scholarly journals Fluconazole in the therapy of Pityriasis versicolor

2005 ◽  
pp. 283-289
Author(s):  
Mirjana Poljacki ◽  
Slobodan Stojanovic ◽  
Sinisa Tasic ◽  
Marina Jovanovic ◽  
Zoran Golusin ◽  
...  
Keyword(s):  
Single Dose ◽  
Clinical Efficacy ◽  
Clinical Examination ◽  
Therapeutic Efficacy ◽  
Pityriasis Versicolor ◽  
Mycological Examination ◽  
Clinical Healing ◽  
Systemic Application ◽  
Diagnosis Of Diseases

The authors present the results of the systemic application of flukonazole in therapy of Pityriasis versicolor. It was arranged for the total number of 38 patients, 18 females and 20 males. The diagnosis of diseases was established on the base of the clinical examination, the native mycological examination and by the using of Wood lamps. The therapy was passed by the using of 300 mg flukonazole in a single dose, once weekly, during two weeks. The following period amounted to one week after the passed therapy. The therapeutic efficacy was assessed with regard to the clinical and mycological healing. The clinical efficacy was assessed semiquantitative on the base of increasing of the percentage rates of the total score of disease that was computed by collecting of the numeric values for every clinical argument typical for the disease, and the mycological efficacy on the base of the mycological findings and the fluorescence finding after lightening with the Wood's lamp. The controlling examinations were performed on day 0, 14 and 22. The results of investigations have shown that the complete clinical healing was achieved after two weeks of therapy in 94,74%, and the mycological healing in 92,11% patients. The rate of the mycological healing was evaluated after 1 week of following period equal to the rate of the clinical healing and it was also 94,74%. The undesirable effects of the drug applications weren't by any patient.

scholarly journals Therapeutic efficacy of topical luliconazole versus topical ketoconazole in the treatment of pityriasis versicolor patients: a hospital based comparative study

2020 ◽  
Vol 6 (2) ◽  
pp. 248
Author(s):  
Shahid Hassan ◽  
Ashutosh Ranjan
Keyword(s):  
Comparative Study ◽  
Clinical Efficacy ◽  
Therapeutic Efficacy ◽  
Skin Lesions ◽  
Similar Efficacy ◽  
Pityriasis Versicolor ◽  
Male Population ◽  
Treatment Regimens ◽  
Mycological Examination

<p class="abstract"><strong>Background:</strong> To evaluate the clinical efficacy of 1% topical luliconazole versus 2% topical ketoconazole in pityriasis versicolor patients.</p><p class="abstract"><strong>Methods:</strong> Mycological examination of all the pityriasis versicolor patient was done by using skin scrapings were collected from the skin lesions to prepare for 10% KOH mount, which was examined under the microscope to note the findings as KOH mount positive or negative for Malassezia fungi. KOH mount positive or negative was noted at 0 days, 2 weeks and 4 weeks continued treatments with luliconazole and ketoconazole.<strong></strong></p><p class="abstract"><strong>Results:</strong> At the first days, majorities of patients 46 (92%) of luliconazole group were positive for KOH mount. At 14 days treatment with luliconazole, patients had 11 (22%) positive for KOH mount. At the 28 days treatment with luliconazole, only 2 (4%) patients were positive and most of the patients 49 (98%) were negative for KOH mount. Similarly, in ketoconazole group patients, 47 (94%) patients were positive for KOH mount in beginning of treatment. At 14 days treatment with ketoconazole 16 (32%) patients were positive and 34 (68%) patients were negative for KOH mount. And at the 28 days with treatment of ketoconazole 13 (26%) patients were positive and most of the patients 37 (74%) were negative for ketoconazole.</p><p><strong>Conclusions:</strong> Male population as well as age 26-35 years were more prone for pityriasis versicolor infection. On two weeks of treatment luliconazole and ketoconazole had near about similar efficacy against pityriasis versicolor. But, on continue 4 weeks of treatment regimens topical luliconazole had more clinically efficacious than ketoconazole against pityriasis versicolor.</p>

scholarly journals SIXTEEN YEARS OF PITYRIASIS VERSICOLOR IN METROPOLITAN AREA OF PORTO ALEGRE, SOUTHERN BRAZIL

2015 ◽  
Vol 57 (4) ◽  
pp. 277-280 ◽  
Author(s):  
Daiane HEIDRICH ◽  
Tatiane Caroline DABOIT ◽  
Cheila Denise Ottonelli STOPIGLIA ◽  
Cibele Massotti MAGAGNIN ◽  
Gerson VETORATTO ◽  
...  
Keyword(s):  
Metropolitan Area ◽  
Black People ◽  
Epidemiological Studies ◽  
Pityriasis Versicolor ◽  
Angular Coefficient ◽  
Porto Alegre ◽  
Younger Age ◽  
Reference Hospital ◽  
Mycological Examination

