scholarly journals Effects of High-intensity Exercise and Fish Oil-induced Oxidative Stress

2003 ◽  
Vol 9 (2) ◽  
pp. 89-96
Author(s):  
Chen Yi YAU ◽  
Shu Chen SHEN ◽  
Sandy HSIEH

LANGUAGE NOTE | Document text in Chinese; abstract also in English.High-intensity exercise may induce active oxygen free radicals higher. Fish oil, which is one of the CO-3 PUFA series that can decrease TG and influence plasma lipids, appears to prevent arteriosclerosis and CHD, but some evidence describe it increases the lipid peroxidation in the cell. Fish oil would then seem to influence the antioxidant defense system that causes damage or disease. This study investigates the effects on the antioxidant defence system of combining high-intensity exercise with fish oil supplementation. Methods: Thirty-three healthy males were randomly assigned into four groups (20.3±1.4 yrs; 64.3±7.9 kg), which were given set combinations of dietary fish oil (9 g per day), exercise (intensity 85-90 % HRmax reserve), and placebos. The experiment lasted 4 weeks in total. Venous samples were obtained prior to exercise and within 5 min after. 4 venous samples were also taken from fish oil groups during the four-week period. Blood from all groups was analyzed for sesuperoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total glutathione (T-GSH), total antioxidant ability (TAA), malodialdehyde (MDA). A Generalized Estimating Equations (G.E.E.) method was used for data analysis. Results: In the fish oil groups SOD activity significantly increased 11.27 kU/g-HB(P

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Francisco J. Pellegrino ◽  
Analía Risso ◽  
Yanina Corrada ◽  
Rocío C. Gambaro ◽  
Analía I. Seoane

2018 ◽  
Vol 53 (4) ◽  
pp. 293-298
Author(s):  
S. Salehi ◽  
MR. Bayatiani ◽  
P. Yaghmaei ◽  
S. Rajabi ◽  
MT. Goodarzi ◽  
...  

Ionizing radiation interacts with biomolecules to produce free radicals, which can damage all components of the cell. The aim of this study was to evaluate the protective effects of different doses of resveratrol against X-ray-induced damage in male rat. The animals were divided into five groups, each composed of six rats: two groups as control groups received saline or ethanol (ethanol in saline, 25%, V/V as a vehicle). Two groups received resveratrol (5 and 10 mg/kg.bwt) for 30 days before X-ray exposure. One group received X-ray. The rats were sacrificed 24 h after the last exposure, blood samples were collected and serum level of malondialdehyde (MDA), total antioxidant capacity (TAC), and the activities of superoxide dismutase (SOD) and catalase (CAT) were measured by spectrophotometric method. X-ray irradiation significantly increased the levels of MDA and decreased TAC as well as SOD activity as compared with control groups. Furthermore, resveratrol pretreatment led to remarkable decrease in MDA concentration and increase in the activities of SOD and CAT as well as TAC compared to those of controls. Our results revealed antioxidant properties of resveratrol and suggest it as a potent radioprotector to ameliorate X-irradiation induced damage in the body.


2013 ◽  
Vol 99 (2) ◽  
pp. 543-550.e1 ◽  
Author(s):  
Jennifer L. Herington ◽  
Dana R. Glore ◽  
John A. Lucas ◽  
Kevin G. Osteen ◽  
Kaylon L. Bruner-Tran

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Jie Luo ◽  
Feiruo Huang ◽  
Chenglin Xiao ◽  
Zhengfeng Fang ◽  
Jian Peng ◽  
...  

The study was conducted to investigate whether dietary fish oil could influence growth of piglets via regulating the expression of proinflammatory cytokines. A split-plot experimental design was used with sow diet effect in the main plots and differing piglet diet effect in the subplot. The results showed that suckling piglets from fish oil fed dams grew rapidly (P<0.05) than control. It was also observed that these piglets had higher ADG, feed intake, and final body weight (P<0.05) during postweaning than those piglets from lard fed dams. Furthermore, there was a significant decrease (P<0.01) in the expression of interleukin 6 and tumor necrosis factor-αinlongissimus dorsimuscle. In contrast, there was a tendency (P<0.10) towards lower ADG and higher feed : gain in weaned piglets receiving fish oil compared with those receiving lard. Meanwhile, splenic proinflammatory cytokines expression was increased (P<0.01) in piglets receiving fish oil during postweaning period. The results suggested that 7% fish oil addition to sows' diets alleviated inflammatory response via decreasing the proinflammatory cytokines expression in skeletal muscle and accelerated piglet growth. However, 7% fish oil addition to weaned piglets' diets might decrease piglet growth via increasing splenic proinflammatory cytokines expression.


Cytokine ◽  
2002 ◽  
Vol 19 (5) ◽  
pp. 213-217 ◽  
Author(s):  
W BLOK ◽  
M RABINOVITCH ◽  
V ZILBERFARB ◽  
M NETEA ◽  
W BUURMAN ◽  
...  

1988 ◽  
Vol 18 (6) ◽  
pp. 1267-1273 ◽  
Author(s):  
Anne H. Kettler ◽  
Robert E. Baughn ◽  
Ida F. Orengo ◽  
Homer Black ◽  
John E. Wolf

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