scholarly journals History of Repeated Bleeding from Intact Skin and Mucous Membranes: A Quiz

Author(s):  
Saskia Wortmann ◽  
Tobias Welponer ◽  
Martin Laimer

Abstract is missing (Quiz)

Author(s):  
L. V. Lukovnikova ◽  
G. I. Sidorin

The article presents the results of a study of the toxicity of fire-resistant turbine oil «Turbomas «, a derivative of diphenyl-(n-tert-butylphenyl phosphate). According to toxicity parameters, «Turbomas» oil is characterized as a low-toxic compound, does not have neuroparalytic action, exhibits mild cumulative properties, does not irritate the skin and mucous membranes, penetrates intact skin,


Author(s):  
Sami Hoshi ◽  

A 58-year-old man presented with 4-day history of multiple, erythematous, non-itchy, painless, patchy spots, along with fatigue and jaw pain. This rash started around the periumbilical area and then spread over his chest and right upper back (Figure 1,2). There was no involvement of face, mucous membranes, and extremities. He denied any sore throat, cough, or other symptoms. Besides the skin rash, his physical examination was unremarkable. There was no temporomandibular joint swelling, or joint tenderness. A month ago, he travelled along with the west coast of Michigan – a Lyme-endemic region of the USA and noted his exposure to mosquitoes. Shortly after his visit, he recalled having fever, chills, myalgia and a similar patchy groin rash which resolved in a few days. At that time, blood work by his family physician revealed mild transaminitis. At the current visit, repeat blood work and electrocardiogram were normal. A clinical diagnosis of early disseminated Lyme disease was made. Lyme Ab IgM and IgG were both elevated, as was his Western blot test. He was given a 10-day course of doxycycline. He reported complete resolution of his symptoms at follow up.


2020 ◽  
Vol 92 (10) ◽  
pp. 88-96
Author(s):  
E. A. Troshina ◽  
V. A. Volnukhin ◽  
V. A. Petrov ◽  
N. F. Nuralieva ◽  
M. Yu. Yukina ◽  
...  

Vitiligo is a common polygenic autoimmune disease in which the foci of depigmentation are formed on the skin and/or mucous membranes as a result of the death of melanocytes. There are several hypotheses for the pathogenesis of the disease, the leading role among them is played the autoimmune hypothesis. This review summarizes the available literature data on the prevalence and structure of comorbid endocrine autoimmune pathology in vitiligo patients. In most studies conducted in Europe, America and Asia the prevalence of autoimmune thyroid diseases (including autoimmune thyroiditis and Graves disease), diabetes mellitus and autoimmune adrenal insufficiency was higher in vitiligo patients than in the general population. The results of some studies indicate a frequent association of vitiligo with autoimmune polyglandular syndromes. In the structure of comorbid pathology the highest prevalence was in autoimmune thyroid diseases. A number of studies have established a higher prevalence of autoimmune endocrine diseases in women, as well as in nonsegmental vitiligo patients and in cases of family history of vitiligo and/or other autoimmune diseases. In addition, it was shown that the prevalence of endocrine diseases increases with increasing area of depigmentation. The data obtained justify the advisability of conducting a timely examination of vitiligo patients with the aim of early detection of comorbid diseases and the appointment of appropriate treatment. Further studies are needed to investigate the effect of the identified associations on the course of vitiligo and comorbid endocrinopathies, as well as the effectiveness of therapy and the quality of life of patients.


2017 ◽  
Vol 69 (3) ◽  
pp. 623-626
Author(s):  
M.O. Firmino ◽  
M.T.S. Frade ◽  
R.C. Alves ◽  
L.Â. Maia ◽  
R.G. Olinda ◽  
...  

ABSTRACT We report a case of intestinal intussusception secondary to enteritis caused by Pythium insidiosum infection in a 1-year-old mixed breed bitch that died after a 30-day history of bloody diarrhea, anorexia, weight loss, listlessness, dehydration, and pale mucous membranes. Necropsy revealed two areas of intussusception, one jejunum-jejunal and one ileum-cecum-colic. The first intussusception showed slight congestion of the intestinal loop, which was resolved by manual traction, while the second intussusception exhibited thickening, irregular yellow spots, and transmural congestion. Histologically, the jejunum-jejunal segment had ischemic lesions secondary and ileum-cecum-colic intussusception there was also necrotizing, pyogranulomatous enteritis associated with negative images of intralesional fungal hyphae that were well visualized by silver impregnation. Immunohistochemistry identified the hyphae as Pythium insidiosum. The diagnosis was made based on the histological changes and confirmed by immunohistochemistry. We can conclude that enteritis by P. insidiosum in dogs can occasionally cause intestinal intussusception and result in acute death.