SUMMARY Pityriasis versicolor is the most common of the diseases caused by Malasseziayeasts. The aim of this study is to determine the prevalence of pityriasis versicolor and its etiological aspects in the metropolitan area of Porto Alegre, Brazil. A retrospective crosssectional study with data from patients of a reference hospital from 1996 to 2011 was performed. Collected data included: date, age, gender, ethnicity, anatomical region of lesion and the direct mycological examination results. Among the positive results in the direct mycological examination, 5.8% (2,239) were positive for pityriasis versicolor. The angular coefficient (B) was -0.3%/year, showing a decrease over the years. The disease was more prevalent in men (7.1% of men versus 5.1% of women that underwent the direct mycological examination); younger age (median 31 years old); "pardo" and black people (3.7% more than expected in the sample); trunk (73.44% of the affected anatomic sites). Lesions in rare sites (groin, genitals, legs, feet and hands) were also observed in this study. In conclusion, due to the decrease in the prevalence of pityriasis versicolor, long-term epidemiological studies in the metropolitan area of Porto Alegre, Brazil, are needed to continue the monitoring of this disease.

scholarly journals The study of the effectiveness of the spray Fungin Forte in the treatment of dermatophytosis in cats

2019 ◽  
Vol 2019 (3) ◽  
pp. 30-34
Author(s):  
Лидия Куприянова ◽  
Lidiya Kupriyanova ◽  
Евгения Багринцева ◽  
Evgeniya Bagrinceva ◽  
Ольга Петрова ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Therapeutic Efficacy ◽  
Hair Growth ◽  
Skin Lesions ◽  
Local Processing ◽  
Point Scale ◽  
Complex Therapy ◽  
Oral Form

This article presents a study of the effectiveness of the spray Fungin Forte (developed by LLC API-SAN) in the complex therapy of dermatophytosis in cats on a group of 20 animals infected spontaneously. Terbinafine in oral form in tablets was used as a fungicidal preparation and Fungin Forte samples in the form of a spray were used for local processing. The criteria for clinical efficacy were the results of an examination with a planimetry, which noted a reduction and change in the affected skin lesions, a decrease in the degree of itching (using a standard 10-point scale to assess itching), erythema, peeling, hair growth, and a negative mycological study conducted on DTM environment. The total therapeutic efficacy by the thirtieth day was 95 %, which allows the use of the spray as a local fungicide.

Clinical Efficacy and Tolerability of Terbinafine 1% Cream in Patients with Pityriasis Versicolor

1996 ◽  
Vol 8 (3) ◽  
pp. 169
Author(s):  
Ho Sun Jang ◽  
Hyun Tae Lee ◽  
Cheon Gi Kim ◽  
Kyung Sool Kwon ◽  
Tae Ahn Chung
Keyword(s):  
Clinical Efficacy ◽  
Pityriasis Versicolor

Clinical Efficacy of A Single Dose Radioiodine Therapy for Hyperthyroidism

2015 ◽  
Vol 1 (1) ◽  
pp. 13
Author(s):  
Zabah Muhammed Jawa ◽  
Rufai Isa Ahmed ◽  
Aisha Ismail
Keyword(s):  
Single Dose ◽  
Clinical Efficacy ◽  
Radioactive Iodine ◽  
Radioiodine Therapy ◽  
Antithyroid Drug ◽  
Radioactive Iodine Therapy ◽  
Toxic Adenoma ◽  
Plummer's Disease ◽  
Plummer’S Disease ◽  
Post Therapy

