scholarly journals Prenatal and postnatal exposure to ambient air pollution and asthma in neonatal jaundice infants

2022 ◽  
Author(s):  
Hao-Wei Chung ◽  
Chih-Hsing Hung ◽  
Fu-Chen Kuo ◽  
Hui-Min Hsieh ◽  
Chung-Hsiang Li ◽  
...  
Keyword(s):  
Childhood Asthma ◽  
Air Pollutants ◽  
Neonatal Jaundice ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Total Serum ◽  
Research Database ◽  
Postnatal Exposure ◽  
Ambient Air Pollutants ◽  
Increased Risk

Background: Both air pollutants and neonatal jaundice (NJ) have known effects on childhood asthma, but higher total serum bilirubin (TSB) level was associated with lung protection. This study aimed to assess whether prenatal/postnatal exposure to air ambient pollutants is related to the inception of asthma in NJ infants. Material and methods: A nested case-control retrospective study of NJ infants was performed on the Kaohsiung Medical University Hospital Research Database between 2009 and 2019. The average concentration of particulate matter (PM2.5), sulfur dioxide (SO2), nitric dioxide (NO2) for six months, first and second years after the birth, and first, second and third trimesters prenatally were analyzed. The mild and significant NJ infants were categorized as TSB level < and ≧12 mg/dl, respectively. Asthma was defined as a diagnosis with medication. The adjusted odds ratio (aOR) and 95% confidence interval (CI) present the relationship between study periods and childhood asthma. Results: SO2 and NO2 exposure during prenatal periods were significantly associated with increased risk of childhood asthma in mild NJ infants (aOR (95% CI)), SO2: 1.20-1.34 (1.05-1.56); NO2: 1.06-1.07 (1.01-1.13)). Effects were more pronounced in postnatal exposure to three ambient air pollutants in mild jaundice infants. (aOR (95% CI), SO2: 1.33-1.41 (1.14-1.69); NO2: 1.07-1.31 (1.01-1.49; PM2.5:1.05 (1.00-1.10) Conclusion: Both SO2 and NO2 during prenatal and postnatal exposure in mild NJ infants were associated with childhood asthma. Whether taken phototherapy or not, significant NJ infants were spared by three ambient air pollutants.

scholarly journals Association between early prenatal exposure to ambient air pollution and birth defects: evidence from newborns in Xi’an, China

2018 ◽  
Vol 41 (3) ◽  
pp. 494-501 ◽  
Author(s):  
Lingling Wang ◽  
Xiaomei Xiang ◽  
Baibing Mi ◽  
Hui Song ◽  
Min Dong ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Cleft Palate ◽  
Birth Defects ◽  
Air Pollutants ◽  
Congenital Heart ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Ambient Air Pollutants ◽  
Increased Risk

Abstract Background The aim of this study was to investigate an association between birth defects and exposure to sulfur dioxide (SO2), nitrogen dioxide (NO2) and particles ≤10 μm in an aerodynamic diameter (PM10) during early pregnancy in Xi’an, China. Methods Birth defect data were from the Birth Defects Monitoring System of Xi’an, and data on ambient air pollutants during 2010–15 were from the Xi’an Environmental Protection Bureau. A generalized additive model (GAM) was used to investigate the relationship between birth defects and ambient air pollutants. Results Among the 8865 cases with birth defects analyzed, the overall incidence of birth defects was 117.33 per 10 000 infants. Ambient air pollutant exposure during the first trimester increased the risk of birth defects by 10.3% per 10 μg/m3 increment of NO2 and 3.4% per 10 μg/m3 increment of PM10. No significant association was found between birth defects and SO2. Moreover, NO2 increased risk of neural tube defects, congenital heart disease, congenital polydactyly, cleft palate, digestive system abnormalities and gastroschisis, and PM10 was associated with congenital heart disease and cleft lip with or without cleft palate. Conclusions Chinese women should avoid exposure to high levels of NO2 and PM10 during the first 3 months of pregnancy.

scholarly journals Relationship between Air Pollutant Exposure and Gynecologic Cancer Risk

2021 ◽  
Vol 18 (10) ◽  
pp. 5353
Author(s):  
Qiwei Yu ◽  
Liqiang Zhang ◽  
Kun Hou ◽  
Jingwen Li ◽  
Suhong Liu ◽  
...  
Keyword(s):  
Air Pollution ◽  
Cancer Risk ◽  
Air Pollutants ◽  
Gynecological Cancer ◽  
Gynecologic Cancer ◽  
Ambient Air ◽  
Air Pollutant ◽  
Ambient Air Pollution ◽  
Short Term Exposure ◽  
Increased Risk

