Lifestyle-Related Risk Factors, Smoking Status and Cardiovascular Disease

2012 ◽  
Vol 19 (2) ◽  
pp. 85-92
Author(s):  
Renata Giudice ◽  
Raffaele Izzo ◽  
Maria Virgina Manzi ◽  
Giampiero Pagnano ◽  
Mario Santoro ◽  
...  
2012 ◽  
Vol 19 (2) ◽  
pp. 85-92
Author(s):  
Renata Giudice ◽  
Raffaele Izzo ◽  
Maria Virgina Manzi ◽  
Giampiero Pagnano ◽  
Mario Santoro ◽  
...  

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Martin Lajous ◽  
Laura Tondeur ◽  
Agnes Fournier ◽  
Francoise Clavel-Chapelon

Background: There is controversy over whether cardiovascular disease and venous thromboembolism (VTE) share risk factors. Prospective information on risk factors for VTE in otherwise healthy individuals is limited. Methods and Results We evaluated the relation between known risk factors for cardiovascular disease and incidence of VTE among 65,272 French women in the E3N prospective cohort study with no prior history of VTE and who were free of cardiovascular disease or cancer in 1993. All information was self-reported via mailed questionnaires and diet and physical activity were assessed using previously validated instruments. Between 1993 and 2007, 766 cases of deep vein thrombosis or pulmonary embolism were first identified through self-reports and validated using medical records and information from treating physicians. Cases were considered valid if the diagnosis was based on an imaging procedure. We evaluated the following risk factors: education, menopause, postmenopausal hormone use, treated hypercholesterolemia and hypertension, diabetes, body mass index (BMI), physical activity, smoking status and intake of alcohol, red meat, fish, fruits and vegetables, fiber and coffee. In a multivariable model with age as the time scale, we found that, compared to women with a BMI <22 kg/m2, the HR (95%CI) was 1.35 (1.14, 1.60) for 22–24.9 kg/m2, 2.11 (1.73, 2.57) for 25–29.9 kg/m2 and 2.88 (2.08, 3.98) for ≥30 kg/m2 and the p-trend was <0.0001. Menopause was found to be inversely associated with VTE risk [HR=0.60 (95%CI 0.45–0.80); postmenopausal vs. premenopausal women]. In analyses restricted to postmenopausal women, relative to never users current use of postmenopausal hormones was significantly associated to VTE risk [HR=1.44 (95%CI 1.18–1.74)]. No significant association was found with dietary and other cardiovascular risk factors. Conclusion In this large prospective study only some risk factors for cardiovascular disease were associated to VTE incidence. We observed a strong inverse association between menopause and VTE.


2020 ◽  
Vol 30 (4) ◽  
pp. 329-334
Author(s):  
Josiane Luzia Sibioni Moraes ◽  
Ramon Antonio Oliveira ◽  
Marcos Naoyuki Samano ◽  
Vanessa de Brito Poveda

Background: Surgical site infections (SSIs) are among the leading health care–associated infections as well as a major problem in the postoperative period of lung transplant recipients. Little is known about the risk factors in this specific population. The objective of this study was to identify the incidence, risk factors, and outcomes of SSI following lung transplant. Methods: Digital medical records of adult recipients subjected to lung transplant from July 2011 and June 2016 in a large Brazilian referral teaching public center were analyzed in this retrospective cohort follow-up. Results: Among the 121 recipients analyzed, 19 (15.7%) had SSI; of these, 11 (57.8%) had superficial incisional infections, 1 (5.2%) had a deep incisional infection, and 7 (36.8%) had organ/space infection. Recipient-related risk factors for SSI were high body mass index ( P = .041), prolonged surgery time ( P = .043), and prolonged duration of chest drain placement ( P = .009). At the multiple logistic regression was found that each hour elapsed in the surgical time increased the odds of SSI by around 2 times (odds ratio 2.34; 95% CI, 1.46-4.53; P = .002). Donor-related risk factors included smoking status ( P = .05) and positive bronchoalveolar lavage ( P < .001). Having an SSI was associated with an increased length of stay in intensive care units ( P = .003), reoperation ( P = .014), and a higher 1-year mortality rate ( P = .02). Conclusions: The identified incidence rate was higher to that observed in the previous studies. The risk factors duration of chest tube placement and donor smoking status are different from those reported in the scientific literature.


2018 ◽  
Vol 36 (5_suppl) ◽  
pp. 167-167
Author(s):  
Shahid Sattar Ahmed ◽  
Greg Andrew Durm ◽  
John Donatelli ◽  
Huan Yao ◽  
Yongmei Liu ◽  
...  

