scholarly journals Diabetes mellitus and atherosclerosis. The role of inflammatory processes in pathogenesis (literature review)

2017 ◽  
Vol 13 (7) ◽  
pp. 486-498 ◽  
Author(s):  
L.K. Sokolova ◽  
V.M. Pushkarev ◽  
V.V. Pushkarev ◽  
O.I. Kovzun ◽  
M.D. Tronko
Keyword(s):  
Diabetes Mellitus ◽  
Literature Review ◽  
Inflammatory Processes

scholarly journals The role of a school nurse in the care of a child with diabetes mellitus type 1 - the perspectives of patients and their parents: Literature review

2018 ◽  
Vol 57 (3) ◽  
pp. 166-174
Author(s):  
Anna Stefanowicz ◽  
Joanna Stefanowicz
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Blood Glucose ◽  
Literature Review ◽  
Type 1 Diabetes Mellitus ◽  
Metabolic Control ◽  
School Nurse ◽  
Parents And Children

Abstract Introduction The aim of this literature review was to explore the views of parents and children with type 1 diabetes mellitus regarding having a school nurse. Methods Six databases were selected for the analysis. The research strategy was based on the PICO model. The research participants were children with type 1 diabetes mellitus and/or their parents. Results The present review of research papers includes 12 publications. The majority of works deal with the perspectives of children with type 1 diabetes and their parents on various aspects related to the role of a school nurse in the care of a child with type 1 diabetes: the presence of a school nurse; the role of a school nurse in the prevention and treatment of hypoglycaemia, in performing the measurements of blood glucose, and in insulin therapy; the role of a nurse in improving metabolic control of children with type 1 diabetes; a nurse as an educator for children with type 1 diabetes, classmates, teachers, teacher’s assistants, principals, administrators, cafeteria workers, coaches, gym teachers, bus drivers, and school office staff; a nurse as an organiser of the care for children with type 1 diabetes. Conclusions According to parents and children with type 1 diabetes mellitus, various forms of school nurse support (i.e., checking blood glucose, giving insulin, giving glucagon, treating low and high blood glucose levels, carbohydrate counting) are consistently effective and should have an impact on the condition, improvement of metabolic control, school activity and safety at school.

scholarly journals Emerging role of interleukin-1 in cardiovascular diseases

2009 ◽  
pp. 481-498
Author(s):  
B Vicenová ◽  
V Vopálenský ◽  
L Burýšek ◽  
M Pospíšek
Keyword(s):  
Rheumatoid Arthritis ◽  
Diabetes Mellitus ◽  
Cardiovascular Diseases ◽  
Cardiovascular Events ◽  
Current Knowledge ◽  
Interleukin 1 ◽  
Proinflammatory Mediators ◽  
Inflammatory Processes ◽  
Higher Eukaryotes

There is an increasing evidence linking dysbalance between various proinflammatory mediators and higher risk of cardiovascular events and pathologies. Likewise, some of the cardiovascular diseases lately appeared to have an autoimmune component. Interleukin-1 (IL-1), a master regulator of diverse inflammatory processes in higher eukaryotes and the key player in numerous autoimmune disorders including rheumatoid arthritis, diabetes mellitus or systemic sclerosis, has recently been proved to be involved in development of several cardiovascular diseases as well. This report aims to give a summary on current knowledge about the IL-1 signaling pathways and about the implication of IL-1 and the IL-1 receptor antagonist (IL-1Ra) in some of the diseases of the cardiovascular system.

scholarly journals Erectile dysfunction in men with diabetes (literature review). Part 2

2021 ◽  
Vol 17 (6) ◽  
pp. 513-519
Author(s):  
Е.V. Luchytskiy ◽  
V.E. Luchytskiy
Keyword(s):  
Diabetes Mellitus ◽  
Erectile Dysfunction ◽  
Literature Review ◽  
Clinical Manifestations ◽  
Penile Prosthesis ◽  
Epidemiological Studies ◽  
Diagnosis And Treatment ◽  
Pde5 Inhibitors ◽  
Surgical Methods

