scholarly journals Secondary diseases of infectious and non-infectious origin in patients diagnosed with COVID-19

2021 ◽  
Vol 7 (Extra-A) ◽  
pp. 76-85
Author(s):  
Vitaly Viktorovich Goncharov ◽  
Mikhail Andreevich Ugrovatov ◽  
Harun Achmad ◽  
Nelly Al Audah ◽  
Mariya Andreevna Kishkina
Keyword(s):  
Respiratory Diseases ◽  
Healthcare Professionals ◽  
Evidence Based ◽  
Front Line ◽  
Negative Effects ◽  
Obstructive Pulmonary Disease ◽  
Policy Makers ◽  
Mortality And Morbidity ◽  
Infectious Origin ◽  
Secondary Diseases

  The article considers the features of the occurrence and course of secondary diseases of infectious and non-infectious genesis in patients with a diagnosis of COVID-19, and also examines individual clinical cases described in the literature. The author concludes that the results showed that major respiratory diseases, in particular COPD (chronical obstructive pulmonary disease) and smoking, are associated with severe COVID-19 outcomes. The results of this study can help policy makers, doctors and healthcare professionals in the front line to make evidence-based decisions and reduce the mortality and morbidity of this 21st century pandemic. Understanding the proportion of COVID-19 patients with acute respiratory bacterial co-infection and pathogens is critical for the treatment of COVID-19 patients and helps ensure responsible use of antibiotics and minimize the negative effects of overuse. In addition, this knowledge may have a significant impact on clarifying recommendations for empirical antibiotic therapy for patients with COVID-19.      

scholarly journals Development of a Consumer Engagement Framework

2016 ◽  
Vol 11 (1) ◽  
pp. 46-49
Author(s):  
Lucylynn Lizarondo ◽  
Kate Kennedy ◽  
Debra Kay
Keyword(s):  
Healthcare Professionals ◽  
Evidence Based Practice ◽  
International Association ◽  
Model Development ◽  
Evidence Based ◽  
Strategic Partnerships ◽  
Consumer Engagement ◽  
Policy Makers ◽  
Australian Health ◽  
Group Experience

Objective: The purpose of this project was to develop a Consumer Engagement Model to plan for effective baby boomer engagement to inform policy makers in the healthcare system. This is the first stage of that process. Design: Initial model development for healthcare systems based on literature review and author group experience in evidence-based practice and research, and consumer advocacy and engagement. Setting and population: South Australian health and community service systems, and healthcare professionals that work with baby boomers. Findings: To develop an evidence-based Consumer Engagement Plan, it is recommended that policy makers undertake the four steps outlined in this document to design a question, determine consumer and community segments and scope of engagement, determine the breadth and depth of engagement and address the implications, assess risk and develop strategic partnerships to ensure the Plan is evidencebased,reasonable and achievable. Conclusions: We believe this process provides a framework for planning consumer engagement and for implementation, monitoring, evaluation and review of consumer engagement for policy excellence. We propose to undertake a validation of the model thus populating the model with examples of practice-based strategies and revising the model accordingly. Abbreviations: EBP – Evidence-Based Practice; IAP2 – International Association of Public Participation; PIO – Patient Intervention and Outcome.

Oxford Handbook of Clinical Pharmacy

2017 ◽  
Keyword(s):  
Clinical Pharmacy ◽  
Neurological Disorders ◽  
Respiratory Diseases ◽  
Clinical Skills ◽  
Chronic Obstructive ◽  
Evidence Based ◽  
Drug Management ◽  
Obstructive Pulmonary Disease ◽  
Controlled Drugs ◽  
User Friendly

Fully updated and revised, the third edition of the Oxford Handbook of Clinical Pharmacy presents practical guidance in a user-friendly format. Supported by prescribing points and linked relevant concepts, it will give you the support and knowledge to practise with confidence. Including key information on controlled drugs, adverse drug reactions and interactions, clinical skills, patient and drug management, as well as therapy-specific issues, this handbook now includes brand new topics covering chronic obstructive pulmonary disease and other respiratory diseases, HIV, tuberculosis, mental health and neurological disorders, health coaching, and applications to formulary committees. With an increased focus on supporting the community pharmacist and designed to complement the British National Formulary guidelines, this handbook is packed with evidence-based advice.

scholarly journals The accuracy of the heat index to explain the excess of mortality and morbidity during heat waves – a case study in a mediterranean climate

2013 ◽  
Vol 20 (20) ◽  
pp. 71-84 ◽  
Author(s):  
Ana Monteiro ◽  
Vânia Carvalho ◽  
Sara Velho ◽  
Carlos Sousa
Keyword(s):  
Heat Wave ◽  
Respiratory Diseases ◽  
Heat Waves ◽  
Heat Index ◽  
Respiratory Morbidity ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Mortality And Morbidity ◽  
Comfort Index ◽  
T Distribution

