scholarly journals Efficacy of a combination of regional methods of anesthesia with general anesthesia in corneal transplantation

2021 ◽  
Vol 17 (4) ◽  
pp. 69-73
Author(s):  
N.V. Mynka ◽  
Yu.Yu. Kobelyatsky
Keyword(s):  
Postoperative Pain ◽  
Pain Relief ◽  
Gas Exchange ◽  
General Anesthesia ◽  
Corneal Transplantation ◽  
Pain Syndrome ◽  
Pterygopalatine Fossa ◽  
Balanced Anesthesia ◽  
Intraoperative Pain ◽  
Group B

Background. Despite the significant development of modern anesthesiology, the pain relief of surgical patients is still unsatisfactory. Inadequate pain management causes psychological discomfort and complications. The combination of general anesthesia with various options for local anesthesia allows one to get closer to solving the problem of pain. The aim of the study was to compare the effect of multicomponent balanced anesthesia (intravenous + inhalation) and multicomponent balanced anesthesia, supplemented by pterygopalatine fossa blockade on the safety and efficacy of anesthesia for corneal transplantation. Materials and methods. The study included 73 patients, divided into two groups. Group С received multicomponent balanced anesthesia, group B — pterygopalatine fossa blockade additionally. The main criteria for evaluating the results of the study were: stability of hemodynamics and gas exchange during surgery, the severity of intraoperative pain syndrome by recording the analgesia nociception index, the severity of postoperative pain syndrome and the incidence of postoperative nausea and vomiting. Results. Both schemes of anesthetic management made it possible to avoid pronounced fluctuations in hemodynamic and gas exchange parameters at all stages of the study. Analyzing the severity of intraoperative pain, we found that in group С, pain relief could be considered insufficient during the first 7 minutes of the most traumatic stage of the operation, while in group B the analgesia nociception index did not decrease below 50. Statistically significant differences were obtained during 8 out of 10 minutes of the stage. Analysis of the pain relief quality in the postoperative period has shown that the level of pain according to the visual analogue scale upon awakening was equal to 0 in both groups, at the next three stages of the study (two and six hours after surgery and on the morning of the next day) the level pain in group C was significantly higher than in group B. Conclusions. The addition of regional blockade to multicomponent general anesthesia allows for adequate control of postoperative pain without compromising the safety profile.

scholarly journals The experience of using dexmedetomidine as an adjuvant of anesthesia in ophthalmic surgery

2021 ◽  
Vol 26 (1) ◽  
pp. 128-135
Author(s):  
N.V. Mynka ◽  
Yu.Yu. Kobelyatskyy
Keyword(s):  
Postoperative Pain ◽  
Pain Relief ◽  
Postoperative Nausea ◽  
Corneal Transplantation ◽  
Postoperative Nausea And Vomiting ◽  
Pain Syndrome ◽  
Nausea And Vomiting ◽  
Ophthalmic Surgery ◽  
Intraoperative Pain ◽  
Group D

