Karakteristik Klinis Pasien Trombosis Sinus Venosus Serebral (TSVS) di Ruang Rawat Inap Neurologi Rumah Sakit Hasan Sadikin Bandung

Latar Belakang dan Tujuan: Trombosis sinus venosus serebral (TSVS) merupakan penyakit akibat oklusi struktur vena intrakranial, termasuk sinus serebral, vena korteks, dan bagian proksimal vena jugularis. Keterlambatan diagnosis dan terapi dapat mengakibatkan terjadinya komplikasi seperti infark berdarah bahkan kematian.Tujuan penelitian ini adalah untuk mengetahui karakteristik klinis pasien TSVS yang diagnosisnya telah dikonfirmasi melalui pemeriksaan DSA. Metode: Penelitian ini bersifat deskriptif observasional retrospektif. Pada pasien yang telah didiagnosis TSVS di Bagian Neurologi Rumah Sakit Hasan Sadikin Bandung periode Juni 2015 sampai November 2017.Hasil: Terdapat 33 subjek dengan rentang usia 40-49 tahun (24,2%) dan mayoritas adalah perempuan sebanyak 22 orang (66,7%). Faktor resiko terbanyak adalah infeksi 8 orang (24,2%), dan kondisi protrombotik sebanyak 6 orang (18,2%). Gejala klinis terbanyak adalah nyeri kepala yaitu 27 orang (81,8%). Lokasi sinus yang tersering mengalami trombosis adalah sinus transversus pada 28 orang dengan gejala mayoritas nyeri kepala. Kadar D-Dimer ditemukan meningkat dengan rata-rata 1,21 mg/L.Simpulan: Pasien TSVS terjadi pada perempuan dengan rentang usia dekade pertengahan dan faktor resiko terbanyak adalah infeksi. Nyeri kepala merupakan gejala paling sering. Lokasi trombosis mayoritas terjadi pada sinus transversus dan ditemukan peningkatan D-Dimer. Clinical Characteristics of Cerebral Venous Sinus Thrombosis (CVST) Patients in Neurology Ward Hasan Sadikin General Hospital BandungAbstractBackground and Objective: CVST is an entity caused by intracranial vein, including cerebral sinuses, cortical vein and proximal part of the jugular vein. A delay in diagnosing and treating can result in brain infarct with hemorrhagic transformation, even death. The goal of this study is to learn the clinical characteristics of patients with CVST that had been confirmed by DSA.Method: This was a retrospective observational descriptive study and subjects were hospitalized patients which had been diagnosed CVST in Neurology ward Hasan Sadikin General Hospital from June 2015 to November 2017.Results: there was 33 subjects with most (22 patient/66.7%) being women between 40-49 years old. In this study the most frequently found risk factor was infection in 8 subjects (24.2%), prothrombotic conditions in 6 subjects (18.2%). The clinical manifestations were mainly headache in 27 subjects (81,8%). The sinus most often involved was the transverse sinus (28 subjects) with the clinical manifestation being headache. D-dimer levels were also increased with mean 1.21 mg/dl.Conclusion: CVST patients are mostly in women at the midle age of decade, with infection being the most frequent risk. Headache was the most frequent clinical manifestation. Location of thrombosis were more often found on the transverse sinus and D-Dimer level was increased.

Download Full-text

Clinical characteristics and risk factors of Fulminant Mycoplasma pneumoniae pneumonia in children

10.21203/rs.2.22954/v1 ◽

2020 ◽

Author(s):

yaoyao ling ◽

Tongqiang Zhang ◽

Zhenli Zhu ◽

Jiao Tian ◽

yongsheng xu ◽

...

