scholarly journals The impact of puffball autolysis on selected chemical and biological properties: Puffball extracts as potential ingredients of skin-care products

2019 ◽  
Vol 71 (4) ◽  
pp. 721-733 ◽  
Author(s):  
Predrag Petrovic ◽  
Katarina Ivanovic ◽  
Aleksandra Jovanovic ◽  
Milica Simovic ◽  
Violeta Milutinovic ◽  
...  

Puffballs are fungi that produce globose fruiting bodies that undergo autolysis, transforming their insides into a spore bearing, powdery mass. Mature fruiting bodies are traditionally used to treat open skin wounds. In this study, methanol extracts of two puffball species, Handkea excipuliformis and Vascellum pratense, were examined and compared in order to provide insight into the changes these mushrooms undergo during maturation, with respect to their potential use in skin care and wound treatment. Some compounds involved in skin care and regeneration were quantified, and it was found that maturation increases the concentrations of almost all of these compounds. Antioxidant activity was also more pronounced in mature fruiting body extracts, which was in correlation with the higher content of antioxidants. Tyrosinase inhibition was vastly improved with autolysis, correlating with the higher phenolic content in mature fruiting body extracts. Antimicrobial activity was negatively affected by autolysis in the case of H. excipuliformis, whereas autolysis had little effect on the antimicrobial activity of V. pratense. Autolysis generally improved the biological activity and increased the concentrations of compounds involved in skin care, which justifies the traditional use of puffballs and makes them good candidates for various potential cosmetic and medicinal skin-care products.

BMC Biology ◽  
2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Amina Bouslimani ◽  
Ricardo da Silva ◽  
Tomasz Kosciolek ◽  
Stefan Janssen ◽  
Chris Callewaert ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4778
Author(s):  
Sylwia Zielińska ◽  
Magdalena Dziągwa-Becker ◽  
Adam Junka ◽  
Ewelina Piątczak ◽  
Anna Jezierska-Domaradzka ◽  
...  

The antimicrobial properties of herbs from Papaveraceae have been used in medicine for centuries. Nevertheless, mutual relationships between the individual bioactive substances contained in these plants remain poorly elucidated. In this work, phytochemical composition of extracts from the aerial and underground parts of five Papaveraceae species (Chelidonium majus L., Corydalis cava (L.) Schweigg. and Körte, C. cheilanthifolia Hemsl., C. pumila (Host) Rchb., and Fumaria vaillantii Loisel.) were examined using LC-ESI-MS/MS with a triple quadrupole analyzer. Large differences in the quality and quantity of all analyzed compounds were observed between species of different genera and also within one genus. Two groups of metabolites predominated in the phytochemical profiles. These were isoquinoline alkaloids and, in smaller amounts, non-phenolic carboxylic acids and phenolic compounds. In aerial and underground parts, 22 and 20 compounds were detected, respectively. These included: seven isoquinoline alkaloids: protopine, allocryptopine, coptisine, berberine, chelidonine, sanguinarine, and chelerythrine; five of their derivatives as well as non-alkaloids: malic acid, trans-aconitic acid, quinic acid, salicylic acid, trans-caffeic acid, p-coumaric acid, chlorogenic acid, quercetin, and kaempferol; and vanillin. The aerial parts were much richer in phenolic compounds regardless of the plant species. Characterized extracts were studied for their antimicrobial potential against planktonic and biofilm-producing cells of S. aureus, P. aeruginosa, and C. albicans. The impact of the extracts on cellular metabolic activity and biofilm biomass production was evaluated. Moreover, the antimicrobial activity of the extracts introduced to the polymeric carrier made of bacterial cellulose was assessed. Extracts of C. cheilanthifolia were found to be the most effective against all tested human pathogens. Multiple regression tests indicated a high antimicrobial impact of quercetin in extracts of aerial parts against planktonic cells of S. aureus, P. aeruginosa, and C. albicans, and no direct correlation between the composition of other bioactive substances and the results of antimicrobial activity were found. Conclusively, further investigations are required to identify the relations between recognized and unrecognized compounds within extracts and their biological properties.


Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4129 ◽  
Author(s):  
Joanna Kozłowska ◽  
Bartłomiej Potaniec ◽  
Dagmara Baczyńska ◽  
Barbara Żarowska ◽  
Mirosław Anioł

A series of 18 aminochalcone derivatives were obtained in yields of 21.5–88.6% by applying the classical Claisen-Schmidt reaction. Compounds 4–9, 14 and 16–18 with 4-ethyl, 4-carboxy-, 4-benzyloxy- and 4-benzyloxy-3-methoxy groups were novel, not previously described in the scientific literature. To determine the biological properties of the synthesized compounds, anticancer and antimicrobial activity assays were performed. Antiproliferative potential was evaluated on four different human colon cancer cell lines—HT-29, LS180, LoVo and LoVo/DX —using the SRB assay and compared with green monkey kidney fibroblasts COS7. Anticancer activity was described as the IC50 value. The best results were observed for 2′-aminochalcone (1), 3′-aminochalcone (2) and 4′-aminochalcone (3) (IC50 = 1.43–1.98 µg·mL−1) against the HT-29 cell line and for amino-nitrochalcones 10–12 (IC50 = 2.77–3.42 µg·mL−1) against the LoVo and LoVo/DX cell lines. Moreover, the antimicrobial activity of all derivatives was evaluated on two strains of bacteria: Escherichia coli ATCC10536 and Staphylococcus aureus DSM799, the yeast strain Candida albicans DSM1386 and three strains of fungi: Alternaria alternata CBS1526, Fusarium linii KB-F1 and Aspergillus niger DSM1957. In the case of E. coli ATCC10536 almost all derivatives hindered the bacterial growth (∆OD = 0). Furthermore, the best results were observed in the presence of 4′-aminochalcone (3), that completely limited the growth of all tested strains at the concentration range of 0.25–0.5 mg·mL−1. The strongest bacteriostatic activity was exhibited by novel 3′-amino-4-benzyloxychalcone (14), that prevented the growth of E. coli ATCC10536 with MIC = 0.0625 mg·mL−1.


2021 ◽  
Author(s):  
Okta Nurvia ◽  
Budi Sarasati

In this pandemic era, beauty vloggers play a significant role, influencing consumer preferences and attitudes. This paper seeks to determine the impact of Reference Groups by beauty vloggers on the purchasing decisions by female students involving skin care products who follow beauty vloggers in Bekasi. The study uses correlational quantitative research, and the objective is to see the extent to which variations in a variable are related to one or more other variables based on the correlation coefficient. The respondent pool was comprised of 100 female students, obtained via purposive sampling. The results showed a significance of 0.000 <0.05. The value of R2 (R square) 0.290 shows the effect of X variable (reference groups) on Y variable (purchase decision) by 29%. The conclusion of this research is that beauty vloggers significantly influence the decision to buy skin care products. Keywords: Beauty Vloggers, Purchase Decision, Reference Groups


2015 ◽  
Vol 11 (1) ◽  
Author(s):  
Norazila Abd Aziz ◽  
Mohamad Fitri S ◽  
Rethinasamy Soubakeavathi

Children today are labeled as Digital Natives, because they are born into an era where ICT has already permeated almost all layers of societies around the world. However, digital gaps among children still exist, particularly for those born into underprivileged remote rural communities. Making technology accessible for all learners, irrespective of their geographical locations, is often viewed as the means for narrowing, if not eliminating digital divide. Presence of technology would definitely generate interest and discussion about its potential use especially among learners from rural remote locations. However, the debate is still open about the feasibility and capability of technology to initiate meaningful learning. This paper describes part of an on-going research to investigate the impact of using technology to supplement classroom learning among children of remote rural locations in Sarawak, Malaysia. One of the key goals of the project is to develop a technology literacy programme in an informal learning setting using localized content which are selected and built to sustain and enhance local cultures, beliefs and traditions that already exist in these remote rural locations. This project also investigates the factors that need to be addressed when planning, designing and sustaining informal learning experiences using technology for children of various ethnic groups, languages, beliefs and cultures.


