scholarly journals Aspecte juridice privind sănătatea publică în contextul istoric al marilor epidemii

2021 ◽  
Vol 65 (4) ◽  
pp. 286-306
Author(s):  
Marius Floare ◽  
Keyword(s):  
Public Health ◽  
North America ◽  
Infectious Diseases ◽  
Public Order ◽  
Medical Interventions ◽  
Historical Method ◽  
Contagious Diseases ◽  
Legal Nature ◽  
History Of ◽  
Cordon Sanitaire

"Although the concept of public health is a modern one and the scientific understanding of infectious diseases and their transmissibility is less than 200 years old, even ancient and medieval societies reacted in an organized manner to the great epidemics and the threat they posed to public order and their very existence. In spite of the fact that the sources of contagious diseases were often vaguely or wrongly understood, some of the measures that these older societies began to take (the quarantine, cordon sanitaire, isolating the sick, disinfecting objects) proved effective and have been continuously perfected along the centuries. This study will attempt to discuss, using the historical method, some of the most important normative non-medical interventions in the history of epidemics that have survived to this day. Due to the legal nature of this study, we will not discuss the medical aspects of public health during pandemics, like vaccination, treatment, diagnosis or medical care. The focus of this study will be decisively European, although some passing references will be made to North America."

scholarly journals Patterns of smallpox mortality in London, England, over three centuries

PLoS Biology ◽  
2020 ◽  
Vol 18 (12) ◽  
pp. e3000506
Author(s):  
Olga Krylova ◽  
David J. D. Earn
Keyword(s):  
Public Health ◽  
Infectious Disease ◽  
Time Series ◽  
Spectral Analysis ◽  
Infectious Diseases ◽  
Health Policies ◽  
Human Populations ◽  
Public Health Policies ◽  
History Of ◽  
History Of Control

Smallpox is unique among infectious diseases in the degree to which it devastated human populations, its long history of control interventions, and the fact that it has been successfully eradicated. Mortality from smallpox in London, England was carefully documented, weekly, for nearly 300 years, providing a rare and valuable source for the study of ecology and evolution of infectious disease. We describe and analyze smallpox mortality in London from 1664 to 1930. We digitized the weekly records published in the London Bills of Mortality (LBoM) and the Registrar General’s Weekly Returns (RGWRs). We annotated the resulting time series with a sequence of historical events that might have influenced smallpox dynamics in London. We present a spectral analysis that reveals how periodicities in reported smallpox mortality changed over decades and centuries; many of these changes in epidemic patterns are correlated with changes in control interventions and public health policies. We also examine how the seasonality of reported smallpox mortality changed from the 17th to 20th centuries in London.

History of Infectious Diseases

2017 ◽  
pp. 1-23
Author(s):  
Maria Ines Zanoli Sato
Keyword(s):  
Public Health ◽  
Climate Change ◽  
Infectious Disease ◽  
Infectious Diseases ◽  
Human Development ◽  
Essential Role ◽  
Emerging Pathogens ◽  
Determining Factors ◽  
History Of

This chapter provides a review of infectious disease to date and the challenges they may present in the future. The main pandemics that have driven the history of humanity are described, from the first to be recorded in 3180 BC to more recent ones such as AIDIS, SARS and others associated with emerging pathogens. The essential role of emerging scientific specialisms (particularly microbiology, public health and sanitary engineering) to our understanding of the causes of these diseases (and how they may be better monitored, controlled and prevented) is presented. Globalization and climate change, determining factors for the ecology of infectious diseases and their emergence and re-emergence, are discussed and point to the urgent need for research to deal with these threats that continue to have a significant impact on human development and wellbeing.

scholarly journals Precision Medicine and Precision Public Health in the Era of Pathogen Next-Generation Sequencing

