scholarly journals Comparative Study of Various Pharmacological Screening of Argyreia Speciosa Sweet. In Relation with Ayurvedic Documented Literature

1970 ◽  
Vol 7 (5) ◽  
pp. 37-41
Author(s):  
K P Unadkat ◽  
D K Jani ◽  
R C Pandey
Keyword(s):  
Wound Healing ◽  
Comparative Study ◽  
Traditional Healers ◽  
Health It ◽  
Anti Cancer ◽  
Argyreia Nervosa ◽  
Pharmacological Screening ◽  
Anti Fungal ◽  
Pharmacological Testing ◽  
Wound Healing Activity

Vruddhadaru is one of the important herbs in Ayurveda. It has been used in Ayurvedic traditional literature for various diseases and improves the health. It is also used as folklore medicine. Out of its entire therapeutic spectrum, the herb is famous for its wound healing activity for longer time. The Latin name of Vruddhadaru is Argyreia speciosa(Syn.-Argyreia nervosa; Family-Convolvulaceae).Argyreia speciosa is commonly known as Vruddhadaru in Sanskrit, Vidhara in Hindi, Elephant creeper in English and Samudrashosha in Gujarati. It has many synonyms like Aavegi, Chhagalantri, Vrushyagandhika etc.  It has been described in Dhanvantari Nighantu, Madanpala Nighantu, Kaiyadeva Nighantu, Raj Nighantu, Bhavaprakasha Nighantu, Nighantu Adarsh etc. This shows the importance of the drug. It is usually appreciated for its aesthetic merit. Therapeutically proven activities of this plant are – analgesic & anti-inflammatory, anti-cancer, anti-convulsant, anti-diarrheal, anti-fungal, anti-microbial, anti-obesity, antipyretic, anti-stress, anti-ulcer, anti-viral, aphrodisiac, CNS effect, hepatoprotective, hypoglycaemic, immunomodulatory, nootropic, wound healing activity etc. It is very interesting to observe that most of the pharmacological screened activities are documented in Ayurveda by various authors but in the language of Ayurveda. It shows that the former scientists (Ayurveda Philosophers) are extreme aware about the activity of the herb and was in practice as an Ayurveda medicine. The conventional evidences about the activity are the proof that there must be a scientific technique with the traditional healers to document the properties of the herb. The present review explains the correlation of the same activity noted by two different streams. This review helps to design futuristic pathway for pharmacological testing of herbs.     Keywords: Vruddhadaaru, Argyreia speciosa, pharmacological screening, Ayurveda

scholarly journals Comparative Study of Wound-Healing Activity of Dihydroquercetin Pseudopolymorphic Modifications

2021 ◽  
Author(s):  
R. P. Terekhov ◽  
I. A. Selivanova ◽  
M. N. Anurova ◽  
A. K. Zhevlakova ◽  
I. D. Nikitin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Comparative Study ◽  
Wound Healing Activity

A REVIEW OF PHYTOMORPHOLOGICAL, PHYTOCHEMICAL AND PHARMACOLOGICAL ACTIVITY ON IPOMOEA CARNEA

2021 ◽  
Vol 12 (4) ◽  
pp. 166-169
Author(s):  
Mahaveer Sing ◽  
Sravan P Kumar ◽  
Birendra Shrivastava ◽  
Pamula B Reddy ◽  
Suma Rohilla
Keyword(s):  
Wound Healing ◽  
Pharmacological Activity ◽  
Wild Plant ◽  
Toxicological Effects ◽  
Ipomoea Carnea ◽  
Anti Cancer ◽  
Anti Inflammatory ◽  
Anti Fungal

Ipomoea carnea Jacq. grows as wild plant in India. It is identified as a useful material for several applications including medicinal purposes. Different extracts of Ipomoea carnea plant possess anti-bacterial, anti-fungal, antioxidant, antimicrobial, anti-cancer, anti-convulsant, immune modulatory, antidiabetic, hepatoprotective, anti-inflammatory, anxiolytic, sedative, cardiovascular, inhibition and wound healing activities. However, some toxicological effects have been also reported. In this review the potential of phytochemical, pharmacological and other activities of Ipomoea carnea are discussed.