Various techniques are applied to reduce the severity of postoperative pain and discomfort in patients. The purpose of this research work was to evaluate the effectiveness and safety of Dexmedetomidine as an adjuvant of anesthesia in ophthalmic surgery. The study included 80 patients who underwent  corneal transplantation on the basis of Dnepropetrovsk Regional Clinical Ophthalmologic Hospital. Patients were divided into 2 groups: control (group K) – 30 men and main (group D) – 50 ones. Multicomponent balanced anesthesia was applied in both groups. Sibazone was administered as the sedative medicine in the group K, Dexmedetomedin was administered in the group D. The main criteria for evaluating the research results were hallmarked: hemodynamic stability during surgery, the amount of administered opiates, the severity of intraoperative pain syndrome by evaluating the ANI index (ANI – analgesia nociception index), the severity of postoperative pain syndrome and the frequency of postoperative nausea and vomiting (PONV). Both schemes of anesthesia allowed avoiding pronounced fluctuations in hemodynamic parameters and gas exchange at all stages of the study. Analyzing the severity of intraoperative pain, we found that in group K pain relief could be considered insufficient during the first 7 minutes of the most traumatic stage of the surgery, while in group D the ANI index did not fall below 50. Statistically significant differences were obtained on minute 1, 2, 5, 6, and 7 of the surgery. The number of episodes of insufficient anesthesia during the most traumatic stage of the surgery in group K was statistically significantly higher than in group D. Analyzing the quality of pain relief in the postoperative period it was determined, that the level of pain on the Visual Analog Scale (VAS) after awakening in both groups was equal to 0. At the next three stages of the study (2 hours, 6 hours after surgery, and the next morning), the level of pain in group K was significantly higher than in group D. In addition, it was determined that the need for narcotic analgesics and the number of episodes of postoperative nausea and vomiting in group K was statistically significantly higher than in group D. These given data allow us to conclude that Dexmedetomedin is the effective adjuvant of the anesthesia for corneal transplantation.

scholarly journals Incidence of Acute and Chronic Post-Thoracotomy Pain in Pediatric Patients

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 642
Author(s):  
Giuliano Marchetti ◽  
Alessandro Vittori ◽  
Fabio Ferrari ◽  
Elisa Francia ◽  
Ilaria Mascilini ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Pediatric Patients ◽  
Pain Syndrome ◽  
Intercostal Nerve ◽  
Anesthetic Technique ◽  
Intercostal Nerve Block ◽  
Thoracic Epidural ◽  
Burning Pain ◽  
Significant Difference ◽  
Group B

We studied acute and chronic pain in pediatric patients who underwent thoracotomy for benign disease with a follow-up of at least three months. A telephone interview investigated about the presence of pain and the analgesic therapy in progress. The results were compared with the anesthetic technique, postoperative pain and the adequacy of pain therapy, both during the first week after surgery and at the time of interview. Fifty-six families consented to the study. The mean age of the children at surgery was 2.9 ± 4.5 years, while at the time of the interview was 6.5 ± 4.4 years. We performed different anesthetic strategies: Group A: general anesthesia (36 pts); Group B: general anesthesia and thoracic epidural (10 pts); Group C: general anesthesia and intercostal nerve block (10 pts). During the immediate postoperative period, 21 patients (37.5%) had at least one painful episode. At the time of interview, 3 children (5.3%) had moderate chronic neuropathic (burning) pain on surgical scar. There was no statistically significant difference between the type of anesthesia and the incidence and severity of acute post-operative pain. Despite its limitations, this study confirms the low incidence of chronic post-thoracotomy pain syndrome in children.

scholarly journals Tumescent local anesthesia as an alternative to general anesthesia in release of post-burn neck contracture and skin graft harvesting: A comparative study

2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Mukesh Kumar Prasad ◽  
Payal Jain ◽  
Rohit Kumar Varshney ◽  
Aditi Khare ◽  
Gurdeep Singh Jheetay
Keyword(s):  
Postoperative Pain ◽  
Pain Relief ◽  
Blood Loss ◽  
General Anesthesia ◽  
Local Anesthesia ◽  
Skin Graft ◽  
Tumescent Local Anesthesia ◽  
Graft Harvest ◽  
Contracture Release ◽  
Split Skin

