scholarly journals Comparison of Heart Rate Variability Parameters in Patients with Cardiovascular Diseases and Concomitant Phenomenon of Heart Rate Turbulence wih the Indicators of Apparently Healthy Individuals

2018 ◽  
Vol 25 (1) ◽  
Author(s):  
A I Vytryhovskiy
Keyword(s):  
Heart Rate ◽  
Coronary Heart Disease ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Healthy Individuals ◽  
High Cardiovascular Risk ◽  
Heart Rate Turbulence ◽  
Very High ◽  
Apparently Healthy

The objective of the research was to develop new approaches to the prognosis, prevention and treatment of complications in patients at high and very high total cardiovascular risk based on the assessment of the state and effect on heart rate variability and heart rate turbulence.Materials and methods. There were examined 319 patients; they underwent a 24-hour monitoring of their heart rate variability and heart rate turbulence. All the patients were divided into three groups: Group 1 included patients with coronary heart disease (post-infarction cardiosclerosis) without concomitant risk factors such as smoking, obesity, metabolic syndrome; Group 2 consisted of patients smoking tobacco for more than 2 years; Group 3 included patients with metabolic syndrome and arterial hypertension; the control group.Results. In patients with coronary heart disease and concomitant phenomenon of heart rate turbulence, the activity of the parasympathetic nervous system was significantly higher in the active period of the day, while the passive period of the day was associated with the elevated level of stress. Due to this, among patients of this group, there was a decrease in the tension value of the total body regulation in the passive period of the day, while in healthy individuals, its increase was observed. In patients at high and very high cardiovascular risk according to the SCORE charts with the phenomenon of heart rate turbulence, the stress index was significantly higher throughout the day as compared to apparently healthy individuals. In patients at high cardiovascular risk and concomitant phenomenon of heart rate turbulence, the parameters of heart rate turbulence acceleration were significantly higher as compared to those of apparently healthy individuals.Conclusions. In patients at high and very high cardiovascular risk according to the SCORE charts with coronary heart disease and concomitant phenomenon of heart rate turbulence, the occurrence of ventricular extrasystole had a vagal nature; they were characterized by a higher level of stress in the passive period of the day as compared to the active one.

scholarly journals Features of Heart Rate Variability in Patients with Coronary Heart Disease and Risk Factors for Cardiovascular Disease According to the SCORE Charts in the Presence of Heart Rate Turbulence

2016 ◽  
Vol 23 (3) ◽  
Author(s):  
A. I. Vytryhovskyy
Keyword(s):  
Metabolic Syndrome ◽  
Heart Rate ◽  
Coronary Heart Disease ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
High Cardiovascular Risk ◽  
Heart Rate Turbulence ◽  
Normal Limits ◽  
Very High

The objective of the research was to develop new approaches to the prediction, prevention and treatment of complications in patients at high and very high total cardiovascular risk based on the assessment of heart rate turbulence.Materials and methods. 319 patients were examined to study the role of heart rate turbulence in the formation and progression of sudden cardiac death in the cardiovascular continuum based on the Holter monitoring. All patients were divided into 4 groups: Group 1 included patients with coronary heart disease without concomitant risk factors such as smoking, obesity, metabolic syndrome; Group 2 consisted of patients smoking tobacco for more than 2 years (those at very high cardiovascular risk); Group 3 included patients with metabolic syndrome without existing coronary heart disease or arterial hypertension (those at high cardiovascular risk); Group 4 consisted of 50 patients with metabolic syndrome and arterial hypertension (the control group).Results. In practically healthy people with the phenomenon of heart rate turbulence, there was a high level of sympathetic activity of the autonomic nervous system, which was more pronounced in the passive period of the day. In people with postinfarction cardiosclerosis and the phenomenon of heart rate turbulence hypersympathicotonia being associated with high psycho-emotional stress was typical in the active as well as the passive period of the day; the central mechanisms of regulation prevailed over autonomous ones. In people with coronary heart disease (postinfarction cardiosclerosis) psycho-emotional stress and functional state of the cerebral cortex played an important role in the pathogenesis of the disease. In the passive period of the day, the tension value of the total body regulation decreased, mainly due to high-frequency component of heart rate variability. Hypersympathicotonia and high activity of the vasomotor center at night explain the high incidence of complications and exacerbations of coronary artery disease in the passive period of the day.  In individuals at very high cardiovascular risk according to the SCORE charts with the phenomenon of heart rate turbulence the QT interval lengthening was not observed. The feature of this group was the moderate total tension of heart rate variability in the active period of the day and its rise to the highest limits during the passive period of the day, which was associated with low activity of all spectra. The stress index in patients at very high cardiovascular risk according to the SCORE charts in the passive period of the day reduced compared to the active period of the day. The indices of acceleration and deceleration of the sinus rhythm in patients at very high cardiovascular risk according to the SCORE charts were within normal limits. In individuals at high cardiovascular risk according to the SCORE charts with the phenomenon of heart rhythm turbulence the parameters of heart rate turbulence acceleration were below normal limits; the paramters of deceleration were normal; shortening of the QT interval was not observed.Conclusions. The determination of heart rate turbulence is quite simple, non-invasive, affordable screening method of forecasting the occurrence and development of cardiovascular diseases as well as early detection of patients predisposed to sudden cardiac death in the general population.

