scholarly journals Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 271
Author(s):  
Saverio Capodiferro ◽  
Luisa Limongelli ◽  
Gianfranco Favia

Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

Author(s):  
Mohd Rizwan Khan

Background: The oral cavity is a mirror of the body, entry point to food, antigens, and microorganisms. Oral cavity with mastication and speech, also have a role play in immunological defense. The Oral mucous membrane is in link with skin, oropharynx, and nasopharynx. The oral cavity and anterior two-thirds of the tongue are formed by the ectoderm and that is why from a dermatologist's viewpoint, an oral opening is especially imperative and involved in a range of systemic and skin disease, also affect teeth and gums. The body's natural protection is in good quality oral care. Oral problems when associated with skin conditions require oral care as it affects the quality of life and enable dermatologist and dentist in the identification and diagnosing of systemic disease. Oral illness can bring into being from infection, inflammation or neoplastic, immunological, benign, or malignant. Results: The oral cavity is a mirror to a variety of systemic and cutaneous diseases. Interpretation of the symptom and signs of systemic diseases help early diagnosis. However, while not correct oral hygiene, microorganisms will reach levels that may result in oral infections and decay. The health status of our oral cavity can give us a strong signal of the health of our bodies. It proceeds as a premature warning system. That's why the oral cavity should be examined in one piece from the buccal mucosa to the oropharynx. Conclusion: The mouth is a straightforwardly available window of the body. In contemplation with development, composition, and utility oral cavity is only one of its kind. It is a two-way road as systemic skin disease has oral manifestation. Interpretation of the symptom and signs help in identification and early diagnosis of systemic diseases. Oral illness can bring into being from infection, inflammation or neoplastic, immunological, benign, or malignant. That's why the oral cavity should be examined in one piece from buccal mucosa, lips, tongue, gum, teeth, palate to the oropharynx. Knowledge of systemic diseases is vital in day to day clinical practice, often oral manifestation is the most significant or first sign of systemic illness. So dermatologists and dental surgeons are conscious of oral complaints and their association with systemic disease.


2020 ◽  
Vol 9 (10) ◽  
pp. 3156
Author(s):  
Gerhard Schmalz ◽  
Dirk Ziebolz

With an enormous prevalence worldwide, diseases of the oral cavity and respective tissues are a highly relevant global health issue [...]


2009 ◽  
Vol 11 (5) ◽  
pp. 395-407 ◽  
Author(s):  
Marc Kent

Practical relevance A number of systemic diseases are associated with neurological deficits. Most systemic diseases that impact on the nervous system result in multifocal neurological signs; however, isolated deficits can also be observed. This article reviews the clinical signs, pathophysiology, diagnosis, treatment and prognosis of four important systemic diseases with neurological consequences: feline infectious peritonitis, toxoplasmosis, hypertension and hepatic encephalopathy. Clinical challenges Early recognition of systemic signs of illness in conjunction with neurological deficits will allow for prompt diagnosis and treatment. While neurological examination of the feline patient can undoubtedly be challenging, hopefully the accompanying articles in this special issue will enable the clinician to approach these cases with more confidence. Evidence base The veterinary literature contains numerous reports detailing the impact of systemic disease on the nervous system. Unfortunately, very few references provide detailed descriptions of large cohorts of affected cats. This review summarises the literature underpinning the four key diseases under discussion.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
A. L. Hamdan ◽  
D. Sarieddine

Rheumatoid arthritis is a destructive autoimmune disease that affects 3% of the adult population. It is characterized by the formation of both articular and extra-articular lesions with predilection for small joints. There are ubiquitous reports on the head and neck manifestations of RA with emphasis on the larynx. The laryngeal presenting features of this systemic disease may mimic a plethora of medical conditions, inflammatory and neoplastic. The main phonatory and respiratory symptoms are often subtle and misleading. This paper represents a literature review of the laryngeal manifestations of RA with emphasis on the clinical symptoms, laryngeal findings, diagnosis, and treatment. An early diagnosis of laryngeal involvement may prevent drastic complications.


Dental Update ◽  
2019 ◽  
Vol 46 (10) ◽  
pp. 914-917
Author(s):  
Aaron Lopez-Lago ◽  
Mahbuba Tasnima Choudhury ◽  
Praveen Sharma

That the mouth and the body are not disconnected should come as no surprise. In this article, the links between periodontal and systemic health will be reviewed by investigating these in both directions, starting with the more familiar effects of systemic conditions on periodontal health and progressing to the emerging effects of periodontal health on systemic health. Where suitable, tips will be provided for practitioners caring for patients with periodontitis and systemic diseases. CPD/Clinical Relevance: In recognition of the important role that the oral cavity plays in the body and the important role that oral healthcare providers play in the management of the general wellbeing of patients, this article highlights the link between periodontitis and systemic heath. This allows practitioners to care more holistically for their patients.


