Effectiveness and cost-effectiveness of brief Mindfulness-Based Cognitive Therapy for the improvement of productivity in the workplace: Study protocol for a randomized controlled trial (Preprint)

2021 ◽  
Author(s):  
Mitsuhiro Sado ◽  
Masashi Yamada ◽  
Akira Ninomiya ◽  
Maki Nagaoka ◽  
Naho Goto ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Cognitive Therapy ◽  
Work Performance ◽  
Controlled Trial ◽  
Self Report ◽  
World Health ◽  
Control Group ◽  
Work Related ◽  
Health Organization ◽  
The Impact

BACKGROUND Numerous studies have demonstrated the effectiveness of Mindfulness Based Programs’ (MBPs) among both clinical and non-clinical populations. These data document positive impacts in the workplace, including reducing perceived stress and burnout and increasing wellbeing. However, the effectiveness for productivity, which is of most interest to managers and administrators, is still unclear. In addition, MBPs in the workplace tend to be modified by reducing the number of the program sessions or delivering content online to improve accessibility. To date, however, the impact on productivity of MBPs in the workplace that feature these modifications has not been investigated. OBJECTIVE The study aimed to investigate the effectiveness and cost-effectiveness of the online-delivered brief Mindfulness Based Cognitive Therapy (bMBCT) for improving productivity and other work related outcomes. METHODS We conduct a four-week RCT with a six-month follow-up. Employees are included in the study if they 1) are between the ages of 20-65 and 2) work longer than 30 hours weekly. Employees were randomly allocated to either the bMBCT group or wait-list control group. The primary outcome of the study is the mean difference of productivity measured by World Health Organization Health and Work Performance Questionnaire (WHO-HPQ) between the groups at 4, 16, 28 weeks. Secondary outcomes include several clinical outcomes and health economics evaluation. RESULTS Recruitment began in August 2021. 104 participants have been enrolled in the study as of October 2021. The intervention is ongoing and scheduled to be completed in December 2023. Data collection will be completed by March 2024. CONCLUSIONS The novelty of the study is that 1) it will investigate the bMBCTs’ effectiveness on productivity, which is still unclear, 2) samples are recruited from three companies in different industries, etc. The limitations of the study are 1) all measures assessed are self-report format, 2) we lack an active control group. This study has the potential to provide new data on the relationship between MBPs and occupational health and productivity. CLINICALTRIAL UMIN Clinical Trials Registry: UMIN000044721

scholarly journals Lower peripheral blood Toll-like receptor 3 expression is associated with an unfavorable outcome in severe COVID-19 patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maria Clara Saad Menezes ◽  
Alicia Dudy Müller Veiga ◽  
Thais Martins de Lima ◽  
Suely Kunimi Kubo Ariga ◽  
Hermes Vieira Barbeiro ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Peripheral Blood ◽  
World Health ◽  
Control Group ◽  
Pyrin Domain ◽  
Peripheral Blood Gene Expression ◽  
Severe Group ◽  
Health Organization ◽  
The Impact

AbstractThe role of innate immunity in COVID-19 is not completely understood. Therefore, this study explored the impact of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection on the expression of Pattern Recognition Receptors (PRRs) in peripheral blood cells and their correlated cytokines. Seventy-nine patients with severe COVID-19 on admission, according to World Health Organization (WHO) classification, were divided into two groups: patients who needed mechanical ventilation and/or deceased (SEVERE, n = 50) and patients who used supplementary oxygen but not mechanical ventilation and survived (MILD, n = 29); a control group (CONTROL, n = 17) was also enrolled. In the peripheral blood, gene expression (mRNA) of Toll-like receptors (TLRs) 3, 4, 7, 8, and 9, retinoic-acid inducible gene I (RIGI), NOD-like receptor family pyrin domain containing 3 (NLRP3), interferon alpha (IFN-α), interferon beta (IFN-β), interferon gamma (IFN-γ), interferon lambda (IFN-λ), pro-interleukin(IL)-1β (pro-IL-1β), and IL-18 was determined on admission, between 5–9 days, and between 10–15 days. Circulating cytokines in plasma were also measured. When compared to the COVID-19 MILD group, the COVID-19 SEVERE group had lower expression of TLR3 and overexpression of TLR4.

scholarly journals Impact of schistosomiasis on quality of life and productivity of workers

2002 ◽  
Vol 8 (2-3) ◽  
pp. 354-362
Author(s):  
M. I. Kamel
Keyword(s):  
Quality Of Life ◽  
World Health ◽  
Control Group ◽  
Hours Of Work ◽  
Productivity Indicators ◽  
Health Organization ◽  
General Physical ◽  
Textile Factory ◽  
The Impact

