scholarly journals IMPACT OF ACNE VULGARIS ON A PERSON’S QUALITY OF LIFE AND IT’S CORRELATION WITH THE CLINICAL SEVERITY PRE AND POST-DRUG THERAPY

2022 ◽  
pp. 13-16
Author(s):  
SWOPNA PHUKAN ◽  
SAHELI DAS
Keyword(s):  
Quality Of Life ◽  
Drug Therapy ◽  
Observational Study ◽  
Acne Vulgaris ◽  
Ethics Committee ◽  
Clinical Severity ◽  
Grading System ◽  
Institutional Ethics

Objective: The aim of the study is to assess the therapeutic efficacy of drugs used in acne vulgaris by measuring the severity of acne using the Global Acne Grading System score (GAGS) and Cardiff Acne Disability Index (CADI) questionnaire score pre and post-drug therapy. Methods: The present study was conducted in the Department of Dermatology after getting approval from the Institutional Ethics Committee (No MC/190/2007/Pt1/MAR-2019/PG/123) dated 10/04/2019. It was an observational study for a period of 1 y. 172 patients were enrolled in the study. Patients were divided into 4 grades depending on their clinical manifestation. The severity of acne vulgaris and the quality of life were measured using the GAGS scale and the CADI questionnaire, respectively at the first visit and at the follow-up visit in all the grades of acne vulgaris. A correlation was done between the GAGS and the CADI score at the follow-up visit in all grades of acne. Results: It was observed that the GAGS score and the CADI score was significantly improved at the F/U visit (p<0.05) as compared to baseline in all the 4 grades of acne. A correlation between GAGS score and QoL using CADI scale was done using Pearson Parametric Correlation Test. In none of the groups, the correlation was significant (p>0.05). Conclusion: We can conclude from our study that following treatment with drugs, the clinical severity of acne decreased and there was also a significant improvement in the quality of life of patients.

scholarly journals Psychosocial Impact of Acne: A Community Based Cross Sectional Study

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Mohammad Sarwar Mir
Keyword(s):  
Quality Of Life ◽  
Social Impact ◽  
Acne Vulgaris ◽  
Clinical Severity ◽  
Age Group ◽  
Cross Sectional ◽  
Severe Acne ◽  
Number Of Patients ◽  
The Impact

Background: It is well-known that acne vulgaris is a common malady of adolescence and is easily recognized Objective: To evaluate the level of impact among acne patients on their quality of life. Methods: A total of 200 patients studied. Acne severity was graded using Global Acne Grading System (GAGS) after the clinical diagnosis. All the patients went through self-administered questionnaire of Cardiff Acne Disability Index (CADI) to fill out, to assess the reflection of patients’ experiences and perceptions. Result: Out of 200 patients, 114(57.0%) were females and 86(43.0%) were males. The maximum number of patients was in the age group of 16-20 years (142/200, 71%). Out of total 86 males, 50 (58.3%) had moderate to severe acne, whereas 62(54.38%) females had such a severe acne. 50.87% (58/114) of females had high CADI scores in comparison to only 27.9(24/86) of males. The impact on quality of life was more in the age-group of 21-30 years even though in this age group clinical severity of acne was mild to moderate only. Conclusion: Study found that individuals with acne had profound emotional, as well as, social impact on their quality of life.

scholarly journals Clinical Evolution and Quality of Life in Clinically Based COPD Chronic Bronchitic and Emphysematous Phenotypes: Results from the 1-Year Follow-Up of the STORICO Italian Observational Study

2021 ◽  
Vol Volume 16 ◽  
pp. 2133-2148
Author(s):  
Francesco Blasi ◽  
Raffaele Antonelli Incalzi ◽  
Giorgio Walter Canonica ◽  
Pietro Schino ◽  
Giuseppina Cuttitta ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Clinical Evolution

Long-term mortality and quality of life after septic shock: a follow-up observational study

