scholarly journals VODAN BR: a gestão de dados no enfrentamento da pandemia coronavírus

2020 ◽  
pp. 51-58
Author(s):  
Viviane Veiga ◽  
Maria Luiza Campos ◽  
Carlos Roberto Lyra da Silva ◽  
Patrícia Henning ◽  
João Moreira
Keyword(s):  
Infectious Disease ◽  
Medical Records ◽  
Albert Einstein ◽  
Patient Records ◽  
International Network ◽  
Data Network ◽  
Data Infrastructure ◽  
The World ◽  
Fair Principles ◽  
National Infrastructure

The world is experiencing a pandemic caused by the variant of the Coronavirus named SARS-CoV-2, causing the infectious disease COVID-19. Global actions are being carried out to combat this virus, including the Virus Outbreak Data Network (VODAN), which aims to establish a federated data infrastructure aligned with the FAIR principles and which supports the data collect from medical records of patients infected with high contagion. FIOCRUZ, which coordinates the GO FAIR Brazil Health network, took over the VODAN BR network in partnership with UNIRIO and UFRJ, with the participation of the hospitals Gaffrée and Guinle, Municipal São José and Israelita Albert Einstein. This article aims to present the national infrastructure aligned with the guidelines and the international network, for collecting and managing data from patient records, of these hospitals, infected with COVID-19, to establish an information model that supports the confrontation of this and other possible pandemics.

scholarly journals Automatic BIRCH thresholding with features transformation for hierarchical breast cancer clustering

2022 ◽  
Vol 12 (2) ◽  
pp. 1498
Author(s):  
Ahmad Alzu'bi ◽  
Maysarah Barham
Keyword(s):  
Breast Cancer ◽  
Medical Records ◽  
Breast Screening ◽  
Similarity Measures ◽  
Experimental Results ◽  
Optimal Threshold ◽  
Patient Records ◽  
Performance Impact ◽  
The World ◽  
The Subject

<p>Breast cancer is one of the most common diseases diagnosed in women over the world. The balanced iterative reducing and clustering using hierarchies (BIRCH) has been widely used in many applications. However, clustering the patient records and selecting an optimal threshold for the hierarchical clusters still a challenging task. In addition, the existing BIRCH is sensitive to the order of data records and influenced by many numerical and functional parameters. Therefore, this paper proposes a unique BIRCH-based algorithm for breast cancer clustering. We aim at transforming the medical records using the breast screening features into sub-clusters to group the subject cases into malignant or benign clusters. The basic BIRCH clustering is firstly fed by a set of normalized features then we automate the threshold initialization to enhance the tree-based sub-clustering procedure. Additionally, we present a thorough analysis on the performance impact of tuning BIRCH with various relevant linkage functions and similarity measures. Two datasets of the standard breast cancer wisconsin (BCW) benchmarking collection are used to evaluate our algorithm. The experimental results show a clustering accuracy of 97.7% in 0.0004 seconds only, thereby confirming the efficiency of the proposed method in clustering the patient records and making timely decisions.</p>

Designing an Outer Membrane Protein (Omp-W) Based Vaccine for Immunization against Vibrio and Salmonella: An in silico Approach

2020 ◽  
Vol 14 (4) ◽  
pp. 312-324
Author(s):  
Sadra S. Tehrani ◽  
Abolfazl Jahangiri ◽  
Mortaza Taheri-Anganeh ◽  
Hossein Maghsoudi ◽  
Saeed Khalili ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Vibrio Cholerae ◽  
Gram Negative Bacteria ◽  
B Cell Epitopes ◽  
E Coli ◽  
Beta Barrel ◽  
The World ◽  
Cd4 Cell ◽  
Stimulating Factor ◽  
Topology Prediction

