Suitable Experimental Design for Determination of Auxin Polar Transport in Space Using a Spacecraft.

This review paper deals with the use of statistical methods to evaluate systematic and random errors associated with trigonometric parallaxes. First, systematic errors which arise when using trigonometric parallaxes to calibrate luminosity systems are discussed. Next, determination of the external errors of parallax measurement are reviewed. Observatory corrections are discussed. Schilt’s point, that as the causes of these systematic differences between observatories are not known the computed corrections can not be applied appropriately, is emphasized. However, modern parallax work is sufficiently accurate that it is necessary to determine observatory corrections if full use is to be made of the potential precision of the data. To this end, it is suggested that a prior experimental design is required. Past experience has shown that accidental overlap of observing programs will not suffice to determine observatory corrections which are meaningful.

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Respirometry for determination of the influents SS-concentration

Water Science & Technology ◽

10.2166/wst.1996.0031 ◽

1996 ◽

Vol 33 (1) ◽

pp. 311-323 ◽

Cited By ~ 2

Author(s):

A. Witteborg ◽

A. van der Last ◽

R. Hamming ◽

I. Hemmers

Keyword(s):

Experimental Design ◽

Activated Sludge ◽

Substrate Concentration ◽

Full Scale ◽

Activated Sludge Process ◽

Respiration Rates ◽

On Line ◽

Large Measurement ◽

Set Up

A method is presented for determining influent readily biodegradable substrate concentration (SS). The method is based on three different respiration rates, which can be measured with a continuous respiration meter which is operated in a cyclic way. Within the respiration meter nitrification is inhibited through the addition of ATU. Simulations were used to develop the respirometry set-up and decide upon the experimental design. The method was tested as part of a large measurement programme executed at a full-scale plant. The proposed respirometry set-up has been shown to be suitable for a semi-on-line determination of an influent SS which is fully based on the IAWQ #1 vision of the activated sludge process. The YH and the KS play a major role in the principle, and should be measured directly from the process.

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Optimization of Solid-phase Extraction by Experimental Design Methodology for Determination of Lead Ions Using Graphene Modified Nano-sheets as a Novel Sorbent

Current Analytical Chemistry ◽

10.2174/157341101004140701114909 ◽

2014 ◽

Vol 10 (4) ◽

pp. 512-521 ◽

Cited By ~ 6

Author(s):

Omid Sayar ◽

Forouzan Aboufazeli ◽

Hamid Zhad ◽

Omid Sadeghi ◽

Mohammad Karimi ◽

...

Keyword(s):

Experimental Design ◽

Solid Phase Extraction ◽

Design Methodology ◽

Solid Phase ◽

Lead Ions ◽

Phase Extraction ◽

Experimental Design Methodology

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Optimum HPLC Conditions for Determination of Dibucaine HCL, Fluocortolone Pivalate and Fluocortolone Caproate by Using Experimental Design

Current Pharmaceutical Analysis ◽

10.2174/1573412913666170707113025 ◽

2018 ◽

Vol 15 (1) ◽

pp. 32-38 ◽

Cited By ~ 1

Author(s):

Bürge Aşçı ◽

Mesut Koç

Keyword(s):

Experimental Design ◽

Flow Rate ◽

Mobile Phase ◽

High Performance ◽

Limit Of Detection ◽

Pharmaceutical Preparations ◽

Acid Mixture ◽

Solution Stability ◽

Uv Detector

Introduction:This paper presents the development and validation of a novel, fast, sensitive and accurate high performance liquid chromatography (HPLC) method for the simultaneous quantitative determination of dibucaine HCl, fluocortolone pivalate and fluocortolone caproate in pharmaceutical preparations.Experiment:Development of the chromatographic method was based on an experimental design approach. A five-level-three-factor central composite design requiring 20 experiments in this optimization study was performed in order to evaluate the effects of three independent variances including mobile phase ratio, flow rate and amount of acid in the mobile phase.Conclusion:The optimum composition for mobile phase was found as a methanol:water:acetic acid mixture at 71.6 : 26.4 : 2 (v/v/v) ratio and optimum separation was acquired by isocratic elution with a flow rate of 1.3 mL/min. The analytes were detected using a UV detector at 240 nm. The developed method was validated in terms of linearity, precision, accuracy, limit of detection/quantitation and solution stability and successfully applied to the determination of dibucaine HCl, fluocortolone pivalate and fluocortolone caproate in pharmaceutical topical formulations such as suppositories and ointments.

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