167 Background: We have previously shown that consolidation pembrolizumab after chemoradiation is safe in a 93 patient-clinical trial of unresectable stage III NSCLC patients (Durm, ASCO 2016). However 15 patients (16%) developed grade ≥2 pneumonitis. There is limited data on risk factors for developing pneumonitis in this population. We conducted a retrospective review of these patients to identify potential clinical, biologic, radiographic and radiation treatment related risk factors for developing pneumonitis. Methods: We evaluated ECOG PS, age, gender, smoking status, stage, histology, chemo regimen, consolidation chemotherapy, TILs, PDL-1 status, PFTs, PET SUVs, grade of pre-existing ILD, COPD and Radiation dosimetry plans. Logistic regression and fisher’s-exact test were used for the odds ratio and p-values. Results: See Table. [1] [1] Age, histology, stage, chemo, PFTs, SUVs and PDL1 were not significant [2] n = sample size p = pneumonitis [3] Moderate/severe COPD was not seen in any patients with pneumonitis despite 94% of participants being smokers. Conclusions: This preliminary report highlights the utility of a multi-disciplinary approach to develop risk-stratification models for pneumonitis in an at-risk patient population. However larger prospective studies are needed to validate their meaningful use in the clinical setting.[Table: see text]


2017 ◽  
Vol 3 (6) ◽  
pp. e162 ◽  
Author(s):  
Fabián Ballesteros ◽  
Julie Allard ◽  
Céline Durand ◽  
Héloïse Cardinal ◽  
Lyne Lalonde ◽  
...  

2020 ◽  
Vol 5 (1) ◽  
pp. 348
Author(s):  
Debie Anggraini ◽  
Prima Adelin

<p class="Default"><strong><em>Introduction</em></strong><em>: Cardiovascular disease (CVD) is a major cause of death and disability worldwide. The most stringent primary CVD screening guidelines in developed countries use absolute CVD risk scores or coronary heart disease, such as Framingham or SCORE (Systematic Coronary Risk Evaluation) there are two types of CVD risk factors namely modifiable risk factors and unmodified risk factors. <strong>The aim</strong> of the current study is to determine the profil of potentially modifiable and unmodified cardiovascular risk factors. <strong>Method</strong>: </em><em>This research consists of 41 elderly people which aged ≥ 60 years in Guguak, Kabupaten 50 Kota, West Sumatera, Indonesia. The data taken is modifiable risk factors consisting of diseases related risk factors </em><em>including blood pressure categories, lipid profile, central obesity, body mass index </em><em>and lifestyle related risk factors such as </em><em>smoking habit</em><em>. We also take data of unmodified risk factors such as age and gender</em><em>. <strong>The result</strong>: t</em><em>his study consists of 41 elderly people which aged ≥ 60 years in Guguak, Kabupaten 50 Kota, West Sumatera, Indonesia. The mean age of  elderly were 68</em><em>±</em><em>7.64861 years old that consisting of 29.3% men and 70.7% women, </em><em>34% of elderly with hypertension, the elderly with hypercholesterolemia 71%, hypertriglyceridemia 41%, and the elderly women with low HDL-C levels were 53%,  the elderly men with low HDL-C levels were 92%. <strong>Conclusion</strong><strong>: </strong>There are two types of risk factors CVD, modifiable risk factors and nonmodifiable risk factors. </em><em>The modifiable risk factors consisting of diseases related risk factors </em><em>including blood pressure categories, lipid profile, central obesity, body mass index </em><em>and lifestyle related risk factors such as </em><em>smoking habit.</em></p>


2013 ◽  
Vol 8 (1) ◽  
pp. 3-7 ◽  
Author(s):  
R Koju ◽  
R Gurung ◽  
P Pant ◽  
S Humagain ◽  
CM Yogol ◽  
...  

Background Cardiovascular disease (CVD) is a major cause of morbidity and mortality throughout the world including Nepal. The assessment of risk factors responsible for CVD can predict 10 year risk of CVD. World Health Organization (WHO) risk assessment chart, specially designed for South East Asia Sub-region D can predict the risk of CVD in Nepal. Method and Materials A total 532 study population from Panauti, Banepa and Dhulikhel were calculated their 10 year risk of CVD using WHO/ISH risk prediction chart on the basis of risk factors: age, gender, smoking status, diabetes, systolic blood pressure and total cholesterol. Result Ten year risk of developing cardiovascular disease is less than 10% among the population less than 50 years, irrespective of gender. 5% of male population had more than 10% chance of developing cardiovascular events in next ten years. One third of 60 – 69 years people had more than 10% chance of developing cardiovascular disease whereas it increased to 50% among 70 years and older group. Conclusion The assessment of risk factors is quite easy and cheap tool to predict the cardiovascular event, which support to practice the good clinical management to prevent the cardiovascular morbidity and mortality.  DOI: http://dx.doi.org/10.3126/njh.v8i1.8328 Nepalese Heart Journal Vol.8(1) 2011 pp.3-7


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