Abstract The aim of this contribution was to evaluate the accuracy of a well known human comfort index, the heat index, to anticipate the effects of the July 2006 heat wave in mortality (all causes) and morbidity (all causes, respiratory and circulatory disease). Our assessment was done to all citizens, to people of the 75+ cohort and to each gender, in Porto. For further statistical analysis, we calculated an expected number of admissions by averaging the admissions recorded during the comparison period. The 95% confidence interval was calculated, using a standard method based on the t-distribution, for differences between independent means with different population variances, using the Leveane test to evaluate the variance’s homogeneity. During the 2006 heat wave, a 52% mortality excess was registered relatively to the expected mortality (p < 0.001), for all cohorts of the population. The admissions excess for all ages included the admissions due to respiratory diseases (p < 0.029), pneumonia (p < 0.001) and chronic obstructive pulmonary disease (p < 0.001). For the 75+ cohort, the admissions due to respiratory diseases (p < 0.017), pneumonia (p < 0.001) and heart failure (p < 0.610) were also statistically high. The obtained results confirm that the heat index is a truthful method to anticipate the negative impacts of heat waves in human health even in climate contexts adapted to hot summers like at Porto - a Mediterranean tempered climate. The impacts of July 2006’s heat wave in the increase of mortality (all causes) and in respiratory morbidity (all population and 75+cohort) was evident.

Evidence-Based Smoking Cessation Interventions for Patients With Acute Respiratory Disorders

2009 ◽  
Vol 27 (1) ◽  
pp. 273-296 ◽  
Author(s):  
Janie Heath ◽  
Sara Young ◽  
Sharon Bennett ◽  
Mary Beth Ginn ◽  
Geoffrey Cox
Keyword(s):  
Respiratory Diseases ◽  
Tobacco Cessation ◽  
Hospital Admissions ◽  
Models Of Care ◽  
Community Acquired Pneumonia ◽  
Chronic Obstructive ◽  
Evidence Based ◽  
Obstructive Pulmonary Disease ◽  
Respiratory Illnesses ◽  
The One

Worldwide, tobacco use continues to be the most significant preventable cause of death and hospital admissions, particularly related to respiratory diseases. Acute respiratory illnesses requiring hospitalization provide an opportunity for nurses to intervene and help smokers quit. Of the three top hospital admissions related to respiratory diseases, chronic obstructive pulmonary disease (COPD) is the one that continues to have increased mortality whereas community acquired pneumonia and asthma have decreased over the past 5 years. The course of all three can be caused or exacerbated by continued smoking. This review describes the state of the science of nursing research focused on tobacco cessation interventions for hospitalized patients with COPD, asthma, or community acquired pneumonia. Additionally, we describe two evidence-based, nurse-driven, hospital protocols to treat tobacco dependence that can serve as models of care. Recommendations are made as to how to effectively promote nursing interventions for tobacco cessation in the acute care setting.

scholarly journals Comparison of SpO2 and heart rate values on Apple Watch and conventional commercial oximeters devices in patients with lung disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Leonardo Zumerkorn Pipek ◽  
Rafaela Farias Vidigal Nascimento ◽  
Milena Marques Pagliarelli Acencio ◽  
Lisete Ribeiro Teixeira
Keyword(s):  
Heart Rate ◽  
Lung Disease ◽  
Skin Color ◽  
Lung Diseases ◽  
Chronic Obstructive ◽  
Negative Effects ◽  
Obstructive Pulmonary Disease ◽  
Mortality And Morbidity ◽  
Positive Correlations ◽  
Pulse Oximeters

AbstractLung diseases have high mortality and morbidity, with an important impact on quality of life. Hypoxemic patients are advised to use oxygen therapy to prolong their survival, but high oxygen saturation (SpO2) levels can also have negative effects. Pulse oximeters are the most common way to assess oxygen levels and guide medical treatment. This study aims to assess whether wearable devices can provide precise SpO2 measurements when compared to commercial pulse oximeters. This is a cross-section study with 100 patients with chronic obstructive pulmonary disease and interstitial lung disease from an outpatient pneumology clinic. SpO2 and heart rate data were collected with an Apple Watch Series 6 (Apple) and compared to two commercial pulse oximeters. The Bland–Altman method and interclass correlation coefficient were used to compare their values. We observed strong positive correlations between the Apple Watch device and commercial oximeters when evaluating heart rate measurements (r = 0.995, p < 0.001) and oximetry measurements (r = 0.81, p < 0.001). There was no statistical difference in the evaluation of skin color, wrist circumference, presence of wrist hair, and enamel nail for SpO2 and heart rate measurements in Apple Watch or commercial oximeter devices (p > 0.05). Apple Watch 6 is a reliable way to obtain heart rate and SpO2 in patients with lung diseases in a controlled environment.

The Preschool Stuttering Screen for Health Care Professionals

2011 ◽  
Vol 21 (2) ◽  
pp. 59-62
Author(s):  
Joseph Donaher ◽  
Christina Deery ◽  
Sarah Vogel
Keyword(s):  
Risk Factors ◽  
Health Care ◽  
Differential Diagnosis ◽  
Preschool Children ◽  
Health Care Professionals ◽  
Healthcare Professionals ◽  
Evidence Based ◽  
Developmental Profile

Healthcare professionals require a thorough understanding of stuttering since they frequently play an important role in the identification and differential diagnosis of stuttering for preschool children. This paper introduces The Preschool Stuttering Screen for Healthcare Professionals (PSSHP) which highlights risk factors identified in the literature as being associated with persistent stuttering. By integrating the results of the checklist with a child’s developmental profile, healthcare professionals can make better-informed, evidence-based decisions for their patients.

