A rare case of multiple myeloma with extramedullary localizations: diagnosis and follow-up by computed tomography

2019 ◽  
Vol 6 (3) ◽  
Author(s):  
Anna Rotundo ◽  
Valentina Settino ◽  
Domenico Laganà
2019 ◽  
Vol 103 (9-10) ◽  
pp. 461-467
Author(s):  
Seiji Natsume ◽  
Yoshiki Senda ◽  
Tsuyoshi Sano ◽  
Seiji Ito ◽  
Koji Komori ◽  
...  

There have been no reports of ruptured solid pseudopapillary neoplasm (SPN) into adjacent organs. A 22-year-old female was referred to our hospital for treatment of a pancreatic head tumor. Computed tomography (CT) examination at our hospital showed a 5-cm tumor containing air, although CT at a previous hospital revealed an 8-cm tumor without air. Thus, a spontaneous rupture of the tumor into the duodenum was suspected. Subtotal stomach preserving pancreaticoduodenectomy with combined resection of the portal vein was performed. Contrast radiography of resected specimen showed the medium injected into the tumor leaking out from the 2nd portion of the duodenum. Histologically, the patient was diagnosed as SPN. Microscopic invasion to the portal vein and duodenum were also confirmed. She did not experience any postoperative complications and has remained well without any signs of recurrence during 2 years of follow-up. Although there have been 14 studies reporting ruptured SPN, this is the first report of SPN that spontaneously ruptured into the duodenum. An extremely rare case of SPN of the pancreatic head that spontaneously ruptured into the duodenum was reported.


2017 ◽  
Vol 2 (2) ◽  
pp. 1-15 ◽  
Author(s):  
Juliana Maria de Almeida Vital ◽  
Terence Pires de Farias ◽  
Fernando Luiz Dias ◽  
Juliana Fernandes de Oliveira ◽  
José Gabriel Miranda da Paixão ◽  
...  

Paragangliomas can be found from the skull base to the sacrum. Sinonasal paragangliomas are infrequent. A 16-year-old female reported spontaneous discrete bilateral epistaxis once a month beginning when she was 3 years of age. Computed tomography showed an expansive hypervascular mass occupying the right nasal cavity and nasopharynx. Sinonasal paragangliomas usually occur in middle-aged women. Radiologic investigation is essential for the diagnosis of sinonasal paragangliomas and evaluating extension of the lesion. Endoscopic and conventional approaches are effective, and preoperative embolization is paramount for reducing bleeding risk. Histopathological features cannot differentiate benign from malignant paragangliomas, and since metastasis may eventually occur, follow-up must be carried out for a long period of time.


2020 ◽  
Vol 30 (6) ◽  
pp. 3198-3209
Author(s):  
M. M. Sieren ◽  
F. Brenne ◽  
A. Hering ◽  
H. Kienapfel ◽  
N. Gebauer ◽  
...  

Author(s):  
Aleksander Kosmala ◽  
Thorsten Bley ◽  
Bernhard Petritsch

Background Multiple myeloma is a malignant hematological disease characterized by uncontrolled proliferation of monoclonal plasma cells mainly in the bone marrow. Imaging plays a crucial role in diagnosis and follow-up. Method This literature review provides information about multiple myeloma, its precursor diseases, and available imaging techniques. Advantages and limitations as well as possible prognostic and therapeutic implications of the different imaging methods are presented in the context of the current literature. Results and Conclusion Cross-sectional imaging has replaced conventional X-ray skeletal survey. Widely available whole-body computed tomography is routinely used to detect osteolytic lesions. Magnetic resonance imaging is the most sensitive technique to identify bone marrow infiltration and is recommended in multiple myeloma precursor diseases. Positron emission computed tomography combines morphological and functional imaging. It is mainly used for follow-up, therapy monitoring, and response evaluation. Key points:  Citation Format


2015 ◽  
Vol 100 (5) ◽  
pp. 958-961
Author(s):  
Linli Tian ◽  
Jiarui Zhang ◽  
Yufei Jiao ◽  
Tianyi Liu ◽  
Ming Liu

Hemangiomas rarely occur in the retropharyngeal space with only several cases reported in the current literature. This article reports the hemangiomas of retropharyngeal space. A 55-year-old woman was referred to our institution for dysphagia. Computed tomography and magnetic resonance imaging of the neck and spine revealed a large, well-circumscribed, dense mass that extended from the retropharyngeal space to the sides of the neck. Patient underwent direct excision of the lesion. Complete regression of symptoms was observed after surgery, with no lesions found on routine 24-month follow-up. Although hemangiomas are relatively common in the head and neck, those that originate in the retropharyngeal space are very rarely observed. These benign tumors have the potential to compress adjacent tissues or organs and thereby produce associated symptoms like dysphagia and dyspnea. We present the reported case of larger hemangiomas of the retropharyngeal space and detail their management.