2015 ◽  
Vol 23 (2) ◽  
pp. 81-83
Author(s):  
Mukulika Saha ◽  
Amit Chakrabarti ◽  
Amit Bikram Maity ◽  
Satadal Mandal

IntroductionIngested foreign bodies commonly get impacted in the upper aero digestive tract, but only a few of these foreign bodies have perforated the oesophagus and an even smaller number of these have migrated extraluminally. Case reportA 43 year old male patient presented with history of accidental ingestion of fish bone (F.B) 3 weeks back. On examination a sharp pointed swelling was seen over right side of neck and on palpation a pointed object was felt beneath the intact skin. Digital X-ray, ultrasonography of the neck and CT scan neck showed a linear obliquely placed foreign body on right side of neck at the level of thyroid gland. The foreign body was easily removed by an incision over the skin and was confirmed to be a fish bone. DiscussionHorizontally oriented foreign bodies are more likely to penetrate the lumen of a hollow viscus. The muscular contraction of the neck might account for this unusual event to some extent, one possible factor being that the presence of the foreign body in the soft tissue might have led to inflammation and oedema, which made the texture of the surrounding tissue loose and lax ; a sort of gel-sol interconversion. 


1993 ◽  
Vol 74 (6) ◽  
pp. 417-419
Author(s):  
V. V. Morozov ◽  
M. Z. Minniyarova

The production of organic peroxides at the Kazan Production Association Orgsintez was commissioned in 1970 under the project of Constructors John Brown (England). This is a large complex, which includes over 30 detached pavilion-type buildings. The layout of the premises in the production buildings is made in accordance with the existing sanitary and fire safety standards. Organic peroxides are used as initiators of polymerization, oxidizing agents, for the synthesis of dehydropolymers, epoxy derivatives, as bleaching materials. They have a local effect on the skin, mucous membranes of the eyes, upper and lower respiratory tract, penetrate through intact skin. Some of them affect the central nervous system. Their distinctive feature is the ability to induce methemoglobin formation. The mechanism of action of organic peroxides is due to their ability to oxidize a number of enzymes containing a thiol group. They are capable of causing hemolysis and inhibiting the activity of sulfhydrol enzymes.


2019 ◽  
Vol 7 (3) ◽  
pp. e000774
Author(s):  
Matthew Levinson ◽  
Allison Kirby ◽  
Austin Richman ◽  
Melissa Hall

A 3-year-old, 29.5 kg female, spayed, labrador retriever cross with a 5-month history of severe, persistent papillomas affecting the oral mucous membranes was successfully treated using a multimodal approach that included staged aggressive cryotherapy. On presentation, verrucous growths varying in sizes of 2 mm–3 cm were appreciated affecting all tissues of the oral cavity. There were two alopecic, pedunculated growths with frond-like projections approximately 4 mm by 4 mm and 1 cm by 4 mm on the left pelvic paw. While the growths on the paws resolved with minimal intervention, the oral verrucous growths remained. A combination of interferon alpha-2B, canine papillomavirus-1 autologous vaccine, surgical excision, carbon dioxide laser ablation and aggressive cryotherapy led to complete resolution and continued remission of the canine oral viral papillomas.


2021 ◽  
Vol 5 (2) ◽  
pp. 26-32
Author(s):  
Putu Ayu Adindhya Saraswati Surya ◽  
Ni Nyoman Sunariasih

Background: Stevens Johnson syndrome (SJS) is a collection of acute and life threatening skin symptoms caused by an allergic drug reaction. SJS also attacks the other mucous membranes, one of which is the eye. SJS is a rare case. The initial complaint of SJS is the eruption on the skin in the form of redness followed by blisters and attacking other mucous membranes. The ocular manifestations of SJS are conjunctivitis, corneal erosion, corneal ulcers, and blepharitis. Methods: Treatment of SJS’s ocular manifestation is administration of drugs and surgical intervention. Administration of drugs that often done in the acute phase is antibiotic eye drops with steroids to prevent complications. Complications that can occur include symblepharon, districhiasis, and keratitis. This complication can cause a sharp decrease in vision. Results: This case report discusses a 68 year old male patient with blisters all over his body accompanied by swelling in both eyes, redness in both eyes, and difficult to open eyes. Patients with history of taking the new drug a month ago. No history of drug allergy. The patient suffered from hypertension, non-hemorrhagic stroke, and epilepsy with irregular treatment. Patient was performed a fluorescein test. In this case, the patient is given antibiotic ointment and artificial tears with steroids. In this case there were no complications. Conclusion: The ocular manifestations of SJS if handled quickly and properly can prevent long-term complications.


Author(s):  
Akhmedov Shavkat Kurbonalievich ◽  
◽  
Ashirov Zohijon Fayozjonovich ◽  
Oripov Rustam Anvarovich ◽  
Siddikov Olim Abdullaevich ◽  
...  

Urticaria is an allergic disease characterized by the appearance of blisters on the skin and mucous membranes. The disease can be caused by external factors (temperature, mechanical, chemical) or internal (diseases of internal organs, disorders of the nervous system). [1, 2]. Allergies can be caused by toxins, bacteria, and undigested food. In the diagnosis of the disease, anamnestic data, dermography and various skin allergological tests are used. There are acute (up to 6 weeks) and chronic (more than 6 weeks) urticaria. The latter is characterized by daily or frequent symptoms (blistering, itching, angioedema for 6 weeks or more [3, 4]. During life, 0.5-1% of the entire population of people suffers from chronic urticaria. At the same time, if acute urticaria is usually associated with the action of exogenous factors and allergens (food, medicines, insect bites, etc).


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