Background: Cholera triggered by Vibrio cholerae remains the main reason for morbidity and mortality all over the world. In addition, salmonellosis is regarded as an infectious disease that makes it essential for the identification and detection of Salmonella. With a beta-barrel structure consisting of eight non-parallel beta strands, OmpW family is widely distributed among gram-negative bacteria. Moreover, OmpW isolated from S. typhimurium and Vibrio cholerae can be used in vaccine design. Methods: Topology prediction was determined. T-cell and B-cell epitopes were selected from exposed areas, and sequence conservancy was evaluated. The remaining loops and inaccessible residues were removed to prepare OmpW-1. High antigenicity peptides were detected to replace inappropriate residues to obtain OmpW-2. Physicochemical properties were assessed, and antigenicity, hydrophobicity, flexibility, and accessibility were compared to the native Omp-W structure. Low score areas were removed from the designed structure for preparing the OmpW-3. To construct OmpW-4, TTFrC was used as T-CD4+ cell-stimulating factor and CTB as adjuvant to the end of the C-terminal of this sequence, which can increase the antigenicity and sequence density. The sequences were re-analyzed to delete the unfavorable residues. Besides, the solubility of the mature OmpW and the designed structure were predicted while overexpressed in E. coli. Results: The designed vaccine is a stable protein which has immune cells recognizing epitopes and is considered as an antigen. The construct can be overexpressed in a E. coli. Conclusion: The multi-epitope vaccine is a suitable stimulator for immune system and would be a candidate for experimental research. Recent patents describing numerous inventions related to the clinical facets of vaccine peptide against human infectious disease.

Rice tablet (Aluminum Phosphide) poisoning

2016 ◽  
Vol 5 (11) ◽  
pp. 5041
Author(s):  
Farkhondeh Jamshidi ◽  
Ahmad Ghorbani ◽  
Sina Darvishi*
Keyword(s):  
Medical Records ◽  
Statistical Tests ◽  
Patient Records ◽  
Demographic Information ◽  
Aluminum Phosphide ◽  
Men And Women ◽  
Significant Difference ◽  
The Mean ◽  
Aluminum Phosphide Poisoning ◽  
Commit Suicide

The abuse of some pesticides especially to suicide is one of the current problems of pesticides. Aluminum phosphide induced poisoning usually happens to suicide and sometimes it is due to accidental occupational exposure and in a few cases it has some criminal intensions. This study is conducted to evaluate patients poisoned with aluminum phosphide. In the present study the medical records of cases of poisoning with rice tablets (aluminum phosphide) hospitalized in Ahvaz Razi hospital is studied. Accordingly, a checklist is prepared that included demographic information of patients (age, gender) and information on patient records (information on poisoning) are completed using the patients’ medical records. The analysis of data is done by SPSS V22. 18 patients poisoned with rice tablet (aluminum phosphide) are studied. Results of the study show that 11 patients are male and seven are female. The mean patient age is 27.06 ±8.04 years that is 28 ±9 and 25 ±6.02 in men and women respectively. Statistical tests show no statistically significant difference in mean age in both genders (P> 0.05). Among patients, 11 subjects took aluminum phosphide to attempt suicide and 3 cases took it unintentionally and of course the reason is not mentioned in four cases. Among the patients who tried to commit suicide by taking aluminum phosphide, 6 cases are male and 5 cases are female that no statistically significant difference is observed between the genders in this respect (P> 0.05). In addition to the study of the complications caused by this poisoning and its mortality, it is recommended to responsible authorities to provide the necessary educations and treatments to prevent this type of poisoning.

scholarly journals Infectious disease outbreaks in the African region: overview of events reported to the World Health Organization in 2018

2019 ◽  
Vol 147 ◽  
Author(s):  
F. Mboussou ◽  
P. Ndumbi ◽  
R. Ngom ◽  
Z. Kassamali ◽  
O. Ogundiran ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Disease Onset ◽  
Disease Outbreaks ◽  
Case Fatality ◽  
World Health ◽  
African Region ◽  
Regional Office ◽  
Member States ◽  
Infectious Disease Outbreaks ◽  
The World