2013 ◽  
Vol 39 (5) ◽  
pp. 881-888 ◽  
Author(s):  
Nicolas Nesseler ◽  
Anne Defontaine ◽  
Yoann Launey ◽  
Jeff Morcet ◽  
Yannick Mallédant ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Septic Shock ◽  
Observational Study ◽  
Long Term Mortality

scholarly journals ASSESSMENT OF DERMATOLOGICAL LIFE QUALITY INDEX AND CARDIFF ACNE DISABILITY INDEX IN PATIENTS ATTENDING OUR COLLEGE OPD

2020 ◽  
pp. 1-2
Author(s):  
Arshi Farista* ◽  
Sowmya Manangi
Keyword(s):  
Quality Of Life ◽  
Prospective Study ◽  
Older Patients ◽  
Quality Index ◽  
Acne Vulgaris ◽  
Life Quality ◽  
Grading System ◽  
Psychosocial Sequelae ◽  
The Impact

Background:Acne vulgaris is known to impair many aspects of quality of life. Acne is a common problem in adolescent children and adults. Aims: Astudy was undertaken to measure the impairment of quality of life of patients of acne vulgaris and correlate it with the severity of lesions. This study was aimed to assess the impact of acne and its sequelae on the DQLI and CADI Materials and methods: This was a hospital based prospective study done between September 2018 to march 2019 on 170 patients coming to our college opd. Acne vulgaris and its sequelae were graded using global acne grading system. The DLQI and CADI score were recorded by giving the patients a set of questionnaire. General use of cosmetics and other history related to diet and habits were noted. Results: the over all CADI SCORE were low indicating a mild impairement. Out of 170 patients 110 were girls and 60 were boys. Almost 95% patients had applied fair and lovely. The severity of acne progressively lessened in older patients. Mean DLQI score was 5.3. DQLI score were statistically inuenced by the age of the patient , duration of andgrade of acne , acne scars and post hyperpigmentation. Conclusion: the study showed CADI SCORE AND DLQI were low indicating mild imapirement. Assurance and counseling along with early treatment of acne vulgaris are important to reduce disease-related psychosocial sequelae and increase the efcacy of treatment.

scholarly journals Prevalence and severity of acne vulgaris and its impact on quality of life in adolescents

2021 ◽  
Vol 10 (14) ◽  
pp. e241101422084
Author(s):  
Ludmilia Rodrigues Lima Neuenschwander Penha ◽  
Rosely Fontes Grisotto ◽  
Aldair Darlan Santos-de-Araújo ◽  
Caio Rodriguez Lima Neuenschwander Penha ◽  
Ilana Mirian Almeida Felipe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acne Vulgaris ◽  
Grading System

Acne é uma condição genético-hormonal caracterizada por manchas moderadas a graves que ocorrem devido ao acúmulo de sebo nos folículos capilares por meio da hiperqueratinização folicular. Pode ser inflamatório ou não inflamatório e é autolimitado, o que significa que tende a evoluir para resolução naturalmente. No entanto, os casos mais graves podem exigir tratamento prolongado para evitar o agravamento da condição e cicatrizes permanentes. O objetivo deste estudo foi avaliar o impacto da acne na qualidade de vida de adolescentes e determinar associações com estilo de vida e hábitos alimentares. Estudo descritivo, analítico e transversal realizado com adolescentes brasileiros de 14 a 18 anos de escolas públicas. A coleta de dados envolveu a aplicação de um questionário com informações sociodemográficas, o Global Acne Grading System (GAGS) e o Cardiff Acne Disability Index (CADI). A prevalência de acne foi de 100%. De acordo com o GAGS, 76,63% tinham acne leve, 21,99% acne moderada e 1,37% acne grave. Com base no escore CADI, 70,45% da amostra apresentou impacto leve, 25,12% impacto moderado e 3,44% impacto grave. A análise estatística dessas variáveis revelou resultados significativos (p <0,05), mas o coeficiente de Pearson revelou uma correlação fraca (r = 0,265). Os presentes achados demonstram que o impacto da acne na qualidade de vida dos adolescentes é diretamente proporcional à sua gravidade. É necessário disseminar o conhecimento sobre o tema para a população para diminuir o impacto dessa condição.

