A case of Postpartum Maternal death with COVID-19 in the west of Iran

2020 ◽  
Vol 17 ◽  
Author(s):  
Maryam Ahmadi ◽  
Mehrangiz Zamani Bonab ◽  
Sorour Akbari ◽  
Hamideh Parsapour ◽  
Shohreh Alimohammadi ◽  
...  

Introduction:: There are a limited number of studies about COVID-19 during delivery and postpartum. Case presentation:: A 38 -years- old G3p2 woman at 35 weeks and 4 days of gestation was referred with the chief complaints of dyspnea, cough, headache, and fever. Pharyngeal swab polymerase chain reaction (PCR) was negative for COVID-19; however, in chest computed tomography (CT) angiography, ground glass was observed in the basal lobe of the left lung. The infant was born via cesarean section with a gestational age of 36 weeks and an Apgar score of 8/9. No infant document was found about COVID-19 and other infections in several days after delivery. The patient died eight days after the onset of symptoms due to cardiovascular collapse. Discussion:: we reported the first death of a postpartum maternal with COVID-19 and a healthy baby with no evidence of COVID-19 and a gestational age of 36 weeks. Conclusion:: Physicians should be aware that pregnant women with symptoms of respiratory infection and pulse negative PCR test should be followed for infected with COVID-19. This infection may be led to maternal death.

2020 ◽  
Author(s):  
Maryam Ahmadi ◽  
Mehrangiz Zamani bonab ◽  
Sorour Akbari ◽  
Hamideh parsapour ◽  
Shohreh Alimohammadi ◽  
...  

Abstract Background: There are a limited number of studies about COVID-19 during delivery and postpartum.Case presentation: A 38-years old G3p2 woman at 35 weeks and 4 days of gestation referred with the chief complaints of dyspnea, cough, headache, and fever. Pharyngeal swab polymerase chain reaction (PCR) was negative for COVID-19; however, in chest computed tomography (CT) angiography, ground glass was observed in the basal lobe of the left lung. The infant was born via cesarean section with gestational age of 36 weeks and an Apgar score of 8/9. No infant document was found about COVID-19‎ and other infections in several days after delivery. The patient died eight days after the onset of symptoms due to cardiovascular collapse.Conclusions: We reported the first death of postpartum maternal with COVID-19 and a healthy baby with no evidence of COVID-19 and gestational age of 36 weeks.


2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Felix S. Seibert ◽  
Daniela Toma ◽  
Frederic Bauer ◽  
Krystallenia Paniskaki ◽  
Moritz Anft ◽  
...  

Abstract Background Developing therapeutic strategies for a SARS-CoV-2 infection is challenging, but first the correct diagnosis has to be made. Unspecific upper and lower respiratory tract symptoms can be misleading; hence, a nasopharyngeal swab test with a real-time reverse-transcription-polymerase chain reaction is of great importance. However, early viral clearing jeopardizes a sound diagnosis of COVID-19. Case presentation We report on two Caucasian patients who had negative pharyngeal swab tests at the onset of SARS-CoV-2 pneumonia. In one patient, the virus was not even detectable in bronchoalveolar lavage despite typical radiomorphologic changes. Conclusions Negative PCR findings in both the pharynx and bronchoalveolar lavage do not exclude COVID-19 pneumonia. Computed tomography is a crucial diagnostic prerequisite in this context.


Author(s):  
Diana Massalska ◽  
Katarzyna Ozdarska ◽  
Tomasz Roszkowski ◽  
Julia Bijok ◽  
Anna Kucińska-Chahwan ◽  
...  

Abstract Purpose To establish the distribution of diandric and digynic triploidy depending on gestational age. Methods 107 triploid samples tested prospectively in a single genetic department during a four-year period were analyzed for parental origin of triploidy by Quantitative Fluorescent Polymerase Chain Reaction (QF-PCR) (n=95) with the use of matching parental samples or by MS-MLPA (n=12), when parental samples were unavailable. Tested pregnancies were divided into three subgroups with regard to the gestational age at spontaneous pregnancy loss: <11 gestational weeks, 11–14 gestational weeks, and >14 gestational weeks. Results Diandric triploidy constituted overall 44.9% (46.5% in samples miscarried <11 gestational weeks, 64.3% in samples miscarried between 11 and 14 gestational weeks, and 27.8% in pregnancies which survived >14 gestational weeks). Conclusions The distribution of diandric and digynic triploidy depends on gestational age. The majority of diandric triploid pregnancies is lost in the first trimester of pregnancy. In the second trimester, diandric cases are at least twice less frequent than digynic ones.


