scholarly journals Antibacterial Activity of Amine-Functionalized Silver-Loaded Natural Zeolite Clinoptilolite

2021 ◽  
Vol 15 (1) ◽  
pp. 13
Author(s):  
Nik Ahmad Nizam Nik Malek ◽  
Siti Aishah Mohd Hanim
Keyword(s):  
Antibacterial Activity ◽  
Natural Zeolite ◽  
Metal Ion ◽  
Silver Ions ◽  
Exchange Capacity ◽  
Carrier System ◽  
Amine Functionalized ◽  
Inhibition Concentration ◽  
Diffusion Technique

The antibacterial activity of amine-functionalized silver-loaded natural zeolite clinoptilolite was analysed against Gram-negative Escherichia coli ATCC 11229 and a comparison was made with raw clinoptilolite, silver-loaded clinoptilolite, and amine-functionalized clinoptilolite with APTES (3-Aminopropyl) triethoxysilane. Results from the characterization of the samples using Fourier transform infrared (FTIR) spectroscopy showed that the silver-loaded clinoptilolite was functionalized with APTES without affecting the original framework structure of the clinoptilolite. The antibacterial activity of the analysed samples based on disc diffusion technique (DDT) and minimum inhibition concentration (MIC) showed that the silver-loaded clinoptilolite (150 % of cation exchange capacity of clinoptilolite) had the highest antibacterial activity, as compared to amine-functionalized silver-loaded zeolite. This study showed that the functionalization of silver-loaded clinoptilolite could affect the release and action of silver ions to kill or inhibit bacterial growth. However, it showed that the natural zeolite clinoptilolite could become a good carrier system for the antibacterial metal ion, especially silver ions.   Keywords: Zeolite, clinoptilolite, antibacterial agent, silver, amine-functionalization    

Antibacterial Activity of Amine-Functionalized Zeolite NaY against Staphylococcus aureus ATCC6538 and Escherichia coli ATCC11229

2015 ◽  
Vol 761 ◽  
pp. 402-406 ◽  
Author(s):  
Siti Aishah Mohd Hanim ◽  
Nik Ahmad Nizam Nik Malek ◽  
Zaharah Ibrahim ◽  
Mashitah Mad Salim ◽  
Nur Isti'anah Ramli ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Inhibition Zone ◽  
Antibacterial Activities ◽  
Gram Positive ◽  
Gram Negative ◽  
Zeolite Nay ◽  
Amine Functionalized ◽  
Diffusion Technique

The antibacterial activity of functionalized zeolite NaY (CBV100) with different concentrations of 3-aminopropyltriethoxysilane (APTES) (0.01, 0.05, 0.20 and 0.40 M) was studied against Staphylococcus aureus ATCC 6538 (Gram positive) and Escherichia coli ATCC 11229 (Gram negative) through disc diffusion technique (DDT). The characterization of functionalized zeolite NaY with fourier transform infrared (FTIR) spectroscopy indicated the attachment of APTES on zeolite NaY. Through DDT, the inhibition zone of functionalized zeolite NaY increased proportionally to the amount of the amine-functional group attached onto zeolite NaY. Functionalized zeolite NaY showed higher antibacterial activity against Gram-positive compared to Gram-negative bacteria. It can be concluded from this study that amine-functionalized zeolite NaY shows evidence of antibacterial activities.

scholarly journals Structural Characterization and Antibacterial Activity of Antibiotic Streptomycin Immobilized on Zeolite Synthesized from Natural Kaolinite

2021 ◽  
Vol 11 (5) ◽  
pp. 13573-13586
Keyword(s):  
Electron Microscopy ◽  
Antibacterial Activity ◽  
Hydrothermal Process ◽  
Antibacterial Activities ◽  
Good Prospect ◽  
X Ray ◽  
Gram Positive Bacteria ◽  
Transmission Electron ◽  
Inhibition Concentration ◽  
Diffusion Technique

