Intellectual mapping of studies on obsessive-compulsive disorder (OCD): A machine learning study (Preprint)

2021 ◽  
Author(s):  
Behnaz Bakhshinejad ◽  
Mahdiyeh Khazaneha ◽  
Mitra Mehrabani ◽  
Ali sadatmoosavi ◽  
Oranus Tajedini ◽  
...  

BACKGROUND Background: This study examines the relationship between obsessive-compulsive disorder (OCD) and other medical conditions and their role in the development or treatment of this disorder OBJECTIVE A co-word analysis study examines the status and intellectual structure of obsessive-compulsive disorder. Furthermore, given the multiplicity of outputs obtained from this type of study, the results can be connected to various fields related to the disease, and other related diseases can be identified through visualization. Drawing the intellectual structure in emerging and declining fields, the level of development and maturity, thematic networks and determining the thematic relationship of OCD with other diseases, the role of genetic factors, the role of complementary medicine in the treatment of this disease, etc. are among some contributions of this research project METHODS Materials and Methods: The articles published from 1975 to 2021 were retrieved by searching the related keywords in multiple databases including PubMed, Scopus, Web of Science (WoS), and Embase according to their thematic coverage and scope. Finally, after removing repeated articles and standardization, a total of 1820 papers were analyzed using R and SciMAT software. RESULTS A total of 4191 keywords plus (ID) and 3242 author keywords (DE) were reported in the journals. Moreover, these articles were published by 7482 authors, of which 111 articles were written by single authors and the collaborative coefficient (CC) was 4.36. Neuropsychopharmacology International Clinical, Psychopharmacology, and Journal of Clinical Psychopharmacology are the most influential journals publishing OCD articles. CONCLUSIONS Given the increasing prevalence of obsessive-compulsive disorders (OCDs), finding the most effective methods with the lowest prescribed dose of the drug and the most therapeutic effect is extremely important. To this end, the present study indicated that the prognosis of inherited OCD disorders, as well as the response to treatment, can be examined by analyzing the genetic sequence and finding polymorphism cases. Furthermore, complementary medicine as one of the scientific schools plays an important role in OCD diagnosis and adjuvant treatment using food and herbs and other treatment methods.

1999 ◽  
Vol 54 (6) ◽  
pp. 213-221 ◽  
Author(s):  
Alex S. S. Freire Maia ◽  
Egberto Reis Barbosa ◽  
Paulo Rossi Menezes ◽  
Eurípedes C. Miguel Filho

Obsessive-compulsive disorder (OCD) has been reported in association with some neurological diseases that affect the basal ganglia such as Tourette's syndrome, Sydenham's chorea, Parkinson's disease, and Huntington's disease. Furthermore, studies such as neuroimaging, suggest a role of the basal ganglia in the pathophysiology of OCD. The aim of this paper is to describe the association of OCD and several neurologic disorders affecting the basal ganglia, report the existing evidences of the role of the basal ganglia in the pathophysiology of OCD, and analyze the mechanisms probably involved in this pathophysiology.


2017 ◽  
Vol 7 (2) ◽  
pp. 7-25
Author(s):  
Karolina Diallo

Pupil with Obsessive-Compulsive Disorder. Over the past twenty years childhood OCD has received more attention than any other anxiety disorder that occurs in the childhood. The increasing interest and research in this area have led to increasing number of diagnoses of OCD in children and adolescents, which affects both specialists and teachers. Depending on the severity of symptoms OCD has a detrimental effect upon child's school performance, which can lead almost to the impossibility to concentrate on school and associated duties. This article is devoted to the obsessive-compulsive disorder and its specifics in children, focusing on the impact of this disorder on behaviour, experience and performance of the child in the school environment. It mentions how important is the role of the teacher in whose class the pupil with this diagnosis is and it points out that it is necessary to increase teachers' competence to identify children with OCD symptoms, to take the disease into the account, to adapt the course of teaching and to introduce such measures that could help children reduce the anxiety and maintain (or increase) the school performance within and in accordance with the school regulations and curriculum.


CNS Spectrums ◽  
2000 ◽  
Vol 5 (S4) ◽  
pp. 4-4
Author(s):  
Eric Hollander ◽  
Joseph Zohar ◽  
Donatella Marazziti

