scholarly journals Pharmaco-economic features of hospital treatment of acute community-acquired pneumonia in children

2021 ◽  
Vol 25 (3 (99)) ◽  
pp. 77-82
Author(s):  
Y. Nechytailo ◽  
N. Popelyuk ◽  
O. Dolzhenko
Keyword(s):  
Clinical Symptoms ◽  
Community Acquired Pneumonia ◽  
Point Of View ◽  
Fourth Generation ◽  
Hospital Treatment ◽  
Cost Of Treatment ◽  
Economic Point ◽  
Corticosteroid Hormones ◽  
Treatment Measures ◽  
Pathogenetic Therapy

The goal. Тo analyze the features of treatment and medical expenses in children hospitalized for acute community-acquired pneumonia. Materials and methods. The study analyzed medical records and examined 51 children aged 2 to 17 months hospitalized for pneumonia. In patients studied clinical symptoms, severity, structure and duration of basic treatment measures, their cost. Results. The duration of inpatient treatment was 13.3±0.62 days with subsequent outpatient treatment and rehabilitation. Antibiotics, antipyretics, antihistamines, mucolytics and corticosteroid hormones were used in the treatment. The total cost of treatment for one case averaged 2346.9±145.7 hryvnias. The most expensive were the costs of antibiotics, and the cheapest - the antipyretics. Given the community-acquired nature of the process, the initial use of third- and fourth-generation cephalosporins was irrational and significantly increased the cost of treatment. Conclusions. The introduction of a new model of medicine focuses on the optimization of treatment tactics and the rational choice of antibiotics for acute community-acquired pneumonia. In antibacterial therapy is still inadequate, from a clinical and economic point of view, the choice of drugs. In the treatment of this disease, the role of pathogenetic therapy to restore the processes of mucociliary clearance and prevention of dysbiosis on the background of the use of antibiotics has increased.

scholarly journals The effectiveness of moxifloxacin in the treatment of community-acquired pneumonia

2021 ◽  
Vol 4 (2) ◽  
pp. 4-10
Author(s):  
Dmytro Dmytriiev ◽  
Oleksandr Nazarchuk ◽  
Yuliana Babina
Keyword(s):  
Respiratory Tract ◽  
High Efficiency ◽  
Community Acquired Pneumonia ◽  
Fourth Generation ◽  
Infusion Therapy ◽  
International Studies ◽  
Clinical Use ◽  
Cost Of Treatment ◽  
The Cost ◽  
Respiratory Tract Infec

The article presents the results of domestic and international studies of the use of the fourth-generation fluoroquinolone moxifloxacin in the treatment of commu-nity-acquired pneumonia and pneumonia caused by SARS-CoV-2. Analysis of the clinical use of moxifloxacin in the treatment of complications of the respiratory tract infec-tions indicates its high efficiency and bioavailability, a low risk of resistance, which makes it possible to recommend it for widespread use in the work of a practicing doctor. Ge-neric drug Maxicin (Yuria-Pharm), available as a 20 mg/ml concentrate in a 20 ml vial, can significantly reduce the cost of treatment and optimize infusion therapy by choosing both volume and solvent.

scholarly journals Clinical case of pulmonary blastoma in a child as a disguise of community-acquired pneumonia

2021 ◽  
pp. 46-50
Author(s):  
O.V. Dutchuk ◽  
◽  
Z.R. Kocherha ◽  
V.M. Voloshynovych ◽  
Yu.I. Alekseeva ◽  
...  
Keyword(s):  
Clinical Case ◽  
Clinical Laboratory ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Community Acquired Pneumonia ◽  
Pleuropulmonary Blastoma ◽  
Pulmonary Blastoma ◽  
Treatment Measures ◽  
Instrumental Methods ◽  
Methods Of Treatment

Currently, the problem of diagnosing pleuropulmonary blastoma in children remains relevant, because this pathology often runs under the guise of other nosologies, including pneumonia, and is extremely difficult to diagnose. Currently there are no pathognomonic clinical symptoms, specific diagnostic criteria for this disease, almost 60% of patients have nonspecific symptoms. This article presents a rare clinical case of biphasic pulmonary blastoma in a child who was examined and treated at the Ivano-Frankivsk Regional Children's Clinikal Hospital Ivano-Frankivsk Regional Council. The main clinical manifestations, diagnosis and treatment of biphasic blastoma of the lungs in a child based on the observation of a 5-year-old girl who was hospitalized for acute abdominal pain, chest pain and cough. After clinical — laboratory and instrumental methods of examination, right-sided pneumonia and exudative pleurisy were diagnosed. The set of treatment measures did not give the expected positive effect, improving the patient's condition. Additional testing is required for suspected breast cancer. It has been established that the best method for verifying the diagnosis of pulmonary blastoma is multislice computed tomography with intravenous bolus contrast and immunohistochemical examination of the biopsy. The methods of treatment used in this case, including anti-inflammatory and polychemotherapy according to the scheme, the use of radical treatment at the National Cancer Institute in Kyiv — surgery right pneumonectomy with pericardial resection. The child is currently in stable remission for 4.5 years. The described clinical case demonstrates the difficulty of diagnosing lung blastoma in children due to the lack of typical clinical manifestations. The research was carried out in accordance with the principles of the Helsinki declaration. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: children, pneumonia, blastoma, pulmonology, diagnosis, treatment.

