scholarly journals Thoracic electrical bioimpedance in the follow-up of patients with cardiovascular disorders

2005 ◽  
Vol 133 (5-6) ◽  
pp. 297-302
Author(s):  
Vesna Stojanov ◽  
Mirko Saranovic ◽  
Branko Jakovljevic ◽  
Katarina Paunovic

Thoracic electrical bioimpedance is a new non-invasive technique for obtaining haemodynamic parameters. The method involves the passing of low amperage, high frequency current through the thorax. The current induces a change of resistance within the thorax, which is registered by electrodes. The overall impedance of the thorax is a measure of the electrical resistance of the thorax to this high frequency, low amplitude current. In clinical practice, thoracic electrical bioimpedance has been applied in diagnostic, therapeutic, and prognostic use in patients with heart failure and hypertension, patients with pacemakers, within the scope of early diagnosis of implant rejection following heart transplantation, as well as in patients with kidney disorders, before and after dialysis. However, one of its most important applications is in the determination of antihypertensive therapy, because it provides the parameters that reflect the genesis of arterial blood pressure, in assessing these parameters, optimal therapy adjusted to the haemodynamic status of each patient can be prescribed.

2021 ◽  
Author(s):  
Oya Köksal ◽  
Erdem Haberal

Abstract Purpose Simultaneous monitoring of ECG and thoracic electrical bioimpedance (TEB) is important in evaluating cardiovascular performance. TEB is a non-invasive technique based on measuring the impedance value that changes in the chest area depending on the heartbeat. Within the framework of this study, it can be used in home monitoring and biotelemetry applications to measure thoracic electrical bioimpedance (TEB), ECG and ICG. Methods Within the scope of this study, a four-electrode TEB measurement system was designed and built using the Raspberry Pi single board computer and its original monitor, ESP32 and EVAL-ADAS1000SDZ evaluation board. With the designed system, ECG and thoracic impedance measurements at 50 kHz current frequency were taken as real-time over a single channel. Delta_Z and ICG signals were created from thoracic impedance values with the developed software.ResultsWhile the thoracic impedance value varies between 15-45 Ω, the 67 thoracic impedance value measured with the designed system is approximately 1000 times the 68 reference value. The impedance change in the thoracic region was measured with the designed 69 system between 0.1-0.2 Ω values, and the compatibility of these values with reference values was 70 determined. While the reference value of the dZ / dt signal is 0.8 - 3.5 Ω / s, this value is between 2.3 - 71 5.3 Ω / s in the measurements taken with the designed system.Conclusion The prototype is achieved in detecting small changes in the thoracic impedance signal. The prototype is cheap, portable, small-sized and medically safe, so it is suitable for home care services and clinics. In addition, the developed system can be adapted to wearable technology. In order to increase the success of the system, the impedances values added to the thoracic impedance value should be determined and a calibration procedure should be established.


2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Pauline Reach ◽  
Maxime Touzot ◽  
Yannis Lombardi ◽  
Catherine Maheas ◽  
Emmanuelle Sacco ◽  
...  

Abstract Background and Aims Intradialytic hypotension (IDH) is a common complication in hemodialysis (HD) patients. It is associated with multiple risk factors including cardiac dysfunction and alterations of the peripheral autonomic nervous system. To which extent, dysautonomia may contributed to the occurrence of IHD remains elusive. We sought to investigate the clinical utility of Sudocan®, a device that quantify dysautonomia, in the prediction of IDH. Method We conducted a prospective monocentric study in adult HD patients from July 2019 to February 2020. Dysautonomia was assessed by the measurements of hand and foot Electrochemical Skin Conductance (ESC) by Sudocan®, before and after the end of HD. A pathological hand ESC was defined by an ESC value < 40 μs in Caucasian or < 30 μs in afro-American and Caribbean patients, and a pathological foot ESC by a value < 50 μs in Caucasian or < 30 μs in afro-American and Caribbean patients. Arterial blood pressure (BP) was monitored before, every thirty minutes and after the end of the HD session. The primary end point was the incidence of IDH, according to the NKD/K-DOQI definition, during the 3 month-period study. Results A total of 176 HD patients (64 ±14 years old) were enrolled. Mean pre-dialysis hand and foot ESC were 45±20 μS and 54±22 μS, respectively. Thirty-five and 40% of patients had a pathological ESC at the hand and foot, respectively. Forty-Six IDH occurred during the study period. Logistic regression showed that a pathological hand ESC was associated with an increased risk of IDH [OR=0.39, IC95% (0.15-0.97), p= 0.04]. The cumulative risk incidence of IHD during the study was 2.17 [IC95% (1.21-3.89), p= 0.01] and 1.89 [IC95% (1.06-2.38), p= 0.03], with a pathological hand and foot ESC, respectively. Conclusion A pathological hand ESC, as assessed by a simple, non-invasive test, such as Sudoscan®, is associated with an increased risk of IDH.


1995 ◽  
Vol 89 (2) ◽  
pp. 191-200 ◽  
Author(s):  
C. Cousins ◽  
N. D. Jonker ◽  
L. M. Banks ◽  
S. Mohammadtaghi ◽  
M. J. Myers ◽  
...  

