Systematic Review of the Literature on Machine Learning Techniques Employed in Real-World Data Analysis for Patient-Provider Decision Making

Author(s):  
Kushagra Singh Sisodiya

Abstract: The Industrial Revolution 4.0 has flooded the virtual world with data, which includes Internet of Things (IoT) data, mobile data, cybersecurity data, business data, social networks, including health data. To analyse this data efficiently and create related efficient and streamlined applications, expertise in artificial intelligence specifically machine learning (ML), is required. This field makes use of a variety of machine learning methods, including supervised, unsupervised, semi-supervised, and reinforcement. Additionally, deep learning, which is a subset of a larger range of machine learning techniques, is capable of effectively analysing vast amounts of data. Machine learning is a broad term that encompasses a number of methods used to extract information from data. These methods may allow the rapid translation of massive real-world information into applications that assist patients and providers in making decisions. The objective of this literature review was to find observational studies that utilised machine learning to enhance patient-provider decision-making utilising secondary data. Keywords: Machine Learning, Real World, Patient, Population, Artificial Intelligence

Author(s):  
Yining Xu ◽  
Xinran Cui ◽  
Yadong Wang

Tumor metastasis is the major cause of mortality from cancer. From this perspective, detecting cancer gene expression and transcriptome changes is important for exploring tumor metastasis molecular mechanisms and cellular events. Precisely estimating a patient’s cancer state and prognosis is the key challenge to develop a patient’s therapeutic schedule. In the recent years, a variety of machine learning techniques widely contributed to analyzing real-world gene expression data and predicting tumor outcomes. In this area, data mining and machine learning techniques have widely contributed to gene expression data analysis by supplying computational models to support decision-making on real-world data. Nevertheless, limitation of real-world data extremely restricted model predictive performance, and the complexity of data makes it difficult to extract vital features. Besides these, the efficacy of standard machine learning pipelines is far from being satisfactory despite the fact that diverse feature selection strategy had been applied. To address these problems, we developed directed relation-graph convolutional network to provide an advanced feature extraction strategy. We first constructed gene regulation network and extracted gene expression features based on relational graph convolutional network method. The high-dimensional features of each sample were regarded as an image pixel, and convolutional neural network was implemented to predict the risk of metastasis for each patient. Ten cross-validations on 1,779 cases from The Cancer Genome Atlas show that our model’s performance (area under the curve, AUC = 0.837; area under precision recall curve, AUPRC = 0.717) outstands that of an existing network-based method (AUC = 0.707, AUPRC = 0.555).


Philosophies ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 27
Author(s):  
Jean-Louis Dessalles

Deep learning and other similar machine learning techniques have a huge advantage over other AI methods: they do function when applied to real-world data, ideally from scratch, without human intervention. However, they have several shortcomings that mere quantitative progress is unlikely to overcome. The paper analyses these shortcomings as resulting from the type of compression achieved by these techniques, which is limited to statistical compression. Two directions for qualitative improvement, inspired by comparison with cognitive processes, are proposed here, in the form of two mechanisms: complexity drop and contrast. These mechanisms are supposed to operate dynamically and not through pre-processing as in neural networks. Their introduction may bring the functioning of AI away from mere reflex and closer to reflection.


Author(s):  
Bruce Mellado ◽  
Jianhong Wu ◽  
Jude Dzevela Kong ◽  
Nicola Luigi Bragazzi ◽  
Ali Asgary ◽  
...  

COVID-19 is imposing massive health, social and economic costs. While many developed countries have started vaccinating, most African nations are waiting for vaccine stocks to be allocated and are using clinical public health (CPH) strategies to control the pandemic. The emergence of variants of concern (VOC), unequal access to the vaccine supply and locally specific logistical and vaccine delivery parameters, add complexity to national CPH strategies and amplify the urgent need for effective CPH policies. Big data and artificial intelligence machine learning techniques and collaborations can be instrumental in an accurate, timely, locally nuanced analysis of multiple data sources to inform CPH decision-making, vaccination strategies and their staged roll-out. The Africa-Canada Artificial Intelligence and Data Innovation Consortium (ACADIC) has been established to develop and employ machine learning techniques to design CPH strategies in Africa, which requires ongoing collaboration, testing and development to maximize the equity and effectiveness of COVID-19-related CPH interventions.