scholarly journals THE CLINICAL ECONOMIC ANALYSIS OF SCHEMES OF GRADED ANTI-BACTERIAL THERAPY AS A LEVEL OF AMELIORATION OF QUALITY OF MEDICAL CARE SUPPORT OF PATIENTS WITH UROLOGICAL PATHOLOGY

2019 ◽  
Vol 62 (1) ◽  
pp. 18-23
Author(s):  
Angella A. Dulepova ◽  
O. V. Ruina ◽  
T. V. Pozdeeva ◽  
S. V. Kononova ◽  
D. V. Pisanenko
Keyword(s):  
Efficiency Index ◽  
Application Rate ◽  
Point Of View ◽  
Cost Of Treatment ◽  
Economic Point ◽  
Clinical Efficiency ◽  
Patient Stay ◽  
Quality Of Medical Care ◽  
Care Support

The necessity of implementing clinical economic studies was conditioned by a significant prevalence of infections of urinary tracts, wide variety and high cost of antibacterial pharmaceuticals for their treatment. The sampling included 539 cases of application of step schemes of antibiotics treatment in patients of urological departments in 2014-2015. Overall, six the most prevalent schemes (87.4% of all cases) were picked out. Every scheme was analyzed by application rate, clinical efficiency, treatment cost and average duration of patient stay in hospital. The most clinical efficiency was established for the scheme that included amoxicillin + сlavulanic acid in injection and peroral components without implementing peri-operational antibiotics prevention (97.7%). However, period of hospitalization was in average 2.9 days longer and transition of patient from injection component of therapy to a peroral one occurred 2.3 days later than in case of application of the same pharmaceutical in combination with peri-operational antibiotics prevention (efficiency index 96.0%). It is established that the scheme with amikacin being from economic point of view the most attractive one (cost of treatment is 2.5-6.1 times lower and period of hospitalization the shortest) and differing by high clinical efficiency (95.2%) is applied only in 4.4% of analyzed cases because amikacin has many side effects restricting its application in medical practice. The received information permits physician to rationally prescribe optimal schemes of treatment that decreases costs of therapy, risk of development of complications initiated by antibacterial therapy and also increases quality of life of patient.

Sophie Laws, with Caroline Harper and Rachel Marcus. Research for Development: A Practical Guide. New Delhi: Vistaar Publications. 2003. xiii+475 pages. Paperback. Indian Rupees 450.00.

2003 ◽  
Vol 42 (2) ◽  
pp. 170-172
Author(s):  
Mir Annice Mahmood
Keyword(s):  
Policy Research ◽  
Point Of View ◽  
Basic Question ◽  
New Delhi ◽  
Economic Point ◽  
Scarce Resources ◽  
Is Research ◽  
The Subject ◽  
Development Workers

To implement any successful policy, research about the subject-matter is essential. Lack of knowledge would result in failure and, from an economic point of view, it would lead to a waste of scarce resources. The book under review is essentially a manual which highlights the use of research for development. The book is divided into two parts. Part One informs the reader about concepts and some theory, and Part Two deals with the issue of undertaking research for development. Both parts have 11 chapters each. Chapter 1 asks the basic question: Is research important in development work? The answer is that it is. Research has many dimensions: from the basic asking of questions to the more sophisticated broad-based analysis of policy issues. The chapter, in short, stresses the usefulness of research which development workers ignore at their own peril.

Bleak Weather for Sun-Shine AG: A Case Study of Impairment of Assets

2014 ◽  
Vol 30 (2) ◽  
pp. 113-126 ◽  
Author(s):  
Dominic Detzen ◽  
Tobias Stork genannt Wersborg ◽  
Henning Zülch
Keyword(s):  
Real Life ◽  
Accounting Standards ◽  
Point Of View ◽  
Professional Judgment ◽  
Economic Point ◽  
Instructional Resource

ABSTRACT This case originates from a real-life business situation and illustrates the application of impairment tests in accordance with IFRS and U.S. GAAP. In the first part of the case study, students examine conceptual questions of impairment tests under IFRS and U.S. GAAP with respect to applicable accounting standards, definitions, value concepts, and frequency of application. In addition, the case encourages students to discuss the impairment regime from an economic point of view. The second part of the instructional resource continues to provide instructors with the flexibility of applying U.S. GAAP and/or IFRS when students are asked to test a long-lived asset for impairment and, if necessary, allocate any potential impairment. This latter part demonstrates that impairment tests require professional judgment that students are to exercise in the case.

