Effects of High-intensity Exercise and Fish Oil-induced Oxidative Stress
LANGUAGE NOTE | Document text in Chinese; abstract also in English.High-intensity exercise may induce active oxygen free radicals higher. Fish oil, which is one of the CO-3 PUFA series that can decrease TG and influence plasma lipids, appears to prevent arteriosclerosis and CHD, but some evidence describe it increases the lipid peroxidation in the cell. Fish oil would then seem to influence the antioxidant defense system that causes damage or disease. This study investigates the effects on the antioxidant defence system of combining high-intensity exercise with fish oil supplementation. Methods: Thirty-three healthy males were randomly assigned into four groups (20.3±1.4 yrs; 64.3±7.9 kg), which were given set combinations of dietary fish oil (9 g per day), exercise (intensity 85-90 % HRmax reserve), and placebos. The experiment lasted 4 weeks in total. Venous samples were obtained prior to exercise and within 5 min after. 4 venous samples were also taken from fish oil groups during the four-week period. Blood from all groups was analyzed for sesuperoxide dismutase (SOD), glutathione peroxidase (GSH-Px), total glutathione (T-GSH), total antioxidant ability (TAA), malodialdehyde (MDA). A Generalized Estimating Equations (G.E.E.) method was used for data analysis. Results: In the fish oil groups SOD activity significantly increased 11.27 kU/g-HB(P