Keyword(s):

Risk Factors ◽

Pleural Effusion ◽

Mycoplasma Pneumoniae ◽

Clinical Characteristics ◽

Laboratory Data ◽

Clinical Manifestations ◽

Multivariate Logistic Regression Analysis ◽

Radiological Findings ◽

Mycoplasma Pneumoniae Pneumonia ◽

D Dimer

Abstract BACKGROUND: Analyze the clinical characteristics of Fulminant Mycoplasma pneumoniae pneumonia (FMPP), and explore the related factors predicting FMPP. METHODS: A retrospective case-control study was performed on 345 children with Mycoplasma pneumoniae pneumonia (MPP) hospitalized in our Hospital from January 2017 to June 2019. The clinical features, laboratory data and radiological findings were compared between the FMPP group, refractory Mycoplasma pneumoniae pneumonia (RMPP)group and general Mycoplasma pneumoniae pneumonia (GMPP) group. RESULTS: FMPP patients (n=69) had more severe presentations, higher incidence of extra-pulmonary complications and more serious radiological findings(P<0.05). And the days of fever and the days in hospital were longer, and FMPP patients also need more complicated treatments(P<0.05). Meanwhile, the levels of white blood cell count(WBC) ,C-reactive protein(CRP), lactic dehydrogenase (LDH), interleukin (IL)-6,ferritin, D-dimer, fibrinogen(FG),alanine aminotransferase(ALT) and the percentage of neutrophils in the FMPP group were significantly higher than those in the RMPP group and the GMPP group (both P<0.05). In ROC curve analysis, the percentage of neutrophils, WBC, CRP, LDH, IL-6, ferritin, D-dimer and ALT were contributed to identify FMPP patients. Multivariate logistic regression analysis showed that ferritin>174.15 ng/mL, IL-6>25.475pg/ml and pleural effusion had significant predictive effects on the early diagnosis of FMPP (P<0.01). Conclusion: FMPP patients presented more serious clinical manifestations. Ferritin>174.15 ng/mL, IL-6>25.475pg/ml and pleural effusion were high risk factors for FMPP.

Download Full-text

Clinical Manifestation and Laboratory Finding of Sclerosis Systemic Patient in Dr. Hasan Sadikin General Hospital Bandung : A Descriptive Quantitative Study

Indonesian Journal of Rheumatology ◽

10.37275/ijr.v10i1.93 ◽

2018 ◽

Vol 10 (1) ◽

Author(s):

Annisa Meivira Budiman ◽

Sumartini Dewi ◽

Marietta Shanti Prananta

Keyword(s):

Systemic Sclerosis ◽

General Hospital ◽

Clinical Manifestation ◽

Clinical Symptoms ◽

Laboratory Finding ◽

Renal Involvement ◽

Clinical Manifestations ◽

Laboratory Findings ◽

Rheumatology Clinic ◽

Quantitative Design

Background Systemic sclerosis is a chronic progressive multisystem autoimmune disease in connective tissue, characterized by its heterogeneous clinical manifestation. The purpose of this study is to give information regarding clinical manifestations and laboratory findings of systemic sclerosis patients to establish diagnosis of disease. Methods This study was conducted using descriptive quantitative design in September−October 2016. Data was collected from medical records of patients visiting Rheumatology Clinic Dr. Hasan Sadikin General Hospital from 1 July 2015−30 June 2016 using total sampling method. The collected data were expected to comprise patient’s clinical manifestation and laboratory finding. Results Most of patients had cutaneous 57 (100.0%) and musculoskeletal 40 (70.2%) involvement. Some of the disease manifestations were Raynaud’s phenomenon 38 (66.7%), fingertip lesion 33 (57.9%), stiffness in skin 34 (59.6%), and arthalgia 29 (50.9%). Gastrointestinal involvements were present in 29 (50.9%) patients. Renal involvement were determined from urinalysis result showed proteinuria 10 (17.5%) and hematuria 8 (14.0%), found in 24 (42.1%) patients, while pulmonary and cardiac involvements were found in 30 (52.6%) patients, acknowledged from clinical symptoms such as dyspnea 12 (21.1%). Identification of autoantibodies was found in 12 (21.1%) patients, with 10 (17.5%) patients had reactive ANA and 3 (3.5%) had positive anti-Scl70. Conclusion Most of systemic sclerosis patients had cutaneous involvement. Renal, pulmonary, and cardiac involvement were concluded based on laboratory findings. Keywords: Systemic sclerosis, clinical manifestation, laboratory finding

