scholarly journals Comparative analysis of surgical interventions in the treatment of patients with metastatic lesions of the femur in combination with pathological fractures

2020 ◽  
Vol 24 (3) ◽  
pp. 237-244
Author(s):  
Jun Wang ◽  
N. V Kharchenko
Keyword(s):  
Comparative Analysis ◽  
Pathological Fracture ◽  
Metastatic Lesion ◽  
Pathological Fractures ◽  
Main Method ◽  
Surgical Interventions ◽  
Advantages And Disadvantages ◽  
Metastatic Lesions ◽  
Negative Effect

One of the most severe complications of metastatic lesion of the skeleton is the development of a pathological fracture, which not only affects the quality of life, makes it difficult to carry out adequate systemic treatment, but also has a negative effect on survival. In case of a pathological fracture, the main method of treatment is a surgical method. The main goal of the correction is to achieve stability and reduce metastatic pain in the area of damage or fracture. Today, the most popular organ-preserving operations for metastatic lesions of the femur in combination with pathological fractures are endoprosthesis and intramedullary osteosynthesis. In this paper, a comparative analysis of the results of their use is carried out, the advantages and disadvantages of each of the methods are described.

Contrast-Enhanced MRI with Magnetization Transfer Effect in the Imaging of Brain Metastatic Lesions

2017 ◽  
pp. 8-17
Author(s):  
A. A. Ermakova ◽  
O. Yu. Borodin ◽  
M. Yu. Sannikov ◽  
S. D. Koval ◽  
V. Yu. Usov
Keyword(s):  
Comparative Analysis ◽  
Roc Analysis ◽  
Magnetization Transfer ◽  
Metastatic Lesion ◽  
Transfer Effect ◽  
Wilcoxon Test ◽  
Post Contrast ◽  
Metastatic Lesions ◽  
The Brain ◽  
Non Parametric

Purpose: to investigate the diagnostic opportunities of contrast  magnetic resonance imaging with the effect of magnetization transfer effect in the diagnosis of focal metastatic lesions in the brain.Materials and methods.Images of contrast MRI of the brain of 16  patients (mean age 49 ± 18.5 years) were analysed. Diagnosis of  the direction is focal brain lesion. All MRI studies were carried out  using the Toshiba Titan Octave with magnetic field of 1.5 T. The  contrast agent is “Magnevist” at concentration of 0.2 ml/kg was  used. After contrasting process two T1-weighted studies were  performed: without T1-SE magnetization transfer with parameters of pulse: TR = 540 ms, TE = 12 ms, DFOV = 24 sm, MX = 320 × 224  and with magnetization transfer – T1-SE-MTC with parameters of pulse: ΔF = −210 Hz, FA(МТС) = 600°, TR = 700 ms, TE = 10 ms,  DFOV = 23.9 sm, MX = 320 x 224. For each detected metastatic  lesion, a contrast-to-brain ratio (CBR) was calculated. Comparative  analysis of CBR values was carried out using a non-parametric  Wilcoxon test at a significance level p < 0.05. To evaluate the  sensitivity and specificity of the techniques in the detection of  metastatic foci (T1-SE and T1-SE-MTC), ROC analysis was used. The sample is divided into groups: 1 group is foci ≤5 mm in size, 2  group is foci from 6 to 10 mm, and 3 group is foci >10 mm. Results.Comparative analysis of CBR using non-parametric Wilcoxon test showed that the values of the CBR on T1-weighted  images with magnetization transfer are significantly higher (p  <0.001) that on T1-weighted images without magnetization transfer. According to the results of the ROC analysis, sensitivity in detecting  metastases (n = 90) in the brain on T1-SE-MTC and T1-SE was  91.7% and 81.6%, specificity was 100% and 97.6%, respectively.  The accuracy of the T1-SE-MTC is 10% higher in comparison with  the technique without magnetization transfer. Significant differences (p < 0.01) between the size of the foci detected in post-contrast T1- weighted images with magnetization transfer and in post-contrast  T1-weighted images without magnetization transfer, in particular for  foci ≤5 mm in size, were found. Conclusions1. Comparative analysis of CBR showed significant (p < 0.001)  increase of contrast between metastatic lesion and white matter on  T1-SE-MTC in comparison with T1-SE.2. The sensitivity, specificity and accuracy of the magnetization transfer program (T1-SE-MTC) in detecting foci of  metastatic lesions in the brain is significantly higher (p < 0.01), relative to T1-SE.3. The T1-SE-MTC program allows detecting more foci in comparison with T1-SE, in particular foci of ≤5 mm (96% and 86%, respectively, with p < 0.05).

