scholarly journals Prenatal and postnatal risk factors for developing bronchopulmonary dysplasia

2011 ◽  
Vol 6 (2) ◽  
pp. 46 ◽  
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Postnatal Risk Factors

scholarly journals Risk Factors and Bronchopulmonary Dysplasia Severity. Data From the Spanish Bronchopulmonary Dysplasia Research Network

2021 ◽  
Author(s):  
Cristina Ramos-Navarro ◽  
Elena Maderuelo-Rodriguez ◽  
Ana Concheiro-Guisan ◽  
Santiago Perez-Tarazona ◽  
Santiago Rueda-Esteban ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Total Sample ◽  
Research Network ◽  
Positive Pressure ◽  
Public And Private ◽  
Postnatal Risk Factors ◽  
Type 3 ◽  
The Impact

Abstract GEIDIS is a national based research-net registry of patients with bronchopulmonary dysplasia (BPD) from public and private Spanish hospitals. It was created to provide data on the clinical characterization and follow up of infants with BPD until adulthood. The purpose of this observational study was to analyze the characteristics and the impact of perinatal risk factors on BPD severity. The study included 1,780 patients diagnosed with BPD. Of the total sample, 98.6% were premature (less than 37 weeks) and 89,4% less than 30 weeks of gestation. The median gestational age was 27.1 weeks (25.8–28.5) and median birth weight 890 g (740–1,090 g). 52.3% (n=931) were classified as mild (type 1), 25.1% (n=447) were moderate (type 2), and 22.6% (n=402) severe BPD (type 3). Most pre-and postnatal risk factors for type 2/3 BPD were associated with the length of exposure to mechanical ventilation (MV). Independent prenatal risk factors were male gender, oligohydramnios, and intrauterine growth restriction. Postnatal risk factors included the need for FiO2 of > 0.30 in the delivery room, two or more doses of surfactant administration, nosocomial pneumonia, and the length of exposure to MV. Conclusions: In this national based research-net registry of BPD patients the length of MV is the most important risk factor associated with type 2/3 BPD. Among type 3 BPD patients, those who required an FiO2 > .30 at 36 weeks’ postmenstrual age had a higher morbidity, during hospitalization and at discharge, compared to those with nasal positive pressure but FiO2 < .30.

scholarly journals Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Postnatal Risk Factors

2020 ◽  
Vol 8 ◽  
Author(s):  
Li Ding ◽  
Huawei Wang ◽  
Haifeng Geng ◽  
Ningxun Cui ◽  
Fengxia Huang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Postnatal Risk Factors

Genomic risk factors for bronchopulmonary dysplasia (BPD) in preterm neonates

2012 ◽  
Vol 224 (07) ◽  
Author(s):  
L Gortner ◽  
P Ahnert ◽  
W Göpel ◽  
P Nürnberg
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Preterm Neonates ◽  
Genomic Risk

scholarly journals Elimination of Intravenous Di-2-Ethylhexyl Phthalate Exposure Abrogates Most Neonatal Hypertension in Premature Infants with Bronchopulmonary Dysplasia

Toxics ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 75
Author(s):  
Randall Jenkins ◽  
Katia Farnbach ◽  
Sandra Iragorri
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Neonatal Intensive Care ◽  
Low Birthweight ◽  
Chi Square ◽  
Neonatal Hypertension ◽  
Vlbw Infants ◽  
Chi Square Analysis ◽  
Ethylhexyl Phthalate ◽  
Current Report