Abstract The WHO African region is characterised by the largest infectious disease burden in the world. We conducted a retrospective descriptive analysis using records of all infectious disease outbreaks formally reported to the WHO in 2018 by Member States of the African region. We analysed the spatio-temporal distribution, the notification delay as well as the morbidity and mortality associated with these outbreaks. In 2018, 96 new disease outbreaks were reported across 36 of the 47 Member States. The most commonly reported disease outbreak was cholera which accounted for 20.8% (n = 20) of all events, followed by measles (n = 11, 11.5%) and Yellow fever (n = 7, 7.3%). About a quarter of the outbreaks (n = 23) were reported following signals detected through media monitoring conducted at the WHO regional office for Africa. The median delay between the disease onset and WHO notification was 16 days (range: 0–184). A total of 107 167 people were directly affected including 1221 deaths (mean case fatality ratio (CFR): 1.14% (95% confidence interval (CI) 1.07%–1.20%)). The highest CFR was observed for diseases targeted for eradication or elimination: 3.45% (95% CI 0.89%–10.45%). The African region remains prone to outbreaks of infectious diseases. It is therefore critical that Member States improve their capacities to rapidly detect, report and respond to public health events.

Writing Medical Records

1986 ◽  
Vol 16 (4) ◽  
pp. 331-341
Author(s):  
Michael P. Pagano ◽  
David Mair
Keyword(s):  
Medical Students ◽  
Medical Records ◽  
Medical Writing ◽  
Law School ◽  
Patient Records ◽  
Radiology Reports ◽  
Legal Implications ◽  
Composing Process ◽  
Medical Documents ◽  
School Faculty

A study was undertaken both to evaluate how medical students are taught to write patient records and to examine the writing done by doctors. Typical medical records, written by medical doctors, were also evaluated. A single questionnaire was sent to eighty-four medical school professors, twenty law school faculty, and five practicing attorneys. The questionnaire asked how medical records were used and what the legal implications were in authoring a patient record. The medical professionals were also asked how their schools taught medical writing. The questionnaire pointed out that most medical schools teach less than ten hours of medical writing in their curricula and that patient records are not written with an understanding of the various audiences, purposes, and uses for medical documents. Two radiology reports are discussed in terms of their clarity and usefulness for medical and extra-medical readers. The study concludes that medical students should be taught a composing process so that they will understand the audience, purpose, and use for the patient records they write.

Abstract 121: Vitamin D Deficiency Study in Postural Orthostatic Tachycardia Syndrome

2015 ◽  
Vol 8 (suppl_2) ◽  
Author(s):  
Chandralekha Ashangari ◽  
Amer Suleman
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Electronic Medical Records ◽  
Vitamin D3 ◽  
Medical Records ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Vitamin D Levels ◽  
The World ◽  
25 Oh Vitamin D ◽  
Vitamin D3 Deficiency

Objectives The aim of this study is to assess vitamin D levels, including the prevalence of vitamin D deficiency/insufficiency in Postural Orthostatic Tachycardia Syndrome (POTS) patients. Background : The Postural Orthostatic Tachycardia Syndrome (POTS) affects primarily young women. POTS is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. We frequently find vitamin D deficiency in patients who present with POTS Methods: 180 patients were selected randomly from our clinic with POTS. Patients Vitamin D levels charts were reviewed from electronic medical records, 25-OH vitamin D (Vitamin D3 ) status was defined as Normal (>30 ng/mL), Insufficient (20.0-29.9 ng/mL), and deficient (<20 ng/mL). Results: Out of 180 patients, 170 patients are female (94%, n=170, age 31.88±10.36), 10 patients are male (6% ,age 25.83±6.19). 79 patients had vitamin D3 level >30 ng/ml, 10 patients had vitamin D3 level range >20.0 to 29.9 ng/mL, 91 patients had vitamin D3 level < 20ng/mL. Conclusion: Our research results demonstrated that Postural Orthostatic Tachycardia Syndrome (POTS) patients have a higher rate of vitamin D3 deficiency (51% have Vitamin D3 less than 20 ng/mL). Vitamin D3 levels are low in more than half of POTS patients (56% had less than 30 ng/mL )

scholarly journals Could Personalised Self-Inking Stamps Improve Identification Standards in Medical Records?

