scholarly journals Hormones and female sexuality

2003 ◽  
Vol 56 (9-10) ◽  
pp. 446-450 ◽  
Author(s):  
Artur Bjelica ◽  
Aleksandra Kapamadzija ◽  
Milana Maticki-Sekulic

Introduction In contrast to animal species in which linear relationships exist between hormonal status and sexual behaviour sexuality in human population is not determined so simply by the level of sexual steroids. The article analyses female sexuality in the light of hormonal status. Administration of sexual steroids during pregnancy and sexual differentiation High doses of gestagens, especially those with high androgen activity, widely used against miscarriages may lead to tomboys, but without differences in sexual orientation. However, it has been observed that the frequency of bisexual and lesbian women is higher in women with congenital adrenogenital syndrome. Hormones sexual desire and sexuality during menstrual cycle It has been established that sexual desire, autoeroticism and sexual fantasies in women depend on androgen levels. There are a lot of reports claiming that sexual desire varies during the menstrual cycle. Hormonal contraception and sexuality Most patients using birth control pills present with decreased libido. But, there are reports that progestagens with antiandrogenic effect in contraceptive pills do not affect sexual desire. Hormonal changes in peri- and postmenopausal period and sexuality Decreased levels of estrogen and testosterone in older women are associated with decreased libido, sensitivity and erotic stimuli. Sexuality and hormone replacement therapy Hormonal therapy with estrogen is efficient in reference to genital atrophy, but not to sexual desire. Really increased libido is achieved using androgens. Also, therapy with dehydroepiandrosterone (DHEA) and tibolone have positive effects on female libido. Conclusion Effect of sexual steroids on sexual sphere of women is very complex. The association between hormones and sexuality is multidimensional, as several hormones are important in regulation of sexual behaviour. Still, it should be pointed out that sexuality is in the domain of hormonal, emotional-motivational and social factors.

2006 ◽  
Vol 59 (1-2) ◽  
pp. 38-45 ◽  
Author(s):  
Srdjan Boskovic ◽  
Aleksandar Neskovic

Introduction. The natural history of atherosclerosis can be assessed using different methods including quantitative coronary angiography, intravascular ultrasound, B-mode ultrasound, electron-beam computed tomography and magnetic resonance imaging. Regression of atherosclerosis. Although the first investigations regarding effects of low cholesterol diet on atherosclerosis progression in animals were performed almost 100 years ago, researches on potential induction of atherosclerosis regression in humans began only recently, in the past 20 years. To date, many studies assessing different drugs and study protocols on natural evolution of atherosclerosis have been performed. They include use of diet and physical activity, different hypolipemic drugs, especially statins, ACE inhibitors, calcium channel blockers, hormone replacement therapy, antioxidants, and recently, use of recombinant apolipoproteins. Statins and atherosclerosis. It has been established that statins given to patients with, or even without verified coronary artery disease, slow progression of atherosclerosis. These effects of statins are likely due to a combination of their metabolic and pleiotropic properties and might in part explain the positive effects of these drugs on overall cardiovascular mortality and morbidity. Furthermore, applied in high doses, these drugs may induce real atherosclerosis regression, especially in asymptomatic patients in the early stages of the disease. .


1988 ◽  
Vol 17 (6) ◽  
pp. 499-508 ◽  
Author(s):  
Harold Stanislaw ◽  
Frank J. Rice

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Y Anzawa ◽  
T Nagasaki ◽  
Y Kasagi ◽  
C Kato ◽  
Y Omi ◽  
...  

Abstract Study question Do culture results of eggs obtained by double stimulation (DuoStim), where eggs are collected twice in one cycle, differ from a conventional fertility drug method? Summary answer The culture results of eggs acquired via the DuoStim cycle versus those acquired via a widely used conventional fertility drug method did not differ significantly. What is known already For patients with reduced ovarian reserve, the random start method, in which ovarian stimulation can start at any time during the menstrual cycle, is being used. As the pituitary gland is suppressed by progesterone during the luteal phase, endogenous luteinizing hormone surges are less likely to occur and ovulation is more easily avoidable. Previous reports showed that ovarian stimulation during the follicular and luteal phases of the same menstrual cycle resulted in similar blastocyst formation rates with normal chromosome numbers, which seems to be time-consuming. The DuoStim method is considered useful in cases in which time is at a premium. Study design, size, duration Between June 2019–December 2020, 562 egg collection cycles were performed in women ≥36 years. Ovulation cycles were evaluated in the conventional ovulation induction cycle (Co) group and DuoStim cycle (DS) group (subclassified into D1 group [first egg collection in cycle] and D2 group [second egg collection]. Post-insemination culture results were evaluated. Participants/materials, setting, methods Participants were women ≥36 years. Infusion method was IVF, and blastocysts of Gardner classification 3BB or higher were designated as good blastocysts, and blastocysts of 3AA or higher were designated as the best blastocysts. Confirmation of the fetal sac was defined as clinical pregnancy for the single freeze-thaw blastocyst transplant cycle. Chi-square and t-tests were used for statistical analysis. P ≤ 0.05 indicated statistical significance. Main results and the role of chance The average number of eggs acquired per cycle was 6.9 in the Co group and 3.5 in the DS group, and the egg maturation rate was 88.0% in the Co group and 95.7% in the DS group, which showed significant differences. The 2PN rate, blastocyst arrival rate, and Day 5 good blastocyst arrival rate in the obtained mature eggs were 66.5%, 66.5%, and 38.3% in the Co group and 70.9%, 70.5%, and 34.4% in the DS group and were not significantly different. Similarly, when a comparative study was conducted between the D1 group and D2 group, rates were 67.5%, 69.0%, and 31.0% in the D1 group and 74.4%, 71.9%, and 37.5% in the D2 group, with no significant difference noted. Rates of clinical pregnancy and post-transplantation miscarriage were 41.1% and 17.8% in the Co group and 16.6% and 0% in the DS group, respectively, with no significant difference, although rates in the Co group tended to be better. Limitations, reasons for caution The fertilization method was evaluated only by IVF. The transplantation method was freeze-thaw embryo transfer by hormone replacement cycle, and the target age was 36 years or older. Wider implications of the findings: DuoStim, which increases the number of acquired eggs, is useful when eggs must be collected as soon as possible. Regarding the clinical pregnancy rate after transplantation, better results were obtained for eggs acquired by the conventional fertility method, but it was necessary to repeat the number of attempts. Trial registration number Not applicable


