Targeting the individual cancer patient

2011 ◽  
pp. 8-28 ◽  
Author(s):  
Georgios Baltogiannis ◽  
Christos S Katsios ◽  
Dimitrios H Roukos
Keyword(s):  
Cancer Patient ◽  
The Individual

scholarly journals Cancer in the Time of Coronavirus: A Call for Crisis Oncology Standards of Care

Healthcare ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 214
Author(s):  
Amar H. Kelkar ◽  
Christopher R. Cogle
Keyword(s):  
Supply Chain ◽  
Cancer Patient ◽  
Standards Of Care ◽  
Supply Chain Disruptions ◽  
Cancer Centers ◽  
Scarce Resources ◽  
Patients With Cancer ◽  
Global Pandemic ◽  
The Individual ◽  
Scarcity Of Resources

Since the Coronavirus Disease 2019 (COVID-19) was identified as a global pandemic, health systems have been severely strained, particularly affecting vulnerable populations such as patients with cancer. In response to the COVID-19 pandemic, a variety of oncology specialty societies are making recommendations for standards of care. These diverse standards and gaps in standards can lead to inconsistent and heterogeneous care among governments, cancer centers, and even among oncologists within the same practice. These challenges highlight the need for a common nomenclature and crisis guidelines. For times of increased scarcity of resources, the National Academy of Medicine developed Crisis Standards of Care, defined as fairness, duty to care, duty to steward resources, transparency, consistency, proportionality, and accountability. However, we believe there is an urgent need to develop cancer-specific guidelines by convening a panel of experts from multiple specialties. These would be Crisis Oncology Standards of Care (COSCs) that are sensitive to both the individual cancer patient and to the broader health system in times of scarce resources, such as pandemic, natural disaster, or supply chain disruptions.

scholarly journals Management of Cancer-Associated Thrombosis: An Evolving Area

Cancers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2999
Author(s):  
Corinne Frere ◽  
Jean M. Connors ◽  
Dominique Farge
Keyword(s):  
Cancer Patient ◽  
Clinical Decision Making ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Clinical Decision ◽  
Patient Centered ◽  
Patient Values ◽  
The Individual ◽  
The Right ◽  
Cancer Associated Thrombosis

The management of cancer-associated thrombosis (CAT) is an evolving area. With the use of direct oral anticoagulants as a new option in the management of CAT, clinicians now face several choices for the individual cancer patient with venous thromboembolism. A personalized approach, matching the right drug to the right patient, based on drug properties, efficacy and safety, side effect profile of each drug, and patient values and preference, will probably supplant the one size fits all approach of use of only low-molecular-weight heparin in the near future. We herein present eight translational, clinical research, and review articles on recent advances in the management of CAT published in the Special Issue “Treatment for Cancer-Associated Thrombosis” of Cancers. For now, a multidisciplinary patient-centered approach involving a close cooperation between oncologists and other specialists is warranted to guide clinical decision making and optimize the treatment of VTE in cancer patient.

Private Experience and Public Expectation on the Cancer Ward

1976 ◽  
Vol 6 (4) ◽  
pp. 373-381 ◽  
Author(s):  
Lea Baider
Keyword(s):  
Cancer Patient ◽  
Ethnic Differences ◽  
Pain Behavior ◽  
Anglo Saxon ◽  
Public Expectation ◽  
Impending Death ◽  
The Individual ◽  
Short Time

A sociologist relates her experiences with staff and patients on a cancer ward. Within a short time the staff perceived her as a threat to their system of efficiency-oriented norms and regulations, a system which she, in turn, came to regard as an institutionalized defense against that-which-could-not-be-confronted. In becoming acquainted with the patients themselves, the phenomenon of pain was brought to the fore. The patient's existence sometimes was dominated by pain, and yet there were significant differences from one cancer patient to another in how they interpreted and related to pain. These variations included positive valuation of pain as a symbol of life. Ethnic differences in the interpretation of pain, especially between people from Latin and Anglo-Saxon backgrounds, were observed. In general, pain behavior in terminal patients was strongly colored by the individual's feelings concerning impending death. The observer also shares some of her personal feelings of the rhythms of hospital life and their impact upon the individual.

Multilevel Influences on Black Cancer Patient Experiences With Care: A Qualitative Analysis

2021 ◽  
Vol 17 (5) ◽  
pp. e645-e653 ◽  
Author(s):  
Carol Y. Ochoa ◽  
Gabriela Toledo ◽  
Aisa Iyawe-Parsons ◽  
Stephanie Navarro ◽  
Albert J. Farias
Keyword(s):  
Health Care ◽  
Grounded Theory ◽  
Cancer Patient ◽  
Cancer Survivors ◽  
Patient Experiences ◽  
Theory Approach ◽  
Health Care Administrators ◽  
Personal Doctor ◽  
Global Ratings ◽  
The Individual

PURPOSE: Black patients with cancer report worse experiences with health care compared with White patients; however, little is known about what influences these ratings. The objective of this study is to explore the multilevel factors that influence global ratings of care for Black cancer survivors. METHODS: We conducted semistructured in-depth interviews with 18 Black cancer survivors. We assessed the global ratings of their personal doctor, specialist, health plan, prescription drug plan, and overall health care, and asked patients to elaborate on their rating. We analyzed the interviews with a deductive grounded theory approach using the socioecologic model to identify the individual, interpersonal, organizational, and environmental influences on Black cancer patient experiences with global ratings of care. We used an inductive constant comparison approach to identify additional themes that emerged. Two coauthors separately coded a set of transcripts and met to refine the codebook. RESULTS: On average, participants reported the highest mean rating for their specialist (9.39/10) and the lowest mean rating for their personal doctor (7.33/10). Emerging themes that influenced patient ratings were perceptions about their interaction with medical providers, physician communication, the doctor's expertise, and aspects of the physical facilities. Global ratings of care measures were widely influenced by patient interactions with their providers that were empathetic, nondiscriminatory, and where the doctors addressed all concerns. CONCLUSION: This grounded theory study identifies multiple aspects of health care that intervention researchers, health care administrators, and providers may target to improve Black cancer patient experiences with care.

