scholarly journals EVALUATING NUTRITIONAL STATUS OF CHILDREN WITH CANCER (ACUTE LYMPHOBLASTIC LEUKEMIA - ACUTE MYELOID LEUKEMIA) USING TUBE FEEDING

2017 ◽  
Vol 2017 (48) ◽  
pp. 559-573
Author(s):  
أحمد کريم سيد حسن ◽  
خالد على شاهين
2020 ◽  
Vol 1 (2) ◽  
Author(s):  
Ronald Rompies ◽  
Hubert I Tatara ◽  
Stefanus Gunawan

Abstract: Information about nutrition and parents’ experience are very important in supporting the nutrition of children with cancer. This study was aimed to obtain the parents’ understanding about nutrition of children with cancer. We used modified structured questionnaire about diet and sanitation which were already validation testing. The results showed that there were 38 complete questionnaires consisted of acute lymphoblastic leukemia (ALL) in 14 children (36.8%), followed by acute myeloid leukemia (AML) in 8 children, and retinoblastoma in 7 children. The majority of parents were housewives (84%) meanwhile senior high school educated was the most common education (57.8% of mothers and 52.6% of fathers)). All parents changed the diet style of their children after diagnosed as cancer. Most parents (78.9%) answered that food could cause cancer, and (94.7%) avoided certain foods; (78.9%) chose junk food as avoided food; and during treatment, (89.4%) gave special foods which were high protein, fruits, vegetables, and milk. Most parents (94.7%) answered that children with cancer had to avoid street foods, and (94.7%) chose mineral water as a safe drink. In conclusion, education of medical workers about nutrition of children with cancer is needed to achieve agreement in optimal nutrition.Keywords: nutrition of children with cancer Abstrak: Informasi mengenai kebutuhan nutrisi dan pengalaman orang tua berperan penting dalam menunjang nutrisi anak dengan kanker. Penelitian ini bertujuan untuk mengetahui pemahaman orang tua tentang nutrisi yang optimal bagi anak dengan kanker. Pada penelitian ini digunakan kuesioner terstruktur tentang diet dan kebersihan yang dimodifikasi, teruji dengan validitas isi. Hasil penelitian mendapatkan 38 kuesioner yang diisi lengkap, dengan diagnosis terbanyak acute lymphoblastic leukemia (ALL) pada 14 anak (36,8%), diikuti acute myeloid leuke-mia (AML) 8 anak, dan retinoblastoma 7 anak. Mayoritas orang tua memiliki pekerjaan ibu rumah tangga (84%) dan pendidikan terakhir yang terbanyak ialah SMA (ibu 57,8% dan ayah 52,6%). Semua orang tua merubah pola makan anak mereka setelah terdiagnosis kanker. Sebagian besar orang tua (78,9%) menjawab makanan dapat menyebabkan kanker dan (94,7%) menghindari makanan tertentu; (78,9%) memilih junk food sebagai makanan yang harus dihindari; dan (89,4%) memberikan makanan khusus selama pengobatan mengandung tinggi protein, buah, sayur, dan susu. Sebagian besar orang tua (94,7%) menjawab anak penderita kanker tidak boleh makan makanan di pinggir jalan, dan (94,7%) memilih air mineral sebagai minuman yang aman untuk diminum. Simpulan penelitian ialah perlu dilakukan edukasi dan penyuluhan oleh tenaga medis tentang nutrisi untuk anak kanker agar terdapat kesepahaman dalam pemberian nutrisi yang optimal.Kata kunci: nutrisi anak dengan kanker


2021 ◽  
pp. 72-74
Author(s):  
Sarat Das ◽  
Prasanta Kr. Baruah ◽  
Sandeep Khakhlari ◽  
Gautam Boro

Introduction: Leukemias are neoplastic proliferations of haematopoietic stem cells and form a major proportion of haematopoietic neoplasms that are diagnosed worldwide. Typing of leukemia is essential for effective therapy because prognosis and survival rate are different for each type and sub-type Aims: this study was carried out to determine the frequency of acute and chronic leukemias and to evaluate their clinicopathological features. Methods: It was a hospital based cross sectional study of 60 patients carried out in the department of Pathology, JMCH, Assam over a period of one year between February 2018 and January 2019. Diagnosis was based on peripheral blood count, peripheral blood smear and bone marrow examination (as on when available marrow sample) for morphology along with cytochemical study whenever possible. Results: In the present study, commonest leukemia was Acute myeloid leukemia (AML, 50%) followed by Acute lymphoblastic leukemia (ALL 26.6%), chronic myeloid leukemia (CML, 16.7%) and chronic lymphocytic leukemia (CLL, 6.7%). Out of total 60 cases, 36 were male and 24 were female with Male:Female ratio of 1.5:1. Acute lymphoblastic leukemia was the most common type of leukemia in the children and adolescents. Acute Myeloid leukemia was more prevalent in adults. Peripheral blood smear and bone Conclusion: marrow aspiration study still remains the important tool along with cytochemistry, immunophenotyping and cytogenetic study in the diagnosis and management of leukemia.


2017 ◽  
Vol 11 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Mirella Ampatzidou ◽  
Charikleia Kelaidi ◽  
Michael N. Dworzak ◽  
Sophia Polychronopoulou

Author(s):  
Jing Liu ◽  
Shu-xu Dong ◽  
Ying Li ◽  
Yi-dan Xu ◽  
Yong-xin Ru

Pseudo Chediak-Higashi (PCH) granules are mainly common in acute myeloid leukemia. Here we found a patient diagnosed with common-B acute lymphoblastic leukemia(ALL) with PCH cytoplasmic granules, which was rarely seen in daily diagnosis. The morphology of the granules is different in transmission electron microscope (TEM) from cases reported before. There is a vesicle with various-sized particles surrounding the nucleus, in addition to the particles, a multiple-layer membrane structure was also detected in the vesicle.


Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 26-27
Author(s):  
Shehab Fareed Mohamed ◽  
Elabbass Abdelmahmuod ◽  
Elrazi Awadelkarim A Ali ◽  
Abdulqadir Jeprel Nashwan ◽  
Dina Sameh Soliman ◽  
...  

Introduction Acute leukemias can be divided into acute myeloid leukemia and acute lymphoblastic leukemia. Common presentations of acute leukemia include fever, symptoms of anemia, bleeding, bone pain palpable Lymph nodes or spleen and symptoms due inflation or leukocystasis. Extramedullary mass is rare and can be of myeloid tissue and known as Chloroma or myeloid (granulocytic) sarcoma which one of the WHO classifications for acute myeloid leukemia. Common sites of occurrence are skin, sinuses, bone and other. It's rarely involve central nervous system. Spinal cord involvement usually manifest as epidural mass causing cord compression. Spinal epidural tumor with acute leukemia and myeloid sarcoma is rare and can be found in 3-9% in patients with leukemia. In this review we decide to review the cases of spinal cord compression caused by acute myeloid leukemia (including Chloroma) and acute lymphoblastic leukemia due to the significance of such presentation in addition to reports that Myeloid sarcoma of the spine has very poor prognosis Methodology: We have reviewed the literature using: PubMed, google scholar, Scopus for patient with spinal cord compression and acute leukemia. We used the search term and synonyms : : acute myeloid leukemia , acute myelocytic leukemia , acute monocytic leukemia , acute lymphoblastic leukemia , acute lymphoid leukemia, chloroma , myeloid sarcoma ,granulocytic sarcoma, spinal cord compression .We included adult patients above 18 years old only cases we exclude pediatrics cases and cases of chronic leukemia's and other myeloproliferative disorders as well as cases of central nervous system involvement other than spinal cord Results We gathered the information from 98 cases with general demographics, presentation, image modality, cytogenetics and molecular in addition to management and outcome. We have found mean age for the patients is 38 years old with male predominance with 70% of the cases. The most presenting symptom was back pain in around 75% of the cases. Neurological findings showed sensory loss and parapreresis in most of the documented cases. MRI was most performed modality of imaging 63% followed by Computed tomography(CT) 15 % and then myelogram 13 %, which is least used due to invasive nature and before the era of MRI. The most common affected site on spinal cord were thoracic followed by lumbar. Cytogenetics and molecular data was not reported in most of the cases. Patients were treated with either steroids or surgery or radiotherapy and or chemotherapy while few underwent bone marrow transplant, but the most common approach was surgery+ radiotherapy + chemotherapy combination. Steroids used in most of the cases especially in the cases of acute lymphoblastic leukemia and dexamethasone was the steroids of the choice mainly. The outcome of the patients were variable, 30 % were alive at the time of the reports 30 % died and 30 % between relapse and complete remission. Conclusions Acute leukemia can be presented as mass causing spinal cord compression which is very serious. There are is no standardized management of patients with acute leukemia who presented with spinal cord compression nether guidelines or steps to follow. Some reports speculated also specific morphology and cytogenetics association with predisposition to have Extramedullary mass, however there lack of reporting of such a valuable information. Large studies including all adjusted variables required to determine if spinal cord compression presentation can be an independent risk facto or not Effective diagnosis and prompt action should take place. Figure Disclosures No relevant conflicts of interest to declare.


2016 ◽  
Author(s):  
Richard A. Larson ◽  
Roland B Walter

The acute leukemias are malignant clonal disorders characterized by aberrant differentiation and proliferation of transformed hematopoietic progenitor cells. These cells accumulate within the bone marrow and lead to suppression of the production of normal blood cells, with resulting symptoms from varying degrees of anemia, neutropenia, and thrombocytopenia or from infiltration into tissues. They are currently classified by their presumed cell of origin, although the field is moving rapidly to genetic subclassification. This review covers epidemiology; etiology; classification of leukemia by morphology, immunophenotyping, and cytogenetic/molecular abnormalities; cytogenetics of acute leukemia; general principles of therapy; acute myeloid leukemia; acute lymphoblastic leukemia; and future possibilities. The figure shows the incidence of acute leukemias in the United States. Tables list World Health Organization (WHO) classification of acute myeloid leukemia and related neoplasms, expression of cell surface and cytoplasmic markers for the diagnosis of acute myeloid leukemia and mixed-phenotype acute leukemia, WHO classification of acute lymphoblastic leukemia, WHO classification of acute leukemias of ambiguous lineage, WHO classification of myelodysplastic syndromes, European LeukemiaNet cytogenetic and molecular genetic subsets in acute myeloid leukemia with prognostic importance, cytogenetic and molecular subtypes of acute lymphoblastic leukemia, terminology used in leukemia treatment, and treatment outcome for adults with acute leukemia. This review contains 1 highly rendered figure, 9 tables, and 117 references.


2014 ◽  
Vol 8 (2) ◽  
pp. 825-830 ◽  
Author(s):  
WENJIAN GUO ◽  
AISHU DONG ◽  
CHAO XING ◽  
XIAOJI LIN ◽  
XIAHUI PAN ◽  
...  

2009 ◽  
Vol 2 (1) ◽  
Author(s):  
Hilmar Quentmeier ◽  
Björn Schneider ◽  
Sonja Röhrs ◽  
Julia Romani ◽  
Margarete Zaborski ◽  
...  

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