The second part of review article highlights modern views on the diagnosis and treatment of erectile dysfunction (ED) in men with diabetes mellitus (DM). Google Scholar and PubMed databases were used to search for literature sources. The role of comorbid diseases in the development of ED in men with diabetes mellitus has been shown. The generalized data on the main clinical manifestations of erectile dysfunction, methods of its diagnosis and treatment are given. A number of epidemiological studies over the past 20 years have found that erectile dysfunction in men with diabetes may be an early marker of cardiovascular complications. Thus, in the algorithm for the diagnosis of ED in patients with diabetes it is necessary to conduct a thorough examination of the cardiovascular system. The article describes modern therapeutic and surgical methods of ED treatment. Numerous literature sources indicate an important role of the correction of androgen deficiency in men with type 2 diabetes to enhance the effectiveness of phosphodiesterase type 5 (PDE5) inhibitors. The literature review shows the data on the emergence of new PDE5 inhibitors, which have a higher selectivity compared to existing ones that provides a better therapeutic effect and reduces the frequency and severity of side effects. The modern algorithm for the treatment of ED in men involves the sequential stages of using different treatments. The last link of therapy, in case of inefficiency of the previous ones, is penile prosthesis. Implantation of three-piece penile prosthesis is an effective method of ED treatment. The use of this method in patients with severe forms of ED on the background of diabetes, in case of ineffectiveness of PDE5 inhibitors and intracavernous injections of vasoactive drugs, is considered promising.

scholarly journals Diabetes mellitus and schizophrenia: Historical perspective

2004 ◽  
Vol 184 (S47) ◽  
pp. s64-s66 ◽  
Author(s):  
Dora Kohen
Keyword(s):  
Diabetes Mellitus ◽  
Literature Review ◽  
Glucose Tolerance ◽  
Mental Disorder ◽  
Historical Perspective ◽  
Mental Illnesses ◽  
Dementia Praecox ◽  
Metabolic Factors ◽  
Antipsychotic Medications

BackgroundAlthough recent research has focused on the possible role of antipsychotic medications in the development of diabetes mellitus, studies conducted in the pre-neurolepticera suggest that schizophrenia itself might predispose individuals to diabetes.AimsTo test the hypothesis that diabetes mellitus is an integral part of schizophrenia.MethodHistorical literature review.ResultsMany people with severe mental illnesses, including dementia praecox, showed abnormal responses to insulin and diabetes-like glucose tolerance curves long before the advent of phenothiazines. Early studies with chlorpromazine suggested that a latent tendency towards diabetes in patients with schizophrenia could be unmasked by this treatment.ConclusionsDiabetes and disturbed carbohydrate metabolism maybe an integral part of schizophrenia. Further research is required to explain how metabolic factors, medications and lifestyle factors might precipitate diabetes in patients with this mental disorder.

scholarly journals Stress and the genesis of diabetes mellitus in schizophrenia

2004 ◽  
Vol 184 (S47) ◽  
pp. s72-s75 ◽  
Author(s):  
Timothy G. Dinan
Keyword(s):  
Diabetes Mellitus ◽  
General Population ◽  
Literature Review ◽  
Antipsychotic Drugs ◽  
Hypothalamic Pituitary Adrenal ◽  
Onset Of Diabetes

BackgroundThe incidence of diabetes mellitus is higher in patients with schizophrenia than in the general population. Antipsychotic drugs have been implicated in the development of diabetes, but as non-medicated patients with schizophrenia have high rates of diabetes it is likely that factors other than medication are involved.AimTo examine the role of stress in the emergence of diabetes mellitus in patients with schizophrenia.MethodSelective literature review.ResultsA model is developed suggesting that patients with schizophrenia show overactivation of both the hypothalamic–pituitary–adrenal and sympathoadrenal medullary axes, manifested by increased production of cortisol and adrenaline. Both of these hormones are known to be diabetogenic and are proposed as playing a part in the onset of diabetes mellitus in schizophrenia.ConclusionsStress has an important role in the onset of schizophrenia and may also play a part in relapse. Further research is needed to clarify the extent to which stress accounts for the genesis of diabetes in such patients.

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