The Role of Economic Evaluation in Dissemination and Implementation Research

2017 ◽  
Author(s):  
Ramesh Raghavan
Keyword(s):  
Service Providers ◽  
Implementation Strategies ◽  
Cost Effective ◽  
Point Of View ◽  
Dissemination And Implementation ◽  
Economic Point ◽  
Open Questions ◽  
Public Health Organizations ◽  
Quality Health ◽  
Dissemination And Implementation Research

This chapter presents an overview of how D&I research can be evaluated from an economic point of view. Dissemination and implementation imposes costs upon knowledge purveyors, provider organizations, public health organizations, and payers (including governments). However, whether these added costs will result in improved service delivery and, perhaps more importantly, client outcomes and improvements in population health remain as open questions. If emerging studies reveal that defined implementation strategies are more cost effective than “usual” implementation, then policymakers and service providers will need to resource these added costs of implementation in order to assure the success and sustainability of high-quality health services over the long term.

scholarly journals The “Zero Miles Product” Concept Applied to Biofuel Production: A Case Study

Energies ◽  
2021 ◽  
Vol 14 (3) ◽  
pp. 565
Author(s):  
Nikolaj Kaae Kirk ◽  
Clara Navarrete ◽  
Jakob Ellegaard Juhl ◽  
José Luis Martínez ◽  
Alessandra Procentese
Keyword(s):  
Sugar Content ◽  
Point Of View ◽  
Biofuel Production ◽  
Transport Costs ◽  
Economic Point ◽  
Product Concept ◽  
Energy Demands ◽  
Production Platform ◽  
High Sugar Content

To make biofuel production feasible from an economic point of view, several studies have investigated the main associated bottlenecks of the whole production process through approaches such as the “cradle to grave” approach or the Life Cycle Assessment (LCA) analysis, being the main constrains the feedstock collection and transport. Whilst several feedstocks are interesting because of their high sugar content, very few of them are available all year around and moreover do not require high transportation’ costs. This work aims to investigate if the “zero miles” concept could bring advantages to biofuel production by decreasing all the associated transport costs on a locally established production platform. In particular, a specific case study applied to the Technical University of Denmark (DTU) campus is used as example to investigate the advantages and feasibility of using the spent coffee grounds generated at the main cafeteria for the production of bioethanol on site, which can be subsequently used to (partially) cover the campus’ energy demands.

scholarly journals Comparison between Concentrated Solar Power and Gas-Based Generation in Terms of Economic and Flexibility-Related Aspects in Chile

Energies ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 1063
Author(s):  
Catalina Hernández Moris ◽  
Maria Teresa Cerda Guevara ◽  
Alois Salmon ◽  
Alvaro Lorca
Keyword(s):  
Natural Gas ◽  
Solar Power ◽  
Renewable Energy Sources ◽  
Cost Effective ◽  
Hybrid Plant ◽  
Point Of View ◽  
Concentrated Solar Power ◽  
Economic Point ◽  
Hybrid Plants ◽  
Cost Of Energy

The energy sector in Chile demands a significant increase in renewable energy sources in the near future, and concentrated solar power (CSP) technologies are becoming increasingly competitive as compared to natural gas plants. Motivated by this, this paper presents a comparison between solar technologies such as hybrid plants and natural gas-based thermal technologies, as both technologies share several characteristics that are comparable and beneficial for the power grid. This comparison is made from an economic point of view using the Levelized Cost of Energy (LCOE) metric and in terms of the systemic benefits related to flexibility, which is very much required due to the current decarbonization scenario of Chile’s energy matrix. The results show that the LCOE of the four hybrid plant models studied is lower than the LCOE of the gas plant. A solar hybrid plant configuration composed of a photovoltaic and solar tower plant (STP) with 13 h of storage and without generation restrictions has an LCOE 53 USD/MWh, while the natural gas technology evaluated with an 85% plant factor and a variable fuel cost of 2.0 USD/MMBtu has an LCOE of 86 USD/MWh. Thus, solar hybrid plants under a particular set of conditions are shown to be more cost-effective than their closest competitor for the Chilean grid while still providing significant dispatchability and flexibility.

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