Comparative study of wound-healing activity of taxifolin pseudopolymorphic modifications

2020 ◽  
Vol 170 (10) ◽  
pp. 452-456
Author(s):  
R. P. Terekhov ◽  
◽  
I. A. Selivanova ◽  
M. N. Anurova ◽  
A. K. Zhevlakova ◽  
...  
Keyword(s):  
Wound Healing ◽  
Comparative Study ◽  
Wound Healing Activity

Preliminary Phytochemical Analysis and Wound Healing Activity from the Leaves of Cocculus hirsutus Diels

2009 ◽  
Vol 2 (3) ◽  
pp. 675-678 ◽  
Author(s):  
Panda Bikash Ranjan ◽  
Mohanta S.R ◽  
Sii S. ◽  
Das G. K.
Keyword(s):  
Wound Healing ◽  
Petroleum Ether ◽  
Methanol Extract ◽  
Traditional Healers ◽  
Phytochemical Analysis ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
Scientific Support ◽  
Cocculus Hirsutus ◽  
Wound Healing Activity

In qualitative phytochemical analysis of petroleum ether, chloroform and methanol extracts of the leaves of Cocculus hirsutus Diels, the important secondary plant metabolites detected are Carbohydrates, Steroids, Glycosides, Tannins, Saponins and Flavonoids. The methanol extract and fresh leaves juice are subjected to wound healing activity in incision and excision wound models taking Soframycin sulphate as standard. The results revealed that the methanol extract ointment 10%w/w has highest wound healing potency among the test groups and is comparable with the standard and thus the results offer a scientific support to the treatment of traditional healers of this region.

Design, Network Analysis and In Silico Modeling of Biologically Significant 4-(substituted benzyl)-2-Amino-6-HydroxyPyrimidine-5-Carboxamide Nanoparticles

Drug Research ◽  
2017 ◽  
Vol 67 (05) ◽  
pp. 289-301
Author(s):  
Theivendren Panneerselvam ◽  
Vellaichamy Sivakumar ◽  
Subramanian Arumugam ◽  
Kunjiappan Selvaraj ◽  
Murugan Indhumathy
Keyword(s):  
Wound Healing ◽  
Pain Management ◽  
Network Analysis ◽  
In Silico ◽  
Synthesis Of Nanoparticles ◽  
Wound Model ◽  
In Silico Modeling ◽  
Human Proteins ◽  
Pharmacological Screening ◽  
Wound Healing Activity

Abstract The synthesized 4-(4-hydroxy benzyl)-2-amino-6-hydroxy pyrimidine-5-carboxamide was chosen to perform in silico modeling with identified drug target AGT, TNF, F2 and BCL2L1. The identified human proteins are vital in the pain management and also an important target for the study of wound healing activity. The enzymes were identified by using BioGRID, string database and network analysis through Cytoscape software. The wound healing activity was evaluated by excision wound model. The observed results revealed that, the pyrimidine nanoparticles showed significant wound healing activity compared to standard and synthesized compound. The detailed synthesis of nanoparticles formulation spectral analysis and pharmacological screening data’s were reported. The revealed reports of synthesized analogues and formulated nanoparticles will generate a very good impact to the chemists and research scholars for further investigations in wound healing and pain management.

Testing Wound-healing Activity in T15 Fibroblast Cultures: A Morphometric Analysis

2000 ◽  
Vol 28 (1) ◽  
pp. 41-51 ◽  
Author(s):  
Seval Korkmaz ◽  
Hülya Zeytinoglu ◽  
Melih Zeytinoglu ◽  
Süleyman Aydin ◽  
Yusuf Öztürk ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cell Cultures ◽  
Centella Asiatica ◽  
Fibroblast Cell ◽  
Mechanisms Of Action ◽  
Cell Staining ◽  
Morphometric Analyses ◽  
Pharmacological Screening ◽  
Wound Healing Activity ◽  
Intracellular Collagen

The purpose was to evaluate the use of mouse T15 fibroblast cell cultures for the investigation of wound-healing activity. In order to investigate their mechanisms of action, the effects of drugs with wound-healing activities were compared by using morphometric analyses by microscopy after cell staining. A number of parameters were used to evaluate the effects of titrated extracts from Centella asiatica and dexpanthenol (drugs that have been used in medical practice for their wound-healing activities) on cultured mouse T15 fibroblasts. These parameters were: the total number of cells; the number of T15 cells in mitosis; the percentages of fusiform, polygonal, round and vacuole-containing cells; and the number of intracellular collagen granules. The results indicate that these two drugs exhibit wound-healing activities by activating fibroblast cells, and have cytoprotective effects, although their mechanisms of action on mouse T15 fibroblasts were different. On the basis of our findings, mouse T15 fibroblast cell cultures seem to be useful for the pharmacological screening of compounds with wound-healing activity.

Sign in / Sign up

Export Citation Format

Share Document