Carboxymethyl cellulose synthesis from wheat straw and physiological effects as food additive on some haematological and biochemical parameters of male mice.

2018 ◽  
Vol 8 (4) ◽  
Keyword(s):  
Wheat Straw ◽  
Carboxymethyl Cellulose ◽  
Biochemical Parameters ◽  
Food Additive ◽  
Cellulose Synthesis ◽  
Physiological Effects ◽  
Male Mice

scholarly journals CARBOXYMETHYL CELLULOSE SYNTHESIS FROM TREATED OIL PALM EMPTY FRUIT BUNCH USING IONIC LIQUID AND HYDROGEN PEROXIDE

2021 ◽  
Vol 11 (4) ◽  
pp. 80-88
Author(s):  
Muzakkir Mohammad Zainol ◽  
Nurul Suhada Ab Rasid ◽  
Mohd Asmadi ◽  
Nor Aishah Saidina Amin
Keyword(s):  
Hydrogen Peroxide ◽  
Ionic Liquid ◽  
Carboxymethyl Cellulose ◽  
Proton Nuclear Magnetic Resonance ◽  
Sodium Chlorite ◽  
Cellulose Synthesis ◽  
Empty Fruit Bunch ◽  
Acid Pretreatment ◽  
Ionic Liquid Pretreatment ◽  
Magnetic Resonance Scanning

The synthesis of carboxymethyl cellulose (CMC) generally uses isolated crude cellulose with alkaline or acid pretreatment followed by bleaching with sodium chlorite. In this study, the simple [BMIM][Cl] ionic liquid was used as a solvent in the pretreatment process before conduct the bleaching process with hydrogen peroxide (H2O2) to isolate cellulose from empty fruit bunch (EFB) for further synthesis of CMC. The isolated crude EFB cellulose obtained was converted to CMC by adding 30 wt.% NaOH and various concentrations of sodium monochloroacetic acid (SMCA) at 55 °C for 3 h. The effects of SMCA concentration on the degree of substitution (DS) and CMC yield were investigated. The physicochemical properties of the CMC products were characterized using proton nuclear magnetic resonance, scanning electron microscope-energy dispersive spectrometry, X-ray diffraction, and thermogravimetric analysis. Based on the results, CMC was demonstrated to be synthesized using ionic liquid pretreatment with H2O2 bleaching. Carboxymethyl cellulose synthesized in this study showed a high DS of 0.82. The CMC synthesized from EFB cellulose through ionic liquid pretreatment presented good chemical and physical properties as that reported in other studies.

scholarly journals Antifungal Activity and Acute and Repeated-Dose Toxicity Study of Geranyl Cinnamate Ester in Mice

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Micheli Zanetti ◽  
Mikaela Scatolin ◽  
Amanda Rebonatto Oltramari ◽  
Maria Luiza Lima da Costa Lopes ◽  
Rubieli Carla Frezza Zeferino ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Acute Toxicity ◽  
Biochemical Parameters ◽  
Body Weight Gain ◽  
The Body ◽  
Repeated Dose ◽  
Male Mice ◽  
Minimum Concentration ◽  
Repeated Dose Toxicity ◽  
Hematological And Biochemical Parameters

In the present study, the antifungal activity and toxicity of the geranyl cinnamate ester (GCE) were investigated. The GCE showed antifungal activity at a minimum concentration of 0.16 μL/mL against Candida albicans and at concentrations greater than 2.5 μL/mL against Aspergillus niger. In acute toxicity studies, the administration of GCE (2.000 mg/kg) affected the body weight gain and food intake but did not induce the mortality of the animals studied. After the investigation of repeated-dose toxicity of GCE at 2 and 4 mg/kg, the hematological and biochemical parameters were changed. In addition, the adrenal weight of male mice treated with GCE at 4 mg/kg was affected. In conclusion, according to the Organization for Economic Cooperation and Development (OECD) acute toxicity parameters, the geranyl cinnamate ester can be classified into safety category number 5. The results of this study suggested that the geranyl cinnamate ester may be a source of natural antifungals.

Comparative Study of Carboxymethyl Cellulose Synthesis from Selected Kenyan Biomass

2016 ◽  
Vol 17 (4) ◽  
pp. 1-8 ◽  
Author(s):  
P Kimani ◽  
P Kareru ◽  
S Madivoli ◽  
P Kairigo ◽  
E Maina ◽  
...  
Keyword(s):  
Comparative Study ◽  
Carboxymethyl Cellulose ◽  
Cellulose Synthesis

Water content quantification by FTIR in carboxymethyl cellulose food additive

2021 ◽  
pp. 1-7
Author(s):  
Marco Consumi ◽  
Gemma Leone ◽  
Gabriella Tamasi ◽  
Agnese Magnani
Keyword(s):  
Water Content ◽  
Carboxymethyl Cellulose ◽  
Food Additive

scholarly journals Study of the Health Effects of Red Beet Juice and Asorubine Food Dyes Used in Feeding and Watering of the Animals for Experience

