Direct Synthesis of Aromatic Imine Schiff Bases from β-Phenol Hydroxy Ketone
Keyword(s):
: A facile methodology has been developed to build carbon nitrogen double bond from ketones promoted by the hydroxyl groups in β-phenol hydroxy ketone. It is noteworthy that the halogenated β-phenol hydroxy ketone can chemoselectively react with amine to afford halogenated phenol imine. It is suitable for certain natural products and also suitable for water-based heteroamines. The method is low toxicity, widely applicable. This strategy is usually used to obtain moderate to good yields of aromatic amine Schiff base.
2020 ◽
Vol 23
(2)
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pp. 111-118
1990 ◽
Vol 55
(12)
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pp. 2874-2879
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1962 ◽
Vol 3
(26)
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pp. 1269-1274
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