Relationship of Helicobacter Pylori Infection with Different Digestive System Malignant Tumors

2005 ◽  
Vol 35 (2) ◽  
pp. 255-266
Author(s):  
Hanan Shatat ◽  
Mona Hashish ◽  
Heba Selim
Keyword(s):  
Helicobacter Pylori ◽  
Digestive System ◽  
Malignant Tumors ◽  
Helicobacter Pylori Infection ◽  
Relationship Of

scholarly journals Helicobacter pylori in the clinic of internal medicine

2021 ◽  
Vol 2021 (1) ◽  
pp. 17-21
Author(s):  
T.D. Zvyagintseva ◽  
◽  
Ya.K. Gamanenko ◽  
Keyword(s):  
Internal Medicine ◽  
Diabetes Mellitus ◽  
Multiple Sclerosis ◽  
Metabolic Syndrome ◽  
Helicobacter Pylori ◽  
Cardiovascular Diseases ◽  
Helicobacter Pylori Infection ◽  
Relationship Of

The article is devoted to the analysis of the literature on the problem of the possible relationship of Helicobacter pylori in the pathogenesis of various extragastric pathologies - diabetes mellitus, metabolic syndrome, cardiovascular diseases and multiple sclerosis. It is possible that Helicobacter pylori infection plays an independent role in the pathogenesis of these diseases.

scholarly journals Correlations Between the Density of Tryptase Positive Mast Cells (DMCT) and that of New Blood Vessels (CD105+) in Patients with Gastric Cancer

2016 ◽  
Vol 54 (2) ◽  
pp. 113-120 ◽  
Author(s):  
Gianina Viorica Micu ◽  
Florica Stăniceanu ◽  
Liana Cătălina Sticlaru ◽  
Cristiana Gabriela Popp ◽  
Alexandra Eugenia Bastian ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Mast Cells ◽  
Blood Vessels ◽  
Malignant Tumors ◽  
Helicobacter Pylori Infection ◽  
Tumor Spread ◽  
Mast Cell Density ◽  
Gastric Neoplasia ◽  
Distant Tumor

Abstract Mast cells proteases, tryptase and chymase are directly involved in the growth and progression of solid tumors due to their important role in tumor angiogenesis. We examined the density of tryptase positive mast cells and the mean density of new blood vessels in gastric malignant tumors of patients with and without Helicobacter pylori infection, using immunohistochemical staining for tryptase (for mast cells) and CD 105 (for new vessels). Tryptase and CD 105 expression was detected in gastrectomy specimens. In this study, mast cell density correlates with angiogenesis and the growth and progression of gastric cancer. It also shows that the participation of Helicobacter pylori infection in the growth and progress of gastric neoplasia is due to an increase of peritumoral angiogenesis, with subsequent local and distant tumor spread and perivascular growth, but without perineural and nodal involvement.

scholarly journals Relationship of Helicobacter pylori Infection to Arterial Stiffness in Japanese Subjects

2005 ◽  
Vol 28 (4) ◽  
pp. 283-292 ◽  
Author(s):  
Yasuaki SAIJO ◽  
Megumi UTSUGI ◽  
Eiji YOSHIOKA ◽  
Naoko HORIKAWA ◽  
Tetsuro SATO ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Arterial Stiffness ◽  
Helicobacter Pylori Infection ◽  
Relationship Of ◽  
Japanese Subjects

scholarly journals Sex differences in the relationship among alcohol, smoking, and Helicobacter pylori infection in asymptomatic individuals

2020 ◽  
Vol 48 (5) ◽  
pp. 030006052092603
Author(s):  
Wenzhi Wu ◽  
Marcis Leja ◽  
Vladislav Tsukanov ◽  
Zarrin Basharat ◽  
Dong Hua ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Alcohol Consumption ◽  
Logistic Regression Analysis ◽  
Helicobacter Pylori Infection ◽  
Multivariable Logistic Regression Analysis ◽  
H Pylori ◽  
Relationship Of ◽  
The Relationship

Objective We aimed to investigate the relationship of Helicobacter pylori infection with alcohol and smoking. Methods We conducted a cross-sectional study among participants who underwent health check-ups for H. pylori infection between January 2013 and March 2017. We subsequently investigated the relationship of H. pylori infection with alcohol and smoking. Results A total of 7169 participants were enrolled in this study. The overall prevalence of H. pylori infection was 55.2%. Participants with H. pylori infection were more likely to be older than those without H. pylori infection. For male participants with H. pylori infection, multivariable logistic regression analysis indicated that both smoking (odds ratio (OR): 1.61; 95% confidence interval (CI): 1.41–1.83) and alcohol consumption (OR: 1.30; 95% CI: 1.10–1.52) were independently positively associated with H. pylori infection. For female participants, multivariable logistic regression analysis indicated that both smoking (OR: 0.03; 95% CI: 0.02–0.07) and alcohol consumption (OR: 0.20; 95% CI: 0.12–0.33) were inversely significantly associated with H. pylori infection after adjustment for age. Conclusions Smoking and alcohol consumption were risk factors for male participants but these were protective factors for female individuals with H. pylori infection.

