Investigation of dual plasmonic core-shell Ag@CuS nanoparticles for potential surface-enhanced Raman spectroscopy-guided photothermal therapy

Nanomedicine ◽  
2021 ◽  
Author(s):  
Anindita Das ◽  
Vinothini Arunagiri ◽  
Hsieh-Chih Tsai ◽  
Adhimoorthy Prasannan ◽  
Juin-Yih Lai ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Photothermal Therapy ◽  
Heat Dissipation ◽  
Near Infrared ◽  
Surface Enhanced Raman Spectroscopy ◽  
Infrared Light ◽  
Core Shell ◽  
Theoretical Simulation ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Aim: To prepare efficient metal-semiconductor nanoparticles as noninvasive, real-time imaging probes for photothermal therapy (PTT) applications. Materials & methods: A bottom-up approach was used to fabricate core-shell Ag@CuS nanoparticles (NPs). PTT and Raman mapping were done using HeLa cells. Theoretical simulation of electric field enhancement and heat dissipation density of Ag@CuS NPs was performed. Results: PTT-induced hyperthermia was achieved under 940 nm near-infrared light irradiation. Surface-enhanced Raman spectroscopy (SERS) signals of dye molecules were observed when conjugated with Ag@CuS NPs. Conclusion: Ag@CuS NPs are found to be efficient for SERS imaging and localized heating under laser irradiation, making a promising candidate for SERS-guided PTT.

scholarly journals Bimetallic Core–Shell Nanoparticles of Gold and Silver via Bioinspired Polydopamine Layer as Surface-Enhanced Raman Spectroscopy (SERS) Platform

Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 688 ◽  
Author(s):  
Asli Yilmaz ◽  
Mehmet Yilmaz
Keyword(s):  
Raman Spectroscopy ◽  
Low Cost ◽  
Silver Ions ◽  
Surface Enhanced Raman Spectroscopy ◽  
Core Shell ◽  
Silver Deposition ◽  
Shell Nanoparticles ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Core Shell Nanoparticles

Despite numerous attempts to fabricate the core–shell nanoparticles, novel, simple, and low-cost approaches are still required to produce these efficient nanosystems. In this study, we propose the synthesis of bimetallic core–shell nanoparticles of gold (AuNP) and silver (AgNP) nanostructures via a bioinspired polydopamine (PDOP) layer and their employment as a surface-enhanced Raman spectroscopy (SERS) platform. Herein, the PDOP layer was used as an interface between nanostructures as well as stabilizing and reducing agents for the deposition of silver ions onto the AuNPs. UV-vis absorption spectra and electron microscope images confirmed the deposition of the silver ions and the formation of core–shell nanoparticles. SERS activity tests indicated that both the PDOP thickness and silver deposition time are the dominant parameters that determine the SERS performances of the proposed core–shell system. In comparison to bare AuNPs, more than three times higher SERS signal intensity was obtained with an enhancement factor of 3.5 × 105.

Study on Cervical Cancer Oxyhemoglobin Using Near-Infrared Surface-Enhanced Raman Spectroscopy

2015 ◽  
Vol 42 (1) ◽  
pp. 0115001 ◽  
Author(s):  
熊洋 Xiong Yang ◽  
司民真 Si Minzhen ◽  
高飞 Gao Fei ◽  
张德清 Zhang Deqing
Keyword(s):  
Cervical Cancer ◽  
Raman Spectroscopy ◽  
Near Infrared ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman
Sign in / Sign up

Export Citation Format

Share Document