Natural Polymer-based Stimuli-responsive Hydrogels

2020 ◽  
Vol 27 (16) ◽  
pp. 2631-2657 ◽  
Author(s):  
Yuheng Jiang ◽  
Ying Wang ◽  
Qin Li ◽  
Chen Yu ◽  
Wanli Chu
Keyword(s):  
Natural Polymer ◽  
Stimuli Responsive ◽  
Medical Field ◽  
Preparation Methods ◽  
Polymer Hydrogels ◽  
Advanced Technologies ◽  
Redox Responsive ◽  
Good Biocompatibility ◽  
External Stimuli ◽  
Responsive Hydrogels

The abilities of intelligent polymer hydrogels to change their structure and volume phase in response to external stimuli have provided new possibilities for various advanced technologies and great research and application potentials in the medical field. The natural polymer-based hydrogels have the advantages of environment-friendliness, rich sources and good biocompatibility. Based on their responsiveness to external stimuli, the natural polymer-based hydrogels can be classified into the temperature-responsive hydrogel, pH-responsive hydrogel, light-responsive hydrogel, electricresponsive hydrogel, redox-responsive hydrogel, enzyme-responsive hydrogel, magnetic-responsive hydrogel, multi-responsive hydrogel, etc. In this review, we have compiled some recent studies on natural polymer-based stimuli-responsive hydrogels, especially the hydrogels prepared from polysaccharides. The preparation methods, properties and applications of these hydrogels in the medical field are highlighted.

Photothermal-modulated reversible volume transition of wireless hydrogels embedded with redox-responsive carbon dots

2019 ◽  
Vol 7 (11) ◽  
pp. 4800-4812 ◽  
Author(s):  
Pham Thi My Phuong ◽  
Heesauk Jhon ◽  
Insik In ◽  
Sung Young Park
Keyword(s):  
Carbon Dots ◽  
Stimuli Responsive ◽  
Wireless System ◽  
Novel Therapy ◽  
System P ◽  
Volume Transition ◽  
Redox Responsive ◽  
Responsive Hydrogels

The reversible volume transition of redox-responsive hydrogels by NIR has attracted attention as novel therapy for tracking and treating cancer via stimuli-responsive fluorescence on/off with controllable volume transition via wireless system.

scholarly journals Control of the release of functional payloads from redox-responsive nanocapsules

RSC Advances ◽  
2016 ◽  
Vol 6 (106) ◽  
pp. 104330-104337 ◽  
Author(s):  
Shuai Jiang ◽  
Katharina Landfester ◽  
Daniel Crespy
Keyword(s):  
Controlled Release ◽  
Stimuli Responsive ◽  
Redox Responsive ◽  
External Stimuli

Stimuli-responsive nanocontainers allow for storage and controlled release of functional payloads in response to external stimuli.

A simple strategy for robust preparation and characterisation of hydrogels derived from chitosan and amino functional monomers for biomedical applications

2018 ◽  
Vol 6 (31) ◽  
pp. 5115-5129 ◽  
Author(s):  
Ferdous Khan ◽  
Fumihiro Aratsu ◽  
Shingo Kobayashi ◽  
Masaru Tanaka
Keyword(s):  
Molecular Interactions ◽  
Biomedical Applications ◽  
Stimuli Responsive ◽  
Functional Monomers ◽  
Simple Strategy ◽  
External Stimuli ◽  
Responsive Hydrogels

Molecular interactions of amino functional (AF) monomers with chitosan (CS) lead to the formation of external stimuli responsive hydrogels (HGs).

Smart Polymers and their Applications: A Review

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Gore S. A. ◽  
Gholve S. B. ◽  
Savalsure S. M. ◽  
Ghodake K. B. ◽  
Bhusnure O. G. ◽  
...  
Keyword(s):  
Oil Recovery ◽  
Water Soluble ◽  
Solution Temperature ◽  
Smart Polymers ◽  
Stimuli Responsive ◽  
Responsive Materials ◽  
Water Soluble Polymers ◽  
Commercial Applications ◽  
Stimuli Sensitive ◽  
External Stimuli

Smart polymers are materials that respond to small external stimuli. These are also referred as stimuli responsive materials or intelligent materials. Smart polymers that can exhibit stimuli-sensitive properties are becoming important in many commercial applications. These polymers can change shape, strength and pore size based on external factors such as temperature, pH and stress. The stimuli include salt, UV irradiation, temperature, pH, magnetic or electric field, ionic factors etc. Smart polymers are very promising applicants in drug delivery, tissue engineering, cell culture, gene carriers, textile engineering, oil recovery, radioactive wastage and protein purification. The study is focused on the entire features of smart polymers and their most recent and relevant applications. Water soluble polymers with tunable lower critical solution temperature (LCST) are of increasing interest for biological applications such as cell patterning, smart drug release, DNA sequencing etc.