The Fourth International Obsessive Compulsive Disorder Conference (IOCDC) was held February 10–12, 2000, on the beautiful island of St. Thomas. The IOCDC is an annual meeting which brings together the world's leading experts in obsessive-compulsive disorder (OCD) and related disorders in a small workshop setting to present recent research advances, discuss gaps in our current knowledge, and plan or international approaches that address these knowledge gaps. The IOCDC meetings have been held on islands on both sides of the Atlantic—Capri, Guadeloupe, Madeira, and now St. Thomas.The International Organizing Committee consists of Eric Hollander, MD (USA), Joseph Zohar, MD (Israel), and Donatella Marazziti, MD (Italy). The proceedings are generously supported by an unrestricted educational grant from Solvay Pharmaceuticals Inc. and Solvay Pharmaceuticals, and we would like to acknowledge the very important contributions of Chantal Vekens and Mary Blangiardo of Solvay. Also, an mportant part of the success of these meetings stems from the very active role of the chairpersons and cochairpersons of the workshops who lead the discussions, who synthesize the future directions and prepare the manuscripts that result from these discussions that appear in this academic supplement.The meeting led off with a state-of-the-art plenary address by Mark George, MD (USA), describing how new methods of brain stimulation are improving research and therapy in OCD and promise to revolutionize neuropsychiatric research and herapy over the next decade. He describes how transcranial magnetic stimulation (TMS) is used to test the circuits in OCD and test electrophysiologic evaluations of cortical inhibition n OCD. Newer techniques that are less invasive than ablative surgery and appear promising in OCD therapy include vagus nerve stimulation and deep brain stimulation.


2014 ◽  
Vol 121 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Andre F. Gentil ◽  
Antonio C. Lopes ◽  
Darin D. Dougherty ◽  
Christian Rück ◽  
David Mataix-Cols ◽  
...  

Object Recent findings have suggested a correlation between obsessive-compulsive disorder (OCD) symptom dimensions and clinical outcome after limbic system surgery for treatment-refractory patients. Based on previous evidence that the hoarding dimension is associated with worse outcome in conventional treatments, and may have a neural substrate distinct from OCD, the authors examined a large sample of patients undergoing limbic surgery (40 with capsulotomy, 37 with cingulotomy) and investigated if symptom dimensions, in particular hoarding, could influence treatment outcome. Methods Data from 77 patients from 3 different research centers at São Paulo (n = 17), Boston (n = 37), and Stockholm (n = 23) were analyzed. Dimensional Yale-Brown Obsessive Compulsive Scale (Y-BOCS; São Paulo) or Y-BOCS Symptom Checklist scores (Boston and Stockholm) were used to code the presence of 4 well-established symptom dimensions: forbidden thoughts, contamination/cleaning, symmetry/order, and hoarding. Reductions in YBOCS scores determined clinical outcome. Results Mean Y-BOCS scores decreased 34.2% after surgery (95% CI 27.2%–41.3%), with a mean follow-up of 68.1 months. Patients with hoarding symptoms had a worse response to treatment (mean Y-BOCS decrease of 22.7% ± 25.9% vs 41.6% ± 32.2%, respectively; p = 0.006), with no significant effect of surgical modality (capsulotomy vs cingulotomy). Patients with forbidden thoughts apparently also had a worse response to treatment, but this effect was dependent upon the co-occurrence of the hoarding dimension. Only the negative influence of the hoarding dimension remained when an ANOVA model was performed, which also controlled for preoperative symptom severity. Conclusions The presence of hoarding symptoms prior to surgery was associated with worse clinical outcome after the interventions. Patients with OCD under consideration for ablative surgery should be carefully screened for hoarding symptoms or comorbid hoarding disorder. For these patients, the potentially reduced benefits of surgery need to be carefully considered against potential risks.


Author(s):  
Esmaeil Sadri Damirchi ◽  
Arezoo Mojarrad ◽  
Saeed Pireinaladin ◽  
Andrej M M Grjibovski

Objective: Nowadays, the outbreak of Coronavirus (COVID-19) is one of the most stressful resources that has led to the rise of different levels of psychological crisis. In addition to the countries affected by the COVID-19, such as China, European and American countries, Iran has appeared as one of the most affected countries with high infected cases and deaths. Thus, the purpose of this study was to investigate the role of self-talk in predicting death anxiety, obsessive-compulsive disorder, and coping strategies in the face of COVID-19. Method: This descriptive and correlational study was conducted on 354 adults living in Ardabil, Iran, who were selected using cluster sampling from 21 January to 19 March 2020. Self-Talk questionnaires, Coping Strategies, Death Anxiety, and Obsessive-Compulsive questionnaires were used for data collection. Descriptive statistics, Pearson correlation, and multiple linear regression were used for data analysis. Results: The findings revealed a significant positive relationship between self-talk and problem-centered coping style. Also, significant negative relationships were found between self-talk and emotional coping style, death anxiety, and obsessive-compulsive disorder. Furthermore, based on the results of the regression test, self-talk predicted problem-centered style, emotional-coping style, death anxiety, and obsessive-compulsive disorder. Conclusion: The results of this study emphasize the need for psychological crisis intervention during the COVID-19 outbreak. Also, this study provides an important step in shifting attention to self-talk skills from sport psychology fields toward clinical psychology, especially about the mental impacts of COVID-19.


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