2019 ◽  
Vol 221 (Supplement_3) ◽  
pp. S289-S291 ◽  
Author(s):  
Mariana Leguia ◽  
Anton Vila-Sanjurjo ◽  
Patrick S G Chain ◽  
Irina Maljkovic Berry ◽  
Richard G Jarman ◽  
...  
Keyword(s):  
Public Health ◽  
Next Generation Sequencing ◽  
Infectious Diseases ◽  
Next Generation ◽  
The Past ◽  
Infectious Disease Research ◽  
History Of ◽  
Next Generation Sequencing Ngs ◽  
Generation Sequencing ◽  
Health Applications

Abstract This brief report serves as an introduction to a supplement of the Journal of Infectious Diseases entitled “Next-Generation Sequencing (NGS) Technologies to Advance Global Infectious Disease Research.” We briefly discuss the history of NGS technologies and describe how the techniques developed during the past 40 years have impacted our understanding of infectious diseases. Our focus is on the application of NGS in the context of pathogen genomics. Beyond obvious clinical and public health applications, we also discuss the challenges that still remain within this rapidly evolving field.

scholarly journals THE INTRODUCTION OF BIOTERRORISM IN MALAYSIA: A LEGAL APPROACH

2012 ◽  
Author(s):  
Rohani Abdul Rahim ◽  
Nor Anita Abdullah
Keyword(s):  
Public Health ◽  
Infectious Diseases ◽  
International Law ◽  
Legal History ◽  
Biological Agents ◽  
Structured Interviews ◽  
Real Situation ◽  
The Public ◽  
History Of ◽  
History Of International Law

The deliberate use of biological agents and the emergence of infectious diseases which can produce harm to human health and give effects to the public health and security are well recognised. A few years back, an attack of biological agents would be the most unthinkable situation to happen. However, the threat of bioterrorism is real and it is growing. It continues to be a major challenge today and the possibility of bioterrorism is undeniable as it is increasingly defined globally as ‘not if, but when’. Therefore, this paper attempts to give a brief explanation on the threat of bioterrorism as to the emergence of infectious diseases and the legal history of international law on bioterrorism. The main objective of this paper is to find out the need for bioterrorism law in Malaysian i.e. a legal approach. The study is a social legal research, which uses a qualitative approach. Thus, due to lack of materials and publications in Malaysia, in order to achieve the objectives, the methodology used was based on a semi structured interviews conducted with three respected experts in public health and security to explore the real situation in Malaysia. The authors found out that the finding of this study had established that an outbreak of infectious diseases can now be viewed as a threat that may result to bioterrorism if there is no preparation to handle it. Keywords: Bioterrorism, biological agents, infectious diseases, legal and preparedness

scholarly journals Designing the Next Generation of Vaccines: Relevance for Future Pandemics

mBio ◽  
2020 ◽  
Vol 11 (6) ◽  
pp. e02616-20
Author(s):  
Jorge Domínguez-Andrés ◽  
Reinout van Crevel ◽  
Maziar Divangahi ◽  
Mihai G. Netea
Keyword(s):  
Infectious Diseases ◽  
Immune Responses ◽  
The Elderly ◽  
Noncommunicable Diseases ◽  
Immunocompromised Patients ◽  
Annual Saving ◽  
Risk Of Infection ◽  
Medical Interventions ◽  
History Of ◽  
New Strategies

ABSTRACTThe development of vaccines is one of the greatest medical interventions in the history of global infectious diseases and has contributed to the annual saving of at least 2 to 3 million lives worldwide. However, many diseases are not preventable through currently available vaccines, and the potential of modulating the immune response during vaccination has not been fully exploited. The first golden age of vaccines was based on the germ theory and the use of live, attenuated, inactivated pathogens or toxins. New strategies and formulations (e.g., adjuvants) with an immunomodulatory capacity to enhance the protective qualities and duration of vaccines have been incompletely exploited. These strategies can prevent disease and improve protection against infectious diseases, modulate the course of some noncommunicable diseases, and increase the immune responses of patients at a high risk of infection, such as the elderly or immunocompromised patients. In this minireview, we focus on how metabolic and epigenetic modulators can amplify and enhance the function of immunity in a given vaccine. We propose the term “amplifier” for such additives, and we pose that future vaccines will have three components: antigen, adjuvant, and amplifier.

