Antiviral pandemic risk assessment for urban receiving waters

2010 ◽  
Vol 61 (4) ◽  
pp. 879-884 ◽  
Author(s):  
J. B. Ellis

An 80% metabolic conversion of the Tamiflu® pro-drug (oseltamivir phosphate, OP) to its metabolite oseltamivir carboxylate (OC) and a high excretion rate combined with poor removal at sewage treatment works (STWs) means that potentially high STW OC emissions may occur in receiving waters. A risk assessment approach undertaken within the River Lee catchment in North East London indicates that predicted environmental concentrations for surface waters (PECsw) are likely to be in the general range of 40–80 μg L−1 during a pandemic sitaution within urban catchments having low dilution capacities. This implies low risk exposure levels which confirms previous studies, but there are considerable uncertainties associated with the methodology as well as risks that might result from persistent, long term chronic exposure to low-level water and sediment concentrations which might be mobilised under subsequent extreme flow conditions.

Author(s):  
Francesca Mastorci ◽  
Nunzia Linzalone ◽  
Lamia Ait-Ali ◽  
Alessandro Pingitore

In the last few years, many studies have focused on the effects of environmental contaminant exposure during the prenatal period or infancy as predictors of health outcomes in the future. In these time windows, due to their rapid growth, and physiologic and metabolic development, we can observe a higher vulnerability to the effects of environment, with respect to adulthood. The evidence of possible influences, partly mediated by epigenetic mechanisms, involve neurobehavioral responses and immune, endocrine, and respiratory systems, acting directly on the child or indirectly when mediated by placental transfer or breast feeding. In particular, due to a greater intake of air, food, and fluids relative to body weight, crawling behaviors and short stature, the risk of excessive exposure is greater in children. However, data on the long-term implications of early exposures are scarce. Additionally, so that physicians and institutions for child care and assistance of pregnant women can take actions to counteract the effects of chemical pollution (i.e., by educational opportunities), a risk assessment perspective that responds to the biocomplexity of the human being is needed. The present paper provides an overview of physiologic and behavioral characteristics during the perinatal period and in childhood, suggesting in a more integrated way, the need of a new risk-assessment approach to managing chronic disease in pediatric patients.


Think India ◽  
2019 ◽  
Vol 22 (2) ◽  
pp. 296-304
Author(s):  
Biplab Tripathy ◽  
Tanmoy Mondal

India is a subcontinent, there huge no of people lived in river basin area. In India there more or less 80% of people directly or indirectly depend on River. Ganga, Brahamputra in North and North East and Mahanadi, Govabori, Krishna, Kaveri, Narmoda, Tapti, Mahi in South are the major river basin in India. There each year due to flood and high tide lots of people are suffered in river basin region in India. These problems destroy the socio economic peace and hope of the people in river basin. There peoples are continuously suffered by lots of difficulties in sort or in long term basis. Few basin regions are always in high alert at the time of monsoon seasons. Sometime due to over migration from basin area, it becomes empty and creates an ultimate loss of resources in India and causes a dis-balance situation in this area.


2018 ◽  
pp. 149-154

Vera Antonovna Martynenko (17.02.1936–06.01.2018) — famous specialist in the field of studying vascular plant flora and vegetation of the Far North, the Honored worker of the Komi Republic (2006), The Komi Republic State Scientific Award winner (2000). She was born in the town Likhoslavl of the Kali­nin (Tver) region. In 1959, Vera Antonovna graduated from the faculty of soil and biology of the Leningrad State University and then moved to the Komi Branch of USSR Academy of Science (Syktyvkar). From 1969 to 1973 she passed correspondence postgraduate courses of the Komi Branch of USSR Academy of ­Science. In 1974, she received the degree of candidate of biology (PhD) by the theme «Comparative analysis of the boreal flora at the Northeast European USSR» in the Botanical Institute (St. Petersburg). In 1996, Vera Antonovna received the degree of doctor of biology in the Institute of plant and animal ecology (Ekaterinburg) «Flora of the northern and mid subzones of the taiga of the European North-East». The study and conservation of species and coenotical diversity of the plant world, namely the vascular plants flora of the Komi Republic and revealing its transformation under the anthropogenic influence, was in the field of V. A. Martynenko’ scientific interests. She made great contribution to the study of the Komi Republic meadow flora and the pool of medi­cinal plants. She performed inventorying and mapping the meadows of several agricultural enterprises of the Republic, revealed the species composition and places for harvesting medicinal plants and studied their productivity in the natural flora of the boreal zone. The results of her long-term studies were used for making the NPA system and the Red Book of the Komi Republic (1998 and 2009). Vera Antonovna participated in the research of the influence of placer gold mining and oil development on the natural ecosystems of the North, and developed the method of long-term monitoring of plant cover. Results of these works are of high practical value. V. A. Martynenko is an author and coauthor of more than 130 scientific publications. The most important jnes are «Flora of Northeast European USSR» (1974, 1976, and 1977), «Floristic composition of fodder lands of the Northeast Europe» (1989), «The forests of the Komi Republic» (1999), «Forestry of forest resources of the Komi Republic» (2000), «The list of flora of the Yugyd va national park» (2003), «The guide for vascular plants of the Syktyvkar and its vicinities» (2005), «Vascular plants of the Komi Republic» (2008), and «Resources of the natural flora of the Komi Republic» (2014). She also was an author of «Encyclopedia of the Komi Republic» (1997, 1999, and 2000), «Historical and cultural atlas of the Komi Republic» (1997), «Atlas of the Komi Republic» (2001, 2011). V. A. Martynenko made a great contribution to the development of the botanical investigations in the North. Since 1982, during more than 10 years, she was the head of the Department of the Institute of Biology. Three Ph. D. theses have been completed under her leadership. Many years, she worked actively in the Dissertation Council of the Institute of biology Komi Scientific Centre UrB RAS.  The death of Vera Antonovna Martynenko is a heavy and irretrievable loss for the staff of the Institute of Biology. The memory of Vera Antonovna will live in her numerous scientific works, the hearts of students and colleagues.