Sticky ends in a self-assembling ABA triblock copolymer: the role of ureas in stimuli-responsive hydrogels

2019 ◽  
Vol 4 (1) ◽  
pp. 91-102 ◽  
Author(s):  
Ryan T. Shafranek ◽  
Joel D. Leger ◽  
Song Zhang ◽  
Munira Khalil ◽  
Xiaodan Gu ◽  
...  
Keyword(s):  
Self Assembly ◽  
Viscoelastic Properties ◽  
Triblock Copolymer ◽  
Thermal Response ◽  
Stimuli Responsive ◽  
Self Assembling ◽  
Polymeric Hydrogels ◽  
Aba Triblock Copolymer ◽  
Responsive Hydrogels

Directed self-assembly in polymeric hydrogels allows tunability of thermal response and viscoelastic properties.

scholarly journals Dynamic Manipulation of THz Waves Enabled by Phase-Transition VO2 Thin Film

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 114
Author(s):  
Chang Lu ◽  
Qingjian Lu ◽  
Min Gao ◽  
Yuan Lin
Keyword(s):  
Optical Methods ◽  
Stimuli Responsive ◽  
Device Structure ◽  
Current State ◽  
Insulator Metal Transition ◽  
Potential Applications ◽  
Fs Laser ◽  
External Stimuli ◽  
Thz Applications ◽  
Thz Waves

The reversible and multi-stimuli responsive insulator-metal transition of VO2, which enables dynamic modulation over the terahertz (THz) regime, has attracted plenty of attention for its potential applications in versatile active THz devices. Moreover, the investigation into the growth mechanism of VO2 films has led to improved film processing, more capable modulation and enhanced device compatibility into diverse THz applications. THz devices with VO2 as the key components exhibit remarkable response to external stimuli, which is not only applicable in THz modulators but also in rewritable optical memories by virtue of the intrinsic hysteresis behaviour of VO2. Depending on the predesigned device structure, the insulator-metal transition (IMT) of VO2 component can be controlled through thermal, electrical or optical methods. Recent research has paid special attention to the ultrafast modulation phenomenon observed in the photoinduced IMT, enabled by an intense femtosecond laser (fs laser) which supports “quasi-simultaneous” IMT within 1 ps. This progress report reviews the current state of the field, focusing on the material nature that gives rise to the modulation-allowed IMT for THz applications. An overview is presented of numerous IMT stimuli approaches with special emphasis on the underlying physical mechanisms. Subsequently, active manipulation of THz waves through pure VO2 film and VO2 hybrid metamaterials is surveyed, highlighting that VO2 can provide active modulation for a wide variety of applications. Finally, the common characteristics and future development directions of VO2-based tuneable THz devices are discussed.

scholarly journals Combining Dextran Conjugates with Stimuli-Responsive and Folate-Targeting Activity: A New Class of Multifunctional Nanoparticles for Cancer Therapy

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1108
Author(s):  
Manuela Curcio ◽  
Alessandro Paolì ◽  
Giuseppe Cirillo ◽  
Sebastiano Di Pietro ◽  
Martina Forestiero ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Metastatic Cancer ◽  
Stimuli Responsive ◽  
Cancer Disease ◽  
New Class ◽  
Self Assembling ◽  
Redox Responsive ◽  
Potential Applicability ◽  
Mean Size

Nanoparticles with active-targeting and stimuli-responsive behavior are a promising class of engineered materials able to recognize the site of cancer disease, targeting the drug release and limiting side effects in the healthy organs. In this work, new dual pH/redox-responsive nanoparticles with affinity for folate receptors were prepared by the combination of two amphiphilic dextran (DEX) derivatives. DEXFA conjugate was obtained by covalent coupling of the polysaccharide with folic acid (FA), whereas DEXssPEGCOOH derived from a reductive amination step of DEX was followed by condensation with polyethylene glycol 600. After self-assembling, nanoparticles with a mean size of 50 nm, able to be destabilized in acidic pH and reducing media, were obtained. Doxorubicin was loaded during the self-assembling process, and the release experiments showed the ability of the proposed system to modulate the drug release in response to different pH and redox conditions. Finally, the viability and uptake experiments on healthy (MCF-10A) and metastatic cancer (MDA-MB-231) cells proved the potential applicability of the proposed system as a new drug vector in cancer therapy.

scholarly journals Metal-Organic Framework-Based Stimuli-Responsive Polymers

2021 ◽  
Vol 5 (4) ◽  
pp. 101
Author(s):  
Menglian Wei ◽  
Yu Wan ◽  
Xueji Zhang
Keyword(s):  
Metal Organic Framework ◽  
Chemical Properties ◽  
Stimuli Responsive ◽  
Guest Molecules ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Reversible Phase Transition ◽  
Metal Organic ◽  
External Stimuli ◽  
Organic Framework

Metal-organic framework (MOF) based stimuli-responsive polymers (coordination polymers) exhibit reversible phase-transition behavior and demonstrate attractive properties that are capable of altering physical and/or chemical properties upon exposure to external stimuli, including pH, temperature, ions, etc., in a dynamic fashion. Thus, their conformational change can be imitated by the adsorption/desorption of target analytes (guest molecules), temperature or pressure changes, and electromagnetic field manipulation. MOF-based stimuli responsive polymers have received great attention due to their advanced optical properties and variety of applications. Herein, we summarized some recent progress on MOF-based stimuli-responsive polymers (SRPs) classified by physical and chemical responsiveness, including temperature, pressure, electricity, pH, metal ions, gases, alcohol and multi-targets.

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