scholarly journals Revisiting the history of Takayasu's disease studies and surgical techniques used in its treatment

2020 ◽  
pp. 143-160
Author(s):  
A. E. Zotikov ◽  
V. A. Kulbak ◽  
A. V. Abrosimov ◽  
D. A. Lavrentyev
Keyword(s):  
Thoracic Aorta ◽  
Systemic Disease ◽  
Surgical Techniques ◽  
Clinical Manifestations ◽  
Coarctation Of Aorta ◽  
Historical Aspect ◽  
Takayasu's Disease ◽  
Visceral Arteries ◽  
Takayasu’S Disease ◽  
History Of

Nonspecific aortoarteritis is a systemic disease, which has been referred to the group of vasculitis affecting elastic and muscular arteries oflarge and medium calibre with the inflammatory processlocalized in the media and adventitia. The article presents the history of development of ideas about clinical manifestations, morphological changes and the course of the disease from 1761 to the present day, the timeline of medical advances in this disease studies. The genuine interest in nonspecific aortoarteritis arose at the beginning of thelast century, when the Japanese ophthalmologist Mikito Takayasu reported unusual changes in the retinal vessels of a 21-year-old Japanese girl suffering from recurrent bouts of syncope. The first publications dealt with clinical manifestations in the patients, who had only brachiocephalic arterial involvement. In the early 60s, it was found that nonspecific aortoarteritis (Takayasu's disease) can affect not only the branches of the aortic arch, but also the thoracic aorta, renal and visceral arteries. It was the mosaic clinical manifestations in patients with various forms of Takayasu's disease that caused the presentation of the disease in theliterature until the mid-1970s under various terms such as “pulseless disease”, “arteritis of young women”, “brachiocephalic arteritis”, “atypical coarctation of aorta”, “Martorell's syndrome”, “syndrome of obliteration of the supra-aortic trunks”, “panaortitis” or “panarteritis”, “aortitis syndrome”, “mid-aortic syndrome”, “occlusive thromboarteriopathy”. The review details the epidemiology and prevalence of this disease. Views not only on the etiology and pathogenesis, but also on the methods of treating this disease have changed since M. Takayasu's publication in 1908. Much attention is paid to the historical aspect of the first surgical procedures. Starting in 1951, the surgical method has firmly taken the lead in the treatment of stenosis of the carotid arteries, thoracic aorta, renal and visceral arteries. Surgical concepts changed, but the literature data indicate the sustainability of the basic principle of treatment: combination of surgical interventions and various antiinflammatory therapy regimens.

scholarly journals Oral Manifestations of Celiac Disease and Wheat Allergy: Report of Three Cases and Review of Literature

2018 ◽  
pp. 33-45
Author(s):  
Yadira V. Boza Oreamuno DDS, MSc ◽  
María F. Rugama Flores BSND
Keyword(s):  
Celiac Disease ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Abdominal Distension ◽  
Clinical History ◽  
Recurrent Abdominal Pain ◽  
Oral Manifestations ◽  
Wheat Allergy ◽  
Immune Mediated ◽  
History Of

Celiac Disease (CD) is an immune-mediated systemic disease, caused by gluten and related prolamins, in genetically susceptible individuals. It is characterized by gluten-dependent clinical manifestations, CD-specific antibodies, HLA DQ2 or DQ8 haplotypes, and enteropathy. Most patients are asymptomatic or with mild manifestations. It mainly affects the gastrointestinal system causing symptoms and signs such as diarrhea, recurrent abdominal pain and abdominal distension; also extradigestive manifestations. Patients with CD may have oral manifestations that include recurrent aphthous stomatitis (RAS), enamel hypoplasia, atrophic glossitis, among others. The diagnosis of CD is based on clinical history, serology, endoscopy and histology. There are other entities that should be differentiated from CD, such as non-celiac gluten sensitivity and wheat allergy. The aim of this study is to present three patients with a history of RAS and other clinical manifestations associated with the early diagnosis of CD and food allergy.

scholarly journals Natural history of aortoarteritis (Takayasu's disease).