2021 ◽  
pp. 153857442110040
Author(s):  
Luis H. Arzola ◽  
Javier E. Anaya-Ayala ◽  
Gabriel Lopez-Pena ◽  
Lizeth Luna ◽  
Christopher Ruben-Castillo ◽  
...  

Primary aortitis (PA) secondary to Listeria monocytogenes is extremely rare with only a few cases reported in the literature. Presently, there is no consensus concerning the best treatment when no complications are found in the thoracic computed tomography (CT) imaging. This report illustrates the clinical presentation and favorable clinical course of a rare case of PA secondary to Listeria monocytogenes in an 82-year-old diabetic woman, successfully treated with conservative management with 18 months of follow up. Included in this article, we additionally present a review of the literature of this uncommon etiology of infectious aortitis.


2019 ◽  
Vol 22 (3) ◽  
pp. E252-E255
Author(s):  
Runqian Sui ◽  
Jie Zi ◽  
Liangong Sun ◽  
Decai Li ◽  
Anbiao Wang

Anastomotic pseudoaneurysm remains one of the main life-threatening complications of cardiac and thoracic aorta surgery. We report a rare case of infected pseudoaneurysm at the anastomotic line found during follow-up. Blood culture results suggested Enterococcus faecium infection. Transthoracic echocardiography and computed tomography scans revealed the presence of a pseudoaneurysm of the ascending aorta. The pseudoaneurysm was resected and the ascending aorta was reconstructed with an artificial vascular patch without complications. Reducing the anastomotic tension, with complete hemostasis at the anastomotic incision, is the most important means of preventing the formation of pseudoaneurysm.


2020 ◽  
pp. 1-2
Author(s):  
Arpita Mishra

Introduction: Multiple Myeloma (MM) constitutes for 10% of all haematological malignancies and 1% of all malignancies. They cover a wide spectrum of diseases from the premalignant condition Monoclonal Gammopathy of Undetermined Significance(MGUS) to symptomatic Multiple Myeloma, Malignant Lymphomas, and Chronic Lymphocytic Leukaemia (CLL).Objective: Presenting a case report of a rare case of Multiple Myeloma which does not quite well fit into the said subclassifications. Result: Serum free light chain ratio is normal with M spike. Conclusion: A patient presenting with clinical features of multiple myeloma should undergo extensive work up for not only correct diagnosis but also for follow up.


2015 ◽  
Vol 8 (3) ◽  
pp. 509-514 ◽  
Author(s):  
Sakiko Mizuno ◽  
Ukei Anazawa ◽  
Hiraku Hotta ◽  
Naofumi Asano ◽  
Michiro Susa ◽  
...  

Osteoid osteoma (OO) usually occurs in the extremities of young adults. The tumor can arise in any part of the skeletal tissue; however, it is rarely found in the rib, with limited reports to date. In this report, we present a rare case of OO arising in the rib, which was successfully treated under computed tomography guidance with minimal invasiveness. At the final follow-up after 4 years, no local recurrence was observed.


2010 ◽  
Vol 55 (No. 5) ◽  
pp. 253-257 ◽  
Author(s):  
S. Park ◽  
J. Park ◽  
JM Kim ◽  
JH Kim ◽  
J. Son ◽  
...  

A ten-month old, male Black and Tan Coonhound dog was referred with ocular bleeding due to gunshot injury. His mental state was normal. A computed tomography revealed that the bullet was planted in the left cranium. It was presumed that the trajectory of the bullet penetrated from the right medial angle of the eye to the orbit, and changed its track to caudo-dorsal by penetrating the cranium, ending up at the left cranium. The bullet was removed by lateral rostrotentorial craniectomy. No complications were observed during a one-year follow-up except the blindness in the right eye. This is a rare case of gunshot-induced traumatic brain injury featuring a bullet which went through the orbit into the cranium. The damaged frontal lobe seemed to show no neurological signs at the time of first examination in this case. In conclusion, a less aggressive surgical approach is recommended to remove bullets when they are accessible.


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