scholarly journals A morning with Louis Pasteur: a short history of the “clean hands”

2020 ◽  
Vol 36 (6) ◽  
Author(s):  
Cláudio Tadeu Daniel-Ribeiro ◽  
Marli Maria Lima
Keyword(s):  
Public Health ◽  
Hand Hygiene ◽  
Infectious Diseases ◽  
Scientific Community ◽  
Point Of View ◽  
Short History ◽  
The Public ◽  
Health History ◽  
Public Health History ◽  
History Of

Abstract: This article examines the story of Louis Pasteur from the point of view of a classic movie presented at the Weekly Seminars of the “Oswaldo Cruz Institute”, at the end of the 2017 activities. Although very old, the movie The Story of Louis Pasteur (Warner Bros., 1936) inspired spectators and gave rise to an energetic debate that led the authors to decide for publishing the comments of the Seminar Coordinator, the guest commentator and the audience. The movie communicates to the public the legacy of one of the greatest precursors of the public health history using also fictional characters. The article presents the reliable passages in Pasteur’s biography and the fictional ones, without disrespecting the production of the creators of cinematographic work. The major merit of the movie, one of the first steps towards the policy of scientific diffusion, is to disclose the importance of vaccines and hand hygiene to prevent infectious diseases. The authors argue that the film-maker impeccably captured the scientist’s tenacity in the relentless search for discoveries and Pasteur’s idea that only persistent work can lead to rewarding results, remembering that the context created by previous researchers enabled Pasteur to establish new paradigms. Finally, the authors cite movie passages illustrating realities that are still in force: (i) the inertial resistance of science to new paradigms, illustrated by the medical-scientific community opposing to simple practices proposition, such as washing hands and boiling instruments, and (ii) the excessive confidence, and even arrogance, of some specialists, instead of serenity and humility that arise from committed study and accumulated knowledge.

History of Infectious Diseases

2019 ◽  
pp. 1-18
Author(s):  
Maria Ines Zanoli Sato
Keyword(s):  
Public Health ◽  
Climate Change ◽  
Infectious Disease ◽  
Infectious Diseases ◽  
Human Development ◽  
Essential Role ◽  
Emerging Pathogens ◽  
Determining Factors ◽  
History Of

This chapter provides a review of infectious disease to date and the challenges they may present in the future. The main pandemics that have driven the history of humanity are described, from the first to be recorded in 3180 BC to more recent ones such as AIDIS, SARS and others associated with emerging pathogens. The essential role of emerging scientific specialisms (particularly microbiology, public health and sanitary engineering) to our understanding of the causes of these diseases (and how they may be better monitored, controlled and prevented) is presented. Globalization and climate change, determining factors for the ecology of infectious diseases and their emergence and re-emergence, are discussed and point to the urgent need for research to deal with these threats that continue to have a significant impact on human development and wellbeing.

scholarly journals Nalezljive bolezni sodobnega časa

2021 ◽  
pp. 259-268
Author(s):  
Zoran Simonović ◽  
Keyword(s):  
Public Health ◽  
Infectious Diseases ◽  
Global Public Health ◽  
West Nile Fever ◽  
Public Health Burden ◽  
Modern Times ◽  
Mass Gatherings ◽  
Contagious Diseases ◽  
Significant Public Health ◽  
Epidemiological Characteristics

Infectious diseases have shaped human history, and they still represent significant public health risks nowadays. As new infectious disease agents emerge, old microbes are evolving and acquiring the possibility for more effective human transmission. Some of them become resistant to medicines and spread to new geographical areas. Sometimes public health measures are implemented suboptimally, which makes spreading easier among the human population. The spread of contagious diseases is facilitated by changes in living conditions, mass gatherings, urbanization, growing international trade, and traveling. The most important infectious diseases, which we have encountered in modern times and were or are still representing global public health threats and public health burden, are malaria, HIV/AIDS, tuberculosis, influenza, infectious diarrhea, Ebola, MERS, SARS, measles, Zika, West Nile fever, Covid-19 and others. In this article, we describe some epidemiological characteristics of some of these infectious diseases.

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