scholarly journals DEVELOPMENT OF RESISTANCE TO CHLORPYRIFOS-METHYL IN APHIS CRACCIVORA KOCH AND ITS IMPACT ON CERTAIN BIOLOGICAL ACTIVITIES

2021 ◽  
Vol 26 (4) ◽  
pp. 689-702
Author(s):  
Rehab Abd-Allah ◽  
Abd El Hamid Mohanna ◽  
Hamza El-Sharkawy ◽  
Mostafa Hashem
2021 ◽  
Vol 12 (3) ◽  
pp. 151-157
Author(s):  
S. Routray ◽  
◽  
H. P. Mishra ◽  

Thiamethoxam is a neonicotinoid group of insecticide which are selective agonists of the insect nicotinic acetylcholine receptor (nAChR), a pentameric cys-loop ligand-gated ion channel located in the central nervous system of insects. They provide farmers with invaluable, highly effective tools against some of the world’s most destructive crop pests. Black legume aphids, Aphis craccivora is one of the devastating polyphagous pests in agroecosystem and to manage their population, farmers are still relying on application of synthetic insecticides like Thiamethoxam. To evaluate the risk of resistance development, selection of A. craccivora was done to characterize Thiamethoxam resistance along with evaluation of developmental and reproductive fitness cost of the resistance. About 86.19 folds of resistance were developed after selecting for 24 generations. In the first twelve generations steady development of resistance was noticed followed by development become stiffer till 16th generation and more or less stable till 24th generations. Relative fitness of the selected resistant strain of aphids was decreased with longer nymphal duration and adult longevity. The mean nymphal duration was increased from 4.35±1.02 days (in F0) to 7.9±0.57 days (in F24). The fecundity rate was significantly less in resistant population (16.0±5.34) as compared to the susceptible strain (54.71±7.63) whereas, oviposition periods were significantly longer (12.49±1.44 days) in resistant population as compare to susceptible strain (9.50±1.22 days).


2017 ◽  
Vol 17 (2) ◽  
pp. 200-209 ◽  
Author(s):  
Thomson Patrick Joseph ◽  
Warren Chanda ◽  
Arshad Ahmed Padhiar ◽  
Samana Batool ◽  
Shao LiQun ◽  
...  

Cancer is the leading cause of morbidity and mortality around the globe. For certain types of cancer, chemotherapy drugs have been extensively used for treatment. However, severe side effects and the development of resistance are the drawbacks of these agents. Therefore, development of new agents with no or minimal side effects is of utmost importance. In this regard, natural compounds are well recognized as drugs in several human ailments, including cancer. One class of fungi, “mushrooms,” contains numerous compounds that exhibit interesting biological activities, including antitumor activity. Many researchers, including our own group, are focusing on the anticancer potential of different mushrooms and the underlying molecular mechanism behind their action. The aim of this review is to discuss PI3K/AKT, Wnt-CTNNB1, and NF-κB signaling pathways, the occurrence of genetic alterations in them, the association of these aberrations with different human cancers and how different nodes of these pathways are targeted by various substances of mushroom origin. We have given evidence to propose the therapeutic attributes and possible mode of molecular actions of various mushroom-originated compounds. However, anticancer effects were typically demonstrated in in vitro and in vivo models and very limited number of studies have been conducted in the human population. It is our belief that this review will help the research community in designing concrete preclinical and clinical studies to test the anticancer potential of mushroom-originated compounds on different cancers harboring particular genetic alteration(s).