scholarly journals Java GUI application for comparing the levels of biometric security: Fingerprint vs. Iris

2021 ◽  
Vol 69 (3) ◽  
pp. 676-686
Author(s):  
Komlen Lalović ◽  
Mitko Bogdanoski
Keyword(s):  
Comparative Analysis ◽  
Iris Recognition ◽  
Scientific Data ◽  
Body Parts ◽  
Main Method ◽  
Software Application ◽  
Java Programming ◽  
Advantages And Disadvantages ◽  
Iris Biometrics ◽  
The Difference

Introduction/purpose: The main purpose of this paper is to present a novel Java GUI - based software application for a comparative analysis of fingerprint and iris biometrics. Methods: The first part of this work is realized in Java Programming language. in the GUI framework named swing while the rest of the paper shows in detail the advantages and disadvantages of both systems and gives scientific data on when fingerprint and iris recognition can be used to enable top level security. The main method here is a well known comparative analysis. Results: The results were obtained for both fingerprint and iris biometrics, showing the difference between the two. Conclusion: Different types of biometrics, based on body parts formed at different age, are given as well as the comparison of their security levels.

scholarly journals MULTILEVEL VERTEBROPLASTY WITH MULTIPLE METASTATIC LESIONS OF THE SPINE

2014 ◽  
Vol 5 (2) ◽  
pp. 47-53
Author(s):  
A V Bukharov ◽  
V Yu Karpenko ◽  
D S Agzamov ◽  
N A Rubtsova ◽  
V A Derzhavin
Keyword(s):  
Severe Pain ◽  
Pathological Fracture ◽  
Clinical Observation ◽  
Pathological Fractures ◽  
Metastatic Lesions ◽  
Vertebral Bodies ◽  
Short Time

Presented the clinical observation of patients with multiple metastatic and myeloma lesions of the spine with the presence of pathological fractures of vertebral bodies and severe pain. The authors recommend multilevel vertebroplasty, as it allows to reduce pain, to prevent pathological fracture of the spine, and activate patients in a short time.

scholarly journals NUCLEAR ZIRCONIUM – THE BASIS OF ALLOYS WITH IMPROVED NEUTRON-PHYSICAL, RADIATION, AND CORROSION PROPERTIES

2020 ◽  
pp. 97-102
Author(s):  
A.P. Mukhachev ◽  
M.M. Pylypenko ◽  
O.A. Kharуtonova
Keyword(s):  
Comparative Analysis ◽  
Corrosion Properties ◽  
Advantages And Disadvantages ◽  
Zirconium Tetrafluoride ◽  
Salt Recovery

The paper provides a review of industrial technologies for the production of nuclear zirconium. Their advantages and disadvantages have been shown, a comparative analysis of the quality of zirconium and hafnium salts has been given. Zirconium with a purity of 99.95%, is on a par with the quality of the iodide metal, with a hafnium content of less than 0.005%, was obtained from zirconium tetrafluoride (TFZ) by electrolysis and method of salt recovery with calcium.

Comparative analysis of Soviet and Russian school education

2020 ◽  
pp. 35-39
Author(s):  
E.A. Alexandrova ◽  
◽  
T.V. Karlova ◽  
Keyword(s):  
Comparative Analysis ◽  
Quality Of Education ◽  
Federal State ◽  
Educational Systems ◽  
Global Competitiveness ◽  
Advantages And Disadvantages ◽  
The Russian Federation ◽  
State Educational ◽  
Russian Education

Currently, the Russian Federation is implementing the national project «Education», the key goals of which are to ensure the global competitiveness of Russian education and to become one of the top 10 countries in the world in terms of quality of education. The article presents a comparative analysis of the principles of the educational systems of the Soviet and Russian schools. The article describes the key advantages and disadvantages of education in the Soviet era, which was based on ZUN (knowledge, skills). The article reveals the advantages and disadvantages of modern Russian education, the fundamental core of which is UUD (universal educational actions). The article emphasizes that, despite the introduction of the second-generation Federal state educational standards and the introduction of innovative technologies, the level of quality of education in the USSR (the Union of Soviet Socialist Republics) was higher than at present.

