Prevalence of oral cancer patients at the Pathology Anatomy Department RSUD Tasikmalaya year 2002-2007

Malignancy was included which happened in the oral cavity. Oral cavity cancer is statistically fever than other parts of a body but can to be dead. The incidence of malignancy was increased in the last 50 years throughout the world. The purpose of this research is to get distribution data about oral malignancy cases frequency at Rumah Sakit Umum Daerah/RSUD Tasikmalaya. Rumah Sakit Umum Daerah Tasikmalaya is a Referal Hospital from East Priangan region, West Java Indonesia. This is retrospective descriptive research. Samples were taken from Histopathologic form data patient at RSUD Tasikmalaya from January 2002-December 2007. The result of this study indicated that 15 cases oral malignancy cases from all samples 2943 histopathology specimen in the period. The most malignancy cases of carcinoma were squamous cell carcinoma (98%). Tongue became the most area in this cases which was 46.66%. Oral malignancy were common in men 54%. The group of ages 60-70% became the majority namely 40%. The conclusion of the research indicated that carcinoma cell squamous were became the greatest part of oral malignancy types.

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Histopathological spectrum of oral cavity lesions – A tertiary care experience

Indian Journal of Pathology and Oncology ◽

10.18231/j.ijpo.2021.071 ◽

2021 ◽

Vol 8 (3) ◽

pp. 364-368

Author(s):

Ishani Gupta ◽

Rekha Rani ◽

Jyotsna Suri

Keyword(s):

Squamous Cell Carcinoma ◽

Retrospective Study ◽

Oral Cancer ◽

Oral Cavity ◽

Cell Carcinoma ◽

Squamous Cell ◽

Tertiary Care ◽

Proper Management ◽

The World ◽

One Year

Oral cancer is one of a major health problem in some parts of the world especially in the developing countries. Oral cancer is the sixth most common cancer in the world whereas in India it is one of the most prevalent cancer. Oral cavity lesions are usually asymptomatic. Accurate diagnosis of the lesion is the first step for the proper management of patients and histopathology is considered as the gold standard. The objective is to study the different patterns of oral cavity lesions seen in a tertiary care hospital of Jammu: One year retrospective study. Post graduate department of pathology.: It was a retrospective study carried out in a tertiary care centre for a period of one year from March 2020 to Feb 2021. 148 cases of oral cavity lesions were included in this study. The parameters that were included in the study were sociodemographic data, site of the lesion, clinical features and histological diagnosis. Data collected was analysed.148 cases of oral lesions were identified during the period of study. The age of patients varied from 5 to 78years and Male to Female ratio was 2.2:1. Buccal mucosa (30%) was the most common site involved which was followed by tonsil (19%). Out of 148 cases 70 cases were malignant, 10 cases pre malignant and 21 cases were benign. Squamous cell carcinoma (33.7%) was the most common lesion present in our study. Oral cavity lesions have a vast spectrum of diseases which range from tumour like lesions to benign and malignant tumours. Our study concluded that squamous cell carcinoma was the most common malignant lesion of oral cavity. Histological typing of the lesion is important for confirmation of malignancy and it is essential for the proper management of the patient.

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Serum Cotinine Level as a Tobacco Exposure Related Biomarker in Oral Cavity Malignancy

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl4.4440 ◽

2020 ◽

Vol 11 (SPL4) ◽

pp. 2181-2187

Author(s):

Anand Guddur ◽

Shah A M ◽

Amol D Langade ◽

Shreesh A Kolekar ◽

Lahoti Jeevan ◽

...

Keyword(s):

High Risk ◽

Oral Cancer ◽

Oral Cavity ◽

Cancer Patients ◽

Oral Cavity Cancer ◽

Tobacco Exposure ◽

Serum Cotinine ◽

Cotinine Level ◽

Oral Cancer Patients ◽

Tobacco Chewing

Oral cancer has posed a challenge to us with its incidence as high as around 20% of total body cancers aim of the study was to quantify serum cotinine level as tobacco exposure-related biomarker in controls, chronic tobacco chewers (High risk for oral cavity malignancy) and oral cavity cancer patients. This was a hospital-based case-control study of 24 months duration in controls, chronic tobacco chewers and oral cancer patients. A total of 150 subjects had enrolled after meeting the inclusion & exclusion criteria. The commonest age group of oral cavity malignancy was 41 to 50 years. Males were found to be more affected than females. Tobacco chewing was the most common habits in a male patient and mishri application in female patients. In this study, 90% of patients had a history of tobacco consumption for the last ten years or more. Frequency of tobacco chewing was more in chronic tobacco chewers (30% in more than ten times a day) compared to oral cavity malignancy group (16% in more than ten times a day). The majority (more than 50%) of patients had tumour arising from the buccal mucosa, and histopathological studies revealed that 48% of patients had well-differentiated squamous cell carcinoma. Serum cotinine level in non-tobacco exposure group is less than 1 ng/mL. Conclusion- Tobacco chewing habit is a high-risk factor for oral cancer. Chronic tobacco chewers can be included in the high-risk group for oral cavity cancer. Serum cotinine level can be used as a tumour marker for oral cancer patients.