Clinical Trial Results Applied to Management of the Individual Cancer Patient

2006 ◽  
Vol 30 (7) ◽  
pp. 1184-1189 ◽  
Author(s):  
Ismail Jatoi ◽  
Michael A. Proschan
Keyword(s):  
Clinical Trial ◽  
Cancer Patient ◽  
Clinical Trial Results ◽  
The Individual

scholarly journals Music Therapy on Cancer Patient: A Case Study

2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Dr Pubalin Dash
Keyword(s):  
Cancer Patient ◽  
Music Therapy ◽  
Empirical Studies ◽  
Medical Science ◽  
Depression Scale ◽  
Severe Depression ◽  
Physical Symptoms ◽  
Emotional States ◽  
Practice Problem ◽  
The Individual

The present investigation evaluated the utility of music therapy on cancer patient who met diagnostic criteria of medical science. Music therapy, as an adjunct to traditional therapies and treatment for those with mental health needs, has been demonstrated to be an effective intervention. It can allow individuals to explore personal feelings, to make positive changes in mood and emotional states, to practice problem solving, and to develop the skills required for wellbeing. Empirical studies of the use of music with oncology patients have demonstrated that music can reduce anxiety, stress and physical symptoms, can help to manage pain, can encourage a reflective awareness of emotion, and can enhance communication and quality of life. The participant of the present study is a forty years old professional detected blood cancer in 2013 having severe depression. The intervention was to use standard procedures of music therapy in order to design interventions that would be effective in reducing depression and stress of the individual. The treatment consisted of 10 sessions. The treatment was evaluated qualitatively by means of interviews with the participant and his family and quantitatively by means of repeated applications of depression scale. The results showed a decrease in the client’s depression, stress and an increase in pro social behavior. The client ultimately ceased from maximum depressive behavior and this outcome was sustained during his last two months in therapy.

Assessing the effect of toxicity on prognosis: methods of analysis and interpretation.

1988 ◽  
Vol 6 (5) ◽  
pp. 868-870 ◽  
Author(s):  
K J Propert ◽  
J R Anderson
Keyword(s):  
Clinical Trials ◽  
Treatment Outcome ◽  
Cancer Patient ◽  
Time Dependence ◽  
Statistical Analyses ◽  
Cytotoxic Agents ◽  
Cancer Clinical Trials ◽  
Time To Failure ◽  
Statistical Methodology ◽  
The Individual

There has recently been an increased interest in and reporting of the association between toxicity and treatment outcome in cancer clinical trials. Such comparisons may be used to suggest mechanisms by which cytotoxic agents function in the cancer patient, especially regarding the importance of the effect of dose on the individual patient. However, analyses of "time-to-failure" outcomes such as survival by toxicity are subject to bias due to the time-dependence of both the predictor and outcome variables. In addition, interpretation of even appropriately conducted statistical analyses is problematic, as with analyses of survival by outcome variables such as response. The use of statistical methodology designed to avoid such biases in these comparisons is shown and the problems in the interpretation of results are discussed.

Tailoring adjuvant treatments for the individual breast cancer patient

The Breast ◽  
2003 ◽  
Vol 12 (6) ◽  
pp. 558-568 ◽  
Author(s):  
R.D Gelber ◽  
M Bonetti ◽  
M Castiglione-Gertsch ◽  
A.S Coates ◽  
A Goldhirsch
Keyword(s):  
Breast Cancer ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
The Individual

Comment: predictability of survival in the individual patient with lung cancer

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1036-1037 ◽  
Author(s):  
P. Rubin
Keyword(s):  
Lung Cancer ◽  
The Individual

The Ultrastructure of Monkey Gingival Epithelium

1967 ◽  
Vol 25 ◽  
pp. 16-17
Author(s):  
C.N. Sun
Keyword(s):  
Epithelial Cells ◽  
Macaca Nemestrina ◽  
Stratum Granulosum ◽  
Solution Ph ◽  
Gingival Epithelial Cells ◽  
Stratum Spinosum ◽  
Cell Layers ◽  
Gingival Epithelium ◽  
The Individual ◽  
Different Thickness

The present study demonstrates the ultrastructure of the gingival epithelium of the pig tail monkey (Macaca nemestrina). Specimens were taken from lingual and facial gingival surfaces and fixed in Dalton's chrome osmium solution (pH 7.6) for 1 hr, dehydrated, and then embedded in Epon 812.Tonofibrils are variable in number and structure according to the different region or location of the gingival epithelial cells, the main orientation of which is parallel to the long axis of the cells. The cytoplasm of the basal epithelial cells contains a great number of tonofilaments and numerous mitochondria. The basement membrane is 300 to 400 A thick. In the cells of stratum spinosum, the tonofibrils are densely packed and increased in number (fig. 1 and 3). They seem to take on a somewhat concentric arrangement around the nucleus. The filaments may occur scattered as thin fibrils in the cytoplasm or they may be arranged in bundles of different thickness. The filaments have a diameter about 50 A. In the stratum granulosum, the cells gradually become flatted, the tonofibrils are usually thin, and the individual tonofilaments are clearly distinguishable (fig. 2). The mitochondria and endoplasmic reticulum are seldom seen in these superficial cell layers.

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