2012 ◽  
Vol 94 (4) ◽  
pp. 128-130
Author(s):  
Sac MacKeith ◽  
Svelusamy ◽  
A Pajaniappane ◽  
P Jervis
Keyword(s):  
Medical Practice ◽  
Medical Records ◽  
General Medical Council ◽  
Case Note ◽  
Medical Council ◽  
Patient Records ◽  
Medical Case ◽  
Good Medical Practice ◽  
Professional Contact

Doctors' handwriting has long been criticised as being difficult to read or even illegible. In more recent years research has confirmed that it is not uncommon to find medical case note entries that are deficient, illegible or unidentifiable. In Good Medical Practice the General Medical Council (GMC) asks that doctors 'keep clear, accurate, legible and contemporaneous patient records'. In addition, the GMC 'expects that all doctors will use their reference numbers widely to identify themselves to all those with whom they have professional contact'. This includes encouragement for its use in case note entries and prescribing.

scholarly journals Gravity of injury and analgesia in patients who suffered traffic accidents

2008 ◽  
Vol 21 (3) ◽  
pp. 398-403 ◽  
Author(s):  
Ana Maria Calil ◽  
Cibele Andrucioli de Mattos Pimenta
Keyword(s):  
Retrospective Study ◽  
Outer Surface ◽  
Medical Records ◽  
Traffic Accidents ◽  
Emergency Services ◽  
World Health ◽  
Analgesic Drugs ◽  
Body Regions ◽  
The World ◽  
Reference Hospital

OBJECTIVE: Identifying the frequency and gravity of injuries in patients who suffered accidents in traffic and the analgesic drugs utilized. METHODS: Retrospective study, with a sample of 200 medical records of patients admitted to the emergency services of a reference hospital for trauma care. The gravity of the injuries was characterized by anatomic gravity rates and the analgesic therapy was based on the World Health Organization's Analgesic Ladder. RESULTS: The main findings pointed to injuries in limbs, head, face and outer surface as the most frequent, and, in 85% of the cases, gravity was equal or lower than 3; As for analgesia, it was verified that 46;6% of the patients received dipyrone and paracetamol. Among the opioids, meperidine was used in 10.4% of the cases. CONCLUSION: The gravity of most injuries was equal or lower to 3, indicating injuries of light, moderate and serious gravity, located especially in four body regions; regarding analgesia, dipyrone was shown to be the most commonly-used drug and a low use of opioids was verified.

scholarly journals Predictors of Burden of Care Among Caregivers of Drug-Naive Children and Adolescents With ADHD: A Cross-Sectional Correlative Study From Muscat, Oman

2018 ◽  
Vol 23 (5) ◽  
pp. 517-526 ◽  
Author(s):  
Naser Al-Balushi ◽  
Mohammed Al-Alawi ◽  
Muna Al Shekaili ◽  
Manal Al-Balushi ◽  
Hassan Mirza ◽  
...  
Keyword(s):  
Medical Records ◽  
Arabic Version ◽  
Burden Of Care ◽  
Cross Sectional ◽  
Children With Adhd ◽  
Adhd Diagnosis ◽  
Adhd Children ◽  
The World ◽  
Drug Naïve ◽  
Socio Demographic Factors

Objective: the study assessed the prevalence of burden of care among caregivers of children with ADHD in Oman. A related aim is to explore the predictors of the burden of care, subtypes of ADHD, and socio-demographic factors. Method: Arabic version of the Zarit Burden Interview (ZBI) was administered to 117 caregivers of drug-naive children with ADHD. Sociodemographic background and clinical data were gathered from medical records and from the attending caregivers themselves. The ADHD symptoms were grouped under three categories : hyperactive, inattentive, or mixed. Results: the prevalence of the burden of care was estimated to be 34%. Income levels and the child’s ADHD diagnosis being of “mixed” type have significant impact on the burden of care. Conclusion: the results of this study indicate that the prevalence of the burden of care among the caregivers of ADHD children in Oman is comparable with that in the other regions of the world.

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