2021 ◽  
Vol 11 (2) ◽  
pp. 148-164
Author(s):  
Stefano Rossi

The more Victorian physicians deepened their research into female sexuality, the more a culture of lust infected the hypocritical façade of a nation strictly attached to social norms of order, formality, and bigotry. Lascivious sexual desire and carnal appetite – here embodied in female masturbation – were taboos that had to be forcibly silenced. Yet, late-Victorian pornography mocked medical discourses on female onanism, as well as fears related to female sexuality, and revealed ‘unspeakable’ secret domestic settings marred by ‘dangerous’ practices, scandalous carnality and deviant desires. Furthermore, contemptuous of literary censorship and strict morality, the plenteous erotic literature, represented here by William Lazenby's pornographic magazine The Pearl, not only dared to taunt physicians’ concerns about female ‘self-pollution’ circulating at that time, but also found a great inspiration in the huge domestic success of some innovative medical tools – specifically patented to assuage women's nerves – being produced in those years: electric vibrators. Those ‘engines’ rapidly invaded pornographic literature of the late nineteenth century and became central to a great number of erotic stories, titillating fables and poems, as clearly demonstrated by the contents of The Pearl.


1989 ◽  
Vol 34 (9) ◽  
pp. 879-883 ◽  
Author(s):  
Margaret Whitfield

Female sexuality (meaning sexual desire, excitement and orgasm) has been of considerable interest in psychiatry. Women's efforts to define and legitimize their own experience of their sexuality have increased in the past 25 years. However, the integration of these new views into the body of psychiatric (especially psychoanalytic) theory has not occurred very actively or successfully. Very little is known about the development of sexuality in childhood and adolescence. This paper looks at various behaviours, interests and events in women's lives that might reveal something about the development of their sexuality. The literature on female masturbation is reviewed and some sex differences highlighted. The literature on interest in babies, the wish to have babies, and menarche is explored for possible associations with sexuality. Rather than sexuality being a central organizer of experience, it seems quite possible that experience is an organizer of sexuality. Therefore, to better understand female sexuality we need to consider the impact of experiences during childhood and adolescence.


Sexual Health ◽  
2007 ◽  
Vol 4 (4) ◽  
pp. 285
Author(s):  
P. Weerakoon

The female sexual response is highly variable and multifaceted and is a result of interplay of physiological, psychological and interpersonal factors. The advent of technology and non-invasive functional brain imaging has provided a map of the regions of the brain involved in sexual arousal and the neurochemistry that underlies the process. However, this increase in the understanding of the biological basis of female sexuality has only reinforced the role of interpersonal and cultural factor in the sexual response, specially the genesis of sexual desire. An acceptance of this by professionals, has led to the consensus for a more holistic biopsychosocial approach for the management of female sexual concerns. The presentation will discuss the current research on the neural and hormonal basis for female desire and explore the role of sexual desire as a motivator and a force for sexual activity in the context of the prevailing models of the female sexual response. There is a need for the recognition of the place and value of sexual desire in the female sexual response and an appreciation that whereas there is a biological 'drive', this is tempered by the motivational aspect (individual and relationship psychology) and the cultural and moral overlay of values and attitudes. This will in turn provide the milieu for understanding normal and dysfunctional sexual desire and assist us on the road to discovering a best practice model for the diagnosis and management of 'female desire disorders'.


2000 ◽  
Vol 70 ◽  
pp. A131-A131
Author(s):  
I.V. Burets ◽  
A.S. Gasparov ◽  
A.I. Volobuev ◽  
P.A. Basanov ◽  
O.E. Barabanova

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