This study evaluated the efficacy of antibacterial activities for a zeolite A (ZEO) sample loaded with streptomycin (STR). The ZEO was synthesized from kaolinite (KAO) via the alkaline hydrothermal process and verified with various techniques, such as X-ray Diffraction, Fourier-Transform Infrared spectroscopy, Field Emission Scanning Electron Microscopy with Energy Dispersive X-ray, Transmission Electron Microscopy, and dispersion behavior to confirm the production of ZEO with high purity and reproducibility. The cubic framework of ZEO was maintained after the immobilization of STR, indicating STR molecules' adsorption on the ZEO surface. The STR-loaded ZEO (ZS) samples were prepared in three STR concentrations (50, 100, and 200 mg/L). The samples' antibacterial activity was determined using the disc diffusion technique and minimum inhibition concentration against Gram-negative bacteria (Escherichia coli ATCC 11229) and Gram-positive bacteria (Staphylococcus aureus ATCC 6538). Both bacteria were susceptible to ZS, which showed an antibacterial effect directly proportional to the STR concentration. Thus, the synthesized ZEO synthesized from natural KAO had a good prospect as a carrier system for STR for generating a broad spectrum of antibacterial activity.

Antibacterial Activity of Copper and CTAB Modified Clays against Pseudomonas aeruginosa

2012 ◽  
Vol 626 ◽  
pp. 178-182 ◽  
Author(s):  
Nik Ahmad Nizam Nik Malek ◽  
Siti Amirah Ishak ◽  
Mohammed Rafiq Abdul Kadir
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Antibacterial Agents ◽  
Ammonium Bromide ◽  
X Ray Diffraction ◽  
X Ray ◽  
Inhibition Concentration ◽  
Antibacterial Assay ◽  
Cetyltrimethyl Ammonium

Antibacterial activity of modified kaolinite and bentonite with antibacterial agents againstPseudomonas aeruginosawas studied. These clays have been modified with only cetyltrimethyl ammonium bromide (CTAB) and copper (Cu) and the combination of both. Characterization of the studied materials with X-Ray Diffraction (XRD), Fourier Transform-Infrared (FTIR) spectroscopy, Energy Dispersive X-ray (EDX) analyzer and Field Emission-Scanning Electron Microscopy (FESEM) revealed the successful preparation of CTAB-clays, Cu-clays and CTAB-Cu-clays without distorting the structure of these clays. From the antibacterial assay of the studied materials by Inhibition Growth Study and Minimum Inhibition Concentration (MIC) technique, CTAB-Cu-clays have been proven to have the highest antibacterial activity due to the synergistic effect of CTAB and Cu as antibacterial agents. It can be concluded that modification of clays with CTAB and Cu can become new alternative powerful antibacterial agent.

scholarly journals Synthesis and Characterization of Nanomaterial Based on Halloysite and Hectorite Clay Minerals Covalently Bridged

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 506
Author(s):  
Marina Massaro ◽  
Cesar Viseras Iborra ◽  
Giuseppe Cavallaro ◽  
Carmelo Giuseppe Colletti ◽  
Fátima García-Villén ◽  
...  
Keyword(s):  
External Surface ◽  
Silver Ions ◽  
Halloysite Nanotubes ◽  
Exchange Capacity ◽  
Covalent Modification ◽  
Proof Of Concept ◽  
Adsorption Ability ◽  
Cp Mas Nmr ◽  
Straightforward Approach

Halloysite is an aluminosilicate clay with a predominantly hollow tubular structure (HNTs) able to act as a nanocontainer for the encapsulation of several chemicals. However, HNTs possess low affinity for metal ions in their pristine form and they need to be modified for improving their adsorption capabilities. Therefore, to overcome this issue herein we report a straightforward approach for the covalent modification of the external surface of halloysite nanotubes with hectorite clay. Compared to halloysite, hectorite possesses a lamellar structure with higher cation exchange capacity. The covalent linkage between the two clays was verified by several techniques (FTIR spectroscopy, 13C CP-MAS NMR, TGA, ζ−potential, DLS, and XRD measurements) and the morphology was imaged by TEM investigations. As proof of concept the adsorption ability of the obtained nanomaterial in comparison to pristine clays was proved using ciprofloxacin and silver ions chosen as models for their different chemical characteristics.

scholarly journals Silver(I)-complexes with an itaconic acid-based hydrogel

2009 ◽  
Vol 63 (3) ◽  
pp. 137-142 ◽  
Author(s):  
Maja Micic ◽  
Simonida Tomic ◽  
Jovanka Filipovic ◽  
Edin Suljovrujic
Keyword(s):  
Antibacterial Activity ◽  
Itaconic Acid ◽  
Smart Materials ◽  
Inductively Coupled Plasma ◽  
Metal Ion ◽  
Aqueous Media ◽  
Silver Ions ◽  
Metal Ion Binding ◽  
Fluid Uptake