Exposure to air pollution has been suggested to be associated with an increased risk of women’s health disorders. However, it remains unknown to what extent changes in ambient air pollution affect gynecological cancer. In our case–control study, the logistic regression model was combined with the restricted cubic spline to examine the association of short-term exposure to air pollution with gynecological cancer events using the clinical data of 35,989 women in Beijing from December 2008 to December 2017. We assessed the women’s exposure to air pollutants using the monitor located nearest to each woman’s residence and working places, adjusting for age, occupation, ambient temperature, and ambient humidity. The adjusted odds ratios (ORs) were examined to evaluate gynecologic cancer risk in six time windows (Phase 1–Phase 6) of women’s exposure to air pollutants (PM2.5, CO, O3, and SO2) and the highest ORs were found in Phase 4 (240 days). Then, the higher adjusted ORs were found associated with the increased concentrations of each pollutant (PM2.5, CO, O3, and SO2) in Phase 4. For instance, the adjusted OR of gynecological cancer risk for a 1.0-mg m−3 increase in CO exposures was 1.010 (95% CI: 0.881–1.139) below 0.8 mg m−3, 1.032 (95% CI: 0.871–1.194) at 0.8–1.0 mg m−3, 1.059 (95% CI: 0.973–1.145) at 1.0–1.4 mg m−3, and 1.120 (95% CI: 0.993–1.246) above 1.4 mg m−3. The ORs calculated in different air pollution levels accessed us to identify the nonlinear association between women’s exposure to air pollutants (PM2.5, CO, O3, and SO2) and the gynecological cancer risk. This study supports that the gynecologic risks associated with air pollution should be considered in improved public health preventive measures and policymaking to minimize the dangerous effects of air pollution.

scholarly journals Short-Term Effects of Ambient Air Pollution on Hospitalization for Respiratory Disease in Taiyuan, China: A Time-Series Analysis

2018 ◽  
Vol 15 (10) ◽  
pp. 2160 ◽  
Author(s):  
Lisha Luo ◽  
Yunquan Zhang ◽  
Junfeng Jiang ◽  
Hanghang Luan ◽  
Chuanhua Yu ◽  
...  
Keyword(s):  
Air Pollution ◽  
Time Series ◽  
Respiratory Disease ◽  
Air Pollutants ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
High Risk Population ◽  
Short Term ◽  
Ambient Air Pollutants ◽  
Short Term Effects

In this study, we estimated the short-term effects of ambient air pollution on respiratory disease hospitalization in Taiyuan, China. Daily data of respiratory disease hospitalization, daily concentration of ambient air pollutants and meteorological factors from 1 October 2014 to 30 September 2017 in Taiyuan were included in our study. We conducted a time-series study design and applied a generalized additive model to evaluate the association between every 10-μg/m3 increment of air pollutants and percent increase of respiratory disease hospitalization. A total of 127,565 respiratory disease hospitalization cases were included in this study during the present period. In single-pollutant models, the effect values in multi-day lags were greater than those in single-day lags. PM2.5 at lag02 days, SO2 at lag03 days, PM10 and NO2 at lag05 days were observed to be strongly and significantly associated with respiratory disease hospitalization. No significant association was found between O3 and respiratory disease hospitalization. SO2 and NO2 were still significantly associated with hospitalization after adjusting for PM2.5 or PM10 into two-pollutant models. Females and younger population for respiratory disease were more vulnerable to air pollution than males and older groups. Therefore, some effective measures should be taken to strengthen the management of the ambient air pollutants, especially SO2 and NO2, and to enhance the protection of the high-risk population from air pollutants, thereby reducing the burden of respiratory disease caused by ambient air pollution.

scholarly journals Short-term effects of air pollution on blood pressure

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
You-Jung Choi ◽  
Sun-Hwa Kim ◽  
Si-Hyuck Kang ◽  
Sun-Young Kim ◽  
Ok-Jin Kim ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Air Pollution ◽  
Air Pollutants ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Pathophysiological Mechanism ◽  
Short Term ◽  
Mortality And Morbidity ◽  
Short Term Exposure ◽  
Increased Risk