The effect of schistosomiasis on quality of life [QOL] and productivity of workers was examined. In a textile factory in Alexandria, Egypt, personal, occupational and sociodemographic data were collected from 172 workers with schistosomiasis and 172 workers without schistosomiasis. Several indicators of productivity and the World Health Organization QOL brief were used to determine the impact of schistosomiasis. The disease affected the general, physical and independence, psychological and spiritual, and social domains of QOL. Although the productivity score of workers with schistosomiasis did not differ significantly from the control group, they had significantly lower additional hours of work and lower total incentives/month. A significant relationship was found between severity of schistosomiasis and QOL domains and productivity indicators.

scholarly journals Online supervised versus workplace corrective exercises for upper crossed syndrome: a protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Zohreh Yaghoubitajani ◽  
Mehdi Gheitasi ◽  
Mohammad Bayattork ◽  
Lars Louis Andersen
Keyword(s):  
Social Insurance ◽  
Work Performance ◽  
Controlled Trial ◽  
Productivity Loss ◽  
Office Workers ◽  
Control Group ◽  
Serratus Anterior ◽  
Exercise Interventions ◽  
Work Related ◽  
Supervised Exercise

Abstract Background and objective Musculoskeletal disorders (MSDs) including upper crossed syndrome (UCS) are considered as the leading cause of work-related issues worldwide among office workers. Therefore, the present study aims to evaluate the effect of workplace-based versus online-supervised home-based corrective exercises among office workers with UCS. Methods and design To this end, 45 subjects within the age range of 30–45 years are randomly assigned to three groups in the present parallel-group, randomized control trial using a pretest-posttest design. These groups include the subjects who receive online-supervised exercise and workplace exercise containing three sessions of intervention for 8 weeks and the control group receives no intervention while performing routine activities. The primary outcome variables are neck-shoulder pain (NSP) and consequent sick leave due to NSP, followed by alignment, workability, and the surface electromyography of upper, middle, and lower trapezius (UT, MT, and LT), sternocleidomastoid (SCM), and serratus anterior (SA) as the secondary variables. Discussion The present study seeks to assess the effect of workplace versus online-supervised corrective exercise interventions among 45 office workers suffering from UCS. It is expected to improve and reduce the related symptoms including postural malalignment and imbalance muscles after 8 weeks of corrective exercises. If effective, the findings may lead to adherence and work performance among the office workers, and individuals subjected to UCS can use the benefits of an online-supervised intervention. In addition, the findings may be useful in different workplaces as the evidence for employers to benefit from the reduction in the related costs and side effects of work-related neck/shoulder disorders including work disability, productivity loss, time expense, social insurance, work absenteeism, and treatment costs. Finally, clinicians and corrective exercise therapists can consider it as a clinical based-evidence intervention for their further actions. Trial registration Iranian Registry of Clinical Trials IRCT20200729048249N1. Registered on 5 October 2020 (https://en.irct.ir/user/trial/49992/view)

scholarly journals Tianwang Buxin Granules Influence the Intestinal Flora in Perimenopausal Insomnia

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Xiqian Yang ◽  
Hesong Xiao ◽  
Yi Zeng ◽  
Liangliang Huang ◽  
Ke Ji ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Controlled Trial ◽  
Intestinal Flora ◽  
World Health ◽  
Control Group ◽  
Metagenomic Sequencing ◽  
Clinical Trial Registry ◽  
Clinical Trial Registration ◽  
Faecalibacterium Prausnitzii ◽  
Health Organization

Study Objectives. To study the relationship between perimenopausal insomnia (PI) and intestinal flora and the potential mechanism of Tianwang Buxin granules (TWBXG) in exerting its clinical efficacy. Methods. The subjects included 13 PI patients from the Hubei Provincial Hospital of TCM, Hubei University of TCM, and Wuhan Traditional Chinese Medicine Hospital, and the corresponding noninsomniac spouses of the patients were selected as controls. TWBXG was continuously administered for 4 weeks. The feces of PI patients and their noninsomniac spouses before and after treatment with TWBXG were collected. The intestinal flora composition of each group was detected by metagenomic sequencing, and the efficacy of TWBXG was evaluated by the PSQI scale. Results. Compared with the control group, the model group showed an increase in the abundance of Roseburia faecis, Ruminococcus, Prevotella copri, Fusicatenibacter saccharivorans, and Blautia obeum, while those of Bacteroides, fecal Bacteroidetes, and Faecalibacterium prausnitzii were decreased. Compared with pretreatment, the PSQI score was significantly reduced ( P < 0.05 ), the abundance of Bacteroides, fecal Bacteroidetes, and Faecalibacterium prausnitzii increased, and that of Roseburia faecis, Ruminococcus, Prevotella copri, Fusicatenibacter saccharivorans, and Blautia obeum decreased after treatment. However, there was still a certain gap in the abundance of related flora in the treatment group compared with the control. Conclusion. PI is associated with disturbances in the intestinal flora and is mainly related to the disorders of Roseburia faecis, Ruminococcus, Prevotella copri, Fusicatenibacter saccharivorans, Blautia obeum, Bacteroides, fecal Bacteroidetes, and Faecalibacterium prausnitzii. TWBXG can effectively treat PI, and its effect may be achieved by regulating the disordered intestinal flora. Clinical Trials. The study was registered in the Chinese clinical trial registry and approved by the World Health Organization clinical trial registration platform (Effects of the modified Tianwang Buxin granule and modified Tianwang Buxin decoction pieces on insomnia: a randomized, controlled trial, ChiCTR-IPR-17011549).