2019 ◽  
Vol 70 (5) ◽  
pp. 1569-1574
Author(s):  
Mihaela Claudia Spataru ◽  
Constantin Spataru ◽  
Carmen Solcan ◽  
Andrei Cristian Gradinaru ◽  
Raluca Elena Donosa ◽  
...  
Keyword(s):  
Weight Gain ◽  
Health Effects ◽  
Food Additive ◽  
The Other ◽  
Male Mice ◽  
Human Food ◽  
Red Beet ◽  
Food Dyes ◽  
The Common ◽  
Over Time

The paper aims to investigate the health effects of red beet juice and asorubine food dyes used in mice feeding and watering, considering the common use of these food colorants as additives in human food. The investigations related to this study were performed over a 3-month period, using 30 male mice which were divided into three batches 10 mice each. The red beet juice has given to nutrients and waters a better organoleptic quality so, the weight gain of mice was registered. The same, the increase in weight of mice receiving asorubine was higher. The anatomo- and histo-pathological examinations of mice that received red beet juice do not indicate a clear toxicity of this dye. However, red beet juice should not be consumed daily and in large quantities. On the other hand, injuries induced by asorubine in liver and kidneys may be characteristic for toxicity. So, the use and consumption of asorubine as a food additive should be undertaken with caution; although this compound is more stable and does not oxidize over time, if possible replace it with natural dyes.

scholarly journals ANTITHROMBOTIC EFFECT OF TRIGONELLA FOENUM-GRACEUM ON COLLAGEN/ EPINEPHRINE-INDUCED THROMBOEMBOLISM IN MICE

2018 ◽  
Vol 10 (1) ◽  
pp. 56 ◽  
Author(s):  
Fadlina Chany Saputri ◽  
Astari Rachma Nityasa
Keyword(s):  
Survival Rate ◽  
Carboxymethyl Cellulose ◽  
Survival Rates ◽  
Study Groups ◽  
Male Mice ◽  
Antithrombotic Effect ◽  
Antithrombotic Activity ◽  
Tail Vein ◽  
Negative Controls ◽  
Positive Controls

Objective: This study aimed to further investigate the antiplatelet and antithrombotic activities of Trigonella foenum-graceum (TFG) in vivo.Methods: Male mice were divided into two experimental groups (bleeding duration and survival rate). The study groups comprised vehicle controls(administered carboxymethyl cellulose [CMC]), negative controls (administered CMC), positive controls (administered aspirin), and experimentaltreatment groups (administered TFG extract at three doses). Bleeding duration was assessed by excising the tail vein. Survival rate was determinedby inducing thrombosis through intravenous collagen/epinephrine administration.Results: In mice treated with TFG extract for 7 days, bleeding duration was significantly increased compared with that in controls (p<0.05). Moreover,mice treated with TFG showed increased survival rates compared with negative controls.Conclusion: TFG extract showed antithrombotic activity in mice by significantly increasing bleeding duration and survival rate.

scholarly journals Short-Term Physiological Effects of a Very Low-Calorie Ketogenic Diet: Effects on Adiponectin Levels and Inflammatory States

2020 ◽  
Vol 21 (9) ◽  
pp. 3228 ◽  
Author(s):  
Vincenzo Monda ◽  
Rita Polito ◽  
Annarita Lovino ◽  
Antonio Finaldi ◽  
Anna Valenzano ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Caloric Restriction ◽  
Ketogenic Diet ◽  
Biochemical Parameters ◽  
Inflammatory Diseases ◽  
Physiological Effects ◽  
Short Term ◽  
Low Calorie ◽  
Before And After ◽  
Obese Subjects

Adipose tissue is a multifunctional organ involved in many physiological and metabolic processes through the production of adipokines and, in particular, adiponectin. Caloric restriction is one of the most important strategies against obesity today. The very low-calorie ketogenic diet (VLCKD) represents a type of caloric restriction with very or extremely low daily food energy consumption. This study aimed to investigate the physiological effects of a VLCKD on anthropometric and biochemical parameters such as adiponectin levels, as well as analyzing oligomeric profiles and cytokine serum levels in obese subjects before and after a VLCKD. Twenty obese subjects were enrolled. At baseline and after eight weeks of intervention, anthropometric and biochemical parameters, such as adiponectin levels, were recorded. Our findings showed a significant change in the anthropometric and biochemical parameters of these obese subjects before and after a VLCKD. We found a negative correlation between adiponectin and lipid profile, visceral adipose tissue (VAT), C-reactive protein (CRP), and pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α), which confirmed the important involvement of adiponectin in metabolic and inflammatory diseases. We demonstrated the beneficial short-term effects of a VLCKD not only in the treatment of obesity but also in the establishment of obesity-correlated diseases.

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