Impact of COVID-19 Pandemic on COMPI Fertility Problem Stress Scale and the State-Trait Anxiety Scale in Patients Undergoing IVF/ICSI

Gynecology Obstetrics and Reproductive Medicine ◽

10.21613/gorm.2021.1187 ◽

2021 ◽

pp. 1-7

Author(s):

Arzu Yurci ◽

Saban Karayagiz

Keyword(s):

In Vitro Fertilization ◽

Trait Anxiety ◽

Correlation Coefficients ◽

Anxiety Scale ◽

Lower State ◽

Cross Sectional ◽

Vitro Fertilization ◽

Stress Scale ◽

Fertility Problem

OBJECTIVE: This study aimed to investigate the effect of the COVID-19 outbreak on infertile couples dealing with stress and anxiety during in vitro fertilization treatment. STUDY DESIGN: 252 infertile patients who applied for in vitro fertilization treatment were included in this cross-sectional study. Data were collected via four data collection tools including socio-demographic form, COVID-19 Inventory (COVID-I), COMPI fertility problem stress scale (COMPI-FPSS), and state-trait anxiety scale. Data analysis was conducted by SPSS statistical software included statistical analysis such as averages, standard deviations, correlation, regression, and t-test. RESULTS: Both negative and weak correlations were found between COMPI fertility problem stress scale and subscales of state-trait anxiety scale as well as the total score of state-trait anxiety scale. In terms of socio-demographic characteristics of the participants and their responses in state-trait anxiety scale and ISS forms, the correlation coefficients were also so low. The results also showed that public officials, health professionals, and educators showed lower state-trait anxiety scale (stress-related anxiety) scores. CONCLUSION: During the COVID-19 pandemic, there was an increase in spontaneous pregnancy expectations. Although participants were mostly stressed because of the COVID-19 outbreak, they didn’t change their in vitro fertilization treatment plans during the outbreak.

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The Effect of Stress, Anxiety and Depression on In Vitro Fertilization Outcome in Kazakhstani Public Clinical Setting: A Cross-Sectional Study

Journal of Clinical Medicine ◽

10.3390/jcm10050937 ◽

2021 ◽

Vol 10 (5) ◽

pp. 937

Author(s):

Gauri Bapayeva ◽

Gulzhanat Aimagambetova ◽

Alpamys Issanov ◽

Sanja Terzic ◽

Talshyn Ukybassova ◽

...

Keyword(s):

In Vitro Fertilization ◽

Depressed Mood ◽

Depression Scale ◽

Anxiety Scale ◽

Clinical Depression ◽

Cross Sectional ◽

Vitro Fertilization ◽

Scale Scores ◽

The Impact

Although it is clear that infertility leads to heightened stress for patients, the impact of depressed mood and anxiety on treatment outcome is inconsistently reported. The aim of this study was to evaluate the effect of stress, depression and anxiety on in vitro fertilization (IVF) outcomes in Kazakhstani public assisted reproductive technology (ART) clinics. The prospective cohort study was performed between June 2019 and September 2020 using questionnaires to assess psychological stress, depressed mood and anxiety in women referred to IVF clinics in two public clinical centers in Kazakhstan, Nur-Sultan and Aktobe. Our study sample comprised 142 women with the average age of 33.9 ± 4.9 years, and infertility duration 6.0 ± 3.5 years. More than half of respondents had Center for Epidemiological Studies Depression Scale (CES-D) scores higher than 16, indicating their risk of developing clinical depression. Ninety-one percent of women from Aktobe city were at risk for clinical depression (p < 0.001). Aktobe city respondents had higher stress subscale scores and anxiety scale scores (p < 0.001) than Nur-Sultan respondents. Statistical analysis showed that IVF outcome was not significantly associated with depression and stress, while the higher anxiety scale scores were negatively associated with clinical pregnancy after IVF.