Background: Anesthetic management of severe post burn neck contracture is difficult, demanding due to fixed flexion deformity of neck, incomplete oral occlusion and insufficient mouth opening leading to difficulty in intubation. Patients undergoing contracture release, skin graft harvest under general anesthesia (GA) were compared with patients undergoing the same surgery under tumescent local anesthesia (TLA) technique. Methodology: Twenty-one patients with post burn neck contracture undergoing contracture release with split skin grafting under GA were compared with twenty-one patients undergoing the same surgery under TLA. Post-operative pain and satisfaction were assessed using 10 cm VAS (Visual Analogue Scale).  Results: Demographic profile was comparable in both groups. Changes in intra-operative vital parameters remained insignificant. The average volume of tumescent solution used was 254.76 + 49.05ml. Blood loss was significantly decreased, postoperative pain relief was more than sixteen hours in thirteen patients and extended beyond twenty-four hours in six patients in the TLA group. Time for the first rescue analgesia was significantly lesser in the GA group and the average dose of injection tramadol used in the GA group was significantly higher within the first 24 h. Overall satisfaction in the TLA group was significantly higher than in the GA group. Conclusion: TLA can be used as sole technique for release of post burn neck contracture and harvest of split skin grafts with less blood loss and significantly better postoperative pain relief avoiding complications of general anesthesia. Key words: Tumescent local anesthesia; Post burn neck contracture; Skin graft harvest; General anesthesia Citation: Prasad MK, Jain P, Varshney RK, Khare A, Jheetay GS. Tumescent local anesthesia as an alternative to general anesthesia in the release of post-burn neck contracture and skin graft harvesting: A comparative study. Anaesth. Pain intensive care 2021;25(1):34–39. DOI: 10.35975/apic.v25i1.1434 Received: 18 February 2020, Reviewed: 16 March 2020, Accepted: 30 April 2020

Changes in management of patients with diseases of musculoskeletal system and joints

2021 ◽  
pp. 36-40
Author(s):  
A. L. Vertkin ◽  
A. N. Barinov ◽  
G. Yu. Knorring
Keyword(s):  
Side Effects ◽  
Pain Relief ◽  
Severe Pain ◽  
Pain Syndrome ◽  
Cooperative Action ◽  
Pain Syndromes ◽  
Adequate Pain Relief ◽  
Inflammatory Drugs ◽  
Group B ◽  
Group B Vitamins

Pain syndrome accompanies the vast majority of diseases; therefore, the issues of adequate pain relief remain topical not only for urgent conditions, but also for everyday medical practice. Modern and changed in recent years approaches to the appointment of anesthetic therapy should take into account not only the pathogenetic mechanisms of the development of pain syndrome in a particular patient, but also the need to use drug combinations. This allows for the potentiation of the analgesic effect, reduction of effective dosages of individual drugs and minimization of side effects. In case of severe pain syndrome in the presence of signs of impaired nociception, neuropathic and muscle-fascial pain syndromes, the use of non-steroidal anti-inflammatory drugs in conjunction with group B vitamins is justified. The article considers the pathogenetic details of such a combination therapy, reveals the mechanisms of the cooperative action of the proposed combination of drugs.

scholarly journals ROLE OF TOPICAL TREATMENT OF PAIN SYNDROME IN PATIENTS AFTER HEMORROIDECTOMY

2019 ◽  
Vol 18 (4) ◽  
pp. 110-115
Author(s):  
V. V. Ivanov ◽  
I. S. Lebedev ◽  
L. A. Blagodarny
Keyword(s):  
Retrospective Study ◽  
Postoperative Pain ◽  
Pain Relief ◽  
Pain Syndrome ◽  
Main Group ◽  
Analog Scale ◽  
Postoperative Control ◽  
Opioid Receptor Antagonists ◽  
Local Use

AIM: to estimate efficacy of local use of fluocortolone pivalate combined with lidocaine for postoperative pain after excisional hemorrhoidectomy.PATIENTS AND METHODS: two-hundred patients were included in retrospective study. All patients underwent excisional hemorrhoidectomy. Patients were divided in two groups, each group included 100 patients comparable in demographics, hemorrhoids stage. Traditional postoperative systemic pain relief was used in both groups and included NSAIDs and opioid receptor antagonists. The main group included patients with postoperative additional local use of fluocortolone pivalate in combination with lidocaine in operative theatre, every day after during postoperative control examination and after each defecation up to 7 days after surgery. The pain intensity was estimated using visual analog scale (VAS).RESULTS: on the 1st day after surgery pain was less intensive in the main group (1.57 vs 3.24; p<0,05), as well as on the 3d day (0,91 vs 2.48; p<0,05) and on 7th day (0.63 vs 1.12; p<0,05).CONCLUSION: local use of fluocortolone pivalate combined with lidocaine reduces postoperative pain twice.