<p><strong>Objective</strong>: Radioiodine is a safe, cheap, and recognized permanent treatment option for patients with hyperthyroidism. Despite, the extensive use of radioiodine therapy in hyperthyroidism there is no consensus regarding the optimal dose of radioiodine. To evaluate the clinical efficacy and our clinical experience with the use of a single dose radioiodine therapy for hyperthyroidism in our institution.</p><p><strong>Methods:</strong> A total of 274 patients who received a single dose of radioactive iodine therapy for hyperthyroidism at our institution between 2007-2015 were retrospectively reviewed. Of these, 186 patients had Graves’ disease (GD), 73 patients had Plummer’s disease (PD), and 15 patients had a single toxic adenoma (STA). All patients received between 10-30mCi of oral radioiodine capsule. The efficacy of therapy was determined 3 months post-therapy using serum thyroid function test, weight and heart rate measurements. Therapy success refers to patients whose outcome was euthyroidism and hypothyroidism post-therapy and treatment failure where patients still manifested with persistent hyperthyroidism.</p><p><strong>Results:</strong>  The efficacy of a single dose of radioiodine 3months post-therapy varies with the type of hyperthyroidism, 96% for Graves’s disease, 92% for Plummer’s disease and 100% in single toxic adenoma.</p><p><strong>Conclusion:</strong> Our study showed that a single dose of radioactive iodine therapy 3 months post-therapy is 96% efficient in all types of hyperthyroidism. However, we observed that patients at risk of therapy failure 3month post-therapy included, large thyroid gland prolong antithyroid drug usage and male gender.</p><p> </p>

Clinical Efficacy of Treatment of Children with Bronchial Asthma, Population in Remote Areas in Terms of Regional Respiratory Centre as Sanatorium Type: Work Results for 10 Years

10.12737/7279 ◽  
2014 ◽  
Vol 21 (4) ◽  
pp. 102-108
Author(s):  
Ермакова ◽  
I. Ermakova
Keyword(s):  
Bronchial Asthma ◽  
Clinical Efficacy ◽  
Clinical Examination ◽  
Main Group ◽  
Remote Areas ◽  
Number Of Children ◽  
Children With Asthma ◽  
Respiratory Centre ◽  
Severe Degree ◽  
Efficacy Of Treatment

The purpose of this work is to improve the specialized medical care for children with bronchial asthma, people living in remote areas and villages. Materials and methods: The study involved 1,024 children with asthma (solid sample, 2003) which were observed in period of 2003 to 2013. There are 391 children-villagers as the main group; clinical examination was carried out by district pediatrician and 633 children as regional city residents (the comparison group); clinical examination was carried out by district pediatrician together with pulmonologist or allergist. The author used the methods of observation (solid documentary and selective, current, prospective) and the method of expert evaluations. Results: a significant discrepancy (p=0,03) in the evaluation by district pediatrician, practitioner or family doctor) of severity bronchial asthma and absence of bronchial asthma treatment in 28% of patients of the main group has been demonstrated in 2003. The discrepancy in the diagnosis of bronchial asthma of light degree and medium severe degree (p=0.03) were detected by a positively accepted method (examination of pulmonologist/allergist, clinical and instrumental examination, 2008). Clinical efficacy of treatment of children with bronchial asthma as residents in regional respiratory centre has been proven. For ten years the number of children with BA decreased by 25%, the number of bronchial asthma patients with moderate current (p=0.03) decreased and the number of patients with medium severe degree bronchial asthma (p=0.01) significantly increased. In 2013, the patients of the main group observations received adequate basic therapy bronchial asthma; number of children with asthma decreased in 2 times (p=0.03); the calls in the ambulance and the need for hospitalization decreased more than 2 times (p=0.03); the number of children with controlled bronchial asthma increased from 26 to 64% (p=0.05).

scholarly journals Efficacy of albendazole in giardiasis

2001 ◽  
Vol 7 (4-5) ◽  
pp. 787-790
Author(s):  
R. Baqai
Keyword(s):  
Single Dose ◽  
Clinical Examination ◽  
Divided Dose ◽  
Response To Therapy ◽  
Faecal Samples ◽  
Helminthic Infection ◽  
Protozoal Infection

Albendazole and metronidazole were compared in 68 patients diagnosed positive for giardiasis. Albendazole 1200 mg, one dose was given to 24 patients, albendazole 400 mg twice a day for 3 days was given to 23 patients, and metronidazole 400 mg 3 times a day for 5 days to 21 patients. Response to therapy was monitored by clinical examination and analysis of fresh faecal samples on days 0, 3, 7 and 10. Response to the single dose of albendazole was 55%, to the divided dose of albendazole 70%, and to metronidazole 84%. The results show that albendazole, originally recommended for helminthic infection, can also be used in patients with mixed protozoal infection or for infections resistant to metronidazole.

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