Circulation ◽  
1989 ◽  
Vol 80 (3) ◽  
pp. 429-437 ◽  
Author(s):  
R Subramanyan ◽  
J Joy ◽  
K G Balakrishnan
Keyword(s):  
Natural History ◽  
Takayasu's Disease ◽  
Takayasu’S Disease ◽  
History Of

scholarly journals Compression of the сeliac trunk syndrome. History of the problem

2020 ◽  
Vol 11 (5) ◽  
pp. 51-56
Author(s):  
Zarina M. Khamid ◽  
Dmitrij I. Vasilevsky ◽  
Anatoly M. Ignashov ◽  
Andrey Yu. Korolkov ◽  
Stanislav G. Balandov
Keyword(s):  
Abdominal Pain ◽  
English Language ◽  
Surgical Techniques ◽  
Clinical Manifestations ◽  
Significant Development ◽  
Anatomical Features ◽  
Ischemic Disease ◽  
Compression Syndrome ◽  
History Of ◽  
Dunbar Syndrome

The article presents the main stages of the development of ideas about a fairly rare pathology in clinical practice the syndrome of compression of the ventral trunk. Until the mid-nineteenth century, reports of the clinical picture of chronic abdominal ischemia were more descriptive. Serial pathoanatomic studies, comparison of anatomical features revealed at autopsy with clinical manifestations accompanying these changes, contributed to the isolation of chronic ischemic disease of the digestive system in a separate nosological form. The discovery of angiography contributed to the significant development of vascular surgery and the isolation of the ventral trunk compression syndrome as an independent disease, since it allowed for a lifetime comparison of the detected changes in blood vessels with the clinical manifestations of the disease. The term ventral trunk compression syndrome was first introduced by P. Harjola when describing a case of abdominal pain in a patient with compression of the ventral trunk by the neuroganglionic tissue of the ventral plexus. Later, J. Dunbar confirmed the Association of clinical manifestations of chronic abdominal pain with compression of the ventral trunk by the median arched ligament of the diaphragm. In English-language literature, the disease was named Dunbar syndrome. The effectiveness of eliminating the symptoms of this disease by surgical dissection of compression structures has been proven. Further study of this problem developed in parallel with the development of surgery in General in accordance with the emergence and introduction of new surgical technologies. The purpose of numerous studies was to study the etiopathogenetic mechanisms of the occurrence of a variety of clinical manifestations of this syndrome and improve the results of its treatment by improving known surgical techniques and introducing new ones.

scholarly journals Indications for Peripartum Aortic Pressure Monitoring in Takayasu's Disease. A Patient with Past History of Intrapartum Cerebral Hemorrhage.

1998 ◽  
Vol 39 (2) ◽  
pp. 255-260 ◽  
Author(s):  
Nobuyoshi TOMIOKA ◽  
Kunihiko HIROSE ◽  
Emiko ABE ◽  
Norio MIYAMOTO ◽  
Kazukuni ARAKI ◽  
...  
Keyword(s):  
Cerebral Hemorrhage ◽  
Past History ◽  
Aortic Pressure ◽  
Pressure Monitoring ◽  
Takayasu's Disease ◽  
Takayasu’S Disease ◽  
History Of

Etiology and clinical features of epididymo-orchitis: A single-center study in Tehran, Iran

2020 ◽  
Vol 20 ◽  
Author(s):  
Sara Abolghasemi ◽  
Mohammad Alizadeh ◽  
Ali Hashemi ◽  
Shabnam Tehrani
Keyword(s):  
Chlamydia Trachomatis ◽  
Clinical Symptoms ◽  
Urine Culture ◽  
Clinical Manifestations ◽  
Urinary Frequency ◽  
Serological Tests ◽  
Duration Of Symptoms ◽  
Two Samples ◽  
History Of ◽  
Tract Infections