1. The purpose of the study was to evaluate a non-invasive technique for measurement of microvascular permeability to a small hydrophilic solute. 2. The technique measures the clearance of 99mTc-labelled diethylenetriaminepenta-acetic acid (99mTc-DTPA) from plasma into interstitial fluid in a limb after intravenous injection and uses a scintillation probe and a technique of graphical analysis called the Patlak plot, the uptake constant of which reflects 99mTc-DTPA transfer from plasma to interstitial fluid. Using deconvolution analysis, the retention function in the limb of intravenous 99mTc-DTPA was also measured. 3. The clearance values given by these two analytical techniques were compared with clearance from the same vascular bed after bolus femoral intra-arterial injection of 99mTc-DTPA. 4. Sixteen patients undergoing routine diagnostic arteriography were studied: six received sequential femoral intra-arterial injections of 99mTc-labelled human serum albumin (HSA) and 99mTc-DTPA, two received sequential intra-arterial and intravenous injections of 99mTc-HSA and eight received sequential intra-arterial and intravenous injections of 99mTc-DTPA. Tissue uptake and clearance were recorded from the limb with a scintillation probe and plasma clearance by arterial blood sampling. Tracer recirculation was addressed using a second scintillation probe over the contralateral limb. 5. After intra-arterial injection, 99mTc-HSA clearance was monoexponential, reflecting intravascular transit, and was completed by 2–5 min in seven subjects and in about 10 min in one. The corresponding 99mTc-DTPA clearance curves in the six subjects who also received intra-arterial DTPA were biexponential, analysis of which yielded a 99mTc-DTPA extraction fraction of about 0.6. By comparison with 99mTc-HSA clearance, the first exponential clearly corresponded to intravascular transit of unextracted 99mTc-DTPA. 6. In the eight patients given sequential intra-arterial and intravenous injections of 99mTc-DTPA, the second exponential recorded after intra-arterial injection, representing 99mTc-DTPA clearance from the interstitial fluid, agreed well with (a) the Patlak uptake constant recorded over the limb after intravenous injection, representing clearance from plasma into the interstitial fluid and (b) the retention function of 99mTc-DTPA in a limb calculated by deconvolution analysis. The mean clearance following intraarterial injection (expressed in relation to extracellular fluid volume) was 9.6 (SD 2.4) ml min−1 100 ml−1, while the corresponding mean clearance after intravenous injection was 8.8 (2.1) ml min−1 100 ml−1 calculated by Patlak analysis and 10.5 (2.7) ml min−1 100 ml−1 by deconvolution analysis. 7. We conclude that, under the conditions of measurement, 99mTc-DTPA is about 60% extracted into the interstitial fluid in a single pass through an extremity and that clearance into the extravascular space can be measured with reasonable accuracy after intravenous injection.


2016 ◽  
Vol 70 (3) ◽  
pp. 153-157
Author(s):  
Elena Dzikova ◽  
Goran Dimitrov ◽  
Olivera Stojceva-Taneva

Abstract Aims. The prenatal prediction of fetal maturity is very important, since neonatal respiratory distress syndrome (RDS) is one of the biggest causes of neonatal mortality. Our aim was to investigate a new non-invasive method for prediction of fetal maturity and to determine in which group according to gestational age of the fetus, the treatment works the best and in which cases it is necessary to be repeated. Methods. We examined 60 patients (30 with impending preterm delivery, divided in 3 groups: 28-30, 30-32, and 32-34 gestational weeks and 30 controls), at the University Clinic for Gynecology and Obstetrics, Medical Faculty, University “Ss. Cyril and Methodius”, Skopje, R. Macedonia. Fetal maturity was examined using ultrasound histogram from fetal lungs and liver, correlated with gestational age and postpartum RDS. Where possible, we performed amniocentesis for lamellar body count (LBC) to correlate our results with the current invasive method for prediction of fetal maturity. Results. Pre-therapy investigation showed a strong fetal immaturity in 28-32 weeks of gestation and less evident fetal immaturity in 32-34 weeks of gestation. Seventy-two hours post-treatment, fetal maturation was low in the first group, higher in the second and the highest in the third group. Amniocentesis for LBC showed correlation with the ultrasound results. Postpartum results were correlated with pre-delivery ultrasound and showed significance of p <0.05. Conclusion. The results obtained in our study were with high significance, and they were in correlation with other similar studies. However, more extensive investigations should be made to replace the current invasive technique.


2011 ◽  
Vol 5 (4) ◽  
pp. 176
Author(s):  
A. Borlotti ◽  
S. Vermeersch ◽  
E. Rietzschel ◽  
P. Segers ◽  
A.W. Khir

2021 ◽  
Vol 6 (1) ◽  
pp. 33
Author(s):  
Zubaidah Zubaidah ◽  
Insana Maria ◽  
Rusdiana Rusdiana ◽  
Iis Pusparina ◽  
Raihana Norfitri

Introduction: Hypertension is a non-communicable disease that affected on health in the adult age group. Acupressure therapy that can improve blood circulation for people with hypertension. Acupressure therapy can be an alternative treatment option to lower blood pressure and can meet the needs of society in reducing pharmacological therapy. The study was to determine the effect of Acupressure on changes in blood pressure of hypertension sufferers.Method: This study used pre-experimental design. The number of respondents was 15 people with consecutive sampling technique. The research variable is acupressure therapy. While the dependent variable is blood pressure. The data collected are primary data using observation sheets and blood pressure measured with a tensimeter and a stethoscope before and after the intervention. Therapy is done 3 times for 3 three days.Results: The results of the study showed that there was an effect of changes in blood pressure before and after being given acupressure therapy with p = 0.046 and p = 0.003.Conclusion: Acupressure is a simple non-invasive technique that nurses can perform independently. These findings suggest that acupressure can reduce systolic and diastolic blood pressure in patients with hypertension. The further research regarding acupressure therapy for other diseases besides hypertension.


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