scholarly journals Clinical, radiological and functional outcomes in patients with SARS-CoV-2 pneumonia: a prospective observational study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Pietro Gianella ◽  
Elia Rigamonti ◽  
Marco Marando ◽  
Adriana Tamburello ◽  
Lorenzo Grazioli Gauthier ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Function ◽  
Observational Study ◽  
Ct Scan ◽  
Prospective Observational Study ◽  
Lung Function Tests ◽  
Medium Term ◽  
Function Tests

Abstract Background All over the world, SARS-CoV-2 pneumonia is causing a significant short-term morbidity and mortality, but the medium-term impact on lung function and quality of life of affected patients are still unknown. Methods In this prospective observational study, 39 patients with SARS-CoV-2 pneumonia were recruited from a single COVID-19 hospital in Southern Switzerland. At three months patients underwent radiological and functional follow-up through CT scan, lung function tests, and 6 min walking test. Furthermore, quality of life was assessed through self-reported questionnaires. Results Among 39 patients with SARS-CoV-2 pneumonia, 32 (82% of all participants) presented abnormalities in CT scan and 25 (64.1%) had lung function tests impairment at three months. Moreover, 31 patients (79.5%) reported a perception of poor health due to respiratory symptoms and all 39 patients showed an overall decreased quality of life. Conclusions Medium-term follow up at three months of patients diagnosed with SARS-CoV-2 pneumonia shows the persistence of abnormalities in CT scans, a significant functional impairment assessed by lung function tests and a decreased quality of life in affected patients. Further studies evaluating the long-term impact are warranted to guarantee an appropriate follow-up to patients recovering from SARS-CoV-2 pneumonia.

scholarly journals Assessment and management of sexual dysfunction in the context of depression

2017 ◽  
Vol 8 (1) ◽  
pp. 13-23 ◽  
Author(s):  
Pratap R. Chokka ◽  
Jeffrey R. Hankey
Keyword(s):  
Quality Of Life ◽  
Drug Therapy ◽  
Sexual Dysfunction ◽  
Sexual Functioning ◽  
Common Side Effect ◽  
Evidence Based ◽  
Sexual Symptoms ◽  
Bidirectional Relationship

Sexual dysfunction (SD) is pervasive and underreported, and its effects on quality of life are underestimated. Due in part to its bidirectional relationship with depression, SD can be difficult to diagnose; it is also a common side effect of many antidepressants, leading to treatment noncompliance. While physicians often count on patients to spontaneously report SD, treatment is optimized when the clinician instead performs a thorough assessment of sexual functioning before and during drug therapy using a standardized questionnaire such as the Arizona Sexual Experiences Scale (ASEX). Separating the effects of the disorder from those of medications is challenging; we present a concise, evidence-based schematic to assist physicians in minimizing treatment-emergent sexual dysfunction (TESD) while treating depression. Vascular, hormonal, neurogenic, and pharmacological factors should be considered when a patient presents with SD. We also recommend that physicians obtain patient information about baseline and historical sexual functioning before prescribing a drug that may lead to SD and follow up accordingly. When the goal is to treat depression while attenuating the risk of sexual symptoms, physicians may wish to consider agomelatine, bupropion, desvenlafaxine, moclobemide, trazodone, vilazodone, and vortioxetine.

scholarly journals Outcome measures for assessing change over time in studies of symptomatic children with hypermobility: a systematic review

2020 ◽  
Author(s):  
Muhammad Maarj ◽  
Andrea Coda ◽  
Louise Tofts ◽  
Cylie Williams ◽  
Derek Santos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Outcome Measures ◽  
Joint Hypermobility ◽  
Assessment Tools ◽  
Post Intervention ◽  
Associated Symptoms ◽  
Prospective Longitudinal

