scholarly journals A Micro-fluidic System for the Evaluation of Blood Compatibility of Polymers

2008 ◽  
Vol 2 (1) ◽  
pp. 43-50 ◽  
Author(s):  
C. Minelli ◽  
A. Kikuta ◽  
A. Yamamoto

We present a new technique for the evaluation of polymer blood compatibility that makes use of a microchannel array flow analyzer and we describe and characterize the flow dynamics of this instrument. The blood compatibility of four polymers is quantitatively and qualitatively assessed and the results discussed. The blood is allowed to flow through the channels of a polymer coated micro-fluidic chip under adjustable pressure. The chip surface is investigated using optical microscopy during the blood flow and by scanning electron microscopy afterwards. Polymers known for having good blood compatibility exhibited higher flow rate values. Platelets were observed adhering, aggregating and obstructing the channels of the chips coated with polymers known for having poor blood compatibility. This technique has remarkable qualities such as a small blood volume requirement for material tests (100 μL), tuneable flow regimes and the use of human blood.

Author(s):  
Brian Savilonis ◽  
Kalen Smith

Understanding of the transnasal pressure and flow behavior during normal breathing conditions has been a subject of much discussion and research. In particular we are interested in testing the hypothesis of quasi-steady flow as well as the role of turbulence on nasal flow dynamics.


2010 ◽  
Vol 434-435 ◽  
pp. 814-815
Author(s):  
An Ran Guo ◽  
Jia Chen Liu ◽  
Yi Bing Sun ◽  
Wen Jun Lian ◽  
Lu Yang

A new technique of flyash utilization was presented and high-purity silica was prepared by alkali leaching. The flyash was added into sodium hydroxide solution, and then the suspension was heated to 115 °C for 30 min. After filtrated, the filtrate was collected and carbon dioxide was imported into the solution. Finally, the silica would precipitate from the solution. The silica was characterized by scanning electron microscopy, X-ray diffraction and X-ray fluorescence spectrometer. The high-purity silica prepared from flyash was qualified for the rubber reinforcing agent used in shoemaking.


2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Tanja Eichhorn ◽  
Alexander E. Ivanov ◽  
Maria B. Dainiak ◽  
André Leistner ◽  
Ingrid Linsberger ◽  
...  

Composite monolithic adsorbents were prepared by the incorporation of neutral polystyrene divinylbenzene (PS-DVB) microparticles into macroporous polymer structures produced by cryogelation of agarose or poly(vinyl alcohol). The composite materials exhibited excellent flow-through properties. Scanning electron microscopy of the composite cryogels revealed that the microparticles were covered by thin films of poly(vinyl alcohol) or agarose and thus were withheld in the monolith structure. Plain PS-DVB microparticles showed efficient adsorption of albumin-bound toxins related to liver failure (bilirubin and cholic acid) and of cytokines (tumor necrosis factor-alpha and interleukin-6). The rates of adsorption and the amount of adsorbed factors were lower for the embedded microparticles as compared to the parent PS-DVB microparticles, indicating the importance of the accessibility of the adsorbent pores. Still, the macroporous composite materials showed efficient adsorption of albumin-bound toxins related to liver failure as well as efficient binding of cytokines, combined with good blood compatibility. Thus, the incorporation of microparticles into macroporous polymer structures may provide an option for the development of adsorption modules for extracorporeal blood purification.


1988 ◽  
Vol 7 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Liam T. Gallagher

Abstract. A new technique for viewing the same nannofossil specimen under the light microscope and scanning electron microscope is described, in which standard preparation materials are used. The applications of this, and previous techniques, are discussed as well as the relevance of these to the elucidation of taxonomic problems.


2012 ◽  
Vol 27 (4) ◽  
pp. 295-312 ◽  
Author(s):  
Mariangela Fedel ◽  
Tugba Endogan ◽  
Nesrin Hasirci ◽  
Devid Maniglio ◽  
Andrea Morelli ◽  
...  

2010 ◽  
Vol 146-147 ◽  
pp. 1788-1791 ◽  
Author(s):  
Song Yang Zhang ◽  
Xiao Qin Guo ◽  
Chang Hong Liu ◽  
Si Zhong Li ◽  
Ying Zhang

There are many advantages of semi-solid processing technology such as energy saving, high efficiency and net-shaped processing. So it is a promising manufacturing technology in 21 century .It is the premise of getting the non-dendrite semisolid slurry to realize the semisolid processing.This paper reviewed the development of the technique of preparation for semi-solid state slurry and introduced some new researchment about the technique of preparation slurry for semi-solid processing. It researched a new technique of preparation for semi-solid state slurry—cooling by the sine function to produced the semi-solid state slurry. The result showed that the aluminum alloy melt was cooled and controlled nucleation and limited growth in the sine wave The fundamental principles through which sound semi-solid slurry can be effectively obtained were summarized.On the basis of the experiment and simulation,it analysised the temperature field and the flow field of the semisolid 2A12 slurry flow through sine passage. The result showed that there is the cooling and the self-stirring when the semisolid 2A12 slurry flow through sine passage. The fundamental principles through which sound semi-solid slurry can be effectively obtained were summarized. Finally, we presented a patent this simple process .


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