Author(s):  
Gediminas Adomavicius ◽  
Yaqiong Wang

Numerical predictive modeling is widely used in different application domains. Although many modeling techniques have been proposed, and a number of different aggregate accuracy metrics exist for evaluating the overall performance of predictive models, other important aspects, such as the reliability (or confidence and uncertainty) of individual predictions, have been underexplored. We propose to use estimated absolute prediction error as the indicator of individual prediction reliability, which has the benefits of being intuitive and providing highly interpretable information to decision makers, as well as allowing for more precise evaluation of reliability estimation quality. As importantly, the proposed reliability indicator allows the reframing of reliability estimation itself as a canonical numeric prediction problem, which makes the proposed approach general-purpose (i.e., it can work in conjunction with any outcome prediction model), alleviates the need for distributional assumptions, and enables the use of advanced, state-of-the-art machine learning techniques to learn individual prediction reliability patterns directly from data. Extensive experimental results on multiple real-world data sets show that the proposed machine learning-based approach can significantly improve individual prediction reliability estimation as compared with a number of baselines from prior work, especially in more complex predictive scenarios.


2018 ◽  
Vol 31 (3) ◽  
pp. 429-435 ◽  
Author(s):  
Kathryn Rendell ◽  
Irena Koprinska ◽  
Andre Kyme ◽  
Anja A Ebker‐White ◽  
Michael M Dinh

2016 ◽  
Author(s):  
Ευτύχιος Πρωτοπαπαδάκης

Ο όρος μάθηση με μερική επίβλεψη αναφέρεται σε ένα ευρύ πεδίο τεχνικών μηχανικής μάθησης, οι οποίες χρησιμοποιούν τα μη τιτλοφορημένα δεδομένα για να εξάγουν επιπλέον ωφέλιμη πληροφορία. Η μερική επίβλεψη αντιμετωπίζει προβλήματα που σχετίζονται με την επεξεργασία και την αξιοποίηση μεγάλου όγκου δεδομένων και τα όποια κόστη σχετίζονται με αυτά (π.χ. χρόνος επεξεργασίας, ανθρώπινα λάθη). Απώτερος σκοπός είναι η ασφαλή εξαγωγή συμπερασμάτων, κανόνων ή προτάσεων. Τα μοντέλα λήψης απόφασης που χρησιμοποιούν τεχνικές μερικής μάθησης έχουν ποικίλα πλεονεκτήματα. Σε πρώτη φάση, χρειάζονται μικρό πλήθος τιτλοφορημένων δεδομένων για την αρχικοποίηση τους. Στη συνέχεια, τα νέα δεδομένα που θα εμφανιστούν αξιοποιούνται και τροποποιούν κατάλληλα το μοντέλο. Ως εκ τούτου, έχουμε ένα συνεχώς εξελισσόμενο μοντέλο λήψης αποφάσεων, με την ελάχιστη δυνατή προσπάθεια.Τεχνικές που προσαρμόζονται εύκολα και οικονομικά είναι οι κατεξοχήν κατάλληλες για τον έλεγχο συστημάτων, στα οποία παρατηρούνται συχνές αλλαγές στον τρόπο λειτουργίας. Ενδεικτικά πεδία εφαρμογής εφαρμογής ευέλικτων συστημάτων υποστήριξης λήψης αποφάσεων με μερική μάθηση είναι: η επίβλεψη γραμμών παραγωγής, η επιτήρηση θαλάσσιων συνόρων, η φροντίδα ηλικιωμένων, η εκτίμηση χρηματοπιστωτικού κινδύνου, ο έλεγχος για δομικές ατέλειες και η διαφύλαξη της πολιτιστικής κληρονομιάς.


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