Download Full-text

SARS-Cov-2: Epidemiological characteristics, clinical characteristics, diagnosis and prevention: A review of current knowledge

Srpski medicinski casopis Lekarske komore ◽

10.5937/smclk2-30845 ◽

2021 ◽

Vol 2 (2) ◽

pp. 16-22

Author(s):

Marina Fišeković-Kremić ◽

Snežana Stojanović-Ristić

Keyword(s):

Clinical Manifestation ◽

Clinical Characteristics ◽

Current Knowledge ◽

Nasal Congestion ◽

Clinical Manifestations ◽

Diagnostic Procedures ◽

X Rays ◽

Runny Nose ◽

Biochemical Analyses ◽

Epidemiological Characteristics

The SARS-Cov-2 disease appeared in December 2019, when the new coronavirus was confirmed to be the cause of the disease. The objective of this article is to summarize previous research on the epidemiological characteristics, etiology, clinical characteristics, diagnosis, prevention, and control of the new SARS-Cov-2 infection. The SARS-Cov-2 virus belongs to the group of betacoronaviruses, which are single-stranded RNA viruses. The envelope has a crucial role in the pathogenicity of the virus. A viral infection can cause an excessive immune response in the patient, which is labeled as a "cytokine storm," and whose effect is extensive tissue damage. Three main routes of the transmission of the virus are: droplets, direct contact, aerosol. The incubation period is considered to be 1-14 days. The clinical manifestation ranges from asymptomatic, mild, to severe, and some cases end in death. The main clinical manifestations include fever, cough, and shortness of breath. Nasal congestion, a runny nose, a sore throat, headache, myalgia, diarrhea, loss of the sense of taste and/or smell have also been reported. The diagnostic procedures are the following: clinical manifestation, chest X-rays, biochemical analyses, epidemiological anamnesis. A positive nasopharyngeal or oropharyngeal swab (Ag test, and/or reverse transcription polymerase chain reaction (RT-PCR)) is used for etiological diagnosis. The SARS-Cov-2 infection has affected a large number of people and countries around the world. The application of preventive measures, early identification of infected persons, their isolation , and vaccination are currently the most effective mode in the battle against this virus. After the conclusion of the pandemic, it will be possible to estimate the health, social and economic impact of the virus.

Download Full-text

Clinical Characteristics and Management of Cerebral Venous Sinus Thrombosis in Patients With Antiphospholipid Syndrome: A Single-Center Retrospective Study

Clinical and Applied Thrombosis/Hemostasis ◽

10.1177/1076029621999104 ◽

2021 ◽

Vol 27 ◽

pp. 107602962199910

Author(s):

Huixin Shen ◽

Xiaoqin Huang ◽

Chunqiu Fan

Keyword(s):