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Association of state and trait anxiety to semen quality of in vitro fertilization patients: a controlled study

Fertility and Sterility ◽

10.1016/j.fertnstert.2013.01.098 ◽

2013 ◽

Vol 99 (6) ◽

pp. 1565-1572.e2 ◽

Cited By ~ 24

Author(s):

Elisa Vellani ◽

Alessandro Colasante ◽

Luciana Mamazza ◽

Maria Giulia Minasi ◽

Ermanno Greco ◽

...

Keyword(s):

In Vitro Fertilization ◽

Trait Anxiety ◽

Semen Quality ◽

Controlled Study ◽

Vitro Fertilization ◽

State And Trait Anxiety

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Factors that influence in vitro fertilization treatment outcomes of Chinese men: A cross-sectional study

Applied Nursing Research ◽

10.1016/j.apnr.2016.07.003 ◽

2016 ◽

Vol 32 ◽

pp. 222-226 ◽

Cited By ~ 4

Author(s):

Dan Chen ◽

Jing Ping Zhang ◽

Ling Jiang ◽

Huayan Liu ◽

Ling Shu ◽

...

Keyword(s):

In Vitro Fertilization ◽

Treatment Outcomes ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Vitro Fertilization ◽

Chinese Men

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A Two-year Cross-sectional Prospective Study for Assessment of Endometrial Thickness and Volume using Three-dimensional Transvaginal Ultrasound among in vitro Fertilization Patients of Royan Institute in Iran

Donald School Journal of Ultrasound in Obstetrics & Gynecology ◽

10.5005/jp-journals-10009-1491 ◽

2016 ◽

Vol 10 (4) ◽

pp. 398-402

Author(s):

Firoozeh Ahmadi ◽

Farnaz Akhbari ◽

SH Irani ◽

M Shiva ◽

A Maghari

Keyword(s):

In Vitro Fertilization ◽

Prospective Study ◽

Endometrial Thickness ◽

Transvaginal Ultrasound ◽

Three Dimensional ◽

Controlled Ovarian Hyperstimulation ◽

Cross Sectional ◽

Vitro Fertilization ◽

Group I

ABSTRACT Introduction To evaluate the role of endometrial thickness and volume using three-dimensional transvaginal ultrasound (3-D TVUS) in order to predict pregnancy outcome in assisted reproductive technology (ART) cycle on the day of human chorionic gonadotropin (hCG) administration. Materials and methods In this prospective study, the long protocol of controlled ovarian hyperstimulation was prescribed for women. Endometrial thickness and volume were measured using the 3-D TVUS, for 166 women undergoing ART cycle, on the day of hCG administration at Royan Institute, Tehran, Iran, between 2009 and 2011. All patients were divided into three groups. Regarding endometrial thickness, there are three groups as follows: Group I: . 7 mm, group II: 7.14 mm, and group III: > 14 mm; all patients were also divided into three groups according to endometrial volume calculated as follows: Group IV: < 2 cc, group V: 2.4.5 cc, group VI: > 4.5 cc. Pregnancy rate (PR) was compared between all groups. Results A total of 166 patients were analyzed. Overall PR was 39.8% after in vitro fertilization (IVF). Participant's age ranged from 20 to 38 years old with the mean age of 29.9 ± 4.23. No significant cut-off value was found for endometrial thickness and volume. Conclusion Endometrial thickness and volume on the day of hCG are significant in limited value and in a clinical setting for predicting implantation in ART cycle. How to cite this article Ahmadi F, Akhbari F, Irani SH, Shiva M, Maghari A. A Two-year Cross-sectional Prospective Study for Assessment of Endometrial Thickness and Volume using Threedimensional Transvaginal Ultrasound among in vitro Fertilization Patients of Royan Institute in Iran. Donald School J Ultrasound Obstet Gynecol 2016;10(4):398-402.

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Psychological status of infertile patients who had in vitro fertilization treatment interrupted or postponed due to COVID-19 pandemic: a cross-sectional study

Journal of Psychosomatic Obstetrics & Gynecology ◽

10.1080/0167482x.2020.1853095 ◽

2020 ◽

pp. 1-8

Author(s):

Fabio Barra ◽

Valentina Lucia La Rosa ◽

Salvatore Giovanni Vitale ◽

Elena Commodari ◽

Michele Altieri ◽

...

Keyword(s):

In Vitro Fertilization ◽

Cross Sectional Study ◽

Psychological Status ◽

Sectional Study ◽

Cross Sectional ◽

Vitro Fertilization ◽

Infertile Patients

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Basal follicle stimulating hormone and leptin on the day of hCG administration predict successful fertilization in in vitro fertilization

Medical Journal of Indonesia ◽

10.13181/mji.v25i1.1215 ◽

2016 ◽

Vol 25 (1) ◽

pp. 39-43 ◽

Cited By ~ 1

Author(s):

Andon Hestiantoro ◽

Budi Wiweko ◽

Robert H. Purwaka

Keyword(s):

In Vitro Fertilization ◽

Follicle Stimulating Hormone ◽

Oocyte Retrieval ◽

Cross Sectional Study ◽

Mature Oocyte ◽

Cross Sectional ◽

Vitro Fertilization ◽

Fertility Clinic ◽

Stimulating Hormone

Background: Successful pregnancy in in vitro fertilization (IVF) program depends on multiple factors. This study aimed to determine whether age, body mass index (BMI), basal follicle stimulating hormone (FSH), estradiol, and leptin on the day of trigger ovulation with human chorionic gonadotropin (hCG) might be used as predictor for successful oocyte fertilization in in vitro fertilization (IVF) program.Methods: This is a cross sectional study conducted in Yasmin Fertility Clinic, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Forty participating patients underwent IVF program, excluding smokers, patients with diabetic, morbid obesity, and severe oligospermia or azoospermia. Age, BMI, basal FSH, estradiol, leptin on the day of hCG administration, oocyte count on oocyte retrieval, the number of mature oocyte, and fertility rate were analyzed using bivariate and multivariate analysis to determine which eligible factors play role in predicting the successful of fertilization.Results: Significant correlation was found between basal FSH level and serum leptin/oocyte ratio on the day of hCG administration with successful fertilization. We found probability formula as follows: 1/(1+exp –(6.2 - 0.4(leptin serum/oocyte ratio) - 0.8(basal FSH)), with 77.8% sensitivity, 77.8% specificity, and AUC levels of 85.6% indicating strong predictability. Probability of successful fertilization related to basal FSH level of 5.90 mIU/mL and leptin serum/oocyte ratio of 3.98.Conclusion: The formula consisting of basal FSH and leptin serum/oocyte ratio on the day of trigger ovulation was capable in predicting the probability of successful fertilization in IVF procedure.

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Two direct radioimmunoassays for 17 beta-estradiol evaluated for use in monitoring in vitro fertilization.

Clinical Chemistry ◽

10.1093/clinchem/30.5.787 ◽

1984 ◽

Vol 30 (5) ◽

pp. 787-790 ◽

Cited By ~ 7

Author(s):

R V Haning ◽

S M Meier ◽

L M Boehnlein ◽

M Gerrity ◽

S S Shapiro

Keyword(s):

In Vitro Fertilization ◽

Solid Phase ◽

Correlation Coefficients ◽

Comparison Method ◽

Ovarian Activity ◽

Vitro Fertilization ◽

Serum Pool ◽

Clinically Significant ◽

Ultrasound Parameters

Abstract Two direct 125I radioimmunoassays for 17 beta-estradiol were evaluated by comparing results with those obtained by a comparison RIA involving extraction and chromatography (x) and with ultrasound parameters of ovarian activity. The correlation coefficients (R2) for the Immuchem Covalent-Coat Solid Phase 125I results (y1) and the Pantex Immuno-direct results (y2) with the comparison method results were 0.56 and 0.96, respectively, after log transformation of data (N = 42). Similar differences were observed in the correlations with the ultrasound parameters. We also evaluated the untransformed data by linear regression and obtained: y1 = 254 + 0. 410x (R2 = 0.65) and y2 = 48.2 + 0. 749x (R2 = 0.96). Between- and within-assay variations for a serum pool containing 17 beta-estradiol at 1278 pg/mL were respectively 9.0% and 9.4% for Immuchem , 3.3% and 6.7% for Pantex , and 7.3% and 9.4% for the comparison method; for the 267 pg/mL pool, these were 21.8% and 16.6% for Immuchem , 4.7% and 4.6% for Pantex , and 21.2% and 13.1% for the comparison method. Differences in the results obtained with the Pantex method and the comparison method were not clinically significant for monitoring superovulation for in vitro fertilization; the performance of the Immuchem method was less satisfactory.

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Luteinizing hormone changes in gonadotropin-releasing hormone antagonist protocol in in vitro fertilization cycles: A cross-sectional study

International Journal of Reproductive BioMedicine ◽

10.18502/ijrm.v17i3.4520 ◽

2019 ◽

Author(s):

Batool Hosein Rashidi ◽

Roya Kabodmehri ◽

Mamak Shariat ◽

Ensieh Shahrokh Tehraninejad ◽

Alireza Abdollahi ◽

...

Keyword(s):

In Vitro Fertilization ◽

Luteinizing Hormone ◽

Cross Sectional Study ◽

Gonadotropin Releasing Hormone ◽

Sectional Study ◽

Cross Sectional ◽

Vitro Fertilization ◽

Releasing Hormone ◽

Antagonist Protocol

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Prevalence of asymptomatic SARS-CoV-2 Infection in couples seeking in vitro fertilization treatment in Riyadh, July–November, 2020

Obstetrics & Gynecology International Journal ◽

10.15406/ogij.2021.12.00593 ◽

2021 ◽

Vol 12 (5) ◽

pp. 284-287

Author(s):

Khalid Arab Awartani ◽

Amani Aldriweesh ◽

Ali Alhibshi ◽

Fatimah Abualsaud

Keyword(s):

In Vitro Fertilization ◽

Retrospective Cohort ◽

Healthcare Workers ◽

Cross Sectional ◽

Vitro Fertilization ◽

Fertility Cycle ◽

Reproductive Services ◽

Study Setting ◽

Negative Conclusion

Background: After the start of the coronavirus disease (COVID-19) pandemic, assisted reproductive services were suspended and restarted in in vitro fertilization (IVF) clinics worldwide. In our center we implemented screening of all couples for COVID-19 the day before starting the ovulation cycle and before the ovum pick-up (OPU) procedure. Objectives: Assess the prevalence of asymptomatic COVID-19 among couples undergoing in vitro fertilization (IVF). Design: Cross-sectional and retrospective cohort study. Setting: An IVF unit in Riyadh from July to November 2020. Patients and methods: Patients and their partners were tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection 24-48 hours before their initial visit to initiate the fertility cycle and again prior to the ovum pick-up visit. Main outcome measures: Prevalence of asymptomatic SARS-CoV-2 infection. Sample size: 508 couples. Results: A total of 508 couples were tested. Of the 508 cycles of therapy, 24 (4.7%) were cancelled, 16 (3.14%) before the start of the cycle, and 8 (1.66%) before ovum pick-up, because one or both partners in the couple tested SARS-CoV-2 positive. Before the start of the cycle, 3 patients and their partners both tested positive; 7 patients tested positive and their partners tested negative; and 6 partners tested positive and the patient testing negative. In addition, on retesting 481 couples before OPU 3 patients and their partners both tested positive; 3 patients tested positive, and their partners tested negative; and 2 partners tested positive and the patients tested negative. Conclusion: The prevalence of asymptomatic SARS-CoV-2 infection in couples seeking IVF was higher than that in the general population. Implementing a policy of screening couples for SARS-CoV-2 prior to IVF treatment, minimized the possibility of transmission of SARS-CoV-2 from patients to healthcare workers.

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