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Oral cavity squamous cell carcinoma presenting as a nasal mass in the setting of a dental implant

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-20-00392 ◽

2021 ◽

Author(s):

Alyssa Civantos ◽

Karthik Rajasekaran

Keyword(s):

Squamous Cell Carcinoma ◽

Oral Cavity ◽

Cell Carcinoma ◽

Dental Implant ◽

Squamous Cell ◽

Unusual Case ◽

Oral Cavity Cancer ◽

Nasal Mass ◽

History Of ◽

Oral Malignancy

Primary oral cavity squamous cell carcinomas can rarely occur in anatomic vicinity of a dental implant in patients with no history of prior oral malignancy or premalignancy. This typically presents as a symptomatic oral gingival lesion. We report the unusual case of a 65-year-old former-smoker female with an implant-supported upper denture who developed an isolated nasal mass on exam, found to be a squamous cell carcinoma originating from the hard palate. Although very rare, an oral cavity cancer should be taken into consideration in the differential diagnosis of a nasal cavity mass in the setting of dental implants.

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Evaluation of swallowing dysfunction in cases of locally advanced squamous cell carcinoma oral cavity pre and post treatment

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20193884 ◽

2019 ◽

Vol 5 (5) ◽

pp. 1360 ◽

Cited By ~ 1

Author(s):

Poonam Raj ◽

Devendra Kumar Gupta ◽

Sameer Samuel ◽

Sanajeet Kumar Singh

Keyword(s):

Squamous Cell Carcinoma ◽

Oral Cancer ◽

Oral Cavity ◽

Cell Carcinoma ◽

Squamous Cell ◽

Locally Advanced ◽

Post Treatment ◽

Post Surgery ◽

Swallowing Dysfunction ◽

Oral Cancer Patients

Background: Oral cancer is one of the leading causes of dysphagia worldwide and is extremely common in Indian males. Swallowing dysfunction occurs due to the disease itself, its predisposing factors like tobacco chewing or smoking and the treatment undertaken which includes surgery of the primary as well as neck dissection and the adjuvant radiotherapy or chemoradiotherapy. This study was aimed to evaluate swallowing dysfunction in patients of locally advanced squamous cell carcinoma of the oral cavity prior to treatment and post-surgery and adjuvant therapy.Methods: 30 consecutive patients of advanced oral cavity squamous cell carcinoma planned for definitive treatment at a tertiary care center were randomly selected and included in the study. Evaluation of swallowing function was carried out using a dysphagia score and FEES (functional endoscopic evaluation of swallowing) initially during work-up for surgery, then three to four weeks post-surgery and finally six to eight weeks post adjuvant therapy.Results: Results of the study revealed that swallowing dysfunctions was observed in all the timelines of the study. Smoking, larger resection and advanced tumour stage were strong risk factors for postoperative aspiration and dysphagia complications in oral cancer patients. Multi-modality treatment also increased the incidence of post treatment dysphagia.Conclusions: Subjective and objective assessment of swallowing dysfunctions have to be considered as important tools to assess dysphagia pre and post treatment in oral cancer patients to detect swallowing dysfunction especially silent aspiration to institute early intervention in terms of swallow therapy.

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Delay in the Diagnosis of Oral Malignancy : Study on Responsible Factors

Chattagram Maa-O-Shishu Hospital Medical College Journal ◽

10.3329/cmoshmcj.v19i2.50040 ◽

2020 ◽

Vol 19 (2) ◽

pp. 37-40

Author(s):

Nurul Karim Chowdhury ◽

Kyaw Khin U ◽

Ziaul Answar Chowdhury ◽

Md Abbas Uddin ◽

HS Mubarak Hossain ◽

...