Dose-Response Study of Formaldehyde on Nasal Mucosa Swelling. A Study on Residents with Nasal Distress at Home

1994 ◽  
Vol 8 (3) ◽  
pp. 143-146 ◽  
Author(s):  
Jan E. Falk ◽  
Jan E. Juto ◽  
Göran Stridh ◽  
Gunnar Bylin
Keyword(s):  
Nasal Mucosa ◽  
World Health ◽  
Control Group ◽  
Great Effort ◽  
Indoor Climate ◽  
Sick Building ◽  
Health Organization ◽  
The Individual ◽  
Dose Response Study ◽  
The Impact

Despite great effort, it has been difficult to demonstrate in an objective way any impact of sick building environment on affected individuals. The aim of this study was to learn whether or not it is possible with rhinostereometry to register changes in the nasal mucosa swelling at exposure to formaldehyde in concentrations 0–0.174 mg/m3. Seven persons, non-allergic, otherwise healthy, and with a history of nasal distress in their homes, participated in the study. Six healthy persons, without nose problems, were controls. Each person was exposed to formaldehyde in different concentrations during two hours in a climate chamber. Increased swelling was recorded al the two highest concentrations (0.073 and 0.174 mg/m3) in the symptomatic group. The control group did not show any mucosal swelling. It was possible to demonstrate an increased mucosal swelling that must be attributed to exposure to formaldehyde. This was possible at formaldehyde concentrations close to the (0.125 mg/m3) upper limit for indoor climate recommended by the World Health Organization (WHO). The study model can be considered useful for further investigations of the impact on the individual from other airborne irritants connected to sick building environments.

A Controlled Trial of a Quit and Win Contest

2005 ◽  
Vol 20 (2) ◽  
pp. 117-126 ◽  
Author(s):  
Ellen J. Hahn ◽  
Mary Kay Rayens ◽  
Todd A. Warnick ◽  
Costel Chirila ◽  
Robert T. Rasnake ◽  
...  
Keyword(s):  
Treatment Group ◽  
Tobacco Use ◽  
Low Income ◽  
Controlled Trial ◽  
Community Support ◽  
Self Report ◽  
Control Group ◽  
Media Campaign ◽  
Urine Cotinine ◽  
The Impact

Purpose. To evaluate the impact of a state-of-the-art Quit and Win contest on tobacco quit rates at 3, 6, and 12 months after the 30-day quit period. Design. Quasi-experimental with a volunteer sample of 494 Quit and Win contest registrants (treatment group) and 512 randomly selected tobacco users not exposed to the promotional media campaign (control group). Intervention included a 30-day quit period to be eligible for large cash prizes; provider advice via weekly mailings; online and telephone quit assistance; media campaign; and community support. Setting. Community-based intervention in Kentucky. Subjects. A total of 1006 adult tobacco users. Measures. Quit rates were measured using 7-day point prevalence for tobacco use. Urine cotinine measurements confirmed self-reported quitting. Results. Treatment group participants were significantly more likely than controls to experience quitting during the 1-year follow-up, as determined by both self-report and urine confirmation. After adjusting for baseline differences in demographics, tobacco use, and stage of change, those in the treatment group had 2.6 times the odds of reporting quitting in the postintervention period and 5.3 times the odds of experiencing quitting confirmed by urine cotinine, relative to controls. Women, minorities, and low-income tobacco users had equal odds of quitting as men, whites, and those with higher incomes. Conclusions. That the contest was minimally intensive and yielded a relatively high quit rate demonstrates the potential effectiveness of the intervention.

scholarly journals Impact of residents’ involvement in urological surgeries: a systematic review