2021 ◽  
Vol 19 (1) ◽  
pp. 139-154
Author(s):  
MA Hossain ◽  
MS Yasmin ◽  
MAA Bachchu ◽  
MA Alim

Botanicals are promising and attractive alternatives for pest management. In the present study, three botanical oils namely neem (Azadirachta indica), karanja (Pongamia pinnata) and mehogony (Swietenia mahagoni) were tested against the nymphs of Aphis craccivora Koch to evaluate the toxic and repellent effects under laboratory conditions (25 ± 5oC, 65-75% RH). Four concentrations (0.5, 1.0, 1.5, and 2.0%) along with control were maintained with distilled water and tween-20 was used as emulsifier. Leaf dipped method were used for insect bioassay. Insect mortality was recorded at 24, 48 and 72 hours after intervals while repellency was carried out at 2 hours after intervals upto 10th hours and the collected data were analyzed through MSTAT-C program. Results indicated that all the tested oils had toxic and repellent effects against the A. craccivora nymphs. Among the tested botanical oils, no significant difference was observed in terms of mortality over treatment time. But significant difference was noticed over level of concentrations exerted by the botanical oils. The average highest mortality (28.62%) was recorded by the application of mehogony oil whereas neem oil showed the lowest mortality (27.21%) against the A. craccivora and the mortality was directly proportional to the level of concentrations and hour after treatment (HAT). Probit analysis showed the lowest LD50 values of mehogony oil which revealed the highest toxic effect against the nymph of bean aphid. The highest repellent effect (77.33%) was found in mehogony oil (repellent class IV) among all the botanical oils applied. On the contrary, neem (57.33%) and karanja (55.00%) oils belonged to the same repellent class that is repellent class II. Although all the tested botanical oils evaluated showed toxic and repellent effects but mehogony oil performed as the best potent oil against the nymphs. We therefore suggested using the mehogony oil for the management of bean aphid. SAARC J. Agric., 19(1): 139-154 (2021)


1976 ◽  
Vol 66 (2) ◽  
pp. 331-333 ◽  
Author(s):  
J. A. K. Farrell

AbstractIn two trials, at Chitedze, Malawi, in 1966–1967, the spread of rosette virus disease in groundnuts (Arachis hypogaea) intersown with field beans (Phaseolus vulgaris) was less than the spread in groundnut monocultures comprising plant populations equivalent to the number of groundnut plants and to the total number of plants in the intersown crop. In one trial, numbers of early rosette transmissions were related to numbers of alate Aphis craccivora Koch, the vector of the virus, found on groundnut plants. Immigrant alate A. craccivora settling on the intersown crop were trapped by the hooked epidermal hairs of the bean plants and the observed reduction of rosette infection in the intersown crop was attributed to this effect. Inter-sowing with beans is considered less effective than early-sown, high-density monoculture as a method of reducing groundnut rosette infections and yields of groundnuts from inter-sown crops may be lower than those obtained from high-density monoculture.


2019 ◽  
Vol 143 (6) ◽  
pp. 659-669
Author(s):  
Seydou Diabate ◽  
Emilie Deletre ◽  
Lucy Kananu Murungi ◽  
Komi K.M. Fiaboe ◽  
John Wesonga ◽  
...  

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 243 ◽  
Author(s):  
Daniela R. P. Loureiro ◽  
José X. Soares ◽  
Joana C. Costa ◽  
Álvaro F. Magalhães ◽  
Carlos M. G. Azevedo ◽  
...  

Marine organisms represent almost half of total biodiversity and are a very important source of new bioactive substances. Within the varied biological activities found in marine products, their antimicrobial activity is one of the most relevant. Infectious diseases are responsible for high levels of morbidity and mortality and many antimicrobials lose their effectiveness with time due to the development of resistance. These facts justify the high importance of finding new, effective and safe anti-infective agents. Among the variety of biological activities of marine xanthone derivatives, one that must be highlighted is their anti-infective properties. In this work, a literature review of marine xanthones with anti-infective activity, namely antibacterial, antifungal, antiparasitic and antiviral, is presented. Their structures, biological activity, sources and the methods used for bioactivity evaluation are described. The xanthone derivatives are grouped in three sets: xanthones, hydroxanthones and glycosylated derivatives. Moreover, molecular descriptors, biophysico-chemical properties, and pharmacokinetic parameters were calculated, and the chemical space occupied by marine xanthone derivatives is recognized. The chemical space was compared with marketed drugs and framed accordingly to the drug-likeness concept in order to profile the pharmacokinetic of anti-infective marine xanthone derivatives.


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