Antiphospholipid Syndrome ◽

Endovascular Therapy ◽

Clinical Characteristics ◽

Sinus Thrombosis ◽

Transverse Sinus ◽

Cerebral Venous Sinus Thrombosis ◽

Good Prognosis ◽

Venous Sinus ◽

Initial Manifestation ◽

Venous Sinus Thrombosis

Antiphospholipid syndrome (APS) with cerebral venous sinus thrombosis (CVST) is a relatively rare phenomenon, and this observational study aimed to investigate the clinical characteristics of APS patients complicated with CVST. We retrospectively investigated the clinical characteristics of CVST events in APS and compared differential characteristics and associated factors between APS patients with and without CVST. Twenty-one CVST patients with APS were enrolled including 14 females (9.4%) and 7 males (5.8%). The median age and disease duration at onset of CVST was 33 years (IQR 28-48) old and 1.3 months (IQR 0.7-4), respectively. Among APS patients with CVST, 12 (57.1%) cases presented with neurologic symptoms of CVST as the initial manifestation. Onset of CVST was mainly chronic (52.4%). Headache (90.5%) was the most common neurological symptom. The common locations of CVST were transverse sinus (76.2%) and superior sagittal sinus (57.1%), with more frequently (76.2%) dual or multiple sinuses involved. All patients with CVST were treated with anticoagulant, and 5 (23.8%) patients received endovascular therapy. Sixteen (84.2%) patients had good outcomes and 3 (15.8%) patients died at last follow-up. There were no significant differences ( P > 0.05) between two groups in the analysis of related APS indicators. There were no significant differences ( P > 0.05) between two groups in the analysis of related APS indicators. Although APS complicated with CVST is rare and predominately chronic developed. The evaluation of CVST should be performed for APS patients with intracranial hypertension syndrome. The routine screening of antiphospholipid antibodies (aPLs) is highly recommended in unexplained CVST patients. Most CVST patients with APS will have a good prognosis after treatment, and endovascular therapy is an alternative treatment.

Download Full-text

Clinical Characteristics of Behçet Disease in an Egyptian Cohort

QJM ◽

10.1093/qjmed/hcab100.100 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Hanan Mohamed Farouk ◽

Tarek A El-Maamoun ◽

Samah A Elbakry ◽

Maryam Ahmed Abdul Rahman ◽

Nermeen Samy ◽

...

Keyword(s):

Clinical Characteristics ◽

Sinus Thrombosis ◽

Clinical Manifestations ◽

Behçet Disease ◽

Ocular Involvement ◽

Behcet Disease ◽

University Hospitals ◽

Female Ratio ◽

Male Predominance ◽

Pathergy Test

Abstract Aim of the work To study the clinical characteristics of Behcet’s disease (BD) in Egyptian patients. Patients and methods 150 BD patients were recruited from the Rheumatology and Internal medicine Department, Ain Shams University Hospitals. Demographic and clinical data were collected. Disease activity was assessed using Behcet Disease Current Activity Form (BDCAF). Results 150 BD patients were included in this study. Their ages were 34.05 ± 9.28 years (14 – 66 years) and with disease duration range (1–20 years). There were 116 males (77.3%)and 34 females (22.7%), with male to female ratio of 3.4:1. The BDCAF was 4.44 ± 1.97 (2–10). The frequency of the clinical manifestations was oral ulcers in 86.7%, followed by genital ulcers in 82.0%, ocular involvement in 68.7%, vascular affection in 58.7%, articular manifestations in 32.7%, pathergy test was positive in 28.0%, skin manifestations in 26.0% (pustular lesions, folicilitis,erythema nodosum and pyoderma gangrenosum), neurological in 25.3% in the form of (CNS infarction in 12.7%,vasculitis in 6.7%, Cerebral sinus thrombosis in 4.0% and Seizures in 2.0%) and gastrointestinal in 7.3% in the form of (nausea, vomiting and abdominal pain). Conclusion In Egypt, there is a male predominance in BD patients as other areas in worldwide countries. The clinical characteristics are comparable to other studies. However, in Egypt the gastrointestinal manifestations showed the lowest recorded frequency

Download Full-text

Correlation between the imaging manifestations of cerebellar infarction and the clinical characteristics of patients: a retrospective analysis

10.21203/rs.3.rs-248783/v1 ◽

2021 ◽

Author(s):

Lai Wei ◽

Kangwei Zhang ◽

Jinqian Meng ◽

Jiong Ni ◽

Peijun Wang

Keyword(s):