Keyword(s):

Oral Cancer ◽

Health Professionals ◽

Early Detection Of Cancer ◽

Diagnostic Delay ◽

College Hospital ◽

Medical College ◽

The World ◽

Oral Cancer Patients ◽

Monetary Issue ◽

Oral Malignancy

Background : Oral malignancy is an emerging disease all over the world. Treatment failure is grave if the diagnosis is delayed in this disease which will ultimately increase the mortality rate. This is an observational sociodemographic study, done to identify the causes in diagnostic delay of the patients suffering from oral cancer. Materials and methods: The study was done with a sample size of 215 cases of oral cancer patients. This observational study was conducted from 1st August 2015 to 31st December 2016 at Upazila Health Complex, Mirsarai, Chattogram & later at ENT Department of Chittagong Medical College Hospital from 1st March 2017 to 30thApril 2018. Results: Several causes of diagnostic delay were identified. Among them, monetary issue (78%) and Ignorance or Illiteracy (69%) have been found as the most important causes. Stage of the disease, delay in referral system, tobacco use, age, gender, alternative medicine, social taboo ,distance of hospital from house etc were found the other factors delaying the diagnosis of the cancer. Conclusion: Many of the causes of delay can be preventable. The authority should establish awareness among the patients & a protocol for early detection of cancer by the health professionals. Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 37-40

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Hepatocyte Nuclear Factor 4 Alpha Overexpression Confers Resistance to Radiation in a Human Oral Cavity Squamous Cell Carcinoma Cell Line

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2017.12.085 ◽

2018 ◽

Vol 100 (5) ◽

pp. 1339

Author(s):

J.D. Smith ◽

C. Matovina ◽

S.K. Foltin ◽

A.C. Birkeland ◽

J.C. Brenner

Keyword(s):

Squamous Cell Carcinoma ◽

Oral Cavity ◽

Cell Carcinoma ◽

Cell Line ◽

Squamous Cell ◽

Carcinoma Cell ◽

Nuclear Factor ◽

Hepatocyte Nuclear Factor ◽

Squamous Cell Carcinoma Cell ◽

Hepatocyte Nuclear Factor 4

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The incidence of oral squamous cell carcinoma (OSCC) and its relationship with orofacial pain in oral cancer patients in West Java Province, Indonesia

Journal of Oral and Maxillofacial Surgery Medicine and Pathology ◽

10.1016/j.ajoms.2016.09.001 ◽

2017 ◽

Vol 29 (1) ◽

pp. 29-32 ◽

Cited By ~ 3

Author(s):

Tantry Maulina ◽

Aulia Iskandarsyah ◽

Andri Hardianto ◽

Endang Sjamsudin ◽

Mantra Nandini ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Oral Cancer ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Cancer Patients ◽

Squamous Cell ◽

Orofacial Pain ◽

West Java ◽

Oral Cancer Patients

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Exhaled breath and oral cavity VOCs as potential biomarkers in oral cancer patients

Journal of Breath Research ◽

10.1088/1752-7163/aa5e76 ◽

2017 ◽

Vol 11 (1) ◽

pp. 016015 ◽

Cited By ~ 20

Author(s):

M Bouza ◽

J Gonzalez-Soto ◽

R Pereiro ◽

J C de Vicente ◽

A Sanz-Medel

Keyword(s):

Oral Cancer ◽

Oral Cavity ◽

Cancer Patients ◽

Exhaled Breath ◽

Oral Cancer Patients ◽

Potential Biomarkers

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Adjunctive Therapy in Oral Cancer

Oral and Maxillofacial Surgery for the Clinician ◽

10.1007/978-981-15-1346-6_84 ◽

2021 ◽

pp. 1903-1913

Author(s):

Amit Dhawan

Keyword(s):

Squamous Cell Carcinoma ◽

Oral Cancer ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Cancer Patients ◽

Squamous Cell ◽

Adjunctive Therapy ◽

Early Stage ◽

Advanced Stage ◽

Oral Cancer Patients

AbstractOral squamous cell carcinoma is the third most common cancer in Indian subcontinent affecting people with lower socioeconomic status. Due to inadequate screening facilities and lack of awareness among individuals most of the oral cancer cases are detected at an advanced stage. As early stage oral squamous cell carcinoma patients can be treated with single modality treatment (surgery or radical radiotherapy), multimodality regimen (surgery followed by concurrent chemoradiation) is adopted for high risk advanced stage cancers with multiple adverse features like extra nodal extension, lymphovascular invasion and perineural spread. The chapter outlines the principles of adjunctive therapy in oral cancer patients with special reference to different techniques, indications of radiotherapy and role of chemotherapeutic regimes in improving the overall survival of advanced stage oral cancer patients.

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