Introduction: Epididymo-orchitis is a common urological disease among men. Little is known about the clinical and epidemiological aspects of the disease in Iran. Thus, the present study was aimed to investigate the etiology, clinical sequelae and risk factors of patients with epididymo-orchitis in Tehran, Iran. Materials and Methods: Patients presenting with epididymo-orchitis were prospectively analyzed in order to study the etiology and pattern of the disease. Bacteriological, molecular and serological tests were undertaken to look for Chlamydia trachomatis, Neisseria gonorrhoeae, Brucella spp., Mycoplasma spp, and other bacteria. Results: Fifty patients with epididymo-orchitis were evaluated according to their clinical symptoms, duration of symptoms, physical examination, and laboratory studies. The mean age of the patients was 53 years. Fever, dysuria, pain in the flanks, urinary frequency and discharges occurred in 58.0%, 50.0%, 50.0%, 28.0% and 6.0%, respectively. Bacterial pathogen was identified in 26% (13/50) of patients by urine culture. Escherichia coli was the etiological agent in 11/13 patients (84.6%). Two out of 50 patients (4.0%) were also positive for Chlamydia trachomatis. Two samples were serologically positive for Brucella spp. High Mean age, fever, urinary frequency, history of the underlying disease and history of urinary tract infections were found to have a significant association with the positive bacteriologic urine culture (P<0.05). Conclusions: The most common clinical manifestations were fever, dysuria, and abdominal pain. E. coli and C. trachomatis were the major causative agents. Use of a set of diagnostic approaches including clinical symptoms, urine culture and more precise techniques such as PCR should be taken into consideration for the definitive diagnosis.

scholarly journals Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 271
Author(s):  
Saverio Capodiferro ◽  
Luisa Limongelli ◽  
Gianfranco Favia
Keyword(s):  
Early Diagnosis ◽  
Oral Cavity ◽  
Head And Neck ◽  
Clinical Outcomes ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Systemic Diseases ◽  
Special Issue ◽  
Hard Tissues ◽  
Current Special Issue

Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

scholarly journals The Main Challenges in Systemic Lupus Erythematosus: Where Do We Stand?

2021 ◽  
Vol 10 (2) ◽  
pp. 243
Author(s):  
Matteo Piga ◽  
Laurent Arnaud
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Systemic Disease ◽  
Unmet Need ◽  
Clinical Manifestations ◽  
New Drugs ◽  
Systemic Lupus ◽  
Major Step ◽  
Damage Accrual

Systemic lupus erythematosus (SLE) is an immune-mediated multi-systemic disease characterized by a wide variability of clinical manifestations and a course frequently subject to unpredictable flares. Despite significant advances in the understanding of the pathophysiology and optimization of medical care, patients with SLE still have significant mortality and carry a risk of progressive organ damage accrual and reduced health-related quality of life. New tools allow earlier classification of SLE, whereas tailored early intervention and treatment strategies targeted to clinical remission or low disease activity could offer the opportunity to reduce damage, thus improving long-term outcomes. Nevertheless, the early diagnosis of SLE is still an unmet need for many patients. Further disentangling the SLE susceptibility and complex pathogenesis will allow to identify more accurate biomarkers and implement new ways to measure disease activity. This could represent a major step forward to find new trials modalities for developing new drugs, optimizing the use of currently available therapeutics and minimizing glucocorticoids. Preventing and treating comorbidities in SLE, improving the management of hard-to-treat manifestations including management of SLE during pregnancy are among the remaining major unmet needs. This review provides insights and a research agenda for the main challenges in SLE.

The physiopathology of spontaneous hemorrhagic stroke: a systematic review

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Alcivan Batista de Morais Filho ◽  
Thiago Luis de Holanda Rego ◽  
Letícia de Lima Mendonça ◽  
Sulyanne Saraiva de Almeida ◽  
Mariana Lima da Nóbrega ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Ischemic Stroke ◽  
Subarachnoid Hemorrhage ◽  
Natural History ◽  
Hemorrhagic Stroke ◽  
Recent Literature ◽  
Clinical Manifestations ◽  
The Road ◽  
History Of

Abstract Hemorrhagic stroke (HS) is a major cause of death and disability worldwide, despite being less common, it presents more aggressively and leads to more severe sequelae than ischemic stroke. There are two types of HS: Intracerebral Hemorrhage (ICH) and Subarachnoid Hemorrhage (SAH), differing not only in the site of bleeding, but also in the mechanisms responsible for acute and subacute symptoms. This is a systematic review of databases in search of works of the last five years relating to the comprehension of both kinds of HS. Sixty two articles composed the direct findings of the recent literature and were further characterized to construct the pathophysiology in the order of events. The road to the understanding of the spontaneous HS pathophysiology is far from complete. Our findings show specific and individual results relating to the natural history of the disease of ICH and SAH, presenting common and different risk factors, distinct and similar clinical manifestations at onset or later days to weeks, and possible complications for both.

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