Mucinous adenocarcinoma of the lung presenting as pathological humeral fracture: a case report and novel surgical treatment

2021 ◽  
Vol 14 (8) ◽  
pp. e242436
Author(s):  
Rohan Prakash ◽  
Sreenadh Gella ◽  
Kanthan Theivendran
Keyword(s):  
Mucinous Adenocarcinoma ◽  
Pathological Fracture ◽  
Humeral Fracture ◽  
Operative Management ◽  
Metastatic Lesion ◽  
Pathological Fractures ◽  
Adenocarcinoma Of The Lung ◽  
Primary Neoplasm ◽  
Steel Cables ◽  
Double Plating

We present a 73-year-old woman who presented with a pathological fracture of her right humerus. Further imaging and biopsy indicated a mucinous adenocarcinoma of the lung as the primary neoplasm. This represents the first published case of a mucinous adenocarcinoma of the lung presenting as a metastatic lesion of the humerus. Operative management of pathological fractures of the humerus has typically included either intramedullary nailing or the use of single-plating or double-plating techniques. The authors describe a novel technique using both intramedullary fixation augmented with a locking plate, steel cables and bone cement, with good outcome.

scholarly journals Analysis of postoperative prognostic factors in patients with long bones metastatic lesions

2020 ◽  
Vol 101 (5) ◽  
pp. 685-690
Author(s):  
Jun Wang ◽  
N V Kharchenko ◽  
V Y Karpenko
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Bone Metastases ◽  
Bone Lesions ◽  
Long Bones ◽  
Body Parts ◽  
Limb Pain ◽  
Pathological Fractures ◽  
Metastatic Lesions

Currently, with the development of the concept of cancer treatment, the survival rate of patients has increased significantly, but the percentage of the frequency of various metastatic lesions remains high. The bones of the skeleton are one of the main parts of metastases. In cancer patients, bone metastases usually mean that the disease is at an advanced stage, and the prognosis is not good. These patients often suffer from many complications, including pain, decreased mobility, pathological fractures, etc. The quality of life of patients is seriously deteriorating. Therefore, the main goal of surgical treatment of patients with bone metastases is the earliest possible restoration the function of the affected limb, pain relief, prevention of pathological fractures and the improvement of the quality of life of patients after surgery. This literature review analyzes the incidence of bone metastases in patients, and the dependence of metastatic lesions of long tubular bones on localization incidence of bone metastases in different body parts. The domestic and foreign literature on the surgical treatment of patients with metastatic bone lesions was analyzed. The results of the analysis show that the features of surgical treatment are becoming the main factors influencing the prognosis in patients with metastatic lesions of the long bones.

scholarly journals Comparative analysis of web application performance testing tools

2020 ◽  
Vol 17 ◽  
pp. 351-357
Author(s):  
Agata Kołtun ◽  
Beata Pańczyk
Keyword(s):  
Comparative Analysis ◽  
Web Application ◽  
Web Applications ◽  
Performance Testing ◽  
Application Performance ◽  
Advantages And Disadvantages ◽  
Testing Tools ◽  
The Right ◽  
User Friendly

Recent years have brought the rise of importance of quality of developed software. Web applications should be functional, user friendly as also efficient. There are many tools available on the market for testing the performance of web applications. To help you choose the right tool, the article compares three of them: Apache JMeter, LoadNinja and Gatling. They were analyzed in terms of a user-friendly interface, parameterization of the requests and creation of own testing scripts. The research was carried out using a specially prepared application. The summary indicates the most important advantages and disadvantages of the selected tools.

