Electrochemical and Electrochemiluminescence Dendrimer-based Nanostructured Immunosensors for Tumor Marker Detection: A review

2020 ◽  
Vol 27 ◽  
Author(s):  
Hayati Filik ◽  
Asiye Aslıhan Avan
Keyword(s):  
Quantum Dots ◽  
Mortality Rate ◽  
Tumor Marker ◽  
Metal Nanoparticles ◽  
Magnetic Particles ◽  
Clinical Applications ◽  
Cancer Markers ◽  
Recent Advances ◽  
Marker Detection

: The usage of dendrimers or cascade molecules in the biomedical area can be recently attracted much attention worldwide. Also, dendrimers are interesting in the field of clinical and pre-clinical applications due to their unique characteristics. Cancer is one of the most widespread challenges and important diseases, which has the highest mortality rate. In this review, the recent advances and developments (from 2009 up to 2019) in the field of electrochemical and electroluminescence immunosensors for detection of the cancer markers are presented. Also, this review covers the basic fabrication principles and types of electrochemical and electrochemiluminescence dendrimer-based immunosensors. In this review, we categorized the current dendrimer based-electrochemical/electroluminescence immunosensors into five groups, dendrimer/magnetic particles, dendrimer/ferrocene, dendrimer/metal nanoparticles, thiol-containing dendrimer and dendrimer/quantum dots based-immunosensors.

Trends in Nanotechnology for in vivo Cancer Diagnosis: Products and Patents

2020 ◽  
Vol 26 (18) ◽  
pp. 2167-2181
Author(s):  
Tatielle do Nascimento ◽  
Melanie Tavares ◽  
Mariana S.S.B. Monteiro ◽  
Ralph Santos-Oliveira ◽  
Adriane R. Todeschini ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Quantum Dots ◽  
Magnetic Resonance ◽  
Metal Nanoparticles ◽  
Cancer Diagnosis ◽  
Imaging Techniques ◽  
Tumor Detection ◽  
Abnormal Growth ◽  
Pharmaceutical Nanotechnology

Background: Cancer is a set of diseases formed by abnormal growth of cells leading to the formation of the tumor. The diagnosis can be made through symptoms’ evaluation or imaging tests, however, the techniques are limited and the tumor detection may be late. Thus, pharmaceutical nanotechnology has emerged to optimize the cancer diagnosis through nanostructured contrast agent’s development. Objective: This review aims to identify commercialized nanomedicines and patents for cancer diagnosis. Methods: The databases used for scientific articles research were Pubmed, Science Direct, Scielo and Lilacs. Research on companies’ websites and articles for the recognition of commercial nanomedicines was performed. The Derwent tool was applied for patent research. Results: This article aimed to research on nanosystems based on nanoparticles, dendrimers, liposomes, composites and quantum dots, associated to imaging techniques. Commercialized products based on metal and composite nanoparticles, associated with magnetic resonance and computed tomography, have been observed. The research conducted through Derwent tool displayed a small number of patents using nanotechnology for cancer diagnosis. Among these patents, the most significant number was related to the use of systems based on metal nanoparticles, composites and quantum dots. Conclusion: Although few systems are found in the market and patented, nanotechnology appears as a promising field for the development of new nanosystems in order to optimize and accelerate the cancer diagnosis.

scholarly journals Quick extracellular biosynthesis of low-cadmium ZnxCd1−xS quantum dots with full-visible-region tuneable high fluorescence and its application potential assessment in cell imaging

RSC Advances ◽  
2021 ◽  
Vol 11 (35) ◽  
pp. 21813-21823
Author(s):  
Shiyue Qi ◽  
Ji Chen ◽  
Xianwei Bai ◽  
Yahui Miao ◽  
Shuhui Yang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Energy Saving ◽  
Metal Nanoparticles ◽  
Cell Imaging ◽  
Visible Region ◽  
Extracellular Biosynthesis ◽  
Application Potential ◽  
Good Biocompatibility ◽  
High Fluorescence ◽  
Environmentally Sound

The biosynthesis of metal nanoparticles/QDs has been universally recognized as environmentally sound and energy-saving, generating less pollution and having good biocompatibility, which is most needed in biological and medical fields.

Tumor Marker Detection by Aptamer-Functionalized Graphene Oxide

2013 ◽  
Vol 17 (2) ◽  
pp. 132-136 ◽  
Author(s):  
Ming-Yu Lin ◽  
Yen-Pei Lu ◽  
Alexandru Grumezescu ◽  
Fu Han Ho ◽  
Ying-Hsien Kao ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Tumor Marker ◽  
Functionalized Graphene ◽  
Functionalized Graphene Oxide ◽  
Marker Detection

Fluorescence immunosensor based on p-acid-encapsulated silica nanoparticles for tumor marker detection

The Analyst ◽  
2012 ◽  
Vol 137 (12) ◽  
pp. 2834 ◽  
Author(s):  
Mei Yan ◽  
Shenguang Ge ◽  
Weiqiang Gao ◽  
Chengchao Chu ◽  
Jinghua Yu ◽  
...  
Keyword(s):  
Tumor Marker ◽  
Silica Nanoparticles ◽  
Marker Detection
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