(1) Background: The incidence of hypertension in very low birthweight (VLBW) infants in a single neonatal intensive care unit (NICU) dropped markedly during a 2-year period when the IV fluid (IVF) in both the antenatal unit and the NICU temporarily changed to a di-2-ethylhexyl phthalate (DEHP)-free formulation. The objective of the current report is to document this observation and demonstrate the changes in incidence of hypertension were not associated with the variation in risk factors for hypertension; (2) Methods: The charts of all VLBW infants born in a single NICU during a 7-year span were reviewed. This time includes 32 months of baseline, 20 months of DEHP-free IVF, 20 months of IVF DEHP re-exposure, and two 4-month washout intervals. The group of interest was limited to VLBW infants with bronchopulmonary dysplasia (BPD). Chi-square analysis was used to compare incidence of hypertension among periods. Vermont Oxford NICU Registry data were examined for variation in maternal and neonatal risk factors for hypertension; Results: Incidence of hypertension in VLBW infants with BPD decreased from 7.7% (baseline) to 1.4% when IVF was DEHP-free, rising back to 10.1% when DEHP-containing IVF returned to use. Risk factors for neonatal hypertension were stable across the 3 study periods in the NICU’s group of VLBW infants; (3) Conclusions: Serendipitous removal of IVF containing DEHP resulted in near elimination of hypertension in one NICU—an effect entirely reversed after the same brand of DEHP-containing IVF returned to clinical use. These results suggest that DEHP exposure from IVF plays a major role in neonatal hypertension.

scholarly journals 1384 RISK FACTORS FOR BRONCHOPULMONARY DYSPLASIA

1985 ◽  
Vol 19 (4) ◽  
pp. 341A-341A ◽  
Author(s):  
Neil Finer ◽  
Kathrine Peters ◽  
Keith Barrington ◽  
Zamir Hayek
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia

The Use of Dexamethasone in Premature Infants at Risk for Bronchopulmonary Dysplasia or Who Already Have Developed Chronic Lung Disease: A Cautionary Note

PEDIATRICS ◽  
1991 ◽  
Vol 88 (2) ◽  
pp. 413-414
Author(s):  
LEE FRANK
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Animal Studies ◽  
Very Low Birth Weight ◽  
Double Blind Study ◽  
Dexamethasone Treatment ◽  
Double Blind ◽  
High Incidence ◽  
Potential Risk Factors ◽  
Clinical Problems

To the Editor.— The distressingly high incidence of bronchopulmonary dysplasia (BPD) in today's very low birth weight premature infant population and the prolonged morbidity and tumultuous clinical problems associated with BPD in these tiny infants have led to a trial usage of dexamethasone treatment to try to assuage these problems in this patient population. The report of Kazzi et al1 is noteworthy because the authors not only indicate in clear fashion the failure of relatively prolonged dexamethasone treatment to ameliorate the hospital course of infants with BPD (in a randomized prospective double-blind study), but they also clearly identify potential risk factors associated with dexamethasone treatment that are of concern to them as clinical investigators, risk factors based both on clinical and experimental animal studies.

scholarly journals Risk Factors for Neonatal Bronchopulmonary Dysplasia in Extremely Preterm Premature Rupture of Membranes: A Retrospective Study

2020 ◽  
Author(s):  
Eishin Nakamura ◽  
Shigetaka Matsunaga ◽  
Yoshihisa Ono ◽  
Yasushi Takai ◽  
Hiroyuki Seki
Keyword(s):  
Risk Factors ◽  
Preterm Delivery ◽  
Bronchopulmonary Dysplasia ◽  
Roc Curve ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Extremely Preterm ◽  
Gestational Week ◽  
The Mean

Abstract Background: Determination of the optimal timing for termination of pregnancy in cases of preterm premature rupture of membranes (pPROM) during the extremely preterm period is still difficult. Bronchopulmonary dysplasia (BPD) is a major disease widely taken into account when determining the prognosis of respiratory disorders in a neonate. Many aspects of this disease remain unclear. With the aim of further improving the prognosis of neonates born to mothers with pPROM, this study examined cases who were diagnosed with pPROM before 28 weeks of gestation. The study analysed risk factors for neonatal BPD. Methods: This study included 73 subjects with singleton pregnancy, diagnosed with pPROM during the gestational period from 22 weeks and 0 days to 27 weeks and 6 days. The following factors were retrospectively examined: the gestational week at which pPROM was diagnosed, the gestational week at which delivery occurred, the period for which the volume of amniotic fluid was maintained, and neonatal BPD as a complication. Receiver operating characteristic (ROC) curve analyses were conducted to analyse the relationship of the onset of BPD with the duration of oligohydramnios and the gestational weeks of delivery. Results: The mean gestational week at which a diagnosis of amniorrhexis was made was 24.5±1.9 weeks (mean±SD), and that at which delivery occurred was 27.0±3.0 weeks. Fifty-seven cases (78.1%) were diagnosed with oligohydramnios, the mean duration of which was 17.4±20.5 days. The mean birth weight of neonates was 1000±455 g, of which 49 (67.1%) were diagnosed with BPD following birth. No neonates died in this study. The ROC curve indicated that the cut-off values for the duration of oligohydramnios and gestational age at delivery were 4 days and 24.1 weeks, respectively. Multivariate analysis indicated that the duration of oligohydramnios for more than 4 days before delivery and preterm delivery at less than 24.1 weeks were risk factors for the onset of BPD. Conclusion: Our findings suggest that duration of oligohydramnios for more than 4 days before delivery and preterm delivery less than 24.1 weeks are risk factors for BPD in cases who are diagnosed with pPROM before 28 weeks of gestation.