scholarly journals CONTRAST-ENHANCED MRI WITH MAGNETIZATION TRANSFER EFFECT IN THE IMAGING OF BRAIN METASTATIC LESIONS

2018 ◽  
pp. 7-17
Author(s):  
A. A. Ermakova ◽  
O. Yu. Borodin ◽  
M. Yu. Sannikov ◽  
S. D. Koval ◽  
V. Yu. Usov
Keyword(s):  
Comparative Analysis ◽  
Roc Analysis ◽  
Magnetization Transfer ◽  
Metastatic Lesion ◽  
Transfer Effect ◽  
Wilcoxon Test ◽  
Post Contrast ◽  
Metastatic Lesions ◽  
The Brain ◽  
Non Parametric

Purpose: to investigate the diagnostic opportunities of contrast magnetic resonance imaging with the effect of magnetization transfer effect in the diagnosis of focal metastatic lesions in the brain.Materials and methods.The material of the study was images of contrast MRI of the brain of 16 patients (mean age 49 ± 18.5 years). Diagnosis of the direction is focal brain lesion. All MRI studies were carried out using the Toshiba Titan Octave with magnetic field of 1.5 T. The contrast agent is “Magnevist” at concentration of 0.2 ml/kg was used. After contrasting process two T1-weighted studies were performed: without T1-SE magnetization transfer with parameters of pulse: TR = 540 ms, TE = 12 ms, DFOV = 24 sm, MX = 320 × 224 and with magnetization transfer – T1-SEMTC with parameters of pulse: ΔF = −210 Hz, FA(МТС) = 600°, TR = 700 ms, TE = 10 ms, DFOV = 23.9 sm, MX = 320 × 224. For each detected metastatic lesion, a contrast-to-brain ratio (CBR) was calculated. Comparative analysis of CBR values was carried out using a non-parametric Wilcoxon test at a significance level p < 0.05. To evaluate the sensitivity and specificity of the techniques in the detection of metastatic foci (T1-SE and T1-SE-MTC), ROC analysis was used. The sample is divided into groups: 1 group is foci ≤5 mm in size, 2 group is foci from 6 to 10 mm, and 3 group is foci >10 mm.Results.Comparative analysis of CBR using non-parametric Wilcoxon test showed that the values of the CBR on T1-weighted images with magnetization transfer are significantly higher (p < 0.001) that on T1-weighted images without magnetization transfer. According to the results of the ROC analysis, sensitivity in detecting metastases (n = 90) in the brain on T1-SE-MTC and T1-SE was 91.7% and 81.6%, specificity was 100% and 97.6%, respectively. The accuracy of the T1-SE-MTC is 10% higher in comparison with the technique without magnetization transfer. Significant differences (p < 0.01) between the size of the foci detected in post-contrast T1-weighted images with magnetization transfer and in post-contrast T1-weighted images without magnetization transfer, in particular for foci ≤5 mm in size, were found.Conclusions.1. Comparative analysis of CBR showed significant (p < 0.001) increase of contrast between metastatic lesion and white matter on T1-SE-MTC in comparison with T1-SE. 2. The sensitivity, specificity and accuracy of the magnetization transfer program (T1-SE-MTC) in detecting foci of metastatic lesions in the brain is significantly higher (p < 0.01), relative to T1-SE. 3. The T1-SE-MTC program allows detecting more foci in comparison with T1-SE, in particular foci of ≤5 mm (96% and 86%, respectively, with p < 0.05).

scholarly journals COMPARATIVE ANALYSIS OF EXISTING METHODS FOR DEVELOPING CORRESPONDENCE MATRICES

2021 ◽  
Vol 1 (1) ◽  
pp. 181-182
Author(s):  
Ol'ga Lebedeva
Keyword(s):  
Comparative Analysis ◽  
Gravity Models ◽  
Mobile Technologies ◽  
Estimation Methods ◽  
Traffic Flows ◽  
Matrix Estimation ◽  
Advantages And Disadvantages

The study is aimed at comparing the methods of restoring correspondence matri ces, the traditional transport school and modern mobile technologies. Traditionally, correspondence matrices are restored by interviewing vehicle drivers and applying gravity models (to extrapolate and fill in unobserved movements), then matrix estimation methods are used to calculate traffic flows. Each of these approaches has a number of advantages and disadvantages, but there is no evidence to assess the quality of the data obtained.

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