2020 ◽  
Vol 49 (6) ◽  
pp. 761-764 ◽  
Author(s):  
Hai Yuan ◽  
E. Guo ◽  
Zhao Gao ◽  
Fengqi Hu ◽  
Li Lu

There has been a global outbreak of the coronavirus disease 2019 (COVID-19) since December 2019. Here, we describe the case of a 49-year-old male undergoing maintenance hemodialysis (HD) who got infected with COVID-19 and our experience in performing HD for him. The patient’s symptoms and lung imaging changes were atypical. However, his lymphocyte range decreased upon admission and the polymerase chain reaction of the pharyngeal swab for the ­COVID-19 nucleic acid was positive. The patient developed respiratory failure and required mechanical ventilation 8 days after admission. In the end, he died from multiple organ dysfunction syndrome. The difficulties in diagnosis, infection control, and treatment of COVID-19 in maintenance HD patients are discussed in this report.


2019 ◽  
Vol 7 (19) ◽  
pp. 3262-3264
Author(s):  
Taher Felemban ◽  
Abdullah Ashi ◽  
Abdullah Sindi ◽  
Mohannad Rajab ◽  
Zuhair Al Jehani

BACKGROUND: Having hoarseness of voice as the first clinical manifestation of tuberculosis is rare. This atypical presentation causes some confusion since other more common conditions, such as laryngeal carcinoma, present similarly and might require more invasive tests to confirm the diagnosis. CASE PRESENTATION: A 38-year-old male presented to the otorhinolaryngology clinic with a four-month history of change in voice. Laryngoscopy demonstrated a right glottic mass, raising suspicion of laryngeal cancer. The computed tomography showed a mass and incidental finding of opacities in lung apices. Chest x-ray demonstrated findings suggestive of tuberculosis. Polymerase chain reaction and culture of sputum samples confirmed the diagnosis and the patient was started on anti-tuberculosis treatment. CONCLUSION: Despite accounting for only 1% of pulmonary tuberculosis cases and having a similar presentation to laryngeal carcinoma, we recommend considering laryngeal tuberculosis when evaluating hoarseness of voice in endemic areas.


Author(s):  
Tugba Erat ◽  
Müge Atar ◽  
Tugba Kontbay

AbstractObjectivesCoronavirus disease (COVID-19) rapidly spread worldwide in a few months and was declared as a worldwide pandemic by WHO in March 2020. Transient benign hyperphosphatasemia (THI) is a benign condition associated with marked elevation of alkaline phosphatase (ALP) without any other kidney, bone, and liver pathologies.Case presentationHerein, we report a previously healthy 16-month-old female patient who developed a secondary transient benign hyperphosphatasemia associated with SARS-CoV-2. Patient whole family’s SARS-CoV-2 real-time reverse transcription-polymerase chain reaction (RT-PCR) results were positive. Since THI is a diagnosis of exclusion, other reasons that may cause ALP elevation should be ruled out. ALP activity decreased and turned to normal ranges within the following month. THI has been reported to be in association with various conditions. Its relationship with many viruses has been reported previously.ConclusionsIf ALP elevation is detected in patients with COVID 19 due to the increasing number of infections, THI should be considered if there is no other accompanying pathology.