2020 ◽  
Vol 76 ◽  
pp. 01036
Author(s):  
Priscilla Evelyn Budiono ◽  
Dhyah Harjanti ◽  
Karina Stankevica

Skincare business in Indonesia has been growing enormously in the last decade, with the coming of international brands and the struggling of local brands, to win the Indonesian customers. The aim of this research is to analyze the influence of country of origin to purchase decision through the brand image, and the impact of country of origin on customer satisfaction for local Indonesian skin care brands. As this research is using the quantitative approach, the data are collected by using questionnaires which are distributed to selected samples of 179 respondents. The respondents are chosen from the consumers of Indonesian brands of skin care products. The data are analyzed with SmartPLS software. The results show that the country of origin has a positive influence to purchase decision, the country of origin has a positive influence on brand image, brand image has a positive influence on purchase decision, and, finally, brand image has a positive influence on customer satisfaction on local Indonesian brands of skin care products.


2020 ◽  
Vol 24 (3 Part A) ◽  
pp. 1705-1712
Author(s):  
Xiaochen Yue ◽  
Hongqi Yang ◽  
Ting Wang ◽  
Shuaiwei Dong ◽  
Zhiyong Sun ◽  
...  

The potential use of organic solvent extracts of Diospyros lotus L. was analyzed by using FT-IR, GC-MS, and MTT. The results showed that the Diospyros lotus L. extracts contained many kinds of bioactive organic ingredients with antibacterial, antitumor, and anti-inflammatory activities. Meanwhile the extracts have significant effect on HEGP2 and SGC-7091, whicn can be used as anticancer medicine. Therefore, it provides a scientific foundation for potential application prospects in the fields of biomedicine, skin care products and other fields.


2018 ◽  
Vol 12 ◽  
pp. 117822341775277 ◽  
Author(s):  
Antoine Berger ◽  
Carlos Regueiro ◽  
Tarek Hijal ◽  
David Pasquier ◽  
Cristina De La Fuente ◽  
...  

Purpose: As many as 50% of patients with cancer develop acute skin reactions to some degree with radiotherapy. Proactive skin care is often recommended to minimise these skin reactions and maintain the integrity of the epidermal barrier; nevertheless, no consensual guidelines are systematically used. This multicentre, observational, prospective study evaluated the tolerability and benefit of supportive and barrier protective skin care products in preventing radiotherapy-induced skin reactions in 253 women initiating radiotherapy (exclusive or adjuvant) for breast cancer. Methods: Patients received a kit of 5 commercially available skin care products before the first radiotherapy treatment. The following variables were assessed: cutaneous adverse events, investigator-assessed skin reactions (oedema, erythema, dryness, desquamation) before and after radiotherapy course, investigator, and patient opinion on products benefit. Results were analysed by frequency of product use (heavy versus low). Results: Average age was 60 years (range: 34-85). Over 92% of patients reported good to excellent tolerance on irradiated skin for each product. During the 6-week radiotherapy period, we observed that heavy product users had less skin reactions than the low users, particularly within 10 days of radiotherapy initiation (8% versus 18%; p = .031). Positive physician’s opinion on product use was more frequent for high (66.6%) versus low (32%) users. Patient-assessed patient benefit index was generally >1, indicating relevant treatment benefit, with a tendency for better benefit in high versus low users. Conclusions: These results support recommendations to use skin care products to minimise the impact of secondary cutaneous reactions with radiotherapy cancer treatment.


2020 ◽  
Vol 24 (3 Part A) ◽  
pp. 1633-1639
Author(s):  
Hong-Qi Yang ◽  
Guang-Hui Chen ◽  
Shuaiwei Dong ◽  
Zhiyong Sun ◽  
Yaoming Wang ◽  
...  

The potential use of leaves of Diospyros lotus L. was analyzed by using FT-IR, GC-MS and MTT through organic solvent extracts. The results showed that the leaves extracts of Diospyros lotus L. contains many kinds of bioactive organic ingredients with antibacterial, antitumor, and anti-inflammatory activities. Meanwhile the extracts have significant effect on HEGP2, SGC-7091, and K562. Therefore, it provides a scientific foundation for comprehensive application prospects in the fields of biomedicine, food, skin care products and other fields and turning waste into treasure.


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