scholarly journals Effect of Sorafenib on Liver Biochemistry Prior to Vitamin B17 Coadministration in Ehrlich Ascites Carcinoma Mice Model: Preliminary Phase Study

2021 ◽  
Vol 17 (1) ◽  
pp. 40-49
Author(s):  
Hebatalla M. Nasser ◽  
Sabry Ali El-Naggar ◽  
Mohammed El-Sayed Rizk El-Sayed Rizk ◽  
Alaa Elmetwalli ◽  
Afrah Fatthi Salama
Keyword(s):  
Ehrlich Ascites Carcinoma ◽  
Mice Model ◽  
Phase Study ◽  
Ehrlich Ascites ◽  
Preliminary Phase

scholarly journals Subcutaneous Ehrlich Ascites Carcinoma mice model for studying cancer-induced cardiomyopathy

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Sneha Mishra ◽  
Ankit Kumar Tamta ◽  
Mohsen Sarikhani ◽  
Perumal Arumugam Desingu ◽  
Shruti M. Kizkekra ◽  
...  
Keyword(s):  
Ehrlich Ascites Carcinoma ◽  
Mice Model ◽  
Ehrlich Ascites

Antitumour and Antioxidant Activity of Some Red Sea Seaweeds in Ehrlich Ascites Carcinoma in vivo

2011 ◽  
Vol 66 (7-8) ◽  
pp. 367-376 ◽  
Author(s):  
Hanaa H. Ahmed ◽  
Muhammad M. Hegazi ◽  
Howaida I. Abd-Allac ◽  
Emad F. Eskander ◽  
Mona S. Ellithey
Keyword(s):  
Red Sea ◽  
Antioxidant Activities ◽  
Ehrlich Ascites Carcinoma ◽  
Tumour Marker ◽  
Mice Model ◽  
Ehrlich Ascites ◽  
Ehrlich Ascites Tumour ◽  
Total Antioxidant ◽  
Algal Extracts

1The antitumour activities of extracts from the Red Sea seaweeds Jania rubens, Sargassum subrepandum, and Ulva lactuca were investigated in an in vivo mice model based on intramuscular injection of Ehrlich ascites tumour cells. In parallel, antioxidant activities were measured. Tumour marker levels, liver biochemical parameters, and hepatic oxidant/antioxidant status were measured to prove the anticancer and antioxidant nature of the algal extracts. Significant decreases in carcinoembryonic antigen (CEA) and α-fetoprotein (AFP) levels, activities of liver enzymes, levels of nitric oxide (NO) and malondialdehyde (MDA), and an increase in total antioxidant capacity (TAC) were recorded in groups treated with the algal extracts. Jania rubens was selected for phytochemical screening of its phytoconstituents. In addition, carotenoids, halides, minerals, lipoidal matters, proteins, and carbohydrates were studied. Furthermore, 7-oxo-cholest-5(6)-en-3-ol () and cholesterol (2) were isolated from the dichloromethane fraction.

Trichosanthes dioica seed lectin inhibits Ehrlich ascites carcinoma cells growth in vivo in mice by inducing G 0 /G 1 cell cycle arrest

2021 ◽  
Author(s):  
Shaikh Shohidul Islam ◽  
Md. Rezaul Karim ◽  
A. K. M. Asaduzzaman ◽  
A. H. M. Khurshid Alam ◽  
Zahid Hayat Mahmud ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Ehrlich Ascites Carcinoma ◽  
Carcinoma Cells ◽  
Cycle Arrest ◽  
Ehrlich Ascites ◽  
Trichosanthes Dioica

Antioxidant, cytotoxic and apoptotic potentials of seeds of Momordica subangulata subsp. renigera inhibit the growth of Ehrlich ascites carcinoma in mice

2019 ◽  
Vol 13 (4) ◽  
pp. 3049-3059
Author(s):  
Polash Chandra Karmakar ◽  
Rumana Yesmin ◽  
Hanif Ali ◽  
M. Rowshanul Habib ◽  
Dhirendra Nath Barman ◽  
...  
Keyword(s):  
Ehrlich Ascites Carcinoma ◽  
Ehrlich Ascites

Tumor cell metabolism in vitro: a study of incubation media

1970 ◽  
Vol 48 (4) ◽  
pp. 517-519 ◽  
Author(s):  
I. C. Caldwell ◽  
Marianne F. Chan
Keyword(s):  
Nucleic Acid ◽  
Structural Integrity ◽  
Cell Metabolism ◽  
Ehrlich Ascites Carcinoma ◽  
Leukemic Cells ◽  
Prolonged Incubation ◽  
Ehrlich Ascites ◽  
Eac Cells ◽  
Rna And Dna

A number of incubation media which have been used in studies of the metabolism of Ehrlich ascites carcinoma (EAC) cells in vitro have been examined with respect to their abilities to support the incorporation of radioactive precursors into nucleotides and nucleic acids, and to maintain the structural integrity and tumor-inducing abilities of EAC cells. Cells incubated in the chemically-defined "Fischer's medium for leukemic cells of mice" were able to produce lethal tumors in mice after more than 16 h of incubation, maintained their structural integrity on prolonged incubation, and catalyzed high rates of incorporation of exogenously added substrates into nucleotides, RNA, and DNA. However, cells incubated in balanced salts solutions supplemented with glucose had these characteristics: (a) were unable to produce lethal tumors after 4 h of incubation, (b) released large amounts of nucleotide, nucleic acid, and protein material into the medium after less than 2 h of incubation, and (c) catalyzed the incorporation of radioactive precursors into nucleotides and RNA at much lower rates than did cells incubated in Fischer's medium, and were virtually unable to catalyze the incorporation of adenine-14C into DNA.

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