2019 ◽  
pp. 11-16
Author(s):  
V. V. Gaynitdinova ◽  
A. A. Burdunina ◽  
S. N. Avdeyev

Although there is now much evidence that COPD is a more complex systemic disease than airway and lung disease, a comprehensive approach to early diagnosis and more accurate assessment of the disease is far from complete. The most common co-morbidities with COPD are cardiovascular disease, diabetes mellitus, osteoporosis, depression, anemia, etc. The problem of diagnosis and treatment of COPD patients with osteoporosis is currently topical and insufficiently studied. In this review the peculiarities of osteoporosis in COPD are considered: its prevalence, the influence of the severity of bronchial obstruction on the bone mineral density (BMD), clinical manifestations (frequency of vertebral body compression fractures (VBCF) and hip fractures), the influence of risk factors (glucocorticosteroids, low body weight, vitamin D deficiency, smoking, impaired lung ventilation, sedentary lifestyle, etc.) on the development of osteoporosis. Data of researches on studying bone formation markers and bone resorption in patients with COPD are given. Full understanding of the mechanisms of development, early diagnosis of osteoporosis in COPD patients will allow to choose the most effective therapeutic tactics, which will correspond to the modern concept of personalized medicine.


This chapter covers a disparate group of conditions that may present within the oral cavity, primarily affecting the oral mucosa. Many are common, and will be seen regularly in clinical practice. Others are rare, but awareness is required in order to be able to identify these cases. Some are manifestations of systemic disease, such as gastrointestinal or dermatological disorders; others are localized to the head and neck region. An overview of the common infective conditions of the mouth is included. Finally, the many conditions resulting in facial pain are considered. The aetiology, presentation and management of these conditions is explored.


2002 ◽  
Vol 59 (6) ◽  
pp. 669-673 ◽  
Author(s):  
Mario Vicente-Barrero ◽  
Ines García-Castro ◽  
Milan Knezevic ◽  
Jose Castellano-Reyes ◽  
Francisco García-Jimenez ◽  
...  

Non-Hodgkin lymphomas (NHL) often show up in an extranodal pattern, especially in the head and neck. Intraoral locations are much less frequent, particularly when they are single. This, in turn, can lead to a prolonged diagnosis and even to inadequate treatment. Different patients with initial extranodal location of NHL which were not previously diagnosed and in which it was manifested only intraoraly are presented in this paper. These cases are presented together with the additional examinations used for the early diagnosis and with the corresponding clinical pictures, as well as with the overview of other cases from the available literature.


Introduction: Clinical radiotherapy is one of the most important techniques for the treatment of malignant lesions in head and neck; however, exposure to ionizing radiation may lead to both systemic and local complications, immediately and after this treatment, where the main issue is the xerostomia and its consequent oral mucositis. Regarding late complications produced by radiation, decay of radiation and osteoradionecrosis, both dosedependent lesions, showed a high level of incidence in recent decades and it would be difficult to manage, although patients referred after treatment’s completion and under the influence of local factors. Methodology: Then, This study evaluated the effect of ionizing radiation from gamma source onto samples of enamel, root dentin and jawbone samples undergone to the same absorbed dose / dose rate that those in patients with head and neck cancer. The non-irradiated and irradiated samples were analyzed by microhardness surface analysis; scanning electron microscopy (SEM) and Fourier transform infrared spectrometry (FTIR). Results and discussion: Microhardness data were analyzed statistically with a confidence level of 95% (p value <0.05%), using parametric Student’s t-test for related averages and ANOVA statistical test, finding a statistically significant result (p = 0.00) to all four groups samples. Conclusion: It was observed a high deleterious and statistical significant effect of gamma radiation on hard tissues from oral cavity, regarding to physical, compositional and morphological properties.


2006 ◽  
Vol 121 (4) ◽  
pp. 362-368 ◽  
Author(s):  
K Menon ◽  
C Bem ◽  
D Gouldesbrough ◽  
D R Strachan

Aims: To analyse the epidemiology, presentation and diagnosis of head and neck tuberculosis (TB).Methods: We conducted a 10-year retrospective study of all cases of tuberculosis of the head and neck region occurring in Bradford, UK.Results: Of a total of 1315 cases of TB, 128 presented with head and neck TB (12 per cent of which (15/128) were in children). Cervical lymph nodes were most commonly involved (87 per cent, 111/128), other sites being: salivary glands (five cases); larynx, oral cavity, eyes and ears (two cases each); and skin, thyroid, nasopharynx and retropharyngeal space (one case each). Patients' ethnic origins were Asian (89 per cent, 114/128), Caucasian (10 per cent, 13/128) and African (one case). Only 26 per cent (33/128) had constitutional symptoms, and 20 per cent (25/128) had a coexistent site of TB. Only 39 per cent (40/105) of surgical specimens were sent for culture.Conclusions: Isolated head and neck TB is not uncommon. Atypical presentations render diagnosis challenging, so awareness aids early diagnosis. Mycobacterial cultures should be performed, where possible, for diagnosis.


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