AbstractElevated blood pressure (BP) has been proposed as a possible pathophysiological mechanism linking exposure to ambient air pollution and the increased risk of cardiovascular mortality and morbidity. In this study, we investigated the hourly relationship between ambient air pollutants and BP. BP measurements were extracted from the electronic health record database of the Seoul National University Bundang Hospital from February 2015 to June 2017. A total of 98,577 individual BP measurements were matched to the hourly levels of air pollutants. A generalized additive model was constructed for hour lags of 0–8 of air pollutants adjusting for age, sex, meteorological variables, and time trend. Systolic BP was shown to be significantly lower at 2–4 hours and 3–5 hours after increased levels of SO2 and CO, respectively (0.24 mmHg and 0.26 mmHg for an interquartile range, respectively). In contrast, O3 and NO2 were associated with significantly increased systolic BP at 3–5 lag hours and at 0–2 lag hours, respectively. BP elevation in association with O3 and NO2 was shown to be significantly greater in hypertensive patients than normotensive subjects. Our findings suggest that short-term exposure to air pollution may be associated with elevated BP.

scholarly journals Ambient Air Pollution and Hospital Admissions for Peptic Ulcers in Taipei: A Time-Stratified Case-Crossover Study

2019 ◽  
Vol 16 (11) ◽  
pp. 1916 ◽  
Author(s):  
Shang-Shyue Tsai ◽  
Hui-Fen Chiu ◽  
Chun-Yuh Yang
Keyword(s):  
Air Pollution ◽  
Peptic Ulcer ◽  
Crossover Study ◽  
Air Pollutants ◽  
Hospital Admissions ◽  
Ambient Air ◽  
Air Pollutant ◽  
Ambient Air Pollution ◽  
Research Database ◽  
Case Crossover

Very few studies have been performed to determine whether there is a relationship between air pollution and increases in hospitalizations for peptic ulcer, and for those that have occurred, their results may not be completely relevant to Taiwan, where the mixture of ambient air pollutants differ. We performed a time-stratified case-crossover study to investigate the possible association between air pollutant levels and hospital admissions for peptic ulcer in Taipei, Taiwan. To do this, we collected air pollution data from Taiwan's Environmental Protection Agency and hospital admissions for peptic ulcer data for the years 2009–2013 from Taiwan's National Health Insurance's research database. We used conditional logistic regression to analyze the possible association between the two, taking temperature and relative humidity into account. Risk was expressed as odds ratios and significance was expressed with 95% confidence intervals. In our single pollutant model, peptic ulcer admissions were significantly associated with all pollutants (PM10, PM2.5, SO2, NO2, CO, and O3) on warm days (>23 °C). On cool days (<23 °C), peptic ulcer admissions were significantly associated with PM10, NO2, and O3. In our two-pollutant models, peptic ulcer admissions were significantly associated NO2 and O3 when combined with each of the other pollutants on warm days, and with PM10, NO2, and O3 on cool days. It was concluded that the likelihood of peptic ulcer hospitalizations in Taipei rose significantly with increases in air pollutants during the study period.

The relationships between ambient air pollutants and childhood asthma and eczema are modified by emotion and conduct problems

2013 ◽  
Vol 23 (12) ◽  
pp. 778-783.e3 ◽  
Author(s):  
Cailiang Zhou ◽  
Nour Baïz ◽  
Soutrik Banerjee ◽  
Denis André Charpin ◽  
Denis Caillaud ◽  
...  
Keyword(s):  
Conduct Problems ◽  
Childhood Asthma ◽  
Air Pollutants ◽  
Ambient Air ◽  
Ambient Air Pollutants

scholarly journals Obesity and the relation between joint exposure to ambient air pollutants and incident type 2 diabetes: A cohort study in UK Biobank

PLoS Medicine ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. e1003767
Author(s):  
Xiang Li ◽  
Mengying Wang ◽  
Yongze Song ◽  
Hao Ma ◽  
Tao Zhou ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Air Pollution ◽  
Air Pollutants ◽  
Ambient Air ◽  
Uk Biobank ◽  
Ambient Air Pollutants ◽  
Obesity Status ◽  
Increased Risk ◽  
The Relationship

