scholarly journals The management of risk and investment in cell therapy process development: a case study for neurodegenerative disease

2019 ◽  
Vol 14 (5) ◽  
pp. 465-488 ◽  
Author(s):  
Sujith Sebastian ◽  
Paul Hourd ◽  
Amit Chandra ◽  
David J Williams ◽  
Nicholas Medcalf
Keyword(s):  
Cell Therapy ◽  
Neurodegenerative Disease ◽  
Process Development ◽  
Therapy Process ◽  
Management Of Risk

Developing assays to address identity, potency, purity and safety: cell characterization in cell therapy process development

2012 ◽  
Vol 7 (1) ◽  
pp. 85-100 ◽  
Author(s):  
Jessica Carmen ◽  
Scott R Burger ◽  
Michael McCaman ◽  
Jon A Rowley
Keyword(s):  
Cell Therapy ◽  
Process Development ◽  
Therapy Process ◽  
Cell Characterization

Government Policies and Rural Entrepreneurship- Case Study of an Horticulture Entrepreneur

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Vinod N. Sambrani
Keyword(s):  
Rural Development ◽  
Rural Areas ◽  
Process Development ◽  
Full Time ◽  
Rural Entrepreneurship ◽  
Development Institutions ◽  
Startup Time ◽  
Nursery Management ◽  
The Government

India is a country which is in forefront of being called a developed nation. To be a developed nation, India has to first look at its rural development, because 70 percent of the population live in rural areas, which means more than 700 million people are spread across 6,27,000 villages. Rural development is more than ever before linked to entrepreneurship. Establishments and agencies promoting rural development now look at entrepreneurship as a strategic development medium that could speed up the rural development process. Development institutions believe that rural entrepreneurship offers a huge potential for employment. In this paper a case study of a young entrepreneur who has taken up horticulture (vegetable plants nursery) as his full time profession, with a mission to help the neighbouring farmers is studied, the purpose of this paper is to understand the government role (policies and schemes), the difficulties faced by the entrepreneur during the startup time and knowledge transfer from the horticulture department, nursery management. The methodology followed is in-depth interaction with the entrepreneur. The outcome of paper will be to understand how rural entrepreneurship is helping improve the quality of life for families, communities and individuals leading to sustainable economy and environment.

Chemical engineering methodology in process development: A case study of MenD-catalyzed 1,4-addition of α-ketoglutaric acid to acrylonitrile

2018 ◽  
Vol 44 ◽  
pp. S132-S133
Author(s):  
Z. Findrik Blaževic ◽  
M. Sudar ◽  
I. Dejanovic ◽  
M. Müller ◽  
Ð. Vasic-Racki
Keyword(s):  
Chemical Engineering ◽  
Process Development

Productivity improvement in heart surgery – a case study on care process development

2004 ◽  
Vol 15 (3) ◽  
pp. 238-246 ◽  
Author(s):  
Sauli Karvonen ◽  
Juhani Rämö ◽  
Mauri Leijala ◽  
Jan Holmström
Keyword(s):  
Heart Surgery ◽  
Process Development ◽  
Care Process ◽  
Productivity Improvement

LCA in Process Development: Case Study of the OxFA-Process

2018 ◽  
pp. 105-113
Author(s):  
Simon Rauch ◽  
Frank Piepenbreier ◽  
Dorothea Voss ◽  
Jakob Albert ◽  
Martin Hartmann
Keyword(s):  
Process Development

Wedge Bond Process Optimization Method for 1.5 mil Al Wire on Al Bond Pad

2015 ◽  
Vol 2015 (1) ◽  
pp. 000413-000418
Author(s):  
Wenjuan Qi ◽  
Daniel D. Evans
Keyword(s):  
Process Development ◽  
Optimization Method ◽  
Black Ring ◽  
Basic Relationship ◽  
Force Time ◽  
Bond Pads ◽  
Wedge Bonding ◽  
The Relationship ◽  
Inputs And Outputs

Modern wedge bonders have evolved since their early inception in 1957. This paper will review the common challenges process engineers face when selecting a wedge bond machine configuration and developing robust processes. Wedge bond cases presented will show the tradeoff between process inputs and the resulting bond shapes, bond appearance of black ring, burrs, pull results, etc. The purpose of this work was to optimize the process outputs: bond shape, black ring, burrs, and pulls on a die with aluminum bond pads. Process inputs included Force, Time, and Ultrasonic Level. An aluminum wafer was used to understand the basic relationship between process parameter inputs and outputs. The learning was then applied to a die with aluminum bond pads. Examples of non-compliance and compliance will be shown to help process engineers evaluate wedge bonds and make refinements. The case studied was for an aluminum bond pad/Al wafer and 1.5 mil aluminum wire interaction that creates burrs around the bond (wire to pad interface), black ring on the bond periphery (wedge tool to wire interface) and the resulting pulls. Both the graphical and numerical results of the case study have clearly demonstrated the relationship between the typical process inputs and outputs, particularly bond shape, burrs, black ring and pulls. The findings in this study will provide a general guideline and a troubleshooting reference for wedge bonding process development.

Pembentukan Sistem Pembangunan Proses (Process Development System) Melalui Proses Penambahbaikan di Kilang Lampin Pakai Buang

2012 ◽  
Author(s):  
Mohamad Nasir Saludin ◽  
Mohamad Nizam Abu Talib
Keyword(s):  
Process Improvement ◽  
Preventive Maintenance ◽  
Process Development ◽  
Video Recording ◽  
Time Machine ◽  
Statistical Process ◽  
Development System ◽  
Production Processes ◽  
Maintenance Time

SSistem Pembangunan Proses (Process Development System) merupakan satu pendekatan kejuruteraan sistematik terkini untuk menganalisis masalah dan menambahbaik kualiti produk atau proses. Kajian ini hanya memfokuskan kepada masalah proses pengeluaran dan penambahbaikan ke atas proses pengeluaran lampin pakai buang (diaper). Kajian ini dilakukan ke atas salah satu mesin (Mesin Technipro) pembuat lampin pakai buang. Kombinasi kawalan proses statistik dan pendekatan lain seperti Kepner Tregoe, Poka Yoke, SMED, zero setting, centerlining, F1 Pit Shop dan rakaman video digunakan untuk melakukan penambahbaikan. Ukuran masa perjalanan mesin, masa mesin berhenti akibat mengalami kerosakan, masa penyelenggaraan mesin, peratus kecekapan mesin, peratus produk yang dihasilkan dalam sejam, peratus masa lengah mesin dan peratus kecacatan yang terhasil digunakan bagi membandingkan hasil dari proses penambahbaikan yang dijalankan. Kajian ini telah berjaya membangunkan dan mereka bentuk sistem pembangunan proses bagi memperbaiki proses-proses yang sedia ada. Kata kunci: Sistem Pembangunan Proses, proses penambahbaikan, lampin pakai buang Process Development System is a systematic engineering approach to analyze problems and improve the processes and product quality. This study focuses on the problem of diaper production processes and its improvements. For the case study, one dedicated machine (Technopro Machine) is selected. Combination of Statistical Process Control and other approaches like Kepner Tregoe concept, Poka Yoke concept, SMED concept, zero setting, centerlining, F1 Pit Stop concept, and video recording are used in the improvement process. The machine running time, machine downtime, preventive maintenance time, machine efficiency percentage, and product produced per hour are used to monitor the efficiency of the improved processes. This study is successful in developing and designing the Process Development System to improve the existing processes. Keywords: Process Development System, process improvement, diaper

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