2021 ◽  
Vol 8 (1) ◽  
pp. 75-77
Author(s):  
Ambika Nand Jha ◽  
Akshay H Shah ◽  
Upama N Trivedi

SARS-COV 2 Is causative agent of COVID 19, just few month ago was foreign to us and now spreading its routes well in India. Starting with one case As of August 25, 2020 in India 3167323 positive cases have been reported. coronavirus is beta form  of SARS-CoV-2 belong to family of Coronaviridae. A 44-year-old man, who lives in Kolakata, West Bengal, Working in a travel agency. He came To OPD with complaint of fever, Throat Infection, Multiple joint and muscle pain, Cough. A SARS-CoV-2 Reverse transcriptase polymerase chain reaction (RTPCR) test was positive. He was being treated & Monitored in Home isolation with high dose oral ascorbic acid, hydroxychloroquine, azithromycin and Zinc acetate. This Article aimed to Case Presentation And Treatment Review of Novel COVID 19. Journal of Current and Advance Medical Research, January 2021;8(1):75-77


2020 ◽  
Vol 8 (3) ◽  
Author(s):  
Reza Amiraskari ◽  
Elaheh Sayarifard ◽  
Hamed Kharrazi ◽  
Neda Naserfar ◽  
Azadeh Sayarifard

Introduction: With the outbreak of coronavirus 2019 (SARS-COV-2), the prevention and control of SARS-COV-2 infection in pregnant women and the potential risk of vertical transmission has become a major concern. Case Presentation: We report the case of a newborn in Iran with the manifestations of myocarditis at birth. The diagnosis of SARS-COV-2 infection was confirmed for the mother and the neonate by real-time reverse transcription polymerase chain reaction (rRT-PCR) using a pharyngeal specimen. Conclusions: Based on our literature review, there is still insufficient evidence to determine the effect of SARS-COV-2 infection on the fetus. Given the possibility of cardiac injury in SARS-COV-2 disease and manifestation of congenital myocarditis in our case, maternal vertical transmission of SARS-COV-2 could be considered.


2021 ◽  
Vol 18 (3) ◽  
Author(s):  
Kazem Ghaemi ◽  
Tahereh Darvishpour Kakhki ◽  
Fatemeh Abbasi ◽  
Malihe Nikandish

Introduction: Coronavirus disease 2019 (COVID-19) has emerged as a pandemic and is accompanied by extraordinary morbidity and mortality. Critically ill COVID-19 patients have frequent thrombotic problems and laboratory evidence of hypercoagulability. The spectrum of presentations and complications of COVID-19 is still evolving. We describe a patient with unusual visual symptoms as the presenting signs of COVID-19. Case Presentation: In this case report, we describe a patient who presented with acute severe bilateral visual loss and headache. On neurological examination, cranial nerves were normal. There was no motor and sensorial abnormality. While the patient was in the emergency room, he was tested positive for COVID-19 via nasopharyngeal swab polymerase chain reaction (PCR) as part of COVID-19 surveillance. An unenhanced brain CT scan showed infarction in the occipital cortex bilaterally due to ischemic stroke involving the Posterior Cerebral Artery (PCA). A few hours later, oxygen saturation was 42%, and a sudden decline of consciousness was observed, progressing to coma. The neurosurgery intervention failed to change the patient's status, and he was pronounced dead in the next few hours. Conclusions: This case illuminates a wide range of COVID-19-related symptomatology and highlights the need for clinicians to be aware of different clinical appearances associated with this infection.


2020 ◽  
Author(s):  
Abhijeet Singh ◽  
Ayush Gupta ◽  
Kamanashish Das

Abstract Background: The ongoing pandemic of novel coronavirus disease 2019 (COVID-19) has received worldwide attention by becoming a major global health threat. We encountered one case with COVID-19 and tuberculosis (TB) coinfection which has not been frequently reported. Case presentation: A 76 year old female presented with acute respiratory symptoms superimposed on chronic symptoms, suggestive to have pneumonia. Oropharyngeal throat swab sample for COVID-19 was positive as detected by real-time reverse-transcriptase–polymerase-chain-reaction (RT-PCR) assay. GeneXpert Ultra detected Mycobacterium tuberculosis complex with Rifampicin resistance indeterminate. Patient was treated with appropriate management. Conclusion: Clinicians should suspect coinfection with TB during ongoing pandemic of COVID-19 as therapeutic strategies need to be determined timely to improve outcome and prevent transmission in community.


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