scholarly journals Repairing the ‘Broken Middle’ of the Health Innovation Pathway

2013 ◽  
Vol 26 (3) ◽  
pp. 103-123 ◽  
Author(s):  
James Mittra

The emergence of Translational Medicine (TM) as a potential solution to health innovation challenges has gained currency in scientific, clinical and policy discourses. Using interview data from key professionals involved in TM, this article explores diverse practitioner definitions and the multiple meanings ascribed to TM in the context of a purportedly broken R&D system and promissory visions and expectations built around new life science. It also begins to address some of the transformative impacts of TM on the broader institutional landscape for life science innovation, particularly the changes in traditional institutional boundaries. I conclude that in light of the multiple framings of TM, it might best be conceived as an institutional mechanism or process for co-ordinating multiple actors and complex activities in the new collaborative research and development contexts now demanded of the life sciences.

2002 ◽  
Vol 15 (1) ◽  
pp. 3-28
Author(s):  
Jason Owen-Smith ◽  
Walter W.Powell

Drawing on interviews with more than 80 scientists on two university campuses, we create a typology that offers insights into how transformations in the nature and locus of life science innovation influence academic careers and work practices. Our analyses suggest that a strong outcome of increased academic concern with research commercialisation is the appearance of new fault lines among faculty, between faculty and students, and even between scientists’ interests and those of their institutions. We argue that life science commercialisation is driven by a mix of new funding opportunities, changing institutional mandates for universities, and novel research technologies that bring basic research and product development into much closer contact. The rise of patenting and commercially motivated technology transfer on U.S. campuses stands to alter faculty work practices and relationships, while transforming the criteria by which success is determined and rewards are allocated. Through close analysis of interviews with four researchers who typify a range of academic responses to commercialism, we demonstrate emerging patterns of conflict and agreement in faculty responses to commercial opportunities in the life sciences.


2011 ◽  
Vol 8 (2) ◽  
pp. 49-58 ◽  
Author(s):  
Can Türker ◽  
Fuat Akal ◽  
Ralph Schlapbach

Summary In this demo paper, we sketch B-Fabric, an all-in-one solution for management of life sciences data. B-Fabric has two major purposes. First, it is a system for the integrated management of experimental data and scientific annotations. Second, it is a system infrastructure supporting on-the fly coupling of user applications, and thus serving as extensible platform for fast-paced, cutting-edge, collaborative research.


2010 ◽  
Vol 9 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Lena A.E. Tibell ◽  
Carl-Johan Rundgren

Molecular life science is one of the fastest-growing fields of scientific and technical innovation, and biotechnology has profound effects on many aspects of daily life—often with deep, ethical dimensions. At the same time, the content is inherently complex, highly abstract, and deeply rooted in diverse disciplines ranging from “pure sciences,” such as math, chemistry, and physics, through “applied sciences,” such as medicine and agriculture, to subjects that are traditionally within the remit of humanities, notably philosophy and ethics. Together, these features pose diverse, important, and exciting challenges for tomorrow's teachers and educational establishments. With backgrounds in molecular life science research and secondary life science teaching, we (Tibell and Rundgren, respectively) bring different experiences, perspectives, concerns, and awareness of these issues. Taking the nature of the discipline as a starting point, we highlight important facets of molecular life science that are both characteristic of the domain and challenging for learning and education. Of these challenges, we focus most detail on content, reasoning difficulties, and communication issues. We also discuss implications for education research and teaching in the molecular life sciences.


2004 ◽  
Vol 820 ◽  
Author(s):  
Martina Daub ◽  
Rolf M. Kaack ◽  
Oliver Gutmann ◽  
Chris P. Steinert ◽  
Remigius Niekrawietz ◽  
...  