2021 ◽  
Vol 8 (4) ◽  
pp. 2012
Author(s):  
Wedyan Salem Basaif ◽  
Faisal Abdulaziz Almukhlifi ◽  
Abdulhadi Turki Alsubaie ◽  
Ali Mohammed Alzarqa ◽  
Ahmed Abdulsalam Alsaedi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Operative Time ◽  
Controlled Trial ◽  
World Health ◽  
Cochrane Library ◽  
Primary Surgery ◽  
Urological Procedures ◽  
Health Organization ◽  
Randomised Controlled ◽  
The Impact

Many investigations have reported the impact of resident involvement in urological surgeries. We aimed to conduct this systematic review to create enough evidence regarding this impact based on the outcomes obtained from the relevant studies. We have performed both manual and electronic search through many databases like Google Scholar, Web of science, PubMed, Scopus, Cochrane library, the international standard randomised controlled trial number registry, and the world health organization virtual health library to obtain all the relevant citations. Our intended outcomes included the risk of developing complications, operative time, and rate of reoperations. We have included 17 studies that reported the impact of residents’ involvement in urological surgical operations. while some studies reported some complications, the risk of developing complications was not significantly associated with residents' involvement according to most studies. Only one study reported that complications were significantly associated with residents’ involvement. The rate of reoperation and readmission after the primary surgery was also non-significant. On the other hand, most of the included studies showed that residents’ involvement was significantly associated with increased hospital stay and prolonged operative time. Our results indicate the residents’ involvement does not impact the overall safety of the urological procedures and that this practice should be encouraged with adequate supervision. 

Psychoeducation Group on Improving Quality of Life of Mild Cognitive Impaired Elderly

2017 ◽  
Vol 29 (3) ◽  
pp. 303-310 ◽  
Author(s):  
Daniel Kim-wan Young ◽  
Petrus Yat-nam Ng ◽  
Daphne Cheng
Keyword(s):  
Quality Of Life ◽  
Treatment Group ◽  
Controlled Trial ◽  
T Test ◽  
World Health ◽  
Control Group ◽  
World Health Organization Quality ◽  
Life Measure ◽  
Health Organization

Purpose: This research study aims to evaluate the effectiveness of a psychoeducation group, which is founded on an Eastern approach to health care, in improving the quality of life of Chinese people with mild cognitive impairment (PwMCI). Method: In a randomized controlled trial (RCT), 40 Chinese PwMCI were randomly assigned to either a 10-session psychoeducation group or the control group. Results: A paired sample t test indicated that the treatment group ( n = 18) showed significant improvement in their World Health Organization Quality of Life Measure (WHOQOL) score, while the control group ( n = 22) did not. Moreover, an independent t test showed that the treatment group was more effective than the control group to improve their WHOQOL score. A reduction in the depressive symptoms was related to the improvement in WHOQOL score. Conclusions: This RCT provides evidence to support the feasibility and effectiveness of psychoeducation groups for improving the overall quality of life of PwMCI.

Cognitive Therapy and Recovery from Acute Psychosis: a Controlled Trial

1996 ◽  
Vol 169 (5) ◽  
pp. 593-601 ◽  
Author(s):  
Val Drury ◽  
Max Birchwood ◽  
Ray Cochrane ◽  
Fiona MacMillan
Keyword(s):  
Cognitive Therapy ◽  
Controlled Trial ◽  
Self Report ◽  
Control Group ◽  
Positive Symptoms ◽  
State Assessments ◽  
Acute Psychosis ◽  
Affective Psychosis ◽  
Residual Symptoms ◽  
The Uk

BackgroundThe application of cognitive therapy (CT) to psychosis is currently being developed in the UK. This paper reports a trial of CT in acute psychosis with the objective of hastening the resolution of positive symptoms and reducing residual symptoms.MethodOf 117 patients with acute non-affective psychosis, 69 satisfied inclusion criteria and 40 proceeded to stratified randomisation. The experimental intervention involving individual and group CT was compared with a group receiving matched hours of therapist input providing structured activities and informal support; routine pharmacotherapy was provided by clinicians blind to group allocation. Patients were monitored weekly using self-report and mental state assessments during admission and over the subsequent nine months.ResultsBoth groups showed a decline in positive symptoms but this was more marked in the CT group (P < 0.001). At 9 months 5% of the CT group, v. 56% of the control group, showed moderate or severe residual symptoms.ConclusionCT appears to be a potent adjunct to pharmacotherapy and standard care for acute psychosis. Issues concerning internal and external validity of the study and opportunities for further research are discussed.

Sign in / Sign up

Export Citation Format

Share Document