scholarly journals Intraperitoneal analgesia for postoperative pain relief after laparoscopic gynecological surgeries

2017 ◽  
Vol 6 (11) ◽  
pp. 5099 ◽  
Author(s):  
Basant Kumar Pati
Keyword(s):  
Side Effects ◽  
Postoperative Pain ◽  
Pain Relief ◽  
Visual Analogue Score ◽  
Local Anaesthetics ◽  
Safe Method ◽  
Analgesic Consumption ◽  
Post Operative Pain ◽  
Intraperitoneal Instillation ◽  
Group B

Background: Though laparoscopic gynaecological surgeries are less invasive and produces less post-operative pain, post-laparoscopy pain is still a concern. Intraperitoneal (IP) instillation of local anaesthetics has been shown to minimize the postoperative pain after laparoscopic surgeries. This study was conducted to compare the efficacy of intraperitoneal instillation of dexmedetomidine with bupivacaine and bupivacaine alone in reducing postoperative pain.Methods: 60 patients, enrolled for gynaecological laparoscopic surgeries were divided randomly into two groups of 30 each. Group B: Bupivacaine (30 ml, 0.25%) with 2 ml normal saline was instilled prior to removal of trocars, and Group BD: Bupivacaine (30 ml, 0.25%) with dexmedetomidine (1 mcg/kg, diluted to 2 ml) was instilled prior to removal of trocars. In postoperative period, Visual Analogue Score (VAS) was recorded up to 24 hours. Postoperative analgesic requirements, and side effects were recorded.Results: The Visual Analogue Score (VAS) during the first postoperative 24 hours was significantly lower in group BD compared to group B. Time to first analgesia required was delayed and total analgesic consumption was lower in group BD compared to group B which was statistically significant.Conclusions: Intraperitoneal instillation of dexmedetomidine with bupivacaine is an effective and safe method for reducing pain after laparoscopic gynaecological surgeries.

scholarly journals Effect of topical bupivacaine on post-tonsillectomy pain relief in children

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Musa Kallamu Suleiman ◽  
Abdulkarim Aitek Abdullahi ◽  
Alhassan Datti Mohammed ◽  
Kufre Robert Iseh ◽  
Abdulrahman Aliyu ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Pain Relief ◽  
Pain Intensity ◽  
Normal Saline ◽  
Pain Scale ◽  
Inclusion Criteria ◽  
Tonsillar Fossa ◽  
The Difference ◽  
Group B

Tonsillectomy is a common surgery performed in paediatric otorhinolaryngology and is usually accompanied by considerable postoperative pain. Earlier literature has shown the use of topical bupivacaine for post-tonsillectomy pain relief to be promising. This study was conducted to evaluate the efficacy of topical bupivacaine application on post-tonsillectomy pain relief. Fifty consenting patients scheduled for tonsillectomy that met the inclusion criteria were enrolled in the study and assigned into two groups of 25 patients each. Group B had their tonsillar fossa packed with 0.5% bupivacaine soaked gauze for 5 minutes while Group S had normal saline. Pain intensity was measured at 1, 2, 4, 12 and 24 hours postoperatively, using the Faces Pain Scale- Revised (FPS-R). Mean scores for groups B and S at 1, 2, 4, 8, 12, 24 hours were 1.96±1.17, 2.40±0.82, 2.8±1.0, 2.88±1.17, 3.08±0.99, and 3.04±1.02 and 3.36±1.38, 4.72±1.62, 3.92±1.35, 3.76±1.45, 4.00±1.41, 3.38±0.98 respectively. The difference was significant at 1 and 2 hours only (P≤0.05). Post-tonsillectomy pain was reduced in the first two hours by application of bupivacaine soaked gauze.

scholarly journals Comparison of intraincisional and intraperitoneal infiltration of local anaesthetic in laparoscopic cholecystectomy to control early postoperative pain.