A LOOK INTO THE HISTORY OF THE PREPARATION OF LOCAL PROFESSIONALS IN THE INDUSTRY

2019 ◽  
Vol 26 (2) ◽  
pp. 4-8
Author(s):  
Toshkentboy Pardaev ◽  
◽  
Zhavli Tursunov
Keyword(s):  
Evidence Based ◽  
Local Policy ◽  
Soviet Government ◽  
Policy Makers ◽  
History Of

In the article : In the second half of the 20 century the process of preparation of local experts in South Uzbekistan industry changes in this field a clear evidence-based analysis of the problematic processes that resulted from the discriminatory policy toward the Soviet government-dominated local policy makers

OCCURRENCE OF THE RISKS FOR DEVELOPMENT OF RESPIRATORY DISEASES IN CHILDREN EXPOSED TO THE CHEMICAL FACTORS OF THE EXPOSURE OF ALUMINA REFINERY- ASSOCIATED BUSINESS ACTIVITY

2019 ◽  
pp. 42-47 ◽  
Author(s):  
M.A. Zemlianova ◽  
I.V. Tikhonova
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Allergic Inflammation ◽  
Respiratory Morbidity ◽  
Upper Respiratory Tract ◽  
Negative Effects ◽  
Wide Range ◽  
Chemical Factors ◽  
Chronic Lymphoproliferative Diseases

Alumina refineries are among the leading sources of atmospheric air pollution with a wide range of pollutants hazardous to human respiratory organs. It is relevant to study and evaluate the occurrence of the risks for development of respiratory diseases in children living in the area affected by the emission components of an alumina refinery. We assessed air quality of the area under observation and comparison according to monitoring observations, risk of non-carcinogenic effects from the respiratory organs. The content of chemicals in the blood and urine adequate to risk factors was quantified. The structure of individual groups of respiratory diseases was analyzed. The causal relationships of violations of laboratory parameters with an increased content of chemicals in biological media were evaluated. It was found that an aerogenic exposure of chemical pollutants is formed on the territory with the production of metallurgical alumina. It determines the risk for development of respiratory diseases, exceeding an acceptable level up to 49.9 times. In the exposed children, the content of manganese, chromium, nickel, copper, xylenes, formaldehyde and aluminum, fluoride ion in the urine was increased to 4.2 times in relation to the indices in the comparison group. A high level of additional respiratory morbidity(1.8 times) was revealed. Chronic lymphoproliferative diseases of the nasopharynx and inflammatory diseases of the upper respiratory tract (up to 6.6 times more often), inflammatory diseases with a predominance of the mechanism of allergic inflammation ( up to 2.1 times more often)are more often detected in the framework of the respiratory diseases. Negative effects on the part of the respiratory system in the form of activation of antioxidant processes, the development of an inflammatory reaction, local, general and specific sensitization of the respiratory tract were established. It confirms the occurrence of the risks for the development of respiratory diseases in children in the exposure area of the chemical factors of alumina refinery-associated economic activity.

CRISPR/Cas9 Genome Editing Tool: A Promising Tool for Therapeutic Applications on Respiratory Diseases

2020 ◽  
Vol 20 (5) ◽  
pp. 333-346
Author(s):  
Sadiya Bi Shaikh ◽  
Yashodhar Prabhakar Bhandary
Keyword(s):  
Respiratory Diseases ◽  
Gene Editing ◽  
Epithelial Mesenchymal Transition ◽  
Respiratory Health ◽  
Chronic Obstructive ◽  
Therapeutic Tool ◽  
Obstructive Pulmonary Disease ◽  
Mesenchymal Transition ◽  
Chronic Respiratory Diseases ◽  
Promising Tool

Respiratory diseases are one of the prime topics of concern in the current era due to improper diagnostics tools. Gene-editing therapy, like Clustered regularly interspaced palindromic repeats- associated nuclease 9 (CRISPR/Cas9), is gaining popularity in pulmonary research, opening up doors to invaluable insights on underlying mechanisms. CRISPR/Cas9 can be considered as a potential gene-editing tool with a scientific community that is helping in the advancement of knowledge in respiratory health and therapy. As an appealing therapeutic tool, we hereby explore the advanced research on the application of CRISPR/Cas9 tools in chronic respiratory diseases such as lung cancer, Acute respiratory distress syndrome (ARDS) and cystic fibrosis (CF). We also address the urgent need to establish this gene-editing tool in various other lung diseases such as asthma, Chronic obstructive pulmonary disease (COPD) and Idiopathic pulmonary fibrosis (IPF). The present review introduces CRISPR/Cas9 as a worthy application in targeting epithelial-mesenchymal transition and fibrinolytic system via editing specific genes. Thereby, based on the efficiency of CRISPR/Cas9, it can be considered as a promising therapeutic tool in respiratory health research.

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