1983 ◽  
Vol 15 (5) ◽  
pp. 129-135 ◽  
Author(s):  
Z Filip ◽  
K Seidel ◽  
H Dizer

To determine whether long-term sewage treatment can take place without a pollution risk for soil and groundwater, samples from sewage irrigation fields in West Berlin which have been in use since about 1890 were analyzed for enteric viruses and microorganisms. Enteric viruses were detected in only seven samples from a total number of eighty seven taken from different soil depths. With only one exception, no viruses were found below 60 cm. No viruses were detected in groundwater samples. Long-term sewage irrigation did not result in significant changes in the colony courts of aerobic soil bacteria, but the counts of anaerobic bacteria and actinomycetes were slightly elevated and those of microscopic fungi slightly decreased. Potentially pathogenic bacteria were not detected in soil below 90 cm.


1984 ◽  
Vol 16 (8-9) ◽  
pp. 311-325 ◽  
Author(s):  
N B Johansen ◽  
P Harremoës ◽  
M Jensen

Overflow from combined systems constitute an increasing source of pollution of receiving waters, as compared to daily wastewater discharges which undergo treatment to a still higher extent. The receiving water problems from overflows are significant both in a long term scale (mean annual load) and in a short term scale (extreme event load). A method for computation of both annual and extreme load is presented. It is based on historical rain series and the use of a time-area model and simple pollutant mixing model in runoff calculation. Statistical calculations for both mean annual load and extreme events have been applied to the computed overflow series. Based on the computerized method simple manual calculations methods have been developed, resulting in graphs and tables for annual load and extreme load.


2021 ◽  
Vol 285 ◽  
pp. 112029
Author(s):  
Sidney Fernandes Sales Junior ◽  
Camille Ferreira Mannarino ◽  
Daniele Maia Bila ◽  
Cláudio Ernesto Taveira Parente ◽  
Fábio Veríssimo Correia ◽  
...  

2021 ◽  
Vol 190 ◽  
pp. 105319
Author(s):  
Gustavo Machado ◽  
Luis Gustavo Corbellini ◽  
Alba Frias-De-Diego ◽  
Gustavo Nogueira Dieh ◽  
Diego Viali dos Santos ◽  
...  

Author(s):  
Ali Alsaegh ◽  
Elena Belova ◽  
Yuriy Vasil’ev ◽  
Nadezhda Zabroda ◽  
Lyudmila Severova ◽  
...  

The novel coronavirus (COVID-19) outbreak is a public health emergency of international concern, and this emergency led to postponing elective dental care procedures. The postponing aimed to protect the public from an unknown risk caused by COVID-19. At the beginning of the outbreak, for public health authorities, the aerosol-generating procedures and the close proximity between dental care workers and patients in dentistry represented sufficient justification for the delay of dental visits. Dental care is a priority, and for many years, studies have proven that the lack and delay of dental care can cause severe consequences for the oral health of the general population, which can cause a high global burden of oral diseases. Safety is necessary while resuming dental activities, and risk assessment is an efficient method for understanding and preventing the COVID-19 infectious threats facing the dental industry and affecting dental care workers and patients. In this study, for safe dental care delivery, we adapted risk assessment criteria and an approach and an occupational classification system. Based on those tools, we also recommend measures that can help to minimize infectious risk in dental settings.


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