2021 ◽  
Vol 28 (02) ◽  
pp. 192-196
Author(s):  
Nadia Bano ◽  
Nazim Hayat ◽  
Saira Saleem ◽  
Farhan Javaid ◽  
Ayesha Rehman ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Pain ◽  
Pain Relief ◽  
Local Anaesthetic ◽  
Early Postoperative Period ◽  
P Value ◽  
Analgesic Requirement ◽  
Rescue Analgesia ◽  
Group A ◽  
Group B

Objective: To compare the effects of intraincisional and intraperitoneal infiltration of local anaesthetic to relieve early postoperative pain in laparoscopic cholecystectomy. Study Design: Randomized Control Trial. Setting: Department of Anaesthesia and Surgery, Madinah Teaching Hospital Faisalabad. Period: July 2017 to March 2018. Material & Methods: A sample of 100 patients with American Society of Anaesthesiologists Physical status (ASA) I and II, undergoing laparoscopic cholecystectomy were selected using simple random sampling technique. Patients were randomly assigned into groups A and B. Group A patients received intraperitoneal infiltration of 20 ml solution of 0.25% bupivacaine and group B patients received intraincisional infiltration of 20 ml solution of 0.25% bupivacaine. Results:  Demographic characteristics were not significantly different in both groups. Our study showed that Group A patients had better pain relief as compared to group B patients. Visual analogue score (VAS) for pain relief at 0, 3,6,12 and 24 hours was statistically different in both groups. The requirement of rescue analgesia between group A and B was found to be12% and 38% which is statically significant (p value 0.003). Conclusion: intraperitoneal infiltration of Bupivacaine offers better postoperative pain relief after laparoscopic cholecystectomy and is associated with less analgesic requirement in early postoperative period.

scholarly journals Efficiency of ultrasound guided lower limb peripheral nerve blocks in perioperative pain management for knee arthroscopy in children: A randomized study

2016 ◽  
Vol 69 (1-2) ◽  
pp. 5-10
Author(s):  
Dragan Marinkovic ◽  
Jovana Simin ◽  
Biljana Draskovic ◽  
Ivana Kvrgic ◽  
Marina Pandurov
Keyword(s):  
Postoperative Pain ◽  
Peripheral Nerve ◽  
General Anesthesia ◽  
Lower Limb ◽  
Knee Arthroscopy ◽  
Opioid Analgesics ◽  
Ultrasound Guided ◽  
Nerve Blocks ◽  
Peripheral Nerve Blocks ◽  
Group B

Introduction. Ultrasound guided lower limb peripheral nerve blocks are efficient for perioperative pain treatment in children. The aim was to see if lower limb peripheral nerve blocks reduced the amount of propofol and opioid analgesics used intraoperatively, as well as the level of pain and consumption of systemic analgesics postoperatively. Material and Methods. A randomized, prospective clinical trial was carried out. It included 60 children between 11 and 18 years of age scheduled for elective knee arthroscopy. The patients were divided into two groups. Group A received general anesthesia, group B received lower limb peripheral nerve blocks with sedation or general anesthesia. Postoperative level of pain was assessed using visual analogue scale. Results. Less propofol and fentanyl was used to induce and maintain anesthesia in group B (p<0.001). The level of postoperative pain was significantly lower in group B (p<0.001), as well as the postoperative consumption of analgesics (p<0.001). As mahbny as 47% of the patients were discharged without receiving any analgesics postoperatively. The average duration of peripheral nerve blocks was 468 minutes. Conclusions. Ultrasound guided lower limb peripheral nerve blocks are an efficient technique of regional anesthesia in children. They reduce the amount of general anesthetics and opioid analgesics needed intraoperatively as well as the level of postoperative pain and consumption of analgesics postoperatively.

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