Background Air pollution has been related to incidence of type 2 diabetes (T2D). We assessed the joint association of various air pollutants with the risk of T2D and examined potential modification by obesity status and genetic susceptibility on the relationship. Methods and findings A total of 449,006 participants from UK Biobank free of T2D at baseline were included. Of all the study population, 90.9% were white and 45.7% were male. The participants had a mean age of 56.6 (SD 8.1) years old and a mean body mass index (BMI) of 27.4 (SD 4.8) kg/m2. Ambient air pollutants, including particulate matter (PM) with diameters ≤2.5 μm (PM2.5), between 2.5 μm and 10 μm (PM2.5–10), nitrogen oxide (NO2), and nitric oxide (NO) were measured. An air pollution score was created to assess the joint exposure to the 4 air pollutants. During a median of 11 years follow-up, we documented 18,239 incident T2D cases. The air pollution score was significantly associated with a higher risk of T2D. Compared to the lowest quintile of air pollution score, the hazard ratio (HR) (95% confidence interval [CI]) for T2D was 1.05 (0.99 to 1.10, p = 0.11), 1.06 (1.00 to 1.11, p = 0.051), 1.09 (1.03 to 1.15, p = 0.002), and 1.12 (1.06 to 1.19, p < 0.001) for the second to fifth quintile, respectively, after adjustment for sociodemographic characteristics, lifestyle factors, genetic factors, and other covariates. In addition, we found a significant interaction between the air pollution score and obesity status on the risk of T2D (p-interaction < 0.001). The observed association was more pronounced among overweight and obese participants than in the normal-weight people. Genetic risk score (GRS) for T2D or obesity did not modify the relationship between air pollution and risk of T2D. Key study limitations include unavailable data on other potential T2D-related air pollutants and single-time measurement on air pollutants. Conclusions We found that various air pollutants PM2.5, PM2.5–10, NO2, and NO, individually or jointly, were associated with an increased risk of T2D in the population. The stratified analyses indicate that such associations were more strongly associated with T2D risk among those with higher adiposity.

scholarly journals Pre- and postnatal exposure to multiple ambient air pollutants and child behavioral problems at five years of age

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Jiyoung Shin ◽  
Hyesook Park ◽  
Hae Soon Kim ◽  
Eui Jung Kim ◽  
Kyoung Nam Kim ◽  
...  
Keyword(s):  
Behavioral Problems ◽  
Air Pollutants ◽  
Ambient Air ◽  
Postnatal Exposure ◽  
Ambient Air Pollutants ◽  
Child Behavioral Problems

scholarly journals Association Between Ambient Air Pollutants Exposure and Preterm Birth in Women Who Underwent in vitro Fertilization: A Retrospective Cohort Study From Hangzhou, China

2021 ◽  
Vol 8 ◽  
Author(s):  
Wenming Shi ◽  
Meiyan Jiang ◽  
Lena Kan ◽  
Tiantian Zhang ◽  
Qiong Yu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Birth ◽  
Retrospective Cohort Study ◽  
Air Pollutants ◽  
Retrospective Cohort ◽  
Oocyte Retrieval ◽  
Ambient Air ◽  
Ambient Air Pollutants ◽  
Increased Risk

Objectives: Exposure to air pollutants has been linked to preterm birth (PTB) after natural conception. However, few studies have explored the effects of air pollution on PTB in patients who underwent in vitro fertilization (IVF). We aimed to investigate the association between ambient air pollutants exposure and PTB risk in IVF patients.Methods: This retrospective cohort study included 2,195 infertile women who underwent IVF treatment from January 2017 and September 2020 in Hangzhou Women's Hospital. Totally 1,005 subjects who underwent a first fresh embryo(s) transfer cycle were analyzed in this study. Residential exposure to ambient six air pollutants (PM2.5, PM10, SO2, NO2, CO, O3) during various periods of the IVF timeline were estimated by satellite remote-sensing and ground measurement. Cox proportional hazards models for discrete time were used to explore the association between pollutants exposure and incident PTB, with adjustment for confounders. Stratified analyses were employed to explore the effect modifiers.Results: The clinical pregnancy and PTB rates were 61.2 and 9.3%, respectively. We found that PM2.5 exposure was significantly associated with an increased risk of PTB during 85 days before oocyte retrieval [period A, adjusted hazard ratio, HR=1.09, 95%CI: 1.02–1.21], gonadotropin start to oocyte retrieval [period B, 1.07 (1.01–1.19)], first trimester of pregnancy [period F, 1.06 (1.01–1.14)], and the entire IVF pregnancy [period I, 1.07 (1.01–1.14)], respectively. An interquartile range increment in PM10 during periods A and B was significantly associated with PTB at 1.15 (1.04–1.36), 1.12 (1.03–1.28), and 1.14 (1.01–1.32) for NO2 during period A. The stratified analysis showed that the associations were stronger for women aged &lt;35 years and those who underwent two embryos transferred.Conclusions: Our study suggests ambient PM2.5, PM10, and NO2 exposure were significantly associated with elevated PTB risk in IVF patients, especially at early stages of IVF cycle and during pregnancy.

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