investigator; suddenness factor, etc. The organizational and tactical features of interrogations in proceedings of this category are determined, the circumstances to be established are outlined and the list of issues that determine the specifics of criminal offenses in the field of real estate is given.

Impact of Hydrodynamics on Oral Biofilm Strength

2009 ◽  
Vol 88 (10) ◽  
pp. 922-926 ◽  
Author(s):  
E. Paramonova ◽  
O.J. Kalmykowa ◽  
H.C. van der Mei ◽  
H.J. Busscher ◽  
P.K. Sharma
Keyword(s):  
Laser Scanning ◽  
Periodontal Diseases ◽  
Single Species ◽  
Laser Scanning Microscopy ◽  
Confocal Laser ◽  
Oral Biofilm ◽  
Actinomyces Naeslundii ◽  
Mechanical Removal ◽  
Hydrodynamic Shear ◽  
Oral Biofilms

Mechanical removal of oral biofilms is ubiquitously accepted as the best way to prevent caries and periodontal diseases. Removal effectiveness strongly depends on biofilm strength. To investigate the influence of hydrodynamics on oral biofilm strength, we grew single- and multi-species biofilms of Streptococcus oralis J22, Actinomyces naeslundii TV14-J1, and full dental plaque at shear rates ranging from 0.1 to 50 1/sec and measured their compressive strength. Subsequently, biofilm architecture was evaluated by confocal laser scanning microscopy. Multi-species biofilms were stronger than single-species biofilms, with strength values ranging from 6 to 51 Pa and from 5 to 17 Pa, respectively. In response to increased hydrodynamic shear, biofilm strength decreased, and architecture changed from uniform carpet-like to more “fluffy” with higher thickness. S. oralis biofilms grown under variable shear of 7 and 50 1/sec possessed properties intermediate of those measured at the respective single shears.

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