scholarly journals Time Domain Measures Of Heart Rate Variability In Heavy Workers

1970 ◽  
Vol 6 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Sangita Mithun ◽  
Noorzahan Begum ◽  
Sultana Ferdousi ◽  
Shelina Begum ◽  
Taskina Ali
Keyword(s):  
Physical Activity ◽  
Heart Rate ◽  
Coronary Heart Disease ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Time Domain ◽  
Autonomic Nerve ◽  
Cross Sectional ◽  
Socioeconomic Condition ◽  
Apparently Healthy

Background: Physical inactivity and low resting heart rate variability (HRV) are associated with increased incidence of coronary heart disease. Heavy physical activity is associated with higher heart rate variability and reduces the risk of coronary heart disease Objective: To assess some time domain measures of HRV in order to compare Cardiac Autonomic Function between sedentary and heavy workers. Methods: This cross sectional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University between 1st July 2008 to 30th June 2009 on 30 apparently healthy heavy workers aged 28-50 years from low socioeconomic condition (study group). For comparison 30 age, sex, BMI and socioeconomic status matched apparently healthy sedentary subjects (group A) were also studied. The study subjects were selected among rickshaw-pullers living in the slum areas nearby BSMMU, Dhaka and the controls were from fourth class employee of BSMMU, Dhaka. Heart Rate Variability were assessed by a Polygraph. Several time domain measures of HRV such as mean R-R interval, mean HR, SDNN, RMSSD were analyzed. For statistical analysis, Independent-Samples t-test, and Pearson’s correlation coefficient tests were done as applicable. Results: Resting mean heart rate (P<0.01), SDNN (P<0.01) and RMSSD (P<0.001) were significantly lower but mean R-R interval (P<0.001) was significantly higher in heavy workers than those of sedentary control. The mean R-R interval (P<0.05) showed significant positive correlation in heavy workers but significant negative correlation in sedentary workers with BMI. Conclusion: Cardiac autonomic nerve function status may be higher with parasympathetic dominance by increased physical activity. DOI: http://dx.doi.org/10.3329/jbsp.v6i2.9755 JBSP 2011 6(2): 77-83

Antidepressants, autonomic function and mortality in patients with coronary heart disease: data from the Heart and Soul Study

2014 ◽  
Vol 44 (14) ◽  
pp. 2975-2984 ◽  
Author(s):  
F. Zimmermann-Viehoff ◽  
L. K. Kuehl ◽  
H. Danker-Hopfe ◽  
M. A. Whooley ◽  
C. Otte
Keyword(s):  
Heart Rate ◽  
Coronary Heart Disease ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Tricyclic Antidepressants ◽  
Autonomic Function ◽  
Control Group ◽  
Observational Period ◽  
Lower Heart Rate

BackgroundAntidepressants reduce depressive symptoms in patients with coronary heart disease, but they may be associated with increased mortality. This study aimed to examine whether the use of tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRI) is associated with mortality in patients with coronary heart disease, and to determine whether this association is mediated by autonomic function.MethodA total of 956 patients with coronary heart disease were followed for a mean duration of 7.2 years. Autonomic function was assessed as heart rate variability, and plasma and 24-h urinary norepinephrine.ResultsOf 956 patients, 44 (4.6%) used TCA, 89 (9.3%) used SSRI, and 823 (86.1%) did not use antidepressants. At baseline, TCA users exhibited lower heart rate variability and higher norepinephrine levels compared with SSRI users and antidepressant non-users. At the end of the observational period, 52.3% of the TCA users had died compared with 38.2% in the SSRI group and 37.3% in the control group. The adjusted hazard ratio (HR) for TCA use compared with non-use was 1.74 [95% confidence interval (CI) 1.12–2.69, p = 0.01]. Further adjustment for measures of autonomic function reduced the association between TCA use and mortality (HR = 1.27, 95% CI 0.67–2.43, p = 0.47). SSRI use was not associated with mortality (HR = 1.15, 95% CI 0.81–1.64, p = 0.44).ConclusionsThe use of TCA was associated with increased mortality. This association was at least partially mediated by differences in autonomic function. Our findings suggest that TCA should be avoided in patients with coronary heart disease.

Non-linear analysis of heart rate variability in patients with coronary heart disease

2003 ◽  
Author(s):  
G. Krstacic ◽  
A. Krstacic ◽  
M. Martinis ◽  
E. Vargovic ◽  
A. Knezevic ◽  
...  
Keyword(s):  
Heart Rate ◽  
Coronary Heart Disease ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Linear Analysis ◽  
Non Linear
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