scholarly journals Relationship of Halitosis with Gastric Helicobacter Pylori Infection

2021 ◽  
Vol 15 (7) ◽  
pp. 2285-2288
Author(s):  
Rakhshinda Jabeen ◽  
Ajmaal Jami ◽  
Aiman Shahab ◽  
Armash Shahab
Keyword(s):  
Helicobacter Pylori ◽  
Epigastric Pain ◽  
Human Condition ◽  
Helicobacter Pylori Infection ◽  
University Hospital ◽  
Clear Correlation ◽  
P Value ◽  
Pathophysiological Mechanism ◽  
H Pylori ◽  
Relationship Of

Background: Halitosis is a common human condition; however, the pathophysiological mechanism of halitosis is still unclear. Halitosis is mostly attributed with oral pathological conditions, in addition, halitosis resulting from gastrointestinal disorders is not rare either. Halitosis is often reported with symptoms related to Helicobacter pylori infection, epigastric pain and gastroesophageal reflux disease. Objective: Halitosis can stem from a number of gastric conditions and one of the most common causes of halitosis include the presence of a gastric infection with Helicobacter pylori. This study was conducted to evaluate the incidence ofhalitosis in patients presenting with Helicobacter pylori infection and epigastric pain. Additionally, to review whether there is a correlation between H pylori infection and halitosis; moreover, to determine whether halitosis is a valid indication for H pylori infection. Methods and Materials: This case control, comparative study was done at Medicine department of Isra University hospital and Civil hospital, Karachi during the period of January 2019 to December 2019. Participants were enrolled only after taking verbal and signed consent. Prior permission from the hospital management was taken as well. Result: Halitosis and H pylori are statistically significant with p value of 0.026. There was a clear correlation between halitosis and H pylori infection, and it may be a common contributor to halitosis.

scholarly journals Relationship of interleukin-1B gene promoter region polymorphism with Helicobacter pylori infection and gastritis

2015 ◽  
Vol 9 (10) ◽  
pp. 1108-1116 ◽  
Author(s):  
Ivy Bastos Ramis ◽  
Júlia Silveira Vianna ◽  
Priscila Cristina Bartolomeu Halicki ◽  
Caroline Lara ◽  
Thássia Fernanda Tadiotto ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Promoter Region ◽  
Gene Promoter ◽  
Helicobacter Pylori Infection ◽  
Caga Gene ◽  
Gastric Diseases ◽  
Ulcer Disease ◽  
Increased Risk ◽  
H Pylori ◽  
Relationship Of

Introduction: Helicobacter pylori infection is associated with gastritis, peptic ulcer disease and gastric carcinoma. The severity of damage is determined by the interplay between environmental/behavioral factors, bacterial pathogenicity genes and host genetic polymorphisms that can influence the secretion levels of inflammatory cytokines. Accordingly, this study aimed to identify polymorphisms in the IL-1B and IL-1RN genes and their associations with H. pylori infection, cagA gene of H. pylori, and gastroduodenal diseases. Methodology: Gastric biopsy samples from 151 patients infected with H. pylori and 76 uninfected individuals were analyzed. H. pylori infection was diagnosed by histology and PCR. Polymorphisms at positions -511, -31 and +3954 of the IL-1B gene were detected by PCR-RFLP, and an analysis of the VNTR polymorphism of the IL-1RN gene was performed by PCR. Results: It was observed that the presence of the T/T genotype at position -511 and the C/C genotype at position -31 were associated with H. pylori infection and with an increased risk of gastritis in H. pylori-positive patients. Additionally, strains from patients H. pylori-positive carrying the cagA gene was significantly related with the T/T genotype at position -511 of IL-1B.  No association of polymorphisms at position +3954 of IL-1B and in the IL-1RN with H. pylori infection and with risk of severe gastric diseases was found. Conclusions: We demonstrated that polymorphisms in the promoter region of the IL-1B gene (at positions -511 and -31) are associated with an enhanced risk of H. pylori infection as well as gastritis in H. pylori-positive patients.

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