Silver(I) itaconic acid-based hydrogel complexes were synthesized and characterized in order to examine the potential use of these systems; FTIR, AFM, in vitro fluid-uptake, metal sorption and antibacterial activity assay measurements were used for the characterization. Metal (silver(I)) ion uptaken by IA-based hydrogels was determined by inductively coupled plasma mass spectrometry. The coordination sites for metal ions were identified and the stability in in vitro condition was determined. Incorporation of silver(I) ions into hydrogels and the influence of these ions on the diffusion properties of hydrogels were analyzed and discussed, too; it was found that the itaconic acid moiety in hydrogels is the determining factor which influences metal ion binding and therefore fluid uptake inside the polymeric network. Furthermore, silver(I) itaconic acid-based hydrogel showed a satisfactory antibacterial activity. The most advanced feature of these materials is that the silver ions embedded throughout the networks leaches out via controlled manner with time in aqueous media. Therefore, the ions escape from the swollen networks with time and interact with the bacteria. Because of a good dispersion of silver ions in Ag(I)-P(HEMA/2IA) hydrogel complex, we have evaluated the antibacterial activity for this sample. As expected, the number of colonies grown surrounding the Ag(I)- -P(HEMA/2IA) hydrogel complex was found to be almost nil, whereas the pure P(HEMA/2IA) hydrogel did not show any effect on Escherichia coli. Therefore, we conclude that the Ag(I)-P(HEMA/IA) hydrogel complexes are excellent antibacterial materials. Due to these facts, the silver ion IA- -based hydrogel complexes reported here might be used as smart materials in the range of biomedical applications, including drug-delivery devices, biosensors, wound healing dressings, tissue reconstruction and organ repair.

Extraction and characterization of sea anemones compound and its Anti bacterial and hemolytic studies

2020 ◽  
Vol 10 (4) ◽  
pp. 93-97
Author(s):  
Anil Kumar A ◽  
Raja Sheker K ◽  
Naveen B ◽  
Abhilash G ◽  
Akila CR
Keyword(s):  
Antibacterial Activity ◽  
Focal Point ◽  
Haemolytic Activity ◽  
Klebsiella Pneumonia ◽  
Bacterial Strains ◽  
Sea Anemones ◽  
Marine Plants ◽  
Heteractis Magnifica ◽  
Trididemnum Solidum

Seas assets that give us a variety of characteristic items to control bacterial, contagious and viral ailment and mostly utilized for malignancy chemotherapy practically from spineless creatures, for example, bryozoans, wipes, delicate corals, coelenterates, ocean fans, ocean bunnies, molluscs and echinoderms. In the previous 30 - 40 years, marine plants and creatures have been the focal point of overall endeavours to characterize the regular results of the marine condition. Numerous marine characteristic items have been effectively exceptional to the last phases of clinical preliminaries, including dolastatin-10, a group of peptides disengaged from Indian ocean rabbit, Dollabella auricularia. Ecteinascidin-743 from mangrove tunicate Ecteinascidia turbinata, Didemnins was isolated from Caribbean tunicate Trididemnum solidum and Conopeptides from cone snails (Conus sp.), and a developing number of up-and-comers have been chosen as promising leads for expanded pre-clinical appraisals. Sea anemones possess numerous tentacles containing stinging cells or cnidocytes. The stinging cells are equipped with small organelles known as nematocysts. The two species of sea anemones namely, Heteractis magnificaandStichodactyla haddoni, were collected from Mandapam coastal waters of Ramanathapuram district, Tamilnadu, India. The Nematocyst was collected and centrifuged, and the supernatant was lyophilized and stored for further analysis. The amount of protein from Heteractis Magnifica and Stichodactyla haddoni was estimated. The crude extract has shown haemolytic activity on chicken blood and goat blood. In the antibacterial activity of the sea anemone against six bacterial strains Staphylococcus aureus, Salmonella typhii, Salmonella paratyphii, Klebsiella pneumonia, Vibrio cholerae, Pseudomonas aeruginosa. Antibacterial activity of H. Magnifica and S.haddoni was measured as the radius of the zone of inhibition.

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