scholarly journals Faktor Risiko Prenatal Perinatal Dan Postnatal Pada Kejadian Cerebral Palsy

2019 ◽  
Vol 8 (2) ◽  
pp. 204-209
Author(s):  
Bambang Trisnowiyanto ◽  
Yohanes Purwanto
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cerebral Palsy ◽  
Postnatal Period ◽  
Spastic Diplegia ◽  
Prenatal Risk ◽  
Prenatal Risk Factors ◽  
Spastic Hemiplegia ◽  
Postnatal Risk Factors ◽  
Observational Descriptive Study

Background: Cerebral Palsy (CP) is a disability disorder motor motorization is most common in children with a prevalence of 2-3 per 1000 live births. The term CP is explained as a group of movement and posture disorders that are often accompanied by impaired sensation, perception, cognition, communication, behavior, epilepsy, and secondary disorders of the musculoskeletal system. Disorders of CP occur in the immature central nervous system with non-progressive traits occurring in the prenatal, perinatal, and postnatal period. Methods:  The purpose of this study is to determine how much prenatal risk factors, perinatal, and postnatal events in CP at the Kitty Center Clinic in Jakarta for 5 year (2013 - 2017). Result: An observational descriptive study, which described prenatal perinatal, and postnatal risk factors for CP events at the Kitty Center Clinic in Jakarta for a period of 5 years (2013-2017) with a total of 523 study subjects. Based on the analysis of data obtained, based on the type of CP 35% quadripelgia spastic, 36% spastic diplegia, 6% spastic hemiplegia, 9% athetosis, and 14% hypotonia. Based on sex 62% are men, and 38% are women with a ratio of 1.6: 1.0. Based on the age of the child 11% <2 years, 34% 3-6 years, 33% 7-12 years, and 22%13-18 years. Conclusion:  Based on risk factors of 62% prenatal, 25% perinatal, and 12% postnatal. Prenatal risk factor is the biggest risk factor as much as 62% which causes Cerebral Palsy at the Kitty Center Clinic in Jakarta.

scholarly journals Pre-, peri- and postnatal risk factors associated with gender in children with autism

2012 ◽  
Vol 5 (2) ◽  
pp. 77-90 ◽  
Author(s):  
Dary Luz Lara Correa ◽  
Oscar Utria Rodríguez ◽  
José Hernando Ávila-Toscano
Keyword(s):  
Risk Factors ◽  
Cognitive Activity ◽  
Children With Autism ◽  
Parental Relationships ◽  
Chi Square ◽  
Pregnancy And Childbirth ◽  
Prenatal Factors ◽  
Postnatal Risk Factors ◽  
Clinical Records ◽  
The Relationship

This study was undertaken in order to identify the relationship between gender of children with autism and risk factors before/during pregnancy and childbirth. An analysis of 66 clinical records was divided into two groups defined by gender of children diagnosed with autism in Bogotá (Colombia). The data were collected with the Maternal Perinatal Risk Questionnaire and analyzed with Pearson Chi square. The most significant risks associated with gender in the minors were voluntary abortions, maternal difficulties in a previous pregnancy, surgery during pregnancy, conflicting parental relationships, demanding physical and cognitive activity, consumption of drugs in the mother, duration of pregnancy and birth weight. Among men there was as many prenatal factors while among girls had an enrollment over perinatal factors (before and during labor) and psychosocial.

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