Abstract Background This study aimed to synthesise outcome measure type and use in interventional or prospective longitudinal studies of children with generalised joint hypermobility (GJH) and associated symptoms. Method Electronic searches of Medline, CINAHL and Embase databases from inception to 16th March 2020 were performed for studies of children with GJH and symptoms between 5-18 years reporting repeated outcome measures collected at least 4 weeks apart. Methodological quality of eligible studies were described using the Downs and Black checklist.Results Six studies comprising of five interventional, and one prospective observational study (total of 388 children) met the inclusion criteria. Interventional study durations were between 2 to 3 months, with up to 10 months post-intervention follow-up, while the observational study spanned 3 years. Three main constructs of pain, function and quality of life were reported as primary outcome measures using 20 different instruments. All but one measure was validated in paediatric populations, but not specifically for children with GJH and symptoms. One study assessed fatigue, reporting disabling fatigue to be associated with higher pain intensity. Conclusions There were no agreed sets of outcome measures for children with GJH and symptoms found. The standardisation of assessment tools across paediatric clinical trials is needed. Four constructs of pain, function, quality of life and fatigue are recommended to be included with agreed upon, validated, objective tools

scholarly journals Quality of life in acne vulgaris: Relationship to clinical severity and demographic data

2016 ◽  
Vol 82 (3) ◽  
pp. 292 ◽  
Author(s):  
Aayush Gupta ◽  
YugalKishor Sharma ◽  
KedarNath Dash ◽  
NitinDinkar Chaudhari ◽  
Sumit Jethani
Keyword(s):  
Quality Of Life ◽  
Acne Vulgaris ◽  
Demographic Data ◽  
Clinical Severity

VARIOUS DIAGNOSTIC MEASURES OF FRAILTY AS PREDICTORS FOR FALLS, WEIGHT CHANGE, QUALITY OF LIFE, AND MORTALITY AMONG OLDER FINNISH MEN

2017 ◽  
pp. 1-6
Author(s):  
N.M. Perttila ◽  
K.H. Pitkala ◽  
H. Kautiainen ◽  
R. Tilvis ◽  
T. Strandberg
Keyword(s):  
Quality Of Life ◽  
Observational Study ◽  
Weight Change ◽  
Frailty Index ◽  
Postal Questionnaire ◽  
Study Cohort ◽  
Diagnostic Measures ◽  
Lower Hrqol

Background: Frailty predisposes individuals to a variety of complications. However, there is no consensus on the definition of frailty. Objectives: To examine whether various frailty measures are equivalent in identifying the same individuals as being frail and whether the measures also predict similar outcomes. Design, Setting and Participants: The Helsinki Businessmen Study cohort, which is a long-term observational study of men born in 1919-1934, was used as the population. We investigated these men by their postal questionnaire responses in 2000 and 2005. The mean age of the men (N=480) was 73 years at the start of follow-up. Measurements: We compared two phenotypic frailty measures, the Helsinki Businessmen Study measure (HBS), the modified Women’s Health Initiative Observational Study (WHI-OS), and the Frailty Index (FI) comprising 20 items. All three measurements were applied to Helsinki Businessmen Study cohort data collected via simple postal questionnaire from 480 men. We investigated how effectively these three measures distinguished between the not frail, prefrail, and frail individuals, and predicted mortality, falls, weight change, and health-related quality of life (HRQoL, 15D instrument) during a 5-year follow-up. Results: The HBS and the modified WHI-OS identified 35 persons (7.3%) each as frail but their respective sets comprised different groupings of individuals that partly overlapped. The FI identified 86 persons (17.9%) as frail. One-hundred-and-two (21.3%) men were classified as frail by at least one of the measures. All three measures significantly predicted higher mortality, higher number of fallers, and lower HRQoL for frail participants. None of the measures showed different results for weight change between the frailty groups or frailty stages. Conclusions: All three measures identified somewhat different sets of participants as frail. They all predicted increased mortality, falls and reduced HRQoL for the frail groups.

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