AbstractFor the performance of certain analytical and diagnostic tasks in modern Life Science applications high throughput screening (HTS) methods are essential. Miniaturization, parallelization and automation allow to decrease consumption of expensive materials and lead to faster analyzing times. The miniaturization of total assay volumes by the use of microtiter plates as well as the microarray technology have revolutionized the field of biotechnology and Life Sciences. Neither printing of microarrays with droplet volumes of several picoliters, nor handling of precious enzymes in the upper nanoliter range can be accomplished with traditional liquid handling devices like air displacement pipettes. The development of novel low volume liquid handling devices, which are subject to current research, addresses the diverse requirements shifting steadily to lower volumes. Various novel non-contact dispensing methods in the nanoliter and picoliter range are presented and classified according to their working principles like air displacement and direct displacement methods (TopSpot®, NanoJetTM, Dispensing Well PlateTM). Properties of the various methods are compared in terms of flexibility, integration density, speed of operation, precision, addressable volume range and amenability to multi-parallel operation.


2021 ◽  
pp. 002205742110268
Author(s):  
Joel I. Cohen

Naturalists enrich our scientific understanding of biodiversity. However, just as countries have fallen behind on commitments to provide biodiversity conservation funding, so has the focus of life science stayed arm’s length. The purpose of this article is to consider why biodiversity should be the center of life sciences education and how biographies of Charles Darwin and the incorporation of female scientists allow important findings, paintings, and journaling as part of standard teachings. The addition of female naturalists will provide role models for diverse, underrepresented student populations. This article suggests that biodiversity and biography become central to hteaching life sciences while supplemented by other practices. Such reallocations provide students an opportunity to learn not only what these scientists discovered but how these individuals “developed” into scientists.


2015 ◽  
pp. 207-228
Author(s):  
Alexander Styhre

1982 ◽  
Vol 1 (1) ◽  
pp. 5-16 ◽  
Author(s):  
Samuel M. Hines

Although we may be pessimistic (with good reason) about contemporary politics, especially as it effects the prospects for the survival of the human species in the long run, we can be more optimistic about the study of politics from a life science perspective. Certainly the two are related. Becoming optimistic about the former may depend in part upon the further development of biopolitics and of the biobehaviorial and life sciences generally.


2019 ◽  
Vol 34 (7) ◽  
pp. 1271-1271
Author(s):  
H Patino-Carvajal ◽  
L Tibiriçá ◽  
Y Garcia ◽  
A Maresco ◽  
I Tourgeman

Abstract Objective The purpose of this study was to investigate the prevalence of Emotional Intelligence (EI) research among 19 Latin American countries. Participants and Method Respective to each country, Total Life Science publications and Psychology publications were gathered from “UNESCO Science Report Towards 2030.” Population and GDP statistics pertaining to each country were derived from CIA Factbook. Mean education and percentage of GDP allocated for education were gathered from UNESCO Institute for Statistics. The databases SciELO and Redalyc were used to exhume the number of published Emotional Intelligence articles. The term “inteligencia emocional” was used. Findings were filtered to meet inclusion criteria: peer-reviewed, published between 2008-2018, corresponding to a Psychology related subject. Duplicate articles, those that did not contain the term “inteligencia emocional” in the abstract and articles that were not listed under the Psychology category were excluded. Results Data analysis of 19 countries from 2008-2014 revealed the mean number of Emotional Intelligence published articles to be 2.65 (SD = 5.54) articles per country - with a maximum of 22 and a minimum of 0. The percent of articles featuring EI in relation to Total Psychology articles published had a mean of 7% - with Minimum of 0% and Maximum of 60%. Bolivia has the highest percentage of articles on EI (60%), whereas Colombia the highest total number of articles published (n = 41). Population was significantly correlated with Total Articles Published and Total Psychology Articles Published. Conclusions Emotional Intelligence in Latin American countries is not widely investigated. Findings revealed 12 out of 19 Latin American countries had one or more publications related to Emotional Intelligence. While population was shown to be related to the number of articles published in Life Sciences and Psychology, it did not reveal a correlation with the publication of studies regarding EI. Furthermore, education and GDP were not related to the overall publication of articles.


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