Clinical Characteristics ◽

Clinical Manifestations ◽

Cerebellar Infarction ◽

Serum Concentrations ◽

Nihss Score ◽

Cerebellar Artery ◽

Underlying Causes ◽

Toast Classification ◽

Absolute Advantage ◽

D Dimer

Abstract Background The aim of this study was to analyze the correlation between the imaging manifestations of cerebellar infarction and the clinical characteristics of patients. Methods A total of 83 patients with acute cerebellar infarction were included in this analysis. The NIHSS score, TOAST classification, CT and MRI examinations and serum laboratory tests were performed. The statistics of the data were carried out through descriptive statistics, T test and analysis of variance. Results Hyperlipidemia (66.3%), hypertension (77.1%) and carotid atherosclerosis (97.6%) were the main underlying causes of cerebellar infarction. Ataxia (67.5%) and brainstem syndrome (60.2%) were main clinical manifestations. Patients with NIHSS score ≤ 5 accounted for the majority (87.9%) and SAO (43.3%) and LAA (50.6%) were the main TOAST classifications. The cerebellar infarction caused by obstruction of SCA accounted for the majority (69.9%) and there was no statistical difference in the detection ability of CTA and MRA (P > 0.05). The incidence of left hemisphere cerebellar infarction was the highest (56.7%) and MRI showed an absolute advantage in showing the area of cerebellar infarction compared with CT (P < 0.001). The serum concentrations of D-dimer, LDL, and triglycerides were higher in patients with high NIHSS scores than in those with low scores (P < 0.05), while the serum HDL levels were just the opposite (P < 0.05). The serum D-dimer concentrations in patients classified as CE by TOAST were higher than that in patients classified as LAA and SAO (P < 0.05), while the serum concentrations of LDL were just the opposite (P < 0.05). The lesion sizes of cerebellar infarction were negatively related to the patient's serum HDL concentrations (P < 0.05) but it positively correlated with the NIHSS scores (P < 0.05). The patients classified as LAA had larger lesion sizes of cerebellar infarction than those classified as SAO and CE (P < 0.001). Conclusions CTA and MRA are comparable in showing the stenosis and obstruction of the cerebellar artery. However, MRI has an absolute advantage in showing the area of cerebellar infarction. The serum concentrations of D-dimer, HDL, LDL, and triglycerides are correlated with the patient’s NIHSS scores, TOAST classification and infarct sizes, which are helpful in evaluating the condition of the disease.

Download Full-text

Cerebral Sinus Thrombosis Secondary to SARS-CoV-2 Infection

Case Reports in Neurological Medicine ◽

10.1155/2021/6640368 ◽

2021 ◽

Vol 2021 ◽

pp. 1-5

Author(s):

Mojtaba Khazaei ◽

Kiana Karimi ◽

Parinaz Sedighi ◽

Salman Khazaei

Keyword(s):

Sinus Thrombosis ◽

Neurological Complications ◽

Transverse Sinus ◽

Cerebral Vessel ◽

Respiratory Problems ◽

Cortical Vein ◽

Vein Thrombosis ◽

Cortical Vein Thrombosis ◽

Level Of Consciousness ◽

Good General Condition

Coronavirus disease-19 (COVID‐19) is a novel infectious disease and every day we are learning more about its various clinical features and complications. Different studies during the pandemic have shown various neurological manifestations secondary to the infection such as stroke due to cerebral vessel thrombosis. Herein, we presented a 57-year-old man admitted to our hospital with gradual headache, seizure, and decreasing level of consciousness. Three weeks earlier, he was diagnosed with COVID-19 and mild to moderate respiratory problems. Decreased level of consciousness made physicians intubate the patient and initiate mechanical ventilation in the intensive care unit (ICU). Treatment was initiated with phenytoin. Brain CT scan showed right transverse sinus and cortical vein thrombosis with subarachnoid hemorrhage. He received successful anticoagulant therapy, with further improvement in oxygenation, and discharged with a good general condition. This case is important because several neurological complications of COVID-19 should be noticed and managed by appropriate treatment according to the patient’s condition.

Download Full-text

D-Dimer Level with Cerebral Venous Sinus Thrombosis (CVST) Occurrence Using Digital Subtraction Angiography (DSA)

Global Medical & Health Communication (GMHC) ◽

10.29313/gmhc.v7i3.5341 ◽

2019 ◽

Vol 7 (3) ◽

Author(s):

Afdi Arahim Putra ◽

Eppy Buchori ◽

Hilman Hilman ◽

Lisda Amalia

Keyword(s):

Digital Subtraction Angiography ◽

General Hospital ◽

Clinical Symptoms ◽

Sinus Thrombosis ◽

Cerebral Venous Sinus Thrombosis ◽

Venous Sinus ◽

Digital Subtraction ◽

Research Subjects ◽

Venous Sinus Thrombosis ◽

D Dimer

Cerebral venous sinus thrombosis (CVST) is a cerebrovascular disease in the form of occlusion due to thrombus in the venous and cerebral sinuses. It rarely occurs and has varied clinical symptoms and radiological features and challenging to diagnose. D-dimer used as a diagnostic marker for cases of venous thromboembolism, with a sensitivity of around 90–92%. However, the specificity is not too high (70–73%) because it can also increase in other conditions. Digital subtraction angiography (DSA) is a gold standard examination to establish the diagnosis of CVST. The purpose of this study was to determine the relationship between the D-dimer level and CVST using DSA at Dr. Hasan Sadikin General Hospital in Bandung. This study used an observational analytic method with a case-control study design using retrospective data from medical records at Dr. Hasan Sadikin General Hospital in January 2017–August 2019. The research subjects divided into two groups, namely the high D-dimer levels and the normal/low D-dimer level. Forty people meet the inclusion criteria, ages averaging from 44.77±14.40 years, and consists of 9 male patients (22%) and 31 women patients (78%). For normal/low D-dimer levels 20 patients (50%) and high D-dimer levels 20 patients (50%). Statistical test results measuring D-dimer and CVST levels found a significant relationship (p<0.05). In conclusion, there is a relationship between D-dimer levels with CVST events that have been done by DSA. The higher the D-dimer level, the higher the suspicion of CVST. KADAR D-DIMER DENGAN KEJADIAN CEREBRAL VENOUS SINUS THROMBOSIS (CVST) MENGGUNAKAN DIGITAL SUBTRACTION ANGIOGRAPHY (DSA)Penyakit cerebral venous sinus thrombosis (CVST) merupakan penyakit serebrovaskular berupa oklusi akibat trombus di saluran vena dan sinus serebral yang jarang terjadi dengan gejala klinis dan gambaran radiologis yang bervariasi, serta sangat sulit untuk didiagnosis. D-dimer dapat dijadikan sebagai penanda diagnostik bagi kasus-kasus tromboembolisme vena dengan sensitivitas 90–92%, namun spesifisitasnya tidak terlalu tinggi (70–73%) karena dapat juga meningkat pada kondisi lain. Digital subtraction angiography (DSA) merupakan pemeriksaan baku emas untuk menegakkan diagnosis CVST. Tujuan penelitian ini mengetahui hubungan antara kadar D-dimer dan CVST menggunakan DSA di RSUP Dr. Hasan Sadikin Bandung. Penelitian ini merupakan observasional analitik dengan rancangan kasus kontrol menggunakan data retrospektif dari rekam medis di RSUP Dr. Hasan Sadikin Bandung pada bulan Januari 2017–Agustus 2019. Subjek penelitian dibagi menjadi 2 kelompok, yaitu kelompok D-dimer tinggi dan kelompok D-dimer normal/rendah. Hasil penelitian didapat 40 orang yang memenuhi kriteria inklusi, usia rerata 44,77±14,40 tahun yang terdiri atas pasien laki-laki 9 orang (22%) dan perempuan 31 orang (78%). Untuk kadar D-dimer kategori normal/rendah 20 orang (50%) dan tinggi 20 orang (50%). Hasil uji statistik mengukur kadar D-dimer dan CVST didapatkan hubungan yang bermakna (p<0.05). Simpulan, terdapat hubungan antara kadar D-dimer dan kejadian CVST yang telah dilakukan DSA. Semakin tinggi kadar D-dimer, semakin tinggi kecurigaan kejadian CVST.

Download Full-text

Clinical Characteristics of Venous Thromboembolism in COVID-19 Patients Admitted to intensive care unit

10.21203/rs.3.rs-326723/v1 ◽

2021 ◽

Author(s):

Mohamed Mosaad Abdelrahman ◽

Mohamed Abdelgwad Habeb ◽

Mohamed Abderahman Ali ◽

Mohamed Farouk Ismael ◽

Elmour Abdelrahman Ibraheem

Keyword(s):

Pulmonary Embolism ◽

Venous Thromboembolism ◽

Clinical Characteristics ◽

Sinus Thrombosis ◽

Massive Pulmonary Embolism ◽

Significant Elevation ◽

Recorded Data ◽

Risk Predictors ◽

D Dimer ◽

Morbid Conditions

Abstract Introduction: COVID-19 infection was associated with many morbid conditions, one of which is venous thromboembolism; however, this is varied in incidence and clinical characteristics, with no known definite risk predictors.Aim: To identify the incidence, clinical characteristics, and risks and outcome of venous thromboembolism in COVID-19 patients.Methods: a retrospective cohort study comparing the recorded data for two groups of patients with confirmed COVID-19 infection and admitted to the ICU in 6 months duration.Results: the incidence of venous thromboembolism was 30%, where pulmonary embolism (PE) alone was the most frequent type (68.2%), followed by, DVT with PE (15.1%), DVT alone (12.1%), cavernous sinus thrombosis alone CST (3%) and the least frequency was CST with renal artery thrombi (1.5%). Smoking and malignancy were more frequent in VTE group with more statistically significant elevation of D dimer. the pulmonary embolism was lobar in the majority of our patients (69.6%), followed by segmental (17.9%), while the least frequency was for massive pulmonary embolism (12.5%).Conclusion: VTE is a common event in COVID-19 patients, where smoking and malignancy more frequent, D dimer is significantly elevated, and more morbidity and mortality in those patients.

Download Full-text

Case Reports of Pregnancy-Related Cerebral Venous Thrombosis in the Neurology Department of the Emergency Clinical Hospital in Constanta

Life ◽

10.3390/life12010090 ◽

2022 ◽

Vol 12 (1) ◽

pp. 90

Author(s):

Any Docu Axelerad ◽

Lavinia Alexandra Zlotea ◽

Carmen Adella Sirbu ◽

Alina Zorina Stroe ◽

Silviu Docu Axelerad ◽

...

Keyword(s):

Risk Factors ◽

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Sinus Thrombosis ◽

Young Patients ◽

Clinical Manifestations ◽

Special Treatment ◽

Lateral Sinus ◽

Cortical Vein ◽

Cortical Vein Thrombosis

Cerebral venous thrombosis accounts for 0.5–1% of all cerebrovascular events and is one type of stroke that affects the veins and cerebral sinuses. Females are more affected than males, as they may have risk factors, such as pregnancy, first period after pregnancy, treatment with oral contraceptives treatment with hormonal replacement, or hereditary thrombophilia. This neurological pathology may endanger a patient’s life. However, it must be suspected in its acute phase, when it presents with variable clinical characteristics, so that special treatment can be initiated to achieve a favorable outcome with partial or complete functional recovery. The case study describes the data and the treatment of two patients with confirmed cerebral venous thrombosis with various localizations and associated risk factors, who were admitted to the neurology department of the Sf. Apostol Andrei Emergency Hospital in Constanta. The first patient was 40 years old and affected by sigmoid sinus and right lateral sinus thrombosis, inferior sagittal sinus, and right sinus thrombosis, associated with right temporal subacute cortical and subcortical hemorrhage, which appeared following a voluntary abortion. The second case was a patient aged 25 who was affected by left parietal cortical vein thrombosis, associated with ipsilateral superior parietal subcortical venous infarction, which appeared following labor. The data are strictly observational and offer a perspective on clinical manifestations and clinical and paraclinical investigations, including the treatment of young patients who had been diagnosed with cerebral venous thrombosis and admitted to the neurology department.

Download Full-text