Experts representing different parts of the team involved in clinical trials came together on a call to discuss the current state of conducting clinical trials in PAH. Below is the account of the invigorating conversation moderated by guest editor Harrison Farber, MD, from Boston University, with Frederic Bodin, MD, VP, Head, Global Medical Science and Communication, Actelion; Scott Halpern, MD, PhD, MBE, University of